DD297824A5 - N-substituierte aminoalkandiphosphonsaeuren - Google Patents

N-substituierte aminoalkandiphosphonsaeuren Download PDF

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Publication number
DD297824A5
DD297824A5 DD90338447A DD33844790A DD297824A5 DD 297824 A5 DD297824 A5 DD 297824A5 DD 90338447 A DD90338447 A DD 90338447A DD 33844790 A DD33844790 A DD 33844790A DD 297824 A5 DD297824 A5 DD 297824A5
Authority
DD
German Democratic Republic
Prior art keywords
hydroxy
salt
alk
amino
formula
Prior art date
Application number
DD90338447A
Other languages
German (de)
English (en)
Inventor
Knut A Jaeggi
Original Assignee
����`��@���k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ����`��@���k�� filed Critical ����`��@���k��
Publication of DD297824A5 publication Critical patent/DD297824A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839Polyphosphonic acids
    • C07F9/3873Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DD90338447A 1989-03-08 1990-03-06 N-substituierte aminoalkandiphosphonsaeuren DD297824A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH86689 1989-03-08

Publications (1)

Publication Number Publication Date
DD297824A5 true DD297824A5 (de) 1992-01-23

Family

ID=4197009

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90338447A DD297824A5 (de) 1989-03-08 1990-03-06 N-substituierte aminoalkandiphosphonsaeuren

Country Status (21)

Country Link
US (1) US5036058A (fi)
EP (1) EP0387194B1 (fi)
JP (1) JPH02279689A (fi)
KR (1) KR900014413A (fi)
AT (1) ATE117308T1 (fi)
AU (1) AU629298B2 (fi)
CA (1) CA2011586A1 (fi)
DD (1) DD297824A5 (fi)
DE (1) DE59008275D1 (fi)
DK (1) DK0387194T3 (fi)
ES (1) ES2067010T3 (fi)
FI (1) FI95264C (fi)
HU (1) HU206120B (fi)
IE (1) IE64984B1 (fi)
IL (1) IL93586A (fi)
MX (1) MX19785A (fi)
NO (1) NO174152C (fi)
NZ (1) NZ232805A (fi)
PH (1) PH26923A (fi)
PT (1) PT93353B (fi)
ZA (1) ZA901742B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4015715A1 (de) * 1990-05-16 1991-11-21 Bayer Ag Neuartige oligophosphate mit antiviraler wirkung
IE912115A1 (en) * 1990-06-25 1992-01-01 Takeda Chemical Industries Ltd Bisphosphonic acid derivatives, their production and use
US5159108A (en) * 1990-09-18 1992-10-27 Merck & Co., Inc. Process for preparing an antihypercalcemic agent
DE69116838T2 (de) * 1990-12-19 1996-06-13 Takeda Chemical Industries Ltd Bisphosphonsäurederivate, ihre Produktion und ihre Verwendung
IT1244698B (it) * 1991-02-01 1994-08-08 Gentili Ist Spa Acidi aril-o arilalchil-acil ammino-alchil-idrossidifosfonici, procedimento per la loro preparazione e loro uso in terapia osteo-articolare e dei tessuti connettori in generale
TW207543B (fi) * 1991-08-27 1993-06-11 Ciba Geigy Ag
EP0541037A3 (en) * 1991-11-06 1997-02-26 Takeda Chemical Industries Ltd Squalene synthetase inhibitory composition and use thereof
US5283057A (en) * 1992-04-24 1994-02-01 The Procter & Gamble Company Risedronate in oral compositions
JP2006176499A (ja) * 2004-11-25 2006-07-06 Nippon Seibutsu Seizai:Kk 眼疾患治療剤
FR2926081B1 (fr) * 2008-01-03 2010-02-19 Univ Nantes Derives d'acide hydroxy-bisphosphonique comme vecteur ciblant le tissu osseux
FR2973378B1 (fr) 2011-03-28 2013-10-04 Atlanthera Derives d'acide hydroxybisphosphonique bifonctionnels

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3203308A1 (de) * 1982-01-27 1983-07-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Diphosphonsaeure-derivate und diese enthaltende pharmazeutische praeparate
FR2531088B1 (fr) * 1982-07-29 1987-08-28 Sanofi Sa Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation
GB8419489D0 (en) * 1984-07-31 1984-09-05 Leo Pharm Prod Ltd Chemical compounds
US4639338A (en) * 1984-08-06 1987-01-27 Ciba-Geigy Corporation Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
IT1187828B (it) * 1985-05-24 1987-12-23 Gentili Ist Spa Composizione farmaceutica a base di difosfonati per il trattamento dell aretrosi
ES2039237T3 (es) * 1986-04-24 1993-09-16 Fujisawa Pharmaceutical Co., Ltd. Procedimiento para preparar nuevos compuestos de acido difosfonico.
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
GB8618259D0 (en) * 1986-07-25 1986-09-03 Leo Pharm Prod Ltd Pharmaceutical compositions
EP0272208B1 (de) * 1986-11-21 1991-06-12 Ciba-Geigy Ag Aromatisch substituierte Azacyclo-alkylalkandiphosphonsäuren
US4933472A (en) * 1988-04-08 1990-06-12 Yamanouchi Pharmaceutical Co., Ltd. Substituted aminomethylenebis(phosphonic acid) derivatives

Also Published As

Publication number Publication date
KR900014413A (ko) 1990-10-23
EP0387194A1 (de) 1990-09-12
IE64984B1 (en) 1995-09-20
NO174152C (no) 1994-03-23
NZ232805A (en) 1992-06-25
US5036058A (en) 1991-07-30
HU901348D0 (en) 1990-05-28
FI95264C (fi) 1996-01-10
HU206120B (en) 1992-08-28
FI95264B (fi) 1995-09-29
AU4988490A (en) 1990-09-13
CA2011586A1 (en) 1990-09-08
PT93353A (pt) 1990-11-07
ES2067010T3 (es) 1995-03-16
ATE117308T1 (de) 1995-02-15
HUT53112A (en) 1990-09-28
AU629298B2 (en) 1992-10-01
FI901103A0 (fi) 1990-03-05
PH26923A (en) 1992-12-03
JPH02279689A (ja) 1990-11-15
DK0387194T3 (da) 1995-03-20
PT93353B (pt) 1996-02-29
NO174152B (no) 1993-12-13
IL93586A (en) 1995-06-29
IL93586A0 (en) 1990-12-23
NO901077L (no) 1990-09-10
ZA901742B (en) 1990-10-31
DE59008275D1 (de) 1995-03-02
NO901077D0 (no) 1990-03-07
MX19785A (es) 1994-03-31
IE900809L (en) 1990-09-08
EP0387194B1 (de) 1995-01-18

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