DE102022101354A1 - Traditional Chinese medicine - Google Patents

Abstract

The invention discloses a traditional Chinese medicine for treating intercostal neuralgia, which is made of medicinal materials in the following weight ratio: 10 parts apricot kernel, 10 parts fritillaria, 12 parts stemona root, 8 parts loquat, 8 parts roasted fructus aurantii, and 8 parts turmeric. The clinical experiment shows that the invention achieves the remarkable effect of treating intercostal neuralgia by selecting appropriate medicinal materials and their ratio, and is safe and non-toxic.

Description

TECHNICAL AREA

The invention relates to a traditional Chinese medicine, and more particularly relates to a traditional Chinese medicine for treating intercostal neuralgia and a method for the production thereof.

BACKGROUND

Intercostal neuralgia refers to a disease with unilateral or bilateral flank pain as the main clinical presentation, which belongs to the flank pain category in traditional Chinese medicine. The treatment of traditional Chinese medicine is mainly based on syndrome differentiation from the perspective of liver qi stagnation, qi stagnation and blood congestion, liver yin deficiency, and so on, to calm the liver and regulate qi, stimulate blood circulation and eliminate congestion, nourish blood and yin, and soothe the liver. For the treatment of intercostal neuralgia, there is still a lack of traditional Chinese medicines and western medicines with well-known safety and efficacy.

SUMMARY

The invention aims to provide a traditional Chinese medicine for treating intercostal neuralgia and a method of manufacturing the same. Based on the selection of an appropriate traditional Chinese medicine and its ratio, it can achieve a significant supportive effect on the recovery of intercostal neuralgia patients, and is safe and non-toxic.

8-10 Teile Fritillaria

10-12 Teile Stemonawurzel

6-8 Teile Loquat

6-8 Teile gerösteter Fructus aurantii

und 6-8 Teile Kurkuma

In order to achieve the aforesaid object, the invention adopts the following technical solution: a traditional Chinese medicine for treating intercostal neuralgia, which is made of medicinal materials with the following weight ratio: 8-10 parts apricot kernel

8-10 parts Fritillaria

10-12 parts stemona root

6-8 parts loquat

6-8 parts roasted Fructus aurantii

and 6-8 parts turmeric

In a preferred embodiment, it is made of medicinal materials in the following weight ratio: 10 parts apricot kernel, 10 parts fritillaria, 12 parts stemona root, 8 parts loquat, 8 parts roasted fructus aurantii, and 8 parts turmeric.

In a preferred embodiment, it is made of medicinal materials in the following weight ratio: 9 parts apricot kernel, 9 parts fritillaria, 12 parts stemona root, 8 parts loquat, 8 parts roasted fructus aurantii, and 8 parts turmeric.

In a preferred embodiment, it is made of medicinal materials in the following weight ratio: 10 parts apricot kernel, 10 parts fritillaria, 10 parts stemona root, 6 parts loquat, 6 parts roasted fructus aurantii, and 8 parts turmeric.

In a preferred embodiment, it is made of medicinal materials in the following weight ratio: 9 parts apricot kernel, 10 parts fritillaria, 12 parts stemona root, 8 parts loquat, 8 parts roasted fructus aurantii, and 6 parts turmeric.

A method of preparing the traditional Chinese medicine for treating intercostal neuralgia includes the following steps: (1) placing apricot kernel, fritillaria, stemona root, loquat and turmeric in a container, adding 8-10 times the amount of distilled water, soaking for 5-6 hours, boiling for 3-4 hours and extracting; Adding 6-8 times the amount of distilled water again, boiling for 2-3 hours and extracting; lastly adding 4-6 times the amount of distilled water, heating and boiling for 1-2 hours and extracting; combining the three extracts and filtering to obtain and provide the filtrate; (2) Grinding roasted Fructus aurantii into fine powder and adding it into the container, adding hard alcohol and adding some honey, stirring evenly, sealing the container, and heating by water for 15-25 minutes to get a paste and ready; and (3) mixing the filtrate and the paste prepared in the above steps (1) to (2) and fabricating capsules using modern advanced pharmaceutical technology, thereby obtaining the formulation of the traditional Chinese medicine of the invention.

1. 1. Die Formulierung des traditionellen chinesischen Medikaments der Erfindung weist eine hohe Heilungsrate bei der Behandlung von Interkostalneuralgie auf, ist sicher und ungiftig und kann damit zusammenhängende Komplikationen verhindern. Die Kompatibilität der medizinischen Materialien ist exakt, was nicht nur die durch die medizinische Kompatibilität geschaffene Synergie vollständig ausnutzt, sondern auch die gegenseitige Beschränkung medizinischer Wirkungen vermeidet, welche die ursprüngliche Wirksamkeit aufhebt oder schwächt. Der Auswahl von Anwendungen medizinischer Kompatibilität, welche die Intensität oder toxische oder Nebenwirkungen von Medikamenten verringern oder beseitigen können, wird mehr Aufmerksamkeit gewidmet, um so durch medizinische Kompatibilität verursachte toxische Reaktionen oder starke Nebenwirkungen entschieden zu vermeiden. Durch wissenschaftliche Kompatibilität im Fall komplexer und sich schnell verändernder Bedingungen kann die Erfindung nicht nur wirksam eine sinnvolle Behandlung zur Beseitigung der Krankheit organisieren und umsetzen, sondern weist auch eine gute vorbeugende Wirkung bei der Verhinderung der Krankheitsausbreitung und des innerlichen Befalls von Organen auf, was in der klinischen Anwendung von großem Wert ist.
2. 2. Die Formulierung des traditionellen chinesischen Medikaments der Erfindung wird aus qualitativ hochwertigem traditionellen chinesischen Medikament hergestellt, die Kompatibilität des ausgewählten traditionellen chinesischen Medikaments ist geeignet, was mit der Forschungstheorie traditioneller chinesischer Medizin und moderner Medizin übereinstimmt, und wird unter Verwendung moderner pharmazeutischer Technologie hergestellt, was sicher, ungiftig und Nebenwirkungen ist, erfüllt den Zweck der Behandlung von sowohl Symptomen als auch Symptomen, und ist angemessen für klinische Anwendung.

Compared to the prior art, the invention has the following advantageous effects:

1. 1. The formulation of traditional Chinese medicine of the invention has a high cure rate in the treatment of intercostal neuralgia, is safe and non-toxic, and can prevent related complications. The compatibility of the medical materials is exact, which not only fully utilizes the synergy created by the medical compatibility, but also who also avoids the mutual restriction of medical effects that neutralize or weaken the original effectiveness. More attention is paid to the selection of applications of medical compatibility, which can reduce or eliminate the intensity or toxic or side effects of drugs, so as to decisively avoid toxic reactions or strong side effects caused by medical compatibility. With scientific compatibility in the case of complex and rapidly changing conditions, the invention can not only effectively organize and implement a reasonable treatment to eliminate the disease, but also has a good preventive effect in preventing the disease from spreading and infecting internal organs, which is of great value in clinical application.
2. 2. The formulation of the traditional Chinese medicine of the invention is made of high quality traditional Chinese medicine, the compatibility of the selected traditional Chinese medicine is suitable, which is in line with the research theory of traditional Chinese medicine and modern medicine, and is manufactured using modern pharmaceutical technology, which is safe, non-toxic and side effects, achieves the purpose of treating both symptoms and symptoms, and is reasonable for clinical use.

DETAILED DESCRIPTION

In order that the invention can be better understood and put into practice, the invention is explained in more detail below in connection with specific embodiments.

example 1

10 parts apricot kernel, 10 parts fritillaria, 12 parts stemona root, 8 parts loquat, 8 parts roasted fructus aurantii and 8 parts turmeric are weighed. The following steps include: (1) placing apricot kernel, fritillaria, stemona root, loquat and turmeric in a container, adding 8-10 times the amount of distilled water, soaking for 5-6 hours, boiling for 3-4 hours, and extracting; adding 6-8 times the amount of distilled water again, boiling for 2-3 hours, and extracting; lastly adding 4-6 times the amount of distilled water, heating and boiling for 1-2 hours, and extracting; combining the three extracts and filtering to obtain and provide the filtrate; (2) Grinding roasted Fructus aurantii into fine powder and adding it into the container, adding hard alcohol and adding some honey, stirring evenly, sealing the container, and heating by water for 15-25 minutes to get a paste and ready; and (3) mixing the filtrate and the paste prepared in the aforesaid steps (1) and (2) and fabricating capsules using modern advanced pharmaceutical technology, thereby obtaining the formulation of the traditional Chinese medicine of the invention.

Use and dosage: oral administration, twice a day, once in the morning and once in the evening, one capsule at a time, taken with warm boiled water after a meal.

example 2

Weigh 9 parts apricot kernel, 9 parts fritillaria, 10 parts stemona root, 6 parts loquat, 6 parts roasted fructus aurantii, and 8 parts turmeric.

The method of preparation, use and dosage of this example are similar to those of example 1.

Example 3

Weigh 9 parts apricot kernel, 10 parts fritillaria, 12 parts stemona root, 8 parts loquat, 8 parts roasted fructus aurantii, and 6 parts turmeric.

The method of preparation, use and dosage of this example are similar to those of example 1.

Clinical data:

1. Case selection

56 patients with intercostal neuralgia were selected for clinical observation. The clinical symptoms corresponded to the diagnostic and therapeutic criteria of intercostal neuralgia. The patients were randomly divided into treatment group and control group. There were 28 cases in the treatment group and 28 cases in the control group. The course of the disease and the severity of the symptoms in the treatment group and the control group were basically the same, with no significant difference and comparability.

2. Drug selection

The treatment group took the traditional Chinese medicine capsule prepared in Example 1 of the invention orally twice a day, once in the morning and once in the evening, one capsule each taken after the meal with warm boiled water; 5 days is one course of treatment, and the treatment lasts 1-2 courses.

The control group was treated with conventional western medicine, and the course of treatment was the same as that of the treatment group.

After two courses, the healing effects of both groups were compared, and all cases were followed up after 6 months.

3. Efficacy Criteria

1. (1) Cured: pain and accompanying symptoms have disappeared, and after half a year of follow-up, no recurrence occurred.
2. (2) Alleviated: The pain and accompanying symptoms were significantly alleviated after the treatment.
3. (3) Not cured: It is invalid if there is no change in pain and concomitant symptoms after treatment.

4. Result

In the treatment group which took the capsule of the traditional Chinese medicine in Example 1 of the invention, 21 cases were cured, 5 cases were alleviated, and 2 cases were not cured. The cure rate was 75% and the overall efficacy rate was 94.9%.

In the control group, 3 cases were cured, 17 cases were alleviated, and 8 cases were not cured. The cure rate was 10.7% and the overall efficacy rate was 71.4%.

The above results showed that the cure rate and overall efficacy rate of the treatment group were significantly higher than those of the control group.

Of course, the aforementioned embodiments are only examples to clearly explain the invention, not to limit the embodiments of the invention. Other forms of variables or changes may be made by those skilled in the art based on the above description. All the embodiments here can not be exhaustive, all obvious variables or changes, which are due to the technical solution of the invention, still fall within the scope of the present invention.

Claims (6)

A traditional Chinese drug for treating intercostal neuralgia, characterized by being made of medicinal materials with the following weight ratio: 8-10 parts apricot kernel, 8-10 parts fritillaria, 10-12 parts stemona root, 6-8 parts loquat, 6-8 parts roasted fructus aurantii, and 6-8 parts turmeric. Traditional Chinese drug used to treat intercostal neuralgia after claim 1 characterized in that it is made of medicinal materials with the following weight ratio: 10 parts apricot kernel, 10 parts fritillaria, 12 parts stemona root, 8 parts loquat, 8 parts roasted fructus aurantii, and 8 parts turmeric. Traditional Chinese drug used to treat intercostal neuralgia after claim 1 characterized in that it is made of medicinal materials with the following weight ratio: 9 parts apricot kernel, 9 parts fritillaria, 12 parts stemona root, 8 parts loquat, 8 parts roasted fructus aurantii, and 8 parts turmeric. Traditional Chinese drug used to treat intercostal neuralgia after claim 1 characterized in that it is made of medicinal materials with the following weight ratio: 10 parts apricot kernel, 10 parts fritillaria, 10 parts stemona root, 6 parts loquat, 6 parts roasted fructus aurantii, and 8 parts turmeric. Traditional Chinese drug used to treat intercostal neuralgia after claim 1 characterized in that it is made of medicinal materials with the following weight ratio: 9 parts apricot kernel, 10 parts fritillaria, 12 parts stemona root, 8 parts loquat, 8 parts roasted fructus aurantii, and 6 parts turmeric. A method of manufacturing a traditional Chinese medicine for treating intercostal neuralgia, characterized by comprising the following steps: (1) placing apricot kernel, fritillaria, stemona root, loquat and turmeric in a container, adding 8-10 times the amount of distilled water, soaking for 5-6 hours, boiling for 3-4 hours, and Extract; adding 6-8 times the amount of distilled water again, boiling for 2-3 hours, and extracting; lastly adding 4-6 times the amount of distilled water, heating and boiling for 1-2 hours, and extracting; combining the three extracts and filtering to obtain and provide the filtrate; (2) Grinding roasted Fructus aurantii into fine powder and adding it into the container, adding hard alcohol and adding some honey, stirring evenly, sealing the container, and heating by water for 15-25 minutes to get a paste and ready; and (3) mixing the filtrate and the paste prepared in the aforesaid steps (1) and (2) and fabricating capsules using modern advanced pharmaceutical technology, thereby obtaining the formulation of the traditional Chinese medicine of the invention.