DE1139610B - Process for the preservation of nonionic, cosmetic and pharmaceutical emulsions - Google Patents

Process for the preservation of nonionic, cosmetic and pharmaceutical emulsions

Info

Publication number
DE1139610B
DE1139610B DED35559A DED0035559A DE1139610B DE 1139610 B DE1139610 B DE 1139610B DE D35559 A DED35559 A DE D35559A DE D0035559 A DED0035559 A DE D0035559A DE 1139610 B DE1139610 B DE 1139610B
Authority
DE
Germany
Prior art keywords
cosmetic
nonionic
preservation
preservatives
emulsions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DED35559A
Other languages
German (de)
Inventor
Gustav Nowak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gerberding & Co GmbH
Dragoco Spezialfabrik Konz Riech- und Aromastoffe
Original Assignee
Gerberding & Co GmbH
Dragoco Spezialfabrik Konz Riech- und Aromastoffe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gerberding & Co GmbH, Dragoco Spezialfabrik Konz Riech- und Aromastoffe filed Critical Gerberding & Co GmbH
Priority to DED35559A priority Critical patent/DE1139610B/en
Publication of DE1139610B publication Critical patent/DE1139610B/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT, VEGETABLES, EDIBLE SEEDS; CHEMICAL RIPENING OF FRUIT OR VEGETABLES; THE PRESERVED, RIPENED, OR CANNED PRODUCTS
    • A23B5/00Preservation of eggs or egg products
    • A23B5/06Coating eggs with a protective layer; Compositions or apparatus therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D7/00Edible oil or fat compositions containing an aqueous phase, e.g. margarines
    • A23D7/06Preservation of finished products
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00Drying solid materials or objects by processes involving the application of heat
    • F26B3/02Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • F26B3/10Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it
    • F26B3/12Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it in the form of a spray, i.e. sprayed or dispersed emulsions or suspensions

Description

Verfahren zur Konservierung nichtionischer, kosmetischer und pharmazeutischer Emulsionen Die Erfindung bezieht sich auf ein Verfahren zur Konservierung nichtionischer, kosmetischer und pharmazeutischer Emulsionen, wie Salbengrundlagen u. ä. Sie besteht darin, daß als Konservierungsmittel Alkylester der Sorbinsäure verwendet werden.Process for the preservation of nonionic, cosmetic and pharmaceutical Emulsions The invention relates to a method for preserving nonionic, cosmetic and pharmaceutical emulsions, such as ointment bases and the like in that alkyl esters of sorbic acid are used as preservatives.

Es ist an sich bekannt, daß phenolische Konservierungsmittel, wie die bekannten, auch in der Lebensmittelindustrie zugelassenen p-Hydroxybenzoesäureester durch nichtionogene Emulgatoren vom Typ der polyoxäthylierten Fettsäureester weitgehend inaktiviert werden. Eine Inaktivierung der eingangs erwähnten phenolischen Konservierungsmittel tritt aber auch durch andere makromolekulare Verbindungen, wie Polyäthylenglykole, Polyvinylpyrrolidon, Methylcellulose, Gelatine usw., ein. Es ist daher ein Problem der einschlägigen Technik, kosmetische und pharmazeutische Zubereitungen mit einem Gehalt an nichtionogenen Emulgatoren oder anderen makromolekularen Verbindungen dauernd, sicher und im pH-Bereich über 7 gegen Schimmelpilz- und Bakterienbefall zu schützen. Die in der Lebensmitteltechnik vielfach als Konservierungsmittel noch benutzte Sorbinsäure ist bei Anwesenheit makromolekularer bzw. nichtionischer Emulgatoren nur im sauren Bereich wirksam, sie versagt aber bei der Konservierung von neutralen und alkalischen Emulsionen.It is known per se that phenolic preservatives such as the well-known p-hydroxybenzoic acid esters, also approved in the food industry largely by non-ionic emulsifiers of the polyoxyethylated fatty acid ester type be inactivated. Inactivation of the phenolic preservatives mentioned at the beginning but also occurs through other macromolecular compounds, such as polyethylene glycols, Polyvinyl pyrrolidone, methyl cellulose, gelatin, etc. It is therefore a problem the relevant technology, cosmetic and pharmaceutical preparations with one Content of non-ionic emulsifiers or other macromolecular compounds permanent, safe and in the pH range above 7 against mold and bacterial attack to protect. In food technology, they are still often used as preservatives The sorbic acid used is in the presence of macromolecular or nonionic emulsifiers only effective in the acidic range, but it fails to preserve neutral ones and alkaline emulsions.

Es war überraschend und darin besteht die Erfindung, daß sich kosmetische und pharmazeutische Zubereitungen, insbesondere Emulsionen durch Zusatz von 0,1 bis 1%, vorwiegend 0,3%, von Alkylestern der Sorbinsäure auch im neutralen und alkalischen pH-Bereich konservieren lassen.It was surprising and that is the invention that cosmetic and pharmaceutical preparations, especially emulsions with the addition of 0.1 up to 1%, predominantly 0.3%, of alkyl esters of sorbic acid, also in neutral and alkaline acids Allow the pH range to be preserved.

Die vorwiegend in Frage kommenden Äthyl-, Propyl- und Isopropylester der Sorbinsäure werden nach an und für sich bekannten Verfahren hergestellt und stellen wasserklare Flüssigkeiten mit einem angenehmen, leicht fruchtigen Geruch dar, der der erfindungsgemäßen Verwendung in keiner Weise entgegensteht.The predominantly suitable ethyl, propyl and isopropyl esters the sorbic acid are prepared and according to processes known per se represent water-clear liquids with a pleasant, slightly fruity smell represents, which in no way precludes the use according to the invention.

Claims (2)

PATENTANSPRÜCHE 1. Die Verwendung von Alkylestern der Sorbinsäure, insbesondere der Äthyl-, Propyl- und Isopropylester als Konservierungsmittel nichtionischer, kosmetischer und pharmazeutischer Zubereitungen, wie Emulsionen, im pH-Bereich über PH = 7. PATENT CLAIMS 1. The use of alkyl esters of sorbic acid, in particular the ethyl, propyl and isopropyl esters as non-ionic preservatives, cosmetic and pharmaceutical preparations, such as emulsions, in the pH range above PH = 7. 2. Die Verwendung von Alkylestern der Sorbinsäure nach Anspruch 1, dadurch gekennzeichnet, daß die vor Schimmelpilz- und Bakterienbefall zu schützenden, nichtionischen, kosmetischen und pharmazeutischen Zubereitungen noch weitere bekannte Konservierungsmittel, wie Dehydracetsäure, phenolische Konservierungsmittel, wie p-Hydroxybenzoesäureester, enthalten.2. The use of alkyl esters of sorbic acid according to claim 1, characterized characterized that the non-ionic, non-ionic, cosmetic and pharmaceutical preparations and other known preservatives, such as dehydroacetic acid, phenolic preservatives such as p-hydroxybenzoic acid ester, contain.
DED35559A 1961-03-04 1961-03-04 Process for the preservation of nonionic, cosmetic and pharmaceutical emulsions Pending DE1139610B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DED35559A DE1139610B (en) 1961-03-04 1961-03-04 Process for the preservation of nonionic, cosmetic and pharmaceutical emulsions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DED35559A DE1139610B (en) 1961-03-04 1961-03-04 Process for the preservation of nonionic, cosmetic and pharmaceutical emulsions

Publications (1)

Publication Number Publication Date
DE1139610B true DE1139610B (en) 1962-11-15

Family

ID=7042690

Family Applications (1)

Application Number Title Priority Date Filing Date
DED35559A Pending DE1139610B (en) 1961-03-04 1961-03-04 Process for the preservation of nonionic, cosmetic and pharmaceutical emulsions

Country Status (1)

Country Link
DE (1) DE1139610B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021239A1 (en) * 1991-06-04 1992-12-10 Ecolab Inc. Blended carboxylic acid sanitizer
US6302968B1 (en) 1994-04-19 2001-10-16 Ecolab Inc. Precarboxylic acid rinse method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021239A1 (en) * 1991-06-04 1992-12-10 Ecolab Inc. Blended carboxylic acid sanitizer
US6302968B1 (en) 1994-04-19 2001-10-16 Ecolab Inc. Precarboxylic acid rinse method

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