DE179430T1 - Waessrige arzneiformulierungen des piroxicammonohydrats. - Google Patents
Waessrige arzneiformulierungen des piroxicammonohydrats.Info
- Publication number
- DE179430T1 DE179430T1 DE198585113339T DE85113339T DE179430T1 DE 179430 T1 DE179430 T1 DE 179430T1 DE 198585113339 T DE198585113339 T DE 198585113339T DE 85113339 T DE85113339 T DE 85113339T DE 179430 T1 DE179430 T1 DE 179430T1
- Authority
- DE
- Germany
- Prior art keywords
- piroxicam
- monohydrate
- pharmaceutical preparations
- active ingredient
- aqueous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- SDJQUPRVYCURBW-UHFFFAOYSA-N 4-hydroxy-2-methyl-1,1-dioxo-n-pyridin-2-yl-1$l^{6},2-benzothiazine-3-carboxamide;hydrate Chemical compound O.OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 SDJQUPRVYCURBW-UHFFFAOYSA-N 0.000 title claims 5
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 claims abstract 4
- 239000000825 pharmaceutical preparation Substances 0.000 claims 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000012736 aqueous medium Substances 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 150000007529 inorganic bases Chemical class 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 150000007522 mineralic acids Chemical class 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 150000007524 organic acids Chemical class 0.000 claims 1
- 150000007530 organic bases Chemical class 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical class OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 claims 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 239000012266 salt solution Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
- PGBYMPJXTSIZEC-UHFFFAOYSA-N 4-hydroxy-2-methyl-n-pyridin-2-yl-1,2-benzothiazine-3-carboxamide Chemical compound CN1SC2=CC=CC=C2C(O)=C1C(=O)NC1=CC=CC=N1 PGBYMPJXTSIZEC-UHFFFAOYSA-N 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT23263/84A IT1196307B (it) | 1984-10-22 | 1984-10-22 | Formulazioni farmaceutiche acquose di piroxicam monoidrato |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE179430T1 true DE179430T1 (de) | 1988-02-04 |
Family
ID=11205417
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE198585113339T Pending DE179430T1 (de) | 1984-10-22 | 1985-10-21 | Waessrige arzneiformulierungen des piroxicammonohydrats. |
| DE8585113339T Expired - Lifetime DE3583916D1 (de) | 1984-10-22 | 1985-10-21 | Waessrige arzneiformulierungen des piroxicammonohydrats. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8585113339T Expired - Lifetime DE3583916D1 (de) | 1984-10-22 | 1985-10-21 | Waessrige arzneiformulierungen des piroxicammonohydrats. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4824841A (enExample) |
| EP (1) | EP0179430B1 (enExample) |
| JP (1) | JPS61100521A (enExample) |
| KR (1) | KR880002265B1 (enExample) |
| AT (1) | ATE66605T1 (enExample) |
| DE (2) | DE179430T1 (enExample) |
| IT (1) | IT1196307B (enExample) |
| MY (1) | MY102929A (enExample) |
| PH (1) | PH23003A (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1241088B (it) * | 1990-03-27 | 1993-12-29 | Chiesi Farma Spa | Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche |
| ATE95421T1 (de) * | 1990-04-26 | 1993-10-15 | Sagitta Arzneimittel Gmbh | Piroxicam enthaltende pharmazeutische zusammensetzung zur topischen anwendung. |
| JP3031990B2 (ja) * | 1990-10-19 | 2000-04-10 | 同仁医薬化工株式会社 | 消炎鎮痛クリーム剤組成物 |
| JP2566488Y2 (ja) * | 1991-08-19 | 1998-03-25 | 積水ハウス株式会社 | 通路側方の雪留め及び巻き垂れ防止構造 |
| HU209518B (en) * | 1992-12-23 | 1994-06-28 | Egyt Gyogyszervegyeszeti Gyar | Process for production of free of skin damaging effect unguent preparation containing piroxicam |
| US5436241A (en) * | 1994-01-14 | 1995-07-25 | Bristol-Myers Squibb Company | Topical anti-inflammatory compositions containing piroxicam |
| US5807568A (en) * | 1994-12-27 | 1998-09-15 | Mcneil-Ppc, Inc. | Enhanced delivery of topical compositions containing flurbiprofen |
| IT1286496B1 (it) * | 1996-11-20 | 1998-07-15 | Leetrim Ltd Dublin | Composizione farmaceutica orale ad attivita' antipiretica,analgesica ed antiinfiammatoria |
| EP0945131A1 (de) * | 1998-03-27 | 1999-09-29 | Boehringer Ingelheim Pharma KG | Perorale Wirkstoff-Suspension |
| US6184220B1 (en) | 1998-03-27 | 2001-02-06 | Boehringer Ingelheim Pharma Kg | Oral suspension of pharmaceutical substance |
| US7321828B2 (en) * | 1998-04-13 | 2008-01-22 | Isis Pharmaceuticals, Inc. | System of components for preparing oligonucleotides |
| FR2787322B1 (fr) * | 1998-12-18 | 2002-10-18 | Galderma Res & Dev | Emulsion huile-dans-eau comprenant un agent actif micronise et un systeme emulsionnant approprie |
| US20020035107A1 (en) | 2000-06-20 | 2002-03-21 | Stefan Henke | Highly concentrated stable meloxicam solutions |
| DE10161077A1 (de) | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
| US8992980B2 (en) | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
| EP1568369A1 (en) | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
| US9101529B2 (en) | 2009-10-12 | 2015-08-11 | Boehringer Ingelheim Vetmedica Gmbh | Containers for compositions comprising meloxicam |
| WO2011107150A1 (en) | 2010-03-03 | 2011-09-09 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats |
| US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
| MX357376B (es) * | 2011-06-22 | 2018-07-06 | Laboratorios Senosiain S A De C V Star | Composicion farmaceutica para uso en inflamacion y dolor. |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3853862A (en) * | 1973-04-23 | 1974-12-10 | Pfizer | Production of 4-hydroxy-1,2-benzothiazine-3-carboxamides |
| US4074048A (en) * | 1976-05-10 | 1978-02-14 | Warner-Lambert Company | Process for the preparation of 4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides |
| US4309427A (en) * | 1981-01-15 | 1982-01-05 | Pfizer Inc. | Benzothiazine dioxide derivatives |
| US4434163A (en) * | 1981-06-01 | 1984-02-28 | Pfizer Inc. | Water-soluble benzothiazine dioxide salts |
| US4434164A (en) * | 1981-06-01 | 1984-02-28 | Pfizer Inc. | Crystalline benzothiazine dioxide salts |
| CA1197244A (en) * | 1982-04-16 | 1985-11-26 | Medichem, S.A. | Process for the preparation of 4-hydroxy-2-methyl-2h- 1,2-benzothiazine-3-carboxamide-1,1-dioxides |
| JPS5913714A (ja) * | 1982-07-13 | 1984-01-24 | Taito Pfizer Kk | 外用消炎鎮痛剤 |
| DE3311165A1 (de) * | 1983-03-26 | 1984-09-27 | Gödecke AG, 1000 Berlin | Feinkristallines isoxicam |
| DE3437232A1 (de) * | 1984-10-10 | 1986-04-17 | Mack Chem Pharm | Stabilisierte injektionsloesungen von piroxicam |
| US4636498A (en) * | 1984-10-11 | 1987-01-13 | Pfizer Inc. | Formulation of antiinflammatory drugs |
-
1984
- 1984-10-22 IT IT23263/84A patent/IT1196307B/it active
-
1985
- 1985-10-21 EP EP85113339A patent/EP0179430B1/en not_active Expired - Lifetime
- 1985-10-21 DE DE198585113339T patent/DE179430T1/de active Pending
- 1985-10-21 AT AT85113339T patent/ATE66605T1/de not_active IP Right Cessation
- 1985-10-21 KR KR1019850007751A patent/KR880002265B1/ko not_active Expired
- 1985-10-21 DE DE8585113339T patent/DE3583916D1/de not_active Expired - Lifetime
- 1985-10-22 JP JP60237159A patent/JPS61100521A/ja active Granted
- 1985-10-22 PH PH32958A patent/PH23003A/en unknown
-
1986
- 1986-12-15 US US06/941,819 patent/US4824841A/en not_active Expired - Fee Related
-
1987
- 1987-09-29 MY MYPI87002295A patent/MY102929A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IT8423263A1 (it) | 1986-04-22 |
| ATE66605T1 (de) | 1991-09-15 |
| JPH0333128B2 (enExample) | 1991-05-16 |
| DE3583916D1 (de) | 1991-10-02 |
| KR880002265B1 (ko) | 1988-10-21 |
| PH23003A (en) | 1989-02-24 |
| IT8423263A0 (it) | 1984-10-22 |
| US4824841A (en) | 1989-04-25 |
| MY102929A (en) | 1993-03-31 |
| IT1196307B (it) | 1988-11-16 |
| EP0179430A2 (en) | 1986-04-30 |
| EP0179430A3 (en) | 1987-07-01 |
| KR860003249A (ko) | 1986-05-21 |
| EP0179430B1 (en) | 1991-08-28 |
| JPS61100521A (ja) | 1986-05-19 |
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