DE19711785A1 - Endothelin-Rezeptor-Antagonisten - Google Patents

Endothelin-Rezeptor-Antagonisten

Info

Publication number
DE19711785A1
DE19711785A1 DE19711785A DE19711785A DE19711785A1 DE 19711785 A1 DE19711785 A1 DE 19711785A1 DE 19711785 A DE19711785 A DE 19711785A DE 19711785 A DE19711785 A DE 19711785A DE 19711785 A1 DE19711785 A1 DE 19711785A1
Authority
DE
Germany
Prior art keywords
cyclopenta
inden
methoxyphenyl
carboxylic acid
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19711785A
Other languages
German (de)
English (en)
Inventor
Werner Dr Mederski
Dieter Dr Dorsch
Claudia Dr Wilm
Mathias Dr Oswald
Claus-Jochen Dr Schmitges
Maria Christadler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Priority to DE19711785A priority Critical patent/DE19711785A1/de
Priority to AU68265/98A priority patent/AU6826598A/en
Priority to PCT/EP1998/001206 priority patent/WO1998042709A1/de
Priority to ZA982359A priority patent/ZA982359B/xx
Priority to ARP980101274A priority patent/AR010909A1/es
Publication of DE19711785A1 publication Critical patent/DE19711785A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19711785A 1997-03-21 1997-03-21 Endothelin-Rezeptor-Antagonisten Withdrawn DE19711785A1 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE19711785A DE19711785A1 (de) 1997-03-21 1997-03-21 Endothelin-Rezeptor-Antagonisten
AU68265/98A AU6826598A (en) 1997-03-21 1998-03-04 Endothelin-receptor antagonists
PCT/EP1998/001206 WO1998042709A1 (de) 1997-03-21 1998-03-04 Endothelin-rezeptor-antagonisten
ZA982359A ZA982359B (en) 1997-03-21 1998-03-19 Endothelin-receptor-antagonists
ARP980101274A AR010909A1 (es) 1997-03-21 1998-03-20 Derivados sustituidos de 8-(aza u oxa o tia)-3-aza-ciclopenta[a]inden como antagonistas del receptor endotelial, procedimiento para prepararlos ,procedimiento para obtener composiciones farmaceuticas a base de los derivados, medicamentos y composiciones farmaceuticas que los contienen.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19711785A DE19711785A1 (de) 1997-03-21 1997-03-21 Endothelin-Rezeptor-Antagonisten

Publications (1)

Publication Number Publication Date
DE19711785A1 true DE19711785A1 (de) 1998-09-24

Family

ID=7824108

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19711785A Withdrawn DE19711785A1 (de) 1997-03-21 1997-03-21 Endothelin-Rezeptor-Antagonisten

Country Status (5)

Country Link
AR (1) AR010909A1 (xx)
AU (1) AU6826598A (xx)
DE (1) DE19711785A1 (xx)
WO (1) WO1998042709A1 (xx)
ZA (1) ZA982359B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10155076A1 (de) * 2001-11-09 2003-05-22 Merck Patent Gmbh Verwendung von Endothelin-Rezeptor-Antagonisten zur Behandlung von Tumorerkrankungen
US8053603B2 (en) 2006-01-06 2011-11-08 Sunovion Pharmaceuticals Inc. Tetralone-based monoamine reuptake inhibitors
KR101294014B1 (ko) 2006-01-06 2013-08-09 선오비온 파마슈티컬스 인코포레이티드 모노아민 재흡수 저해제로서의 시클로알킬아민
PT2816024T (pt) 2006-03-31 2017-10-20 Sunovion Pharmaceuticals Inc Aminas quirais
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US7902252B2 (en) 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
RU2470011C2 (ru) 2007-05-31 2012-12-20 Сепракор Инк. Циклоалкиламины, содержащие в качестве заместителя фенил, как ингибиторы обратного захвата моноаминов

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995033748A1 (en) * 1994-06-09 1995-12-14 Smithkline Beecham Corporation Endothelin receptor antagonists

Also Published As

Publication number Publication date
WO1998042709A1 (de) 1998-10-01
AU6826598A (en) 1998-10-20
ZA982359B (en) 1998-09-22
AR010909A1 (es) 2000-07-12

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee