DD253620A5 - Verfahren zur herstellung von pyrrolo-benzimidazolen - Google Patents
Verfahren zur herstellung von pyrrolo-benzimidazolen Download PDFInfo
- Publication number
- DD253620A5 DD253620A5 DD86286253A DD28625386A DD253620A5 DD 253620 A5 DD253620 A5 DD 253620A5 DD 86286253 A DD86286253 A DD 86286253A DD 28625386 A DD28625386 A DD 28625386A DD 253620 A5 DD253620 A5 DD 253620A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- methyl
- group
- pyrrolo
- dihydro
- het
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853501497 DE3501497A1 (de) | 1985-01-18 | 1985-01-18 | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD253620A5 true DD253620A5 (de) | 1988-01-27 |
Family
ID=6260116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD86286253A DD253620A5 (de) | 1985-01-18 | 1986-01-16 | Verfahren zur herstellung von pyrrolo-benzimidazolen |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4695567A (ru) |
| EP (1) | EP0189103B1 (ru) |
| JP (1) | JPS61167689A (ru) |
| AT (1) | ATE59649T1 (ru) |
| AU (1) | AU580832B2 (ru) |
| DD (1) | DD253620A5 (ru) |
| DE (2) | DE3501497A1 (ru) |
| DK (1) | DK20786A (ru) |
| ES (2) | ES8801832A1 (ru) |
| FI (1) | FI81579C (ru) |
| GR (1) | GR860144B (ru) |
| HU (1) | HU194242B (ru) |
| IL (1) | IL77582A (ru) |
| SU (1) | SU1470191A3 (ru) |
| ZA (1) | ZA86360B (ru) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3445669A1 (de) * | 1984-12-14 | 1986-06-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3531678A1 (de) * | 1985-09-05 | 1987-03-12 | Boehringer Mannheim Gmbh | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3626664A1 (de) * | 1986-08-07 | 1988-02-11 | Boehringer Mannheim Gmbh | Tricyclische benzotriazole, verfahren zu ihrer herstellung sowie arzneimittel |
| DE3639466A1 (de) * | 1986-11-18 | 1988-05-19 | Thomae Gmbh Dr K | Neue pyrrolo-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE3642315A1 (de) * | 1986-12-11 | 1988-06-23 | Boehringer Mannheim Gmbh | Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel |
| DE3701277A1 (de) * | 1987-01-17 | 1988-07-28 | Boehringer Mannheim Gmbh | Neue tricyclische benzimidazole, verfahren zu ihrer herstellung und verwendung als arzneimittel |
| DE3706427A1 (de) * | 1987-02-27 | 1988-09-08 | Boehringer Mannheim Gmbh | Neue substituierte 3h-indole, zwischenprodukte, verfahren zu ihrer herstellung sowie arzneimittel |
| DE3740985A1 (de) * | 1987-12-03 | 1989-06-15 | Boehringer Mannheim Gmbh | Verwendung linear anellierter tricyclen als hemmer der erythrozytenaggregation |
| US4963677A (en) * | 1987-12-30 | 1990-10-16 | Orion Corporation Ltd. | Heterocyclic lactam compounds |
| EP0322746B1 (en) * | 1987-12-30 | 1996-05-29 | Orion Corporation Limited | Heterocyclic compounds |
| DE3803775A1 (de) * | 1988-02-09 | 1989-08-17 | Boehringer Mannheim Gmbh | Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
| DE3809868A1 (de) * | 1988-03-24 | 1989-10-05 | Boehringer Mannheim Gmbh | Neue heterocyclisch substituierte 5,7-dihydro-pyrrolo(3,2-f)benzoxazol-6-one, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
| DE4027592A1 (de) * | 1990-08-31 | 1992-03-05 | Beiersdorf Ag | Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen |
| TW200626149A (en) * | 2004-09-24 | 2006-08-01 | Hoffmann La Roche | Tricycles, their manufacture and use as pharmaceutical agents |
| US7285569B2 (en) | 2004-09-24 | 2007-10-23 | Hoff Hoffmann-La Roche Inc. | Tricycles, their manufacture and use as pharmaceutical agents |
| US20060142247A1 (en) * | 2004-12-17 | 2006-06-29 | Guy Georges | Tricyclic heterocycles |
| BRPI0608178A2 (pt) * | 2005-04-14 | 2009-11-17 | Hoffmann La Roche | derivados de aminopirazol, sua fabricação, composição farmacêutica e uso como agentes farmacêuticos |
| US20060235013A1 (en) * | 2005-04-14 | 2006-10-19 | Guy Georges | Tricyclic azole derivatives |
| EP1966213A1 (en) * | 2005-12-15 | 2008-09-10 | F.Hoffmann-La Roche Ag | Tricyclic lactam derivatives, their manufacture and use as pharmaceutical agents |
| WO2007107346A1 (en) * | 2006-03-23 | 2007-09-27 | F. Hoffmann-La Roche Ag | Substituted indazole derivatives, their manufacture and use as pharmaceutical agents |
| MX2015003330A (es) | 2012-09-13 | 2015-06-05 | Hoffmann La Roche | 2-oxo-2,3-dihidro-indoles para el tratamiento de trastornos del sistema nervioso central (cns). |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN148930B (ru) * | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
| EP0033612B1 (en) * | 1980-02-02 | 1984-04-11 | Beecham Group Plc | Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them |
| US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
| US4548946A (en) * | 1981-03-26 | 1985-10-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory and/or analgesic 1,8-Dihydro-(or 3,8-dihydro)-8-aryl-2-[(substituted)thio]-indeno[1,2-d]imidazoles and their corresponding sulfoxides and sulfones |
| DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| GB8307865D0 (en) * | 1983-03-22 | 1983-04-27 | Fujisawa Pharmaceutical Co | Benzimidazole derivatives |
| DE3410168A1 (de) * | 1984-03-20 | 1985-09-26 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue isochinolin-dione, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| PL144822B1 (en) * | 1984-05-12 | 1988-07-30 | Boehringer Mannheim Gmbh | Method of obtaining novel pyrolobenzimidazoles |
| US4552876A (en) * | 1984-07-09 | 1985-11-12 | Usv Pharmaceutical Corp. | Bisbenzoxazines and pharmaceutical use |
| DE3445669A1 (de) * | 1984-12-14 | 1986-06-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1985
- 1985-01-18 DE DE19853501497 patent/DE3501497A1/de not_active Withdrawn
-
1986
- 1986-01-13 IL IL77582A patent/IL77582A/xx unknown
- 1986-01-14 AU AU52245/86A patent/AU580832B2/en not_active Ceased
- 1986-01-15 AT AT86100451T patent/ATE59649T1/de not_active IP Right Cessation
- 1986-01-15 DE DE8686100451T patent/DE3676313D1/de not_active Expired - Lifetime
- 1986-01-15 EP EP86100451A patent/EP0189103B1/de not_active Expired - Lifetime
- 1986-01-16 DK DK20786A patent/DK20786A/da not_active Application Discontinuation
- 1986-01-16 DD DD86286253A patent/DD253620A5/de unknown
- 1986-01-17 JP JP61006617A patent/JPS61167689A/ja active Pending
- 1986-01-17 US US06/820,259 patent/US4695567A/en not_active Expired - Fee Related
- 1986-01-17 ZA ZA86360A patent/ZA86360B/xx unknown
- 1986-01-17 SU SU864012604A patent/SU1470191A3/ru active
- 1986-01-17 FI FI860228A patent/FI81579C/fi not_active Application Discontinuation
- 1986-01-17 ES ES551002A patent/ES8801832A1/es not_active Expired
- 1986-01-17 HU HU86241A patent/HU194242B/hu not_active IP Right Cessation
- 1986-01-20 GR GR860144A patent/GR860144B/el unknown
-
1987
- 1987-12-09 ES ES557777A patent/ES8900123A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| HUT41791A (en) | 1987-05-28 |
| GR860144B (en) | 1986-05-16 |
| FI81579C (fi) | 1990-11-12 |
| ES8801832A1 (es) | 1988-03-01 |
| HU194242B (en) | 1988-01-28 |
| EP0189103B1 (de) | 1991-01-02 |
| ES8900123A1 (es) | 1989-01-16 |
| EP0189103A2 (de) | 1986-07-30 |
| IL77582A (en) | 1990-01-18 |
| ES551002A0 (es) | 1988-03-01 |
| AU580832B2 (en) | 1989-02-02 |
| DE3676313D1 (de) | 1991-02-07 |
| DK20786A (da) | 1986-07-19 |
| DE3501497A1 (de) | 1986-07-24 |
| FI860228A (fi) | 1986-07-19 |
| ES557777A0 (es) | 1989-01-16 |
| FI860228A0 (fi) | 1986-01-17 |
| DK20786D0 (da) | 1986-01-16 |
| EP0189103A3 (en) | 1987-12-23 |
| JPS61167689A (ja) | 1986-07-29 |
| ATE59649T1 (de) | 1991-01-15 |
| SU1470191A3 (ru) | 1989-03-30 |
| FI81579B (fi) | 1990-07-31 |
| AU5224586A (en) | 1986-07-24 |
| ZA86360B (en) | 1986-09-24 |
| US4695567A (en) | 1987-09-22 |
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