DE102006058424A1 - Quantifizierung von Probeneigenschaften unter Nutzung von Kontrastverstärkung bei Sättigungstransfer - Google Patents

Quantifizierung von Probeneigenschaften unter Nutzung von Kontrastverstärkung bei Sättigungstransfer Download PDF

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Publication number
DE102006058424A1
DE102006058424A1 DE102006058424A DE102006058424A DE102006058424A1 DE 102006058424 A1 DE102006058424 A1 DE 102006058424A1 DE 102006058424 A DE102006058424 A DE 102006058424A DE 102006058424 A DE102006058424 A DE 102006058424A DE 102006058424 A1 DE102006058424 A1 DE 102006058424A1
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DE
Germany
Prior art keywords
cest
patient
magnetization
resonance
field strength
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102006058424A
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German (de)
English (en)
Inventor
Thomas W. Dixon
Ileana Hancu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Electric Co
Original Assignee
General Electric Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Electric Co filed Critical General Electric Co
Publication of DE102006058424A1 publication Critical patent/DE102006058424A1/de
Withdrawn legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4804—Spatially selective measurement of temperature or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5605—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by transferring coherence or polarization from a spin species to another, e.g. creating magnetization transfer contrast [MTC], polarization transfer using nuclear Overhauser enhancement [NOE]

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  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE102006058424A 2005-12-08 2006-12-08 Quantifizierung von Probeneigenschaften unter Nutzung von Kontrastverstärkung bei Sättigungstransfer Withdrawn DE102006058424A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/297,263 2005-12-08
US11/297,263 US7610077B2 (en) 2005-12-08 2005-12-08 Quantitation of sample properties using contrast enhancement from saturation transfer

Publications (1)

Publication Number Publication Date
DE102006058424A1 true DE102006058424A1 (de) 2007-07-19

Family

ID=38139589

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102006058424A Withdrawn DE102006058424A1 (de) 2005-12-08 2006-12-08 Quantifizierung von Probeneigenschaften unter Nutzung von Kontrastverstärkung bei Sättigungstransfer

Country Status (4)

Country Link
US (1) US7610077B2 (https=)
JP (1) JP5193460B2 (https=)
DE (1) DE102006058424A1 (https=)
NL (1) NL1033025C2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8463358B2 (en) * 2006-06-09 2013-06-11 Koninklijke Philips Electronics N.V. Elimination of contrast agent concentration dependency in MRI
US8536866B2 (en) * 2007-09-26 2013-09-17 The Johns Hopkins University Frequency referencing for chemical exchange saturation transfer (CEST) MRI
US8278925B2 (en) * 2008-03-26 2012-10-02 The General Hospital Corporation Method for relaxation-compensated fast multi-slice chemical exchange saturation transfer MRI
WO2009126289A2 (en) * 2008-04-09 2009-10-15 Beth Israel Deaconess Medical Center, Inc. Positive magnetic resonance imaging contrast methods and apparatus using chemical exchange saturation transfer
US8611981B2 (en) * 2008-08-26 2013-12-17 Bracco Imaging S.P.A. MRI-CEST diagnostic technique based on non-punctual analysis
US8686727B2 (en) * 2010-07-20 2014-04-01 The Trustees Of The University Of Pennsylvania CEST MRI methods for imaging of metabolites and the use of same as biomarkers
US9709511B2 (en) * 2011-11-28 2017-07-18 New York University Apparatus, system, method and computer-readable medium for isolating chemical exchange saturation transfer contrast from magnetization transfer asymmetry under two-frequency RF irradiation
US9335393B2 (en) 2012-09-13 2016-05-10 Siemens Medical Solutions Usa, Inc. MR parallel imaging system reducing imaging time
WO2014165719A1 (en) * 2013-04-05 2014-10-09 The Trustees Of The University Of Pennsylvania Non-invasive imaging of tissue redox state by mri
US10267881B2 (en) 2014-12-18 2019-04-23 The Johns Hopkins University Multi-echo parametric variation saturation (MePaVARS CEST imaging and other MR imaging
JP7038671B2 (ja) * 2016-06-08 2022-03-18 シーダーズ－サイナイ メディカル センター 定量的化学交換飽和移動（ｑＣＥＳＴ）を用いた非侵襲性のｐＨ依存的イメージング
CN111722167B (zh) * 2019-03-19 2021-07-30 浙江大学 化学交换饱和转移-磁共振成像cest-mri序列生成方法、装置及可读存储介质

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1178837A2 (en) * 1999-04-21 2002-02-13 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Method for enhancing contrast produced by mri
EP1331012A1 (en) * 2002-01-29 2003-07-30 BRACCO IMAGING S.p.A. Responsive paramagnetic MRI contrast agents
US8639542B2 (en) * 2002-06-27 2014-01-28 Siebel Systems, Inc. Method and apparatus to facilitate development of a customer-specific business process model
JP2008513533A (ja) * 2004-09-23 2008-05-01 ゲルベ Ｃｅｓｔイメージング用の造影剤封入システム
WO2006114765A2 (en) * 2005-04-26 2006-11-02 Koninklijke Philips Electronics N.V. Mri involving contrast agent with time modulated contrast enhancement
EP1889086B1 (en) * 2005-04-26 2010-01-13 Koninklijke Philips Electronics N.V. Method for using cest contrast agents in mri

Also Published As

Publication number Publication date
JP5193460B2 (ja) 2013-05-08
US7610077B2 (en) 2009-10-27
NL1033025C2 (nl) 2010-05-21
US20070134159A1 (en) 2007-06-14
JP2007152128A (ja) 2007-06-21
NL1033025A1 (nl) 2007-06-11

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Effective date: 20131031

R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee