JP5193460B2 - 飽和移転からのコントラスト強調を用いた試料特性の定量化 - Google Patents

飽和移転からのコントラスト強調を用いた試料特性の定量化 Download PDF

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Publication number
JP5193460B2
JP5193460B2 JP2006332426A JP2006332426A JP5193460B2 JP 5193460 B2 JP5193460 B2 JP 5193460B2 JP 2006332426 A JP2006332426 A JP 2006332426A JP 2006332426 A JP2006332426 A JP 2006332426A JP 5193460 B2 JP5193460 B2 JP 5193460B2
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Japan
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cest
resonance
magnetization
intensity
pulse
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JP2006332426A
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Japanese (ja)
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JP2007152128A5 (https=
JP2007152128A (ja
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ダブリュー・トーマス・ディクソン
イリーナ・ハンクー
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General Electric Co
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General Electric Co
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4804—Spatially selective measurement of temperature or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5605—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by transferring coherence or polarization from a spin species to another, e.g. creating magnetization transfer contrast [MTC], polarization transfer using nuclear Overhauser enhancement [NOE]

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  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2006332426A 2005-12-08 2006-12-08 飽和移転からのコントラスト強調を用いた試料特性の定量化 Expired - Fee Related JP5193460B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/297,263 2005-12-08
US11/297,263 US7610077B2 (en) 2005-12-08 2005-12-08 Quantitation of sample properties using contrast enhancement from saturation transfer

Publications (3)

Publication Number Publication Date
JP2007152128A JP2007152128A (ja) 2007-06-21
JP2007152128A5 JP2007152128A5 (https=) 2011-01-27
JP5193460B2 true JP5193460B2 (ja) 2013-05-08

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ID=38139589

Family Applications (1)

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JP2006332426A Expired - Fee Related JP5193460B2 (ja) 2005-12-08 2006-12-08 飽和移転からのコントラスト強調を用いた試料特性の定量化

Country Status (4)

Country Link
US (1) US7610077B2 (https=)
JP (1) JP5193460B2 (https=)
DE (1) DE102006058424A1 (https=)
NL (1) NL1033025C2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8463358B2 (en) * 2006-06-09 2013-06-11 Koninklijke Philips Electronics N.V. Elimination of contrast agent concentration dependency in MRI
US8536866B2 (en) * 2007-09-26 2013-09-17 The Johns Hopkins University Frequency referencing for chemical exchange saturation transfer (CEST) MRI
US8278925B2 (en) * 2008-03-26 2012-10-02 The General Hospital Corporation Method for relaxation-compensated fast multi-slice chemical exchange saturation transfer MRI
WO2009126289A2 (en) * 2008-04-09 2009-10-15 Beth Israel Deaconess Medical Center, Inc. Positive magnetic resonance imaging contrast methods and apparatus using chemical exchange saturation transfer
US8611981B2 (en) * 2008-08-26 2013-12-17 Bracco Imaging S.P.A. MRI-CEST diagnostic technique based on non-punctual analysis
US8686727B2 (en) * 2010-07-20 2014-04-01 The Trustees Of The University Of Pennsylvania CEST MRI methods for imaging of metabolites and the use of same as biomarkers
US9709511B2 (en) * 2011-11-28 2017-07-18 New York University Apparatus, system, method and computer-readable medium for isolating chemical exchange saturation transfer contrast from magnetization transfer asymmetry under two-frequency RF irradiation
US9335393B2 (en) 2012-09-13 2016-05-10 Siemens Medical Solutions Usa, Inc. MR parallel imaging system reducing imaging time
WO2014165719A1 (en) * 2013-04-05 2014-10-09 The Trustees Of The University Of Pennsylvania Non-invasive imaging of tissue redox state by mri
US10267881B2 (en) 2014-12-18 2019-04-23 The Johns Hopkins University Multi-echo parametric variation saturation (MePaVARS CEST imaging and other MR imaging
JP7038671B2 (ja) * 2016-06-08 2022-03-18 シーダーズ－サイナイ メディカル センター 定量的化学交換飽和移動（ｑＣＥＳＴ）を用いた非侵襲性のｐＨ依存的イメージング
CN111722167B (zh) * 2019-03-19 2021-07-30 浙江大学 化学交换饱和转移-磁共振成像cest-mri序列生成方法、装置及可读存储介质

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1178837A2 (en) * 1999-04-21 2002-02-13 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Method for enhancing contrast produced by mri
EP1331012A1 (en) * 2002-01-29 2003-07-30 BRACCO IMAGING S.p.A. Responsive paramagnetic MRI contrast agents
US8639542B2 (en) * 2002-06-27 2014-01-28 Siebel Systems, Inc. Method and apparatus to facilitate development of a customer-specific business process model
JP2008513533A (ja) * 2004-09-23 2008-05-01 ゲルベ Ｃｅｓｔイメージング用の造影剤封入システム
WO2006114765A2 (en) * 2005-04-26 2006-11-02 Koninklijke Philips Electronics N.V. Mri involving contrast agent with time modulated contrast enhancement
EP1889086B1 (en) * 2005-04-26 2010-01-13 Koninklijke Philips Electronics N.V. Method for using cest contrast agents in mri

Also Published As

Publication number Publication date
DE102006058424A1 (de) 2007-07-19
US7610077B2 (en) 2009-10-27
NL1033025C2 (nl) 2010-05-21
US20070134159A1 (en) 2007-06-14
JP2007152128A (ja) 2007-06-21
NL1033025A1 (nl) 2007-06-11

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