DE112007003185A5 - Risikostratifizierung des akuten Koronarsyndroms mittels Fragmenten / Teilpeptiden des proVasopressins, insbesondere Copeptin oder Neurophysin II - Google Patents
Risikostratifizierung des akuten Koronarsyndroms mittels Fragmenten / Teilpeptiden des proVasopressins, insbesondere Copeptin oder Neurophysin II Download PDFInfo
- Publication number
- DE112007003185A5 DE112007003185A5 DE112007003185T DE112007003185T DE112007003185A5 DE 112007003185 A5 DE112007003185 A5 DE 112007003185A5 DE 112007003185 T DE112007003185 T DE 112007003185T DE 112007003185 T DE112007003185 T DE 112007003185T DE 112007003185 A5 DE112007003185 A5 DE 112007003185A5
- Authority
- DE
- Germany
- Prior art keywords
- provasopressin
- neurophysin
- fragments
- acute coronary
- coronary syndrome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2410/00—Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids
- G01N2410/04—Oxytocins; Vasopressins; Related peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE200610050497 DE102006050497A1 (de) | 2006-10-26 | 2006-10-26 | Risikostratifizierung des akuten Koronarsyndroms mittels Fragmenten / Teilpeptiden des proVasopressins, insbesondere Copeptin oder Neurophysin II |
| DE102006050497.6 | 2006-10-26 | ||
| DE102006057409.5 | 2006-12-04 | ||
| DE200610057409 DE102006057409A1 (de) | 2006-12-04 | 2006-12-04 | Risikostratifizierung des akuten Koronarsyndroms mittels Fragmenten / Teilpeptiden des proVasopressins, insbesondere Copeptin oder Neurophysin II |
| PCT/DE2007/001928 WO2008049422A2 (de) | 2006-10-26 | 2007-10-26 | Risikostratifizierung des akuten koronarsyndroms mittels fragmenten / teilpeptiden des provasopressins, insbesondere copeptin oder neurophysin ii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE112007003185A5 true DE112007003185A5 (de) | 2009-10-01 |
Family
ID=39276269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE112007003185T Withdrawn DE112007003185A5 (de) | 2006-10-26 | 2007-10-26 | Risikostratifizierung des akuten Koronarsyndroms mittels Fragmenten / Teilpeptiden des proVasopressins, insbesondere Copeptin oder Neurophysin II |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US8501485B2 (enExample) |
| EP (1) | EP2084543B1 (enExample) |
| JP (2) | JP5320294B2 (enExample) |
| DE (1) | DE112007003185A5 (enExample) |
| DK (1) | DK2084543T3 (enExample) |
| ES (1) | ES2652027T3 (enExample) |
| PL (1) | PL2084543T3 (enExample) |
| WO (1) | WO2008049422A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140046407A1 (en) * | 2001-08-31 | 2014-02-13 | Bio Control Medical (B.C.M.) Ltd. | Nerve stimulation techniques |
| EP1628136A1 (en) * | 2004-08-19 | 2006-02-22 | B.R.A.H.M.S. Aktiengesellschaft | Method of diagnosis of disease using copeptin |
| WO2007121495A2 (en) * | 2006-04-24 | 2007-11-01 | Medizinische Universität Wien | Method for diagnosing cardiovascular diseases |
| DE112007003185A5 (de) * | 2006-10-26 | 2009-10-01 | Brahms Aktiengesellschaft | Risikostratifizierung des akuten Koronarsyndroms mittels Fragmenten / Teilpeptiden des proVasopressins, insbesondere Copeptin oder Neurophysin II |
| DE102006058266A1 (de) * | 2006-12-08 | 2008-06-12 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung von Herzinsuffizienz mittels Neurophysin |
| DE102007009751A1 (de) | 2007-02-28 | 2008-09-04 | B.R.A.H.M.S Aktiengesellschaft | Verfahren zur selektiven Bestimmung von Procalcitonin 1-116 für diagnostische Zwecke sowie Antikörper und Kits zur Durchführung eines solchen Verfahrens |
| ES2724478T3 (es) | 2008-10-24 | 2019-09-11 | Brahms Gmbh | Pronóstico y evaluación del riesgo en pacientes con accidente cerebrovascular determinando el nivel de péptidos marcadores |
| CN102317788A (zh) * | 2008-10-31 | 2012-01-11 | B.R.A.H.M.S有限公司 | 用作糖尿病预测生物标志物的精氨酸加压素激素原 |
| DK2427764T3 (en) * | 2009-05-05 | 2017-09-11 | Brahms Gmbh | VASOACTIVE HORMON-BASED STRATIFICATION OF PATIENTS SUFFERING OF DISEASES RELATED TO ENDOTELIAL FUNCTION / DYSFUNCTION |
| RU2618437C2 (ru) * | 2010-11-01 | 2017-05-03 | Б.Р.А.Х.М.С Гмбх | Оценка прогноза и риска пациентов с неспецифическими жалобами |
| EP2533052A1 (en) * | 2011-06-07 | 2012-12-12 | B.R.A.H.M.S GmbH | Diagnostic use of proSomatostatin |
| JP6403572B2 (ja) * | 2011-09-08 | 2018-10-10 | ネクサス・ディーエックス・インコーポレイテッドＮｅｘｕｓ Ｄｘ， Ｉｎｃ． | マルチレベル分析物アッセイ |
| EP4574024A3 (en) | 2016-02-01 | 2025-10-08 | Prevencio, Inc. | Diagnostic and prognostic methods for cardiovascular diseases and events |
| US11446009B2 (en) | 2018-12-11 | 2022-09-20 | Eko.Ai Pte. Ltd. | Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images |
| US12001939B2 (en) | 2018-12-11 | 2024-06-04 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views |
| US12322100B2 (en) | 2018-12-11 | 2025-06-03 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity |
| US11931207B2 (en) | 2018-12-11 | 2024-03-19 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device |
| US12400762B2 (en) | 2018-12-11 | 2025-08-26 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy |
| KR102318236B1 (ko) * | 2020-02-18 | 2021-10-26 | 한림대학교 산학협력단 | 혈중 코펩틴의 농도를 이용한 지연성 뇌허혈 진단 방법 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9305142D0 (en) * | 1993-03-12 | 1993-04-28 | Medinnova Sf | Method |
| DE60233301D1 (de) | 2001-05-04 | 2009-09-24 | Biosite Inc | Diagnostische marker für akute herzerkrankungen und verfahren des gebrauchs |
| MXPA03004105A (es) | 2002-05-14 | 2004-10-15 | Hoffmann La Roche | Elaboracion de una prognosis en casos de enfermedad cardiaca usando una combinacion de marcadores. |
| WO2004006860A2 (en) | 2002-07-16 | 2004-01-22 | Woomera Therapeutics, Inc. | Compositions and uses thereof for identifying and targeting provasopressin-expressing cancer cells |
| CA2485722A1 (en) * | 2003-10-22 | 2005-04-22 | Paul Lehmann | Soluble transferrin receptor |
| EP1530047A1 (en) * | 2003-11-07 | 2005-05-11 | Roche Diagnostics GmbH | Proximal markers of arterial thrombosis and inflammation for risk stratification of coronary heart disease |
| EP1628136A1 (en) * | 2004-08-19 | 2006-02-22 | B.R.A.H.M.S. Aktiengesellschaft | Method of diagnosis of disease using copeptin |
| DE102004051847B4 (de) * | 2004-10-25 | 2008-09-18 | Dade Behring Marburg Gmbh | Verhältnis von PIGF und Flt-1 als prognostischer Parameter bei kardio-vaskulären Erkrankungen |
| EP2924440A3 (en) * | 2006-06-07 | 2016-03-09 | Health Diagnostic Laboratory, Inc. | Markers associated with arteriovascular events and methods of use thereof |
| DE112007003185A5 (de) * | 2006-10-26 | 2009-10-01 | Brahms Aktiengesellschaft | Risikostratifizierung des akuten Koronarsyndroms mittels Fragmenten / Teilpeptiden des proVasopressins, insbesondere Copeptin oder Neurophysin II |
| DE102006053442A1 (de) * | 2006-11-12 | 2008-05-15 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung von Infektionen und chronischen Erkrankungen der Atemwege und Lunge mittels proVasopressin, insbesondere Copeptin oder Neurophysin II |
| DE102006058266A1 (de) * | 2006-12-08 | 2008-06-12 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung von Herzinsuffizienz mittels Neurophysin |
| DE102007021443A1 (de) * | 2007-05-08 | 2008-11-13 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung mittels NT-proET-1 |
| EP2148203A1 (en) * | 2008-07-23 | 2010-01-27 | BRAHMS Aktiengesellschaft | Azurophilic granule proteases as markers in cardiological diseases |
| ES2724478T3 (es) * | 2008-10-24 | 2019-09-11 | Brahms Gmbh | Pronóstico y evaluación del riesgo en pacientes con accidente cerebrovascular determinando el nivel de péptidos marcadores |
-
2007
- 2007-10-26 DE DE112007003185T patent/DE112007003185A5/de not_active Withdrawn
- 2007-10-26 EP EP07846265.2A patent/EP2084543B1/de active Active
- 2007-10-26 JP JP2009533659A patent/JP5320294B2/ja active Active
- 2007-10-26 PL PL07846265T patent/PL2084543T3/pl unknown
- 2007-10-26 ES ES07846265.2T patent/ES2652027T3/es active Active
- 2007-10-26 DK DK07846265.2T patent/DK2084543T3/en active
- 2007-10-26 US US12/447,105 patent/US8501485B2/en active Active
- 2007-10-26 WO PCT/DE2007/001928 patent/WO2008049422A2/de not_active Ceased
-
2013
- 2013-04-03 JP JP2013077587A patent/JP2013178249A/ja active Pending
- 2013-07-25 US US13/951,084 patent/US9261517B2/en active Active
-
2016
- 2016-01-21 US US15/003,734 patent/US10254289B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US8501485B2 (en) | 2013-08-06 |
| US9261517B2 (en) | 2016-02-16 |
| EP2084543B1 (de) | 2017-10-18 |
| US10254289B2 (en) | 2019-04-09 |
| WO2008049422A2 (de) | 2008-05-02 |
| US20130344513A1 (en) | 2013-12-26 |
| JP5320294B2 (ja) | 2013-10-23 |
| PL2084543T3 (pl) | 2018-04-30 |
| DK2084543T3 (en) | 2018-01-22 |
| US20160131660A1 (en) | 2016-05-12 |
| JP2013178249A (ja) | 2013-09-09 |
| WO2008049422A3 (de) | 2009-01-15 |
| JP2010507786A (ja) | 2010-03-11 |
| EP2084543A2 (de) | 2009-08-05 |
| US20100028921A1 (en) | 2010-02-04 |
| HK1137808A1 (en) | 2010-08-06 |
| ES2652027T3 (es) | 2018-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8181 | Inventor (new situation) |
Inventor name: MORGENTHALER, NILS, DR., 13503 BERLIN, DE Inventor name: PAPASSOTIRIOU, JANA, DR., 14163 BERLIN, DE Inventor name: STRUCK, JOACHIM, DR., 13465 BERLIN, DE Inventor name: LEONG, LOKE NG, LEICESTER, GB Inventor name: BERGMANN, ANDREAS, DR., 12351 BERLIN, DE |
|
| R012 | Request for examination validly filed | ||
| R082 | Change of representative |
Representative=s name: SIMANDI, CLAUS, DIPL.-CHEM., DE |
|
| R081 | Change of applicant/patentee |
Owner name: B.R.A.H.M.S GMBH, DE Free format text: FORMER OWNER: BRAHMS AKTIENGESELLSCHAFT, 16761 HENNIGSDORF, DE Effective date: 20140714 |
|
| R082 | Change of representative |
Representative=s name: SIMANDI, CLAUS, DIPL.-CHEM., DE Effective date: 20140714 |
|
| R012 | Request for examination validly filed |
Effective date: 20140711 |
|
| R082 | Change of representative | ||
| R119 | Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee |