DE19812160C1 - Formkörper aus wirkstoffhaltigen thermoplastischen Polyurethanen - Google Patents

Formkörper aus wirkstoffhaltigen thermoplastischen Polyurethanen

Info

Publication number
DE19812160C1
DE19812160C1 DE19812160A DE19812160A DE19812160C1 DE 19812160 C1 DE19812160 C1 DE 19812160C1 DE 19812160 A DE19812160 A DE 19812160A DE 19812160 A DE19812160 A DE 19812160A DE 19812160 C1 DE19812160 C1 DE 19812160C1
Authority
DE
Germany
Prior art keywords
polyurethane
antibiotic
active ingredient
polymer
ciprofloxacin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE19812160A
Other languages
German (de)
English (en)
Inventor
Reinhard Dipl Chem Dr Albers
Ralf Dipl Chem Dr Dujardin
Heinz Dipl Chem Dr Pudleiner
Joachim Dipl Chem Dr Simon
Guenther Dipl Biol Dr Eberz
Wolfgang Dipl Chem Dr Kreis
Christina Prof Dr Krasemann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Innovation GmbH
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE19812160A priority Critical patent/DE19812160C1/de
Application filed by Bayer AG filed Critical Bayer AG
Priority to AU33298/99A priority patent/AU737881B2/en
Priority to KR1020007010354A priority patent/KR20010042020A/ko
Priority to PCT/EP1999/001536 priority patent/WO1999048542A1/de
Priority to PL99342952A priority patent/PL193574B1/pl
Priority to CA002324365A priority patent/CA2324365C/en
Priority to IL13789699A priority patent/IL137896A0/xx
Priority to JP2000537586A priority patent/JP2002507457A/ja
Priority to US09/646,339 priority patent/US6723333B1/en
Priority to HK01107360.6A priority patent/HK1036599B/xx
Priority to NZ506969A priority patent/NZ506969A/en
Priority to EP99914501A priority patent/EP1067974A1/de
Priority to CNB998040002A priority patent/CN1191868C/zh
Application granted granted Critical
Publication of DE19812160C1 publication Critical patent/DE19812160C1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04—Macromolecular materials
    • A61L29/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C08G18/12—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step using two or more compounds having active hydrogen in the first polymerisation step
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/65—Low-molecular-weight compounds having active hydrogen with high-molecular-weight compounds having active hydrogen
    • C08G18/66—Compounds of groups C08G18/42, C08G18/48, or C08G18/52
    • C08G18/6666—Compounds of group C08G18/48 or C08G18/52
    • C08G18/667—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38
    • C08G18/6674—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38 with compounds of group C08G18/3203
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • C08K5/0058—Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Materials For Medical Uses (AREA)
DE19812160A 1998-03-20 1998-03-20 Formkörper aus wirkstoffhaltigen thermoplastischen Polyurethanen Expired - Fee Related DE19812160C1 (de)

Priority Applications (13)

Application Number Priority Date Filing Date Title
DE19812160A DE19812160C1 (de) 1998-03-20 1998-03-20 Formkörper aus wirkstoffhaltigen thermoplastischen Polyurethanen
US09/646,339 US6723333B1 (en) 1998-03-20 1999-03-10 Moulded bodies made of thermoplastic polyurethane containing an active substance
PCT/EP1999/001536 WO1999048542A1 (de) 1998-03-20 1999-03-10 Formkörper aus wirkstoffhaltigen thermoplastischen polyurethanen
PL99342952A PL193574B1 (pl) 1998-03-20 1999-03-10 Formowane wyroby, wykonane z termoplastycznie przetwarzalnego poliuretanu
CA002324365A CA2324365C (en) 1998-03-20 1999-03-10 Moulded bodies made of thermoplastic polyurethane containing an active substance
IL13789699A IL137896A0 (en) 1998-03-20 1999-03-10 Moulded bodies made of thermoplastic polyurethane containing an active substance
AU33298/99A AU737881B2 (en) 1998-03-20 1999-03-10 Moulded items made from active substance-containing thermoplastic polyurethanes
KR1020007010354A KR20010042020A (ko) 1998-03-20 1999-03-10 활성 물질-함유 열가소성 폴리우레탄으로부터 제조된 성형품
HK01107360.6A HK1036599B (en) 1998-03-20 1999-03-10 Moulded items made from active substance-containing thermoplastic polyurethanes
NZ506969A NZ506969A (en) 1998-03-20 1999-03-10 Moulded items made of thermoplastic polyurethane containing an antibiotic substance
EP99914501A EP1067974A1 (de) 1998-03-20 1999-03-10 Formkörper aus wirkstoffhaltigen thermoplastischen polyurethanen
CNB998040002A CN1191868C (zh) 1998-03-20 1999-03-10 由含活性物质的热塑性聚氨酯制造的模塑制品
JP2000537586A JP2002507457A (ja) 1998-03-20 1999-03-10 活性物質含有熱可塑性ポリウレタンから製造された成形品

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19812160A DE19812160C1 (de) 1998-03-20 1998-03-20 Formkörper aus wirkstoffhaltigen thermoplastischen Polyurethanen

Publications (1)

Publication Number Publication Date
DE19812160C1 true DE19812160C1 (de) 1999-07-08

Family

ID=7861603

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19812160A Expired - Fee Related DE19812160C1 (de) 1998-03-20 1998-03-20 Formkörper aus wirkstoffhaltigen thermoplastischen Polyurethanen

Country Status (12)

Country Link
US (1) US6723333B1 (enExample)
EP (1) EP1067974A1 (enExample)
JP (1) JP2002507457A (enExample)
KR (1) KR20010042020A (enExample)
CN (1) CN1191868C (enExample)
AU (1) AU737881B2 (enExample)
CA (1) CA2324365C (enExample)
DE (1) DE19812160C1 (enExample)
IL (1) IL137896A0 (enExample)
NZ (1) NZ506969A (enExample)
PL (1) PL193574B1 (enExample)
WO (1) WO1999048542A1 (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1149851A1 (de) * 2000-04-25 2001-10-31 Bayer Ag Aliphatische thermoplastische Polyurethane und ihre Verwendung
EP1188787A1 (en) * 2000-08-30 2002-03-20 Hammond Group, Inc. Synthetic polymer compositions containing antibiotics as antidegradents
WO2002041929A1 (de) 2000-11-21 2002-05-30 Schering Ag Röhrenförmige gefässimplantate (stents) sowie verfahren zur deren herstellung
WO2007039157A1 (de) * 2005-10-06 2007-04-12 Bayer Innovation Gmbh Verfahren zur herstellung antimikrobieller kunststoffzusammensetzungen
DE102009025293A1 (de) 2009-06-15 2010-12-16 Adolf Pfaff & Dr. Karl-Friedrich Reichenbach GbR (vertretungsberechtigter Gesellschafter: Adolf Pfaff, 79183 Waldkirch) Radioopake Formgedächtnis-Polymere
US8534557B2 (en) 2006-03-22 2013-09-17 Bayer Innovation Gmbh Method and device for reading information optically

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4199485B2 (ja) * 2002-06-07 2008-12-17 久光製薬株式会社 貼付剤
AU2004210399B2 (en) * 2003-02-10 2010-02-18 Bayer Intellectual Property Gmbh Treatment of bacterial diseases of the respiratory organs by locally applying fluoroquinolones
CN1305534C (zh) * 2003-10-16 2007-03-21 华南理工大学 聚氨脂医用抗感染介入导管的制备方法
DE102004054040A1 (de) * 2004-11-05 2006-05-11 Bayer Innovation Gmbh Wirkstoffhaltige Silikonelastomere
DE102005028056A1 (de) * 2005-06-16 2006-12-21 Basf Ag Thermoplastisches Polyurethan enthaltend Isocyanat
DE102006020644A1 (de) * 2006-04-28 2007-10-31 Bayer Innovation Gmbh Antiseptikahaltige Silikonelastomere
DE102007006761A1 (de) * 2007-02-12 2008-08-14 Bayer Innovation Gmbh Teilneutralisierte Wirkstoffe enthaltende Polymerformmassen
US8747883B2 (en) 2010-06-02 2014-06-10 Princeton Trade & Technology, Inc. Medical item for long term drug release
US11033624B2 (en) * 2010-06-02 2021-06-15 Novaflux Inc. Medical item for prevention and treatment of ear infection
US10285865B2 (en) 2014-05-02 2019-05-14 Novaflux Inc. Drug-releasing device usable in mucosal body cavities
CN107603190A (zh) * 2017-09-21 2018-01-19 河南驼人医疗器械集团有限公司 一种医用抗菌聚氨酯材料及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4143239A1 (de) * 1991-12-31 1993-07-01 Joerg Dipl Chem Schierholz Pharmazeutische wirkstoffe enthaltende implantierbare vorrichtung aus einem polymeren material sowie verfahren zu deren herstellung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019096A (en) 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US5165952A (en) * 1989-01-18 1992-11-24 Becton, Dickinson And Company Anti-infective and antithrombogenic medical articles and method for their preparation
US5344455A (en) * 1992-10-30 1994-09-06 Medtronic, Inc. Graft polymer articles having bioactive surfaces
DE4428458A1 (de) * 1994-08-11 1996-02-15 Bayer Ag Cycloaliphatische thermoplastische Polyurethanelastomere
WO1996022114A1 (en) * 1995-01-18 1996-07-25 Vitaphore Corporation An antimicrobial medical device and method
US5624704A (en) * 1995-04-24 1997-04-29 Baylor College Of Medicine Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent
DE19638570A1 (de) * 1996-09-20 1998-03-26 Bayer Ag Wirkstoffhaltige thermoplastische Polyurethane

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4143239A1 (de) * 1991-12-31 1993-07-01 Joerg Dipl Chem Schierholz Pharmazeutische wirkstoffe enthaltende implantierbare vorrichtung aus einem polymeren material sowie verfahren zu deren herstellung

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1149851A1 (de) * 2000-04-25 2001-10-31 Bayer Ag Aliphatische thermoplastische Polyurethane und ihre Verwendung
US6632866B2 (en) 2000-04-25 2003-10-14 Bayer Aktiengesellschaft Aliphatic thermoplastic polyurethanes and use thereof
US6706807B2 (en) 2000-04-25 2004-03-16 Bayer Aktiengesellschaft Aliphatic thermoplastic polyurethanes and use thereof
EP1188787A1 (en) * 2000-08-30 2002-03-20 Hammond Group, Inc. Synthetic polymer compositions containing antibiotics as antidegradents
WO2002041929A1 (de) 2000-11-21 2002-05-30 Schering Ag Röhrenförmige gefässimplantate (stents) sowie verfahren zur deren herstellung
WO2007039157A1 (de) * 2005-10-06 2007-04-12 Bayer Innovation Gmbh Verfahren zur herstellung antimikrobieller kunststoffzusammensetzungen
US8534557B2 (en) 2006-03-22 2013-09-17 Bayer Innovation Gmbh Method and device for reading information optically
DE102009025293A1 (de) 2009-06-15 2010-12-16 Adolf Pfaff & Dr. Karl-Friedrich Reichenbach GbR (vertretungsberechtigter Gesellschafter: Adolf Pfaff, 79183 Waldkirch) Radioopake Formgedächtnis-Polymere

Also Published As

Publication number Publication date
NZ506969A (en) 2003-07-25
IL137896A0 (en) 2001-10-31
HK1036599A1 (en) 2002-01-11
CN1191868C (zh) 2005-03-09
CA2324365A1 (en) 1999-09-30
CN1293579A (zh) 2001-05-02
WO1999048542A1 (de) 1999-09-30
PL193574B1 (pl) 2007-02-28
AU737881B2 (en) 2001-09-06
KR20010042020A (ko) 2001-05-25
AU3329899A (en) 1999-10-18
US6723333B1 (en) 2004-04-20
JP2002507457A (ja) 2002-03-12
CA2324365C (en) 2009-01-20
EP1067974A1 (de) 2001-01-17
PL342952A1 (en) 2001-07-16

Similar Documents

Publication Publication Date Title
DE19812160C1 (de) Formkörper aus wirkstoffhaltigen thermoplastischen Polyurethanen
EP1128723B1 (de) Wirkstoffhaltige aromatische copolyester
EP0927222B1 (de) Wirkstoffhaltige thermoplastische polyurethane
DE69112911T2 (de) Bruchbeständige Polyurethancarbonatpolymerprothesen.
DE69629820T2 (de) Fluoroligomere oberflächen modifizierungsmittel für polymere und die hieraus hergestellte gegenstände
EP1937765B1 (de) Verfahren zur herstellung antimikrobieller kunststoffzusammensetzungen
EP1940938B1 (de) Antimikrobielle kunststoffzusammensetzung mit niedriger elutionsrate und langer wirksamkeit
EP1128724B1 (de) Wirkstoffhaltige polyetherblockamide
EP2120552A1 (de) Teilneutralisierte wirkstoffe enthaltende polymerformmassen
EP0929589B1 (de) Verwendung biokompatibler thermoplastischer polyurethane
DE9117117U1 (de) Bruchbeständige Polyurethancarbonatpolymerprothesen
HK1036599B (en) Moulded items made from active substance-containing thermoplastic polyurethanes

Legal Events

Date Code Title Description
8100 Publication of patent without earlier publication of application
D1 Grant (no unexamined application published) patent law 81
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BAYER MATERIALSCIENCE AG, 51373 LEVERKUSEN, DE

8327 Change in the person/name/address of the patent owner

Owner name: BAYER INNOVATION GMBH, 40225 DUESSELDORF, DE

R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee

Effective date: 20111001