DD299427A5 - Neue 1-oxa-2-oxo-8-aza-spiro(4,5)dekan-derivate und verfahren zu ihrer herstellung - Google Patents

Neue 1-oxa-2-oxo-8-aza-spiro(4,5)dekan-derivate und verfahren zu ihrer herstellung Download PDF

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Publication number
DD299427A5
DD299427A5 DD90343353A DD34335390A DD299427A5 DD 299427 A5 DD299427 A5 DD 299427A5 DD 90343353 A DD90343353 A DD 90343353A DD 34335390 A DD34335390 A DD 34335390A DD 299427 A5 DD299427 A5 DD 299427A5
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DD
German Democratic Republic
Prior art keywords
general formula
group
oxo
above meaning
oxa
Prior art date
Application number
DD90343353A
Other languages
German (de)
English (en)
Inventor
Edit Toth
Jozsef Toerley
Bela Hegedues
Laszlo Szporny
Bela Kiss
Eva Palosi
Dora Groo
Istvan Laszlovszky
Erzsebet Lapis
Adam Sarkadi
Andras Ambrus
Judit Laszy
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �������@������@����������@����@��Kk�� filed Critical �������@������@����������@����@��Kk��
Publication of DD299427A5 publication Critical patent/DD299427A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DD90343353A 1989-08-10 1990-08-09 Neue 1-oxa-2-oxo-8-aza-spiro(4,5)dekan-derivate und verfahren zu ihrer herstellung DD299427A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU894093A HU204529B (en) 1989-08-10 1989-08-10 Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
DD299427A5 true DD299427A5 (de) 1992-04-16

Family

ID=10966862

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90343353A DD299427A5 (de) 1989-08-10 1990-08-09 Neue 1-oxa-2-oxo-8-aza-spiro(4,5)dekan-derivate und verfahren zu ihrer herstellung

Country Status (13)

Country Link
EP (1) EP0414422B1 (da)
JP (1) JPH0377885A (da)
KR (1) KR950001022B1 (da)
AT (1) ATE103921T1 (da)
AU (1) AU623545B2 (da)
DD (1) DD299427A5 (da)
DE (1) DE69007905T2 (da)
DK (1) DK0414422T3 (da)
ES (1) ES2052181T3 (da)
HU (1) HU204529B (da)
IL (1) IL95321A (da)
NZ (1) NZ234845A (da)
ZA (1) ZA906301B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU204054B (en) * 1989-08-10 1991-11-28 Richter Gedeon Vegyeszet Process for producing new 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives and pharmaceutical compositions comprising same
KR940003491B1 (ko) * 1989-08-10 1994-04-23 리히터 게데온 베기에스제티 기아르 알.티 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
YU150489A (sh) * 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
HU204530B (en) * 1989-08-10 1992-01-28 Richter Gedeon Vegyeszet Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
FR2691459B1 (fr) * 1992-05-25 1995-06-09 Adir Nouveaux derives de la phenothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE60028754T2 (de) 1999-11-12 2007-05-31 Abbott Laboratories, Abbott Park Feste dispersion mit ritonavir, fenofibrat oder griseofulvin
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
JPWO2005032228A1 (ja) 2003-09-26 2007-11-15 株式会社ソニー・コンピュータエンタテインメント 携帯型電子装置
EP1716156A2 (en) * 2004-02-10 2006-11-02 F.Hoffmann-La Roche Ag Chemokine ccr5 receptor modulators
MX2009010503A (es) 2007-03-29 2009-10-19 Hoffmann La Roche Compuestos heterociclicos antiviricos.
EP3773597A4 (en) 2018-04-06 2022-06-08 Camp4 Therapeutics Corporation PHENOTHIAZINE DERIVATIVES AND THEIR USES

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1256404A (en) * 1968-06-07 1971-12-08 Dainippon Pharmaceutical Co 0-oxa-3,8-diazaspiro(4,5)decan-2,4-diones
DE2118339A1 (de) * 1971-04-15 1972-10-26 Yoshitomi Pharmaceutical Industries Ltd, Osaka (Japan) Pipendinspiroverbindungen
US4255432A (en) * 1979-09-06 1981-03-10 Syntex (U.S.A.) Inc. 8-[2-3-Indolyl)ethyl]-1-oxa-3-,8-diazaspiro[4.5]decan-2-ones, pharmaceutical compositions thereof and methods of use thereof
FR2615515B1 (fr) * 1987-05-22 1989-06-30 Adir Nouveaux derives du spiro 4, 5 decane, leur procede de preparation et les compositions pharmaceutiques les renfermant
YU150489A (sh) * 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost

Also Published As

Publication number Publication date
DE69007905D1 (de) 1994-05-11
HUT55784A (en) 1991-06-28
EP0414422A2 (en) 1991-02-27
AU623545B2 (en) 1992-05-14
KR910004633A (ko) 1991-03-29
DE69007905T2 (de) 1994-07-21
IL95321A0 (en) 1991-06-30
HU204529B (en) 1992-01-28
IL95321A (en) 1994-02-27
JPH0377885A (ja) 1991-04-03
DK0414422T3 (da) 1994-05-16
EP0414422A3 (en) 1991-07-24
ES2052181T3 (es) 1994-07-01
EP0414422B1 (en) 1994-04-06
ZA906301B (en) 1991-06-26
NZ234845A (en) 1992-03-26
KR950001022B1 (ko) 1995-02-07
ATE103921T1 (de) 1994-04-15
AU6080290A (en) 1991-02-14

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