DE10231297A1 - Nukleotidsequenzen coryneformer Bakterien codierend für an der Biosynthese von L-Serin beteiligte Proteine sowie Verfahren zur Herstellung von L-Serin - Google Patents

Nukleotidsequenzen coryneformer Bakterien codierend für an der Biosynthese von L-Serin beteiligte Proteine sowie Verfahren zur Herstellung von L-Serin Download PDF

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Publication number
DE10231297A1
DE10231297A1 DE10231297A DE10231297A DE10231297A1 DE 10231297 A1 DE10231297 A1 DE 10231297A1 DE 10231297 A DE10231297 A DE 10231297A DE 10231297 A DE10231297 A DE 10231297A DE 10231297 A1 DE10231297 A1 DE 10231297A1
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DE
Germany
Prior art keywords
serine
deregulated
phosphoglycerate dehydrogenase
seq
microorganism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10231297A
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German (de)
English (en)
Inventor
Petra Dr. Peters Wendisch
Roman Netzer
Lothar Dr. Eggeling
Hermann Prof. Dr. Sahm
Robert Dr. Faurie
Birgit Dr. Klaßen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forschungszentrum Juelich GmbH
Amino GmbH
Original Assignee
Forschungszentrum Juelich GmbH
Amino GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungszentrum Juelich GmbH, Amino GmbH filed Critical Forschungszentrum Juelich GmbH
Priority to DE10231297A priority Critical patent/DE10231297A1/de
Priority to PCT/DE2003/002290 priority patent/WO2004007705A1/de
Priority to JP2004520314A priority patent/JP2006524032A/ja
Priority to MXPA05000527A priority patent/MXPA05000527A/es
Priority to US10/520,999 priority patent/US7732176B2/en
Priority to BR0312374-0A priority patent/BR0312374A/pt
Priority to EP03763598A priority patent/EP1520013B1/de
Priority to DE50313042T priority patent/DE50313042D1/de
Priority to AT03763598T priority patent/ATE479745T1/de
Priority to KR1020057000470A priority patent/KR20060015439A/ko
Priority to DK03763598.4T priority patent/DK1520013T3/da
Publication of DE10231297A1 publication Critical patent/DE10231297A1/de
Priority to ZA200501158A priority patent/ZA200501158B/en
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01095—Phosphoglycerate dehydrogenase (1.1.1.95)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE10231297A 2002-07-10 2002-07-10 Nukleotidsequenzen coryneformer Bakterien codierend für an der Biosynthese von L-Serin beteiligte Proteine sowie Verfahren zur Herstellung von L-Serin Withdrawn DE10231297A1 (de)

Priority Applications (12)

Application Number Priority Date Filing Date Title
DE10231297A DE10231297A1 (de) 2002-07-10 2002-07-10 Nukleotidsequenzen coryneformer Bakterien codierend für an der Biosynthese von L-Serin beteiligte Proteine sowie Verfahren zur Herstellung von L-Serin
BR0312374-0A BR0312374A (pt) 2002-07-10 2003-07-08 Sequências de nucleotìdeos codificando fosfoglicerato-desidrogenases desreguladas de bactérias corineformes e processo para a preparação de l-serina
JP2004520314A JP2006524032A (ja) 2002-07-10 2003-07-08 コリネ型バクテリアの脱調節されたホスホグリセラート−デヒドロゲナーゼをコードするヌクレオチド配列並びにｌ−セリンの製造方法
MXPA05000527A MXPA05000527A (es) 2002-07-10 2003-07-08 Secuencias nucleotidas que codifican a las deshidrogenasas de fosfoglicerato desregularizadas de bacterias corineformes y procedimiento para la produccion de l-serina.
US10/520,999 US7732176B2 (en) 2002-07-10 2003-07-08 Nucleotide sequences that encode deregulated phosphoglycerate dehydrogenases of coryneform bacteria and method for producing L-serine
PCT/DE2003/002290 WO2004007705A1 (de) 2002-07-10 2003-07-08 Nukleotidsequenzen codierend für deregulierte phosphoglycerat-dehydrogenasen coryneformer bakterien sowie verfahren zur herstellung von l-serin
EP03763598A EP1520013B1 (de) 2002-07-10 2003-07-08 Nukleotidsequenzen codierend für deregulierte phosphoglycerat-dehydrogenasen coryneformer bakterien sowie verfahren zur herstellung von l-serin
DE50313042T DE50313042D1 (de) 2002-07-10 2003-07-08 Nukleotidsequenzen codierend für deregulierte phosphoglycerat-dehydrogenasen coryneformer bakterien sowie verfahren zur herstellung von l-serin
AT03763598T ATE479745T1 (de) 2002-07-10 2003-07-08 Nukleotidsequenzen codierend für deregulierte phosphoglycerat-dehydrogenasen coryneformer bakterien sowie verfahren zur herstellung von l- serin
KR1020057000470A KR20060015439A (ko) 2002-07-10 2003-07-08 코리네형 박테리아의 탈조절 포스포글리세레이트디히드로게나제를 암호화하는 뉴클레오티드 서열 및ｌ-세린의 제조 방법
DK03763598.4T DK1520013T3 (da) 2002-07-10 2003-07-08 Nukleotidsekvenser der koder for deregulerede phosphoglycerat-dehydrogenaser i coryneforme bakterier, samt fremgangsmåde til fremstilling af L-serin
ZA200501158A ZA200501158B (en) 2002-07-10 2005-02-09 Nucleotide sequences that encode deregulated phosphoglycerate dehydrogenases of coryneform bacteria and method for producing L-serine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10231297A DE10231297A1 (de) 2002-07-10 2002-07-10 Nukleotidsequenzen coryneformer Bakterien codierend für an der Biosynthese von L-Serin beteiligte Proteine sowie Verfahren zur Herstellung von L-Serin

Publications (1)

Publication Number Publication Date
DE10231297A1 true DE10231297A1 (de) 2004-02-05

Family

ID=30009893

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10231297A Withdrawn DE10231297A1 (de) 2002-07-10 2002-07-10 Nukleotidsequenzen coryneformer Bakterien codierend für an der Biosynthese von L-Serin beteiligte Proteine sowie Verfahren zur Herstellung von L-Serin
DE50313042T Expired - Lifetime DE50313042D1 (de) 2002-07-10 2003-07-08 Nukleotidsequenzen codierend für deregulierte phosphoglycerat-dehydrogenasen coryneformer bakterien sowie verfahren zur herstellung von l-serin

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE50313042T Expired - Lifetime DE50313042D1 (de) 2002-07-10 2003-07-08 Nukleotidsequenzen codierend für deregulierte phosphoglycerat-dehydrogenasen coryneformer bakterien sowie verfahren zur herstellung von l-serin

Country Status (11)

Country Link
US (1) US7732176B2 (enExample)
EP (1) EP1520013B1 (enExample)
JP (1) JP2006524032A (enExample)
KR (1) KR20060015439A (enExample)
AT (1) ATE479745T1 (enExample)
BR (1) BR0312374A (enExample)
DE (2) DE10231297A1 (enExample)
DK (1) DK1520013T3 (enExample)
MX (1) MXPA05000527A (enExample)
WO (1) WO2004007705A1 (enExample)
ZA (1) ZA200501158B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007144018A1 (en) * 2006-06-12 2007-12-21 Metabolic Explorer Ethanolamine production by fermentation
US20130316416A1 (en) 2012-02-23 2013-11-28 Massachusetts Institute Of Technology Engineering microbes and metabolic pathways for the production of ethylene glycol
CN114134185B (zh) * 2021-10-30 2024-06-21 新泰市佳禾生物科技有限公司 一种发酵生产l-丝氨酸的方法
JP2025535809A (ja) * 2022-10-20 2025-10-28 シスビオ エーピーエス Ｌ－セリンを産生する遺伝子組換え宿主細胞

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0931833A2 (en) * 1998-01-12 1999-07-28 Ajinomoto Co., Inc. Method of producing L-serine fermentation
EP0943687A2 (en) * 1998-01-12 1999-09-22 Ajinomoto Co., Inc. Method of producing L-serine by fermentation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3078312B2 (ja) * 1990-11-22 2000-08-21 協和醗酵工業株式会社 物質の製造法
DE4232468A1 (de) * 1992-09-28 1994-03-31 Consortium Elektrochem Ind Mikroorganismen für die Produktion von Tryptophan und Verfahren zu ihrer Herstellung

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0931833A2 (en) * 1998-01-12 1999-07-28 Ajinomoto Co., Inc. Method of producing L-serine fermentation
EP0943687A2 (en) * 1998-01-12 1999-09-22 Ajinomoto Co., Inc. Method of producing L-serine by fermentation

Also Published As

Publication number Publication date
WO2004007705A1 (de) 2004-01-22
EP1520013A1 (de) 2005-04-06
MXPA05000527A (es) 2005-09-30
ZA200501158B (en) 2007-04-25
JP2006524032A (ja) 2006-10-26
US20060106207A1 (en) 2006-05-18
KR20060015439A (ko) 2006-02-17
DE50313042D1 (de) 2010-10-14
US7732176B2 (en) 2010-06-08
BR0312374A (pt) 2005-04-12
DK1520013T3 (da) 2010-12-20
ATE479745T1 (de) 2010-09-15
EP1520013B1 (de) 2010-09-01
WO2004007705A9 (de) 2005-03-31

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R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee

Effective date: 20120201