DE1695445A1 - Verfahren zur Herstellung von Ribonucleosid-Verbindungen - Google Patents

Verfahren zur Herstellung von Ribonucleosid-Verbindungen

Info

Publication number
DE1695445A1
DE1695445A1 DE19661695445 DE1695445A DE1695445A1 DE 1695445 A1 DE1695445 A1 DE 1695445A1 DE 19661695445 DE19661695445 DE 19661695445 DE 1695445 A DE1695445 A DE 1695445A DE 1695445 A1 DE1695445 A1 DE 1695445A1
Authority
DE
Germany
Prior art keywords
alkyl
compound
trityl
compounds
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19661695445
Other languages
German (de)
English (en)
Inventor
Tsung-Ying Shen
Ruyle William Vance
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1695445A1 publication Critical patent/DE1695445A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19661695445 1965-04-01 1966-03-31 Verfahren zur Herstellung von Ribonucleosid-Verbindungen Pending DE1695445A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US444808A US3322747A (en) 1965-04-01 1965-04-01 Thionocarbonate nucleosides

Publications (1)

Publication Number Publication Date
DE1695445A1 true DE1695445A1 (de) 1971-04-15

Family

ID=23766442

Family Applications (3)

Application Number Title Priority Date Filing Date
DE19661695445 Pending DE1695445A1 (de) 1965-04-01 1966-03-31 Verfahren zur Herstellung von Ribonucleosid-Verbindungen
DE19661595989 Pending DE1595989A1 (de) 1965-04-01 1966-03-31 Ribonucleoside und Verfahren zu deren Herstellung
DE19661695412 Pending DE1695412A1 (de) 1965-04-01 1966-03-31 Verfahren zur Herstellung von Ribonucleosid-Verbindungen

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE19661595989 Pending DE1595989A1 (de) 1965-04-01 1966-03-31 Ribonucleoside und Verfahren zu deren Herstellung
DE19661695412 Pending DE1695412A1 (de) 1965-04-01 1966-03-31 Verfahren zur Herstellung von Ribonucleosid-Verbindungen

Country Status (6)

Country Link
US (1) US3322747A (enExample)
CH (1) CH482688A (enExample)
DE (3) DE1695445A1 (enExample)
FR (1) FR1482902A (enExample)
GB (3) GB1111989A (enExample)
NL (1) NL6604388A (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0348170A3 (en) * 1988-06-21 1990-12-05 Moses Nam Fong Lee Antiviral pyrimidine derivatives
EP0334368A3 (en) * 1988-03-24 1991-12-27 Bristol-Myers Squibb Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3463850A (en) * 1967-01-03 1969-08-26 Merck & Co Inc Arabinofuranosyl 2-thiopyrimidines and pharmaceutical compositions thereof
SE391183B (sv) * 1971-04-15 1977-02-07 Asahi Chemical Ind 2',3'-0-sulfinylcytidin och syraadditionssalter derav till anvendning som mellanprodukt for framstellning av 2,2'-anhydro-(1-beta-d-arabinofuranosyl) cytosin
JPS535311B2 (enExample) * 1974-01-30 1978-02-25
US4112221A (en) * 1974-07-17 1978-09-05 Asahi Kasei Kogyo Kabushiki Kaisha Process for preparing 8,2'-O-anhydropurine nucleosides
JPS5176297A (en) * 1974-12-27 1976-07-01 Asahi Chemical Ind 2*2**anhidoroshichijin 5** rinsanesuterunoseizohoho
US4978655A (en) * 1986-12-17 1990-12-18 Yale University Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses
US5212294A (en) * 1988-03-24 1993-05-18 Bristol-Myers Squibb Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides
EP0342422A3 (en) * 1988-05-16 1990-12-05 F. Hoffmann-La Roche Ag Process for the preparation of 2',3'-dideoxynucleosides, and intermediates used therein
US5008384A (en) * 1988-07-12 1991-04-16 Pfizer Inc. Process for the production of O.sup. 2,2'-anhydro-1-(β-D-arabinofuranosyl)thymine
FI922014A0 (fi) * 1989-11-06 1992-05-05 Nycomed As Nukleosidderivat.
JP2526414B2 (ja) * 1994-05-20 1996-08-21 工業技術院長 制ガン剤エステル化合物及びその製造方法
WO2008115499A1 (en) * 2007-03-19 2008-09-25 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The University Of Oregon Mannich base n-oxide drugs

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0334368A3 (en) * 1988-03-24 1991-12-27 Bristol-Myers Squibb Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides
EP0348170A3 (en) * 1988-06-21 1990-12-05 Moses Nam Fong Lee Antiviral pyrimidine derivatives

Also Published As

Publication number Publication date
CH482688A (de) 1969-12-15
GB1111990A (en) 1968-05-01
NL6604388A (enExample) 1966-10-03
GB1111989A (en) 1968-05-01
GB1111988A (en) 1968-05-01
FR1482902A (fr) 1967-06-02
DE1695412A1 (de) 1971-04-15
DE1595989A1 (de) 1970-03-19
US3322747A (en) 1967-05-30

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