MXPA05000527A - Secuencias nucleotidas que codifican a las deshidrogenasas de fosfoglicerato desregularizadas de bacterias corineformes y procedimiento para la produccion de l-serina. - Google Patents

Secuencias nucleotidas que codifican a las deshidrogenasas de fosfoglicerato desregularizadas de bacterias corineformes y procedimiento para la produccion de l-serina.

Info

Publication number
MXPA05000527A
MXPA05000527A MXPA05000527A MXPA05000527A MXPA05000527A MX PA05000527 A MXPA05000527 A MX PA05000527A MX PA05000527 A MXPA05000527 A MX PA05000527A MX PA05000527 A MXPA05000527 A MX PA05000527A MX PA05000527 A MXPA05000527 A MX PA05000527A
Authority
MX
Mexico
Prior art keywords
serine
producing
nucleotide sequences
coryneform bacteria
phosphoglycerate
Prior art date
Application number
MXPA05000527A
Other languages
English (en)
Inventor
Birgit Klassen
Original Assignee
Forschungszentrum Juelich Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungszentrum Juelich Gmbh filed Critical Forschungszentrum Juelich Gmbh
Publication of MXPA05000527A publication Critical patent/MXPA05000527A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01095—Phosphoglycerate dehydrogenase (1.1.1.95)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La invencion se refiere a secuencias de nucleotidos de bacterias corineformes que codifican a las proteinas que participan en la biosintesis de la L-serina asi como a un procedimiento para la produccion de L-serina. Por medio de la delecion de cuando menos 79 aminoacidos en la terminal C de la secuencia serA tipo silvestre puede producirse una dihidrogenasa de 3-fosfoglicerato que tiene una reducida retroinhibicion por L-serina frente a la secuencia de tipo silvestre.
MXPA05000527A 2002-07-10 2003-07-08 Secuencias nucleotidas que codifican a las deshidrogenasas de fosfoglicerato desregularizadas de bacterias corineformes y procedimiento para la produccion de l-serina. MXPA05000527A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10231297A DE10231297A1 (de) 2002-07-10 2002-07-10 Nukleotidsequenzen coryneformer Bakterien codierend für an der Biosynthese von L-Serin beteiligte Proteine sowie Verfahren zur Herstellung von L-Serin
PCT/DE2003/002290 WO2004007705A1 (de) 2002-07-10 2003-07-08 Nukleotidsequenzen codierend für deregulierte phosphoglycerat-dehydrogenasen coryneformer bakterien sowie verfahren zur herstellung von l-serin

Publications (1)

Publication Number Publication Date
MXPA05000527A true MXPA05000527A (es) 2005-09-30

Family

ID=30009893

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05000527A MXPA05000527A (es) 2002-07-10 2003-07-08 Secuencias nucleotidas que codifican a las deshidrogenasas de fosfoglicerato desregularizadas de bacterias corineformes y procedimiento para la produccion de l-serina.

Country Status (11)

Country Link
US (1) US7732176B2 (es)
EP (1) EP1520013B1 (es)
JP (1) JP2006524032A (es)
KR (1) KR20060015439A (es)
AT (1) ATE479745T1 (es)
BR (1) BR0312374A (es)
DE (2) DE10231297A1 (es)
DK (1) DK1520013T3 (es)
MX (1) MXPA05000527A (es)
WO (1) WO2004007705A1 (es)
ZA (1) ZA200501158B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007144018A1 (en) * 2006-06-12 2007-12-21 Metabolic Explorer Ethanolamine production by fermentation
US20130316416A1 (en) * 2012-02-23 2013-11-28 Massachusetts Institute Of Technology Engineering microbes and metabolic pathways for the production of ethylene glycol
CN114134185B (zh) * 2021-10-30 2024-06-21 新泰市佳禾生物科技有限公司 一种发酵生产l-丝氨酸的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3078312B2 (ja) 1990-11-22 2000-08-21 協和醗酵工業株式会社 物質の製造法
DE4232468A1 (de) * 1992-09-28 1994-03-31 Consortium Elektrochem Ind Mikroorganismen für die Produktion von Tryptophan und Verfahren zu ihrer Herstellung
JP4066543B2 (ja) * 1998-01-12 2008-03-26 味の素株式会社 発酵法によるｌ−セリンの製造法
JP3997631B2 (ja) * 1998-01-12 2007-10-24 味の素株式会社 発酵法によるｌ−セリンの製造法

Also Published As

Publication number Publication date
ZA200501158B (en) 2007-04-25
EP1520013B1 (de) 2010-09-01
DE10231297A1 (de) 2004-02-05
JP2006524032A (ja) 2006-10-26
WO2004007705A9 (de) 2005-03-31
KR20060015439A (ko) 2006-02-17
BR0312374A (pt) 2005-04-12
US7732176B2 (en) 2010-06-08
WO2004007705A1 (de) 2004-01-22
DK1520013T3 (da) 2010-12-20
EP1520013A1 (de) 2005-04-06
US20060106207A1 (en) 2006-05-18
ATE479745T1 (de) 2010-09-15
DE50313042D1 (de) 2010-10-14

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Legal Events

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