DD219034A3 - BLEACHING AND BACTERICIDES, VIRUZIDES AND FUNGICIDES - Google Patents

Abstract

1. Bactericidal, virucidal and fungicidal bleaching product for washing, bleaching, disinfection and purification processes in the temperature range of 20 to 90 C, preferably 30 to 60 C, characterised in that it contains, perhaps in addition to already known washing, bleaching, disinfection and/or purification components, a combination of 10 to 90 parts by weight of one or more peroxygen compounds and 90 to 10 parts by weight of 1,5-diacylhexahydro-1,3,5-triazine-2,4-dione.

Description

VEB Leuna-Werke Leuna

"Walter. Ulbricht !! '>

LP 8198

Title of the invention. ,

Bleaching and bactericidal, virucidal and fungicidal agent Field of the invention.

The invention relates to a bleaching and antimicrobial agent for washing, bleaching ^ disinfecting and cleaning processes, which are carried out in particular at low temperatures.

Characteristic of the known technical solutions

Inorganic peroxygen compounds, in particular sodium perborate "and ijatriumcarbonatperoxohydrat are part of commercially available detergents and cleaning agents, it is known that these oxygen bleaches only have a very low Bleichvermoegen at temperatures below 80 ⁰ C. An antimicrobial effect is herkoemmllchen detergents and cleaning agents also only Temperatures above 8Q ⁰ C to achieve · The sole use of such means for bleaching and disinfecting · temperature-sensitive textiles therefore results in only insufficient effects.

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In order to achieve a sufficient antimicrobial effect in the washing process at medium temperatures (4P ⁰ C - 6O ⁰ G) z euf special disinfectants. Eg formaldehyde,. Phenols, quaternary ammonium salts, ¹ heterocycles (DD-PS 135 287) added. Such equipped washing and cleaning agents have no bleaching effect and are subject to considerable disadvantages due to the necessary relatively high use concentration of the disinfectant and the restricted operating conditions. .

The special requirements for health protection do not allow use in household detergents, especially from a dermatological point of view. Although the proposed according to DD-PS 149 678 Use of the antimicrobial agent 'hexahydro-1,3,5-triazine-2,4-dione (DHT) -shows a good antimicrobial effect at application temperatures around 60 * ⁰ G and eliminates this disadvantage, However, the observed release of oxygen in peroxide-containing detergents does not lead to an improvement in the bleaching effect in the temperature range up to 60 ⁰ C. The effect corresponds to that of a typical catalase for peroxides.

A better bleaching effect even at low wash temperatures can be known verb connections, in particular organic Persaeureh, when using organic peroxygen, be achieved ^ These Persaeuren also have an excellent antimicrobial effect even at low temperatures and low concentrations of use. However, the incorporation of such compounds into powdered detergents and cleaners and their handwashing as well as the guarantee of storage stability are problematic. i

It is also known that inorganic peroxygen compounds von'Aktivatoren by adding, in particular of organic reaktionsfaehigen ST-acyl and 0-acyl compounds at temperatures below 8O ⁰ C to be bleach-effective and exhibit good antimicrobial activity. Suitable activators are, for example, tetraacetylglycoluril, tetraacetylethylenediamine,

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Triacetylcyanurat, Pentaacetyiglukose, acetylsalicylic acid and diacetyldiketopiperazine, wherein tetraacetylaethylenediamine is already used in detergents. Such compounds react in aqueous solution with the inorganic peroxygen compound to form organic persalts, e.g. , Peracetic acid, which already at low temperatures allows good bleaching ability and antimicrobial action. In choosing suitable activators, there is a high degree of perhydrolysis leading to the desired formation of the organic peracid and a low tendency to hydrolysis in an alkaline medium leading to premature loss of activator action by formation of inactive salts of the organic acids , he wishes. A premature reaction of the activator with the inorganic peroxygen carrier during storage of ready-to-use detergents and cleaners must be avoided. V,.

The activators known hitherto are not a solution to this problem. A comprehensive practical application is counteracted by the relatively high use concentration required for activators with adequate storage stability, but in some cases insufficient activator action and the high raw material costs. A general structure-activity relationship is unknown. ι ^; , '

Sin another disadvantage of the known activators is the fact that in addition to the formation of organic peracids compounds are formed, which have no positive effect on the further washing and disinfection process.

Object of the invention

The aim of the invention is to provide a bleaching and bactericidal, virucidal and fungicidal agent for washing, bleaching, Desinfekirions- and cleaning processes, which has a high bleaching effect and a broad antimicrobial spectrum especially at low washing temperatures. The use of the agent according to the invention must not lead to a higher substrate damage than with the use of conventional oxygen bleach, even at relatively high temperatures. The storage stability of the bleaching

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the bactericidal, virucidal and fungicidal agent in washing · bleach-disinfectant cleaning agents must be guaranteed, the use concentration must be as low as possible, and a smooth incorporation with known technologies must be possible.

The aim of the invention is also the realization of an antimicrobial en. Langzeitwirküng. ...

Explanation of the essence of the invention _r

The object of the invention is a combination of a peroxygen compound with an activator, which itself has antimicrobial properties, as part of a, in the temperature range of 20 to 90 ⁰ G, preferably 30 to 60 ⁰ G, effective ·. <Bleaching and bactericidal, virucidal, and fungicidal agents,

This task is solved by a combination of 10 to 90 parts by mass of one or more. Peroxygen compounds and 90 to 10 parts by weight of 1, 5-diacyls: ahydro-1, 3,5-triazine-2,4-dione (DAHT), optionally in addition to already known washing, bleaching, disinfecting and / or detergent components.

Preferably, a combination of 30 to 70 parts by weight of peroxygen compounds and 10 to 30 parts by weight of 1,5-diacylhexahydro-1,3,5-triazine-2,4-dione. used. An advantageous combination consists of sodium perborate, sodium carbonate peroxohydrate or urea perhydrate and 1, 5-diacetylhe3;

DAHT can be prepared from formaldehyde and urea with subsequent acylation, e.g. after A. Piskala, I. Gut ', ·, Coll. Czech. Chem, Gommum. 27 1562 (1962) or after G. Östrogovich, R. Vidac; Rev. Ghim. (Bucharest) 20 (10) 606 (1969). The bleaching and bactericidal, virucidal and fungicidal agent advantageously contains, in addition to 5 to 95% by mass, preferably 10 to 50% by mass, of disinfecting components which are still known in the combination of the invention. , · It is also beneficial to combine detergents of known composition in amounts of from 1 to 30% by weight,

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preferably 5 to 15% by weight, to be added. Surprisingly, perhydrolysis and hydrolysis of the bleach activator 1,5-diacetylhexahydro-1,3,5-triazine-2,4-dione are complete, and oxidative degradation of the remaining base hexahydro-1,3,5-triazine-2,4 Dione does not take place under the conditions of the washing process, so that the disinfecting effect of this compound according to DD-PS 149 678 can be used. Thus, the specific antimicrobial effect of the organic peracid, which is only relatively short-lived by relatively rapid decomposition, in alkaline solution, supplemented by the action of hexahydro-1,3,5-triazine-2,4-dione, 1 , 5-Diacetylhexahydro-i, 3,5-triazine-2,4-dione has a compared to known activators ^ significantly, higher activation effect for inorganic peroxygen compounds in addition to a practical requirements corresponding storage stability in wash-bleach disinfection and detergents. '. ,

A comparable activation effect has diacetyldiketopiperazine. However, this prior art activator is extremely sensitive to hydrolysis "and unsuitable for practical use in detergents and cleaners.

The inventive agent is not irritating to skin and mucous membranes, non-toxic and non-corrosive. The application can be done both in the industrial sector and in the household. Application-technical investigations show that when using the composition according to the invention compared to conventional peroxygen bleaching agents and known detergent-containing detergents, no increased damage to the fibers on the treated textiles can be observed. In the following, the invention will be explained with reference to some examples, without thereby limiting them.

applications

Example 1 .

A bleaching and antimicrobial agent exists

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from · ι

50% by weight of sodium perborate and. '.

'50% by weight of 1, 5-diacetylhe3: ahydro-1, 3,5-triazine-2, .4-dione

For bleaching at low temperatures and an antimicrobially effective Wa schmitt els production "14 parts of the erf indungsgemaessen agent with 86 _s parts of a" detergent are mixed conventional Zusammensetzung.ohne Perboratzusatz - (formulation A) Comparatively are formulations having the same composition of quantitative below. Use of the known bleach activators.

Pentaacetylglucose formulation B

Acetylsalicylic acid formulation C ·.

Tetraacetylethylenediamine formulation .D <, ... ·

Tetraacetylglycoluril, formulation B

Diacetyldiketopiperazine Formulation F

used. <; , .

The efficacy of the composition of the invention was determined under practical conditions using formulations A through P. To carry out the experiments, a laboratory washing machine of the type HScourotester !! used (washing time 35 min, concentration 5 g / l, liquor ratio 1:80, temperature 60 ⁰ C). '

The test fabric used was a cotton fabric dyed with sulfur green B, which corresponds in its sensitivity to the tissues impregnated with Immedialgruen BTM with respect to its oxidant properties. ,

The difference between the measured remission rates (R) before sewing and after the second wash was used for evaluation.

Table 1 '

Recipe <. ' , A; 3 CDEFR 18.5; 13.9 13.9 15.9 16.2 18.7

To. Assessment of storage stability was 280 g each of formulations A to F in GEK cartons at 20 - 25 ⁰ Q and 50 - 70%

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Rel. · Humidity .- · stored for 8 weeks and the active oxygen loss (%) determined. (Table 2). '

Table 2

Recipe A B 'C D. E F'. <

Active oxygen. ·. : loss (%) 26 .18 40 24 25 80

Example 2

To test the antimicrobial effectiveness was a bleaching and antimicrobial agent,.: Consisting of

11,8 '·% 1, 5-di, acetylhe: xahydro-1,5,3-triazine-2,4-dione and ^; · 88.2 % sodium perborate.

 used. 17 parts of this agent were mixed with 83 parts of a conventional detergent without perborate additive (formulation G). For testing under practical conditions, sterile cloth pieces of linen were 15 minutes in a standard suspension contaminated with test microbes. After drying, they are inserted into the solution of the detergent formulation G at the selected temperature, taken after 60 min and twice with distilled water ge .spuelt. The pieces of fabric were introduced into suitable hauling media containing evidence of the elimination of microbicidal after-effects to demonstrate efficacy.

The evaluation was carried out after 6 days (at 37 ⁰ C bebruetet). The evaluation took place after the following Bonitursehema:

0.- complete detachment of the test germs.

1 - sufficient effectiveness

2 - mean effectiveness

3 - weak effectiveness

4 - no effectiveness

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Following test germs were used;

(1) Staphylococcus aureus SG 51.1

(2) Escherichia coIi-FMH 3 .. ''.

(3) Pseudomonas eruginosa RLD 1

The comparison was carried out with a formulation of the same formulation using the active ingredient hexahydro-1,3,5-triazine-2,4-dione (formulation H).

Table 3

Temperature 40 ^° C. 50 ^° C. 60 ^° C.

Test germ 12 3 1 2 3 123

Recipe GOOO 000 000

'Recipe H 3 0 3 2 0 0 0 0 0

'Example 3 /. , , ·,;. ^·:; ,

To prepare a bleaching at low temperatures and antimicrobial 'effective O ₁ , 5% detergent solution (Formulation I), were to ^%> 84 parts of a bleach' pure, detergent usual composition 8 parts of hydrogen peroxide (30%) and 8 Parts of the bleach activator 1,5-diacetylhexahydro-i, 3,5-triazine-2,4-dione dissolved in the detergent liquor to be prepared.

The effectiveness of the lead-acid activator according to the invention was determined under practical conditions using formulations A to I. The experimental conditions and the evaluation were selected analogously to Example 1.

Table 4 1 A 1 B 1 C 9 1 D 8th 1 e 2 1 8th, Ί- 1 I recipe 8.5 3.9 3, 5, 8.1 R /

Example 4. , ,

Sin bleaching and antimicrobial agent, consisting of

38.5 wt .-% urea perhydrate ^ ¹ wt 61.5 -.% Of 1,5-Diacetylhexahydro-i, 3,5-triazine-2,4-dione,

was used as the agent of the invention. , ι

For the preparation of a low-temperature bleaching and antimicrobially active detergent, 23 parts of the inventive composition were mixed with 77 parts of detergent of conventional composition (without perborate content) (formulation K). By comparison, formulations using known bleach activators were used. The effectiveness of the agent according to the invention was determined under practical conditions using Formulas A to I. , The experimental conditions as well as the evaluation correspond to example 1 .. ". ^: .

Table 5 ·. ,

Recipe A B '. 0 D E P I K R 18.5 13.9 13.9 15.9 '' .16.2. 18.7 18.1 18.4

Claims (5)

- 10 words of invention '. * 1. bleaching and bactericidal, virucides and fungicides Agent for washing, bleaching, disinfecting and cleaning processes in the temperature range from 20 to 90 ^° C, preferably 30 to 60 ⁰ C, characterized in that it, ¹ optionally in addition to already 'known' washing, bleaching, Dfsinf ektions- and / or detergent components, a combination of 10 to 90 parts by weight of one or more oxygen compounds and 90 to 10 parts by weight of 1,5-diacylhe: ahydro- • 1,3,5-triazine ~ 2,4-dione. '' .. Bleaching and bactericidal, virucidal and fungicidal composition according to item 1, characterized in that the combination contained comprises 30 to 70 parts by weight of one or more peroxygen compounds and 70 to 30 parts by weight of 1,5-diacylhexahydro-1,3,3-triazine 2,4-dion exists » 3. Bleaching and bactericidal, virucidal and fungicidal,  , Compositions according to items 1 and 2, characterized in that the combination contained consists of peroxydium perborate, sodium carbonate peroxohydrate or urea perhydrate and 1,5-diacetylhexahydro-1,3,5-triazine-2,4-dione. * sr 4. Bleicherides and bactericidal, virucidal and fungicidal agent according to items 1 to 3, characterized in that it contains in addition to 5 to 95'Masse-, preferably 10 to 50% by mass, the inventive combination of known components of disinfectants. Bleaching and bactericidal, virucidal and fungicidal agents according to items 1 to 3, characterized in that it contains, in addition to 1 to 30% by mass, preferably 5 to 15% by mass, of the combination washing and cleaning composition according to the invention. ._. Contains medium of known composition.