DD220225A5 - Verfahren zur herstellung einer festkoerperdispersion von chlorthalidon - Google Patents

Verfahren zur herstellung einer festkoerperdispersion von chlorthalidon Download PDF

Info

Publication number
DD220225A5
DD220225A5 DD84260896A DD26089684A DD220225A5 DD 220225 A5 DD220225 A5 DD 220225A5 DD 84260896 A DD84260896 A DD 84260896A DD 26089684 A DD26089684 A DD 26089684A DD 220225 A5 DD220225 A5 DD 220225A5
Authority
DD
German Democratic Republic
Prior art keywords
chlorothalidone
solution
alkanol
methanol
chlorthalidone
Prior art date
Application number
DD84260896A
Other languages
German (de)
English (en)
Inventor
Nevedita Pandit
Stephen T Horhota
Original Assignee
Boehringer Ingelheim Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Ltd filed Critical Boehringer Ingelheim Ltd
Publication of DD220225A5 publication Critical patent/DD220225A5/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Dental Preparations (AREA)
  • Indole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DD84260896A 1983-03-16 1984-03-14 Verfahren zur herstellung einer festkoerperdispersion von chlorthalidon DD220225A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47589883A 1983-03-16 1983-03-16

Publications (1)

Publication Number Publication Date
DD220225A5 true DD220225A5 (de) 1985-03-27

Family

ID=23889624

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84260896A DD220225A5 (de) 1983-03-16 1984-03-14 Verfahren zur herstellung einer festkoerperdispersion von chlorthalidon

Country Status (20)

Country Link
EP (1) EP0125420B1 (no)
JP (1) JPS59176212A (no)
KR (1) KR880001755B1 (no)
AT (1) ATE31024T1 (no)
AU (1) AU562929B2 (no)
CA (1) CA1212329A (no)
DD (1) DD220225A5 (no)
DE (1) DE3467707D1 (no)
DK (1) DK162878C (no)
ES (1) ES8602633A1 (no)
FI (1) FI82188C (no)
GR (1) GR81478B (no)
HU (1) HU191596B (no)
IE (1) IE57031B1 (no)
IL (1) IL71248A (no)
NO (1) NO164956C (no)
NZ (1) NZ207514A (no)
PT (1) PT78259B (no)
YU (1) YU43349B (no)
ZA (1) ZA841916B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4933360A (en) * 1983-03-16 1990-06-12 Boehringer Ingelheim Pharmaceuticals, Inc. Novel chlorthalidone process and product
DE3612212A1 (de) * 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen
WO1988000040A1 (en) * 1986-07-02 1988-01-14 American Health Products Corporation Topical hair growing composition and kit
US5955475A (en) * 1997-06-30 1999-09-21 Endo Pharmaceuticals Inc. Process for manufacturing paroxetine solid dispersions
US6264981B1 (en) * 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3055904A (en) * 1957-11-04 1962-09-25 Geigy Chem Corp New isoindoline derivatives
US4128632A (en) * 1978-02-13 1978-12-05 Merck & Co., Inc. Solubilization of Rafoxanide
US4285665A (en) * 1978-05-08 1981-08-25 Johnson, Matthey & Co., Limited Engines

Also Published As

Publication number Publication date
HUT34343A (en) 1985-03-28
DE3467707D1 (en) 1988-01-07
ZA841916B (en) 1985-11-27
FI82188C (fi) 1991-02-11
EP0125420B1 (en) 1987-11-25
IE840647L (en) 1984-09-16
FI841019A (fi) 1984-09-17
FI841019A0 (fi) 1984-03-14
DK162878C (da) 1992-05-18
EP0125420A2 (en) 1984-11-21
KR880001755B1 (ko) 1988-09-12
AU562929B2 (en) 1987-06-25
PT78259B (en) 1986-08-08
FI82188B (fi) 1990-10-31
ES530628A0 (es) 1985-12-01
DK162878B (da) 1991-12-23
DK156784A (da) 1984-09-17
AU2569684A (en) 1984-09-20
JPS59176212A (ja) 1984-10-05
KR840007874A (ko) 1984-12-11
YU43349B (en) 1989-06-30
IL71248A (en) 1987-02-27
IL71248A0 (en) 1984-06-29
IE57031B1 (en) 1992-03-25
DK156784D0 (da) 1984-03-15
NO164956C (no) 1990-12-05
ATE31024T1 (de) 1987-12-15
PT78259A (en) 1984-04-01
NZ207514A (en) 1987-02-20
EP0125420A3 (en) 1985-03-13
ES8602633A1 (es) 1985-12-01
HU191596B (en) 1987-03-30
YU45884A (en) 1987-06-30
NO164956B (no) 1990-08-27
GR81478B (no) 1984-12-11
NO841010L (no) 1984-09-17
CA1212329A (en) 1986-10-07

Similar Documents

Publication Publication Date Title
EP0078430B2 (de) Verfahren zur Herstellung von festen, schnellfreisetzenden Arzneizubereitungen mit Dihydropyridinen
DE60026144T2 (de) Benzamidformulierung mit histon-deacetylase-inhibitoraktivität
EP0317878B1 (de) Stabilisierte Arzneistoffe, Verfahren zu ihrer Herstellung sowie stabile Arzneizubereitungen
EP0387782B2 (de) Feste pharmazeutische Präparate und Verfahren zu ihrer Herstellung
EP0128483B1 (de) Neue galenische Zubereitungsformen von oralen Antidiabetika und Verfahren zu ihrer Herstellung
EP0272336B1 (de) Gegenüber Lichteinfluss stabilisiertes Nifedipin-Konzentrat und Verfahren zu seiner Herstellung
DE3505433A1 (de) Direkttablettierhilfsmittel
CH659467A5 (de) Verfahren zur herstellung von nifedipin-trockenpraeparaten.
EP0793958B1 (de) Verfahren zur Herstellung Von Fenofibrat-Präparaten
EP1094841B1 (de) Pharmazeutische levothyroxinzubereitung
DE69730241T2 (de) Feste lösung eines fungizids mit erhöhter bioverfügbarkeit
EP0275468B1 (de) Clodronat-haltige Arzneimittel und Verfahren zur Herstellung derselben
EP0184754B1 (de) Pankreasenzympräparate und Verfahren zu deren Herstellung
DE69001003T2 (de) Vitamin-b12-zusammensetzung.
DD220225A5 (de) Verfahren zur herstellung einer festkoerperdispersion von chlorthalidon
DE19740983A1 (de) Verfahren zur Erschwerung der Extraktion von Wirkstoffen aus Tabletten
DE3419128A1 (de) Dihydropyridinpraeparate und verfahren zu ihrer herstellung
DE69824971T2 (de) Stabilisierte Zusammensetzung aus Tetrahydropyrrolo [1,2-a] Pyrazin-4-Spiro-3'-Pyrrolidin
DE69325996T2 (de) Aminoguanidin-spruehtrocknungsverfahren
AT412213B (de) Verfahren zur trocknung von amoxicillin oder amoxicillin-hältigen, oralen, festen pharmazeutischen zusammensetzungen unter verwendung eines gases mit einer definierten gasfeuchte
DE69920039T2 (de) Quinapril magnesium enthaltende, pharmazeutisch wirksame zusammensetzung
EP0164587A2 (de) Nifedipinpräparate und Verfahren zu ihrer Herstellung
US4933360A (en) Novel chlorthalidone process and product
EP1631252B1 (de) Verfahren zur herstellung einer festen pharmazeutischen zusammensetzung
DE60102938T2 (de) Lagerstabile Granulate, die S-Adenosylmethionin enthalten, und Verfahren zu ihrer Herstellung

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee