DE10121215A1 - Dihydro-imidazo[4,5-e]indol- und 7H-Pyrrolo[3,2-f]chinoxalin Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden - Google Patents
Dihydro-imidazo[4,5-e]indol- und 7H-Pyrrolo[3,2-f]chinoxalin Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge LigandenInfo
- Publication number
- DE10121215A1 DE10121215A1 DE10121215A DE10121215A DE10121215A1 DE 10121215 A1 DE10121215 A1 DE 10121215A1 DE 10121215 A DE10121215 A DE 10121215A DE 10121215 A DE10121215 A DE 10121215A DE 10121215 A1 DE10121215 A1 DE 10121215A1
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- Germany
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- formula
- compounds
- solvates
- oct
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Landscapes
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Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10121215A DE10121215A1 (de) | 2001-04-30 | 2001-04-30 | Dihydro-imidazo[4,5-e]indol- und 7H-Pyrrolo[3,2-f]chinoxalin Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden |
| US10/476,234 US7279496B2 (en) | 2001-04-30 | 2002-03-30 | Dihydroimidazo[4,5-e]indole and 7h-pyrrolo[3,2-f]quinoxaline derivatives as nicotinic acetylcholine receptor ligands and/or serotonergic ligands |
| JP2002585441A JP4593879B2 (ja) | 2001-04-30 | 2002-03-30 | ニコチン性アセチルコリンレセプターリガンドおよび／またはセロトニン作動性リガンドとしてのジヒドロイミダゾ［４，５−ｅ］インドールおよび７Ｈ−ピロロ［３，２−ｆ］キノキサリン誘導体 |
| HU0304046A HUP0304046A2 (hu) | 2001-04-30 | 2002-03-30 | Dihidro-imidazo[4,5-e]indol és 7H-pirrol[3,2-f]-kinoxalin-származékok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
| SK1447-2003A SK14472003A3 (sk) | 2001-04-30 | 2002-03-30 | Deriváty dihydroimidazo[4,5-e]indolu a 7H-pyrrolo[3,2- f]chinoxalínu ako ligandy nikotínacetylcholínového receptora a/lebo serotonergické ligandy, spôsob ich prípravy a ich použitie |
| ES02735200T ES2303857T3 (es) | 2001-04-30 | 2002-03-30 | Derivados de dihidroimidazo(4,5-e)indol y 7h-pirrol(3,2-f)quinoxalina como ligandos del receptor nicotinico de acetilcolina y/o ligandos serotonergicos. |
| PCT/EP2002/003582 WO2002088143A2 (en) | 2001-04-30 | 2002-03-30 | Dihydroimidazo[4,5-e]indole and 7h-pyrrolo[3,2-f]quinoxaline derivatives as nicotinic acetylcholine receptor ligands and/or serotonergic ligands |
| AT02735200T ATE394404T1 (de) | 2001-04-30 | 2002-03-30 | Dihydroimidazo 4,5-e indol- und 7h-pyrrolo 3,2-f chinoxalinderivate als nikotin-acetylcholin- rezeptorliganden und/oder serotonergische liganden |
| AU2002310904A AU2002310904B2 (en) | 2001-04-30 | 2002-03-30 | Dihydroimidazo[4,5-e]indole and 7H-pyrrolo[3,2-f]quinoxaline derivatives as nicotinic acetylcholine receptor ligands and/or serotonergic ligands |
| CA2445834A CA2445834C (en) | 2001-04-30 | 2002-03-30 | Dihydroimidazo[4,5-e]indole and 7h-pyrrolo[3,2-f]quinoxaline derivatives as nicotinic acetylcholine receptor ligands and/or serotonergic ligands |
| CZ20033195A CZ20033195A3 (cs) | 2001-04-30 | 2002-03-30 | Deriváty dihydroimidazo[4,5-e]indolu a 7H-pyrrolo[3,2-f]chinoxalinu jako ligandy nikotinacetylcholinového receptoru a/nebo serotonergické ligandy, způsob jejich přípravy a jejich použití |
| EP02735200A EP1383774B1 (en) | 2001-04-30 | 2002-03-30 | Dihydroimidazo¬4,5-e indole and 7h-pyrrolo¬3,2-f quinoxaline derivatives as nicotinic acetylcholine receptor ligands and/or serotonergic ligands |
| DE60226428T DE60226428D1 (de) | 2001-04-30 | 2002-03-30 | DIHYDROIMIDAZOi4,5-E INDOL- UND 7H-PYRROLOi3,2-F CHINOXALINDERIVATE ALS NIKOTIN-ACETYLCHOLIN-REZEPTORLIGANDEN UND/ODER SEROTONERGISCHE LIGANDEN |
| ARP020101529A AR033624A1 (es) | 2001-04-30 | 2002-04-26 | Derivados del dihidro-imidazo[4,5-e]indol y de la 7h-pirrolo[3,2-f]quinoxalina en calidad de ligandos nicotinicos del receptor para acetilcolina y/o de ligandos serotoninergicos, un procedimiento para su preparacion, las composiciones farmaceuticas que los contienen, y el empleo de los mismos para p |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10121215A DE10121215A1 (de) | 2001-04-30 | 2001-04-30 | Dihydro-imidazo[4,5-e]indol- und 7H-Pyrrolo[3,2-f]chinoxalin Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE10121215A1 true DE10121215A1 (de) | 2002-10-31 |
Family
ID=7683301
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10121215A Withdrawn DE10121215A1 (de) | 2001-04-30 | 2001-04-30 | Dihydro-imidazo[4,5-e]indol- und 7H-Pyrrolo[3,2-f]chinoxalin Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden |
| DE60226428T Expired - Lifetime DE60226428D1 (de) | 2001-04-30 | 2002-03-30 | DIHYDROIMIDAZOi4,5-E INDOL- UND 7H-PYRROLOi3,2-F CHINOXALINDERIVATE ALS NIKOTIN-ACETYLCHOLIN-REZEPTORLIGANDEN UND/ODER SEROTONERGISCHE LIGANDEN |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60226428T Expired - Lifetime DE60226428D1 (de) | 2001-04-30 | 2002-03-30 | DIHYDROIMIDAZOi4,5-E INDOL- UND 7H-PYRROLOi3,2-F CHINOXALINDERIVATE ALS NIKOTIN-ACETYLCHOLIN-REZEPTORLIGANDEN UND/ODER SEROTONERGISCHE LIGANDEN |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7279496B2 (https=) |
| EP (1) | EP1383774B1 (https=) |
| JP (1) | JP4593879B2 (https=) |
| AR (1) | AR033624A1 (https=) |
| AT (1) | ATE394404T1 (https=) |
| AU (1) | AU2002310904B2 (https=) |
| CA (1) | CA2445834C (https=) |
| CZ (1) | CZ20033195A3 (https=) |
| DE (2) | DE10121215A1 (https=) |
| ES (1) | ES2303857T3 (https=) |
| HU (1) | HUP0304046A2 (https=) |
| SK (1) | SK14472003A3 (https=) |
| WO (1) | WO2002088143A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1656093A (zh) * | 2002-05-30 | 2005-08-17 | 神经研究公司 | 3－取代的奎宁环及其用途 |
| US20050171079A1 (en) * | 2004-02-04 | 2005-08-04 | Schrimpf Michael R. | Amino-substituted tricyclic derivatives and methods of use |
| ZA200709038B (en) * | 2005-04-13 | 2009-01-28 | Neuraxon Inc | Substituted indole compounds having nos inhibitory activity |
| US7897766B2 (en) * | 2005-09-23 | 2011-03-01 | Abbott Laboratories | Amino-aza-adamantane derivatives and methods of use |
| CN101466709B (zh) * | 2006-04-13 | 2013-03-20 | 轴突公司 | 具有nos抑制活性的1,5和3,6-取代的吲哚化合物 |
| EA201000808A1 (ru) * | 2007-11-16 | 2011-04-29 | Ньюраксон, Инк. | Индольные соединения и способы лечения висцеральной боли |
| EP2219449A4 (en) * | 2007-11-16 | 2010-10-27 | Univ Arizona State | METHOD FOR THE TREATMENT OF EXPOSURE TO DAMAGING |
| WO2009062318A1 (en) * | 2007-11-16 | 2009-05-22 | Neuraxon, Inc. | 3,5-substituted indole compounds having nos and norepinephrine reuptake inhibitory activity |
| FR3165598A1 (fr) | 2024-08-14 | 2026-02-20 | Ultrawatt | Élément d’habillage d’une paroi et kit comportant au moins un tel élément |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4009565A1 (de) | 1990-03-24 | 1991-09-26 | Merck Patent Gmbh | Indolderivate |
| ATE157977T1 (de) * | 1992-10-13 | 1997-09-15 | Warner Lambert Co | Chinoxalinderivate als eaa antagonisten |
| US5843945A (en) | 1993-05-13 | 1998-12-01 | Neurosearch A/S | AMPA antagonists and a method of treatment |
| WO1994026747A1 (en) | 1993-05-13 | 1994-11-24 | Neurosearch A/S | Ampa antagonists and a method of treatment therewith |
| AU727608B2 (en) * | 1995-10-03 | 2000-12-14 | Scripps Research Institute, The | CBI analogs of CC-1065 and the duocarmycins |
| US6147096A (en) * | 1998-02-26 | 2000-11-14 | Ortho Mcneil Pharmaceutical, Inc. | Substituted pyrrolobenzimidazoles for treating inflammatory diseases |
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2001
- 2001-04-30 DE DE10121215A patent/DE10121215A1/de not_active Withdrawn
-
2002
- 2002-03-30 AU AU2002310904A patent/AU2002310904B2/en not_active Ceased
- 2002-03-30 AT AT02735200T patent/ATE394404T1/de not_active IP Right Cessation
- 2002-03-30 US US10/476,234 patent/US7279496B2/en not_active Expired - Fee Related
- 2002-03-30 EP EP02735200A patent/EP1383774B1/en not_active Expired - Lifetime
- 2002-03-30 JP JP2002585441A patent/JP4593879B2/ja not_active Expired - Fee Related
- 2002-03-30 DE DE60226428T patent/DE60226428D1/de not_active Expired - Lifetime
- 2002-03-30 CA CA2445834A patent/CA2445834C/en not_active Expired - Fee Related
- 2002-03-30 CZ CZ20033195A patent/CZ20033195A3/cs unknown
- 2002-03-30 ES ES02735200T patent/ES2303857T3/es not_active Expired - Lifetime
- 2002-03-30 SK SK1447-2003A patent/SK14472003A3/sk unknown
- 2002-03-30 WO PCT/EP2002/003582 patent/WO2002088143A2/en not_active Ceased
- 2002-03-30 HU HU0304046A patent/HUP0304046A2/hu unknown
- 2002-04-26 AR ARP020101529A patent/AR033624A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP4593879B2 (ja) | 2010-12-08 |
| HUP0304046A2 (hu) | 2004-04-28 |
| DE60226428D1 (de) | 2008-06-19 |
| JP2004529936A (ja) | 2004-09-30 |
| EP1383774B1 (en) | 2008-05-07 |
| CZ20033195A3 (cs) | 2004-02-18 |
| EP1383774A2 (en) | 2004-01-28 |
| ATE394404T1 (de) | 2008-05-15 |
| SK14472003A3 (sk) | 2004-04-06 |
| AU2002310904B2 (en) | 2008-01-10 |
| US20040142935A1 (en) | 2004-07-22 |
| WO2002088143A2 (en) | 2002-11-07 |
| AR033624A1 (es) | 2003-12-26 |
| WO2002088143A3 (en) | 2003-01-23 |
| CA2445834C (en) | 2011-06-28 |
| ES2303857T3 (es) | 2008-09-01 |
| US7279496B2 (en) | 2007-10-09 |
| CA2445834A1 (en) | 2002-11-07 |
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