DD133521A5 - Verfahren zur freisetzung von antibiotica aus antibioticahaltigen kunststoffpartikeln - Google Patents

Verfahren zur freisetzung von antibiotica aus antibioticahaltigen kunststoffpartikeln

Info

Publication number
DD133521A5
DD133521A5 DD7700201977A DD20197777A DD133521A5 DD 133521 A5 DD133521 A5 DD 133521A5 DD 7700201977 A DD7700201977 A DD 7700201977A DD 20197777 A DD20197777 A DD 20197777A DD 133521 A5 DD133521 A5 DD 133521A5
Authority
DD
German Democratic Republic
Prior art keywords
antibiotica
release
plastic particles
containing plastic
particles
Prior art date
Application number
DD7700201977A
Other languages
German (de)
English (en)
Inventor
Dietrich Heusser
Elvira Dingeldein
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2651441A external-priority patent/DE2651441C2/de
Priority claimed from DE19772727535 external-priority patent/DE2727535C2/de
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of DD133521A5 publication Critical patent/DD133521A5/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Composite Materials (AREA)
  • Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Surgical Instruments (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DD7700201977A 1976-11-11 1977-11-09 Verfahren zur freisetzung von antibiotica aus antibioticahaltigen kunststoffpartikeln DD133521A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2651441A DE2651441C2 (de) 1976-11-11 1976-11-11 Antibioticahaltiges Mittel
DE19772727535 DE2727535C2 (de) 1977-06-18 1977-06-18 Antibioticahaltiges Mittel

Publications (1)

Publication Number Publication Date
DD133521A5 true DD133521A5 (de) 1979-01-10

Family

ID=25771129

Family Applications (1)

Application Number Title Priority Date Filing Date
DD7700201977A DD133521A5 (de) 1976-11-11 1977-11-09 Verfahren zur freisetzung von antibiotica aus antibioticahaltigen kunststoffpartikeln

Country Status (22)

Country Link
US (2) US4191740A (da)
JP (1) JPS5366414A (da)
AR (1) AR216922A1 (da)
AT (1) AT359198B (da)
AU (1) AU518593B2 (da)
CA (1) CA1087984A (da)
CH (1) CH634228A5 (da)
DD (1) DD133521A5 (da)
DK (1) DK149301C (da)
ES (1) ES464067A1 (da)
FR (1) FR2370477A1 (da)
GB (1) GB1560017A (da)
HK (1) HK20782A (da)
IL (1) IL53325A0 (da)
IT (1) IT1091778B (da)
MX (1) MX6156E (da)
MY (1) MY8300030A (da)
NL (1) NL191080C (da)
NZ (1) NZ185650A (da)
PT (1) PT67214B (da)
SE (2) SE440448B (da)
YU (1) YU42924B (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2843963A1 (de) * 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
DE2807132C2 (de) * 1978-02-20 1983-11-03 Battelle-Institut E.V., 6000 Frankfurt Implantierbares Pharmaka-Depot
SU848004A1 (ru) * 1979-01-04 1981-07-23 Всесоюзный Научно-Исследовательскийи Испытательный Институт Медицинскойтехники Соединительный элемент дл фиксацииКОСТНОй ТКАНи
DE2905878A1 (de) * 1979-02-16 1980-08-28 Merck Patent Gmbh Implantationsmaterialien und verfahren zu ihrer herstellung
GB8331546D0 (en) * 1983-11-25 1984-01-04 Exxon Research Engineering Co Polymeric compositions
DE3513938A1 (de) * 1985-04-18 1986-10-23 Merck Patent Gmbh, 6100 Darmstadt Cytostatikahaltiges pharmakadepot
US4593073A (en) * 1985-04-23 1986-06-03 The Royal Institution For The Advancement Of Learing (Mcgill Univ.) Polymer resins with amino acid containing pendants for sorption of bile pigments and bile acids
DE3542972A1 (de) * 1985-12-05 1987-06-11 Merck Patent Gmbh Pharmakadepot
DE3613213A1 (de) * 1986-04-18 1987-10-22 Merck Patent Gmbh Tricalciumphosphat fuer implantationsmaterialien
US4778471A (en) * 1986-11-19 1988-10-18 University Of Dayton Zcap ceramics
JPH0794394B2 (ja) * 1986-12-24 1995-10-11 前田薬品工業株式会社 消炎鎮痛外用貼付剤
US4900546A (en) * 1987-07-30 1990-02-13 Pfizer Hospital Products Group, Inc. Bone cement for sustained release of substances
DE4019617A1 (de) * 1990-06-20 1992-01-02 Thera Ges Fuer Patente Implantierbares wirkstoffdepotmaterial
US5123927A (en) * 1990-12-05 1992-06-23 University Of British Columbia Method and apparatus for antibiotic knee prothesis
ES2068769B1 (es) * 1993-09-29 1995-11-16 Univ Santiago Compostela Procedimiento de obtencion de biomateriales implantables compuestos de ceramicas y antibioticos.
US6155812A (en) * 1998-07-15 2000-12-05 Biomet, Inc Cement mold for a temporary implant
US6361731B1 (en) 1998-07-15 2002-03-26 Biomet, Inc. Method of forming a temporary implant
DE10114364A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Verfahren zur Herstellung von antibiotischen Kompositen
DE10114244A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung
DE10114245A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung
US20050278023A1 (en) * 2004-06-10 2005-12-15 Zwirkoski Paul A Method and apparatus for filling a cavity
US20060265077A1 (en) * 2005-02-23 2006-11-23 Zwirkoski Paul A Spinal repair
WO2007056667A2 (en) * 2005-11-04 2007-05-18 Rush University Medical Center Plastic implant impregnated with an antibiotic
CN101365455A (zh) * 2005-12-15 2009-02-11 活跃生物药物学有限公司 利福霉素的用法
WO2007089739A2 (en) 2006-01-27 2007-08-09 Stryker Corporation Low pressure delivery system and method for delivering a solid and liquid mixture into a target site for medical treatment
DE102006006510A1 (de) * 2006-02-10 2007-08-23 Heraeus Kulzer Gmbh Lokales Wirkstofffreisetzungssystem und ein Verfahren zu seiner Herstellung
US7981945B2 (en) * 2006-03-01 2011-07-19 Poly-Med, Inc. Antimicrobial, radiopaque, microfiber-reinforced, polymeric methacrylate bone cement
US8685421B2 (en) 2006-07-07 2014-04-01 Surmodics, Inc. Beaded wound spacer device
EP1985317B1 (de) 2007-04-24 2013-06-05 Heraeus Kulzer GmbH Spacer-Polymethylmethacrylat-Knochenzement
DE102007063613B4 (de) 2007-04-24 2010-01-07 Heraeus Kulzer Gmbh Verwendung eines Spacer-Polymethylmethacrylat-Knochenzement
DE102007029098B4 (de) 2007-04-24 2010-12-09 Heraeus Kulzer Gmbh Spacer-Polymethylmethacrylat-Knochenzement und seine Verwendung
EP2288312B1 (en) 2007-12-07 2016-09-28 Zimmer Orthopaedic Surgical Products, Inc. Spacer molds and methods therefor
US8206143B2 (en) * 2007-12-13 2012-06-26 Biomet Manufacturing Corp. Modular articulating cement spacer
US20090202609A1 (en) * 2008-01-06 2009-08-13 Keough Steven J Medical device with coating composition
CN102548510B (zh) 2008-10-29 2015-04-01 捷迈骨科手术产品公司 具有可拆卸固定件的间隔件模具
DE102010020940B4 (de) * 2010-05-19 2014-09-25 Heraeus Medical Gmbh Antibiotische Beschichtung
DE102012006454A1 (de) 2012-03-30 2013-10-02 Heraeus Medical Gmbh Antiinfektiver Abstandshalter für Osteosyntheseplatten
JP6298468B2 (ja) 2012-10-16 2018-03-20 サーモディクス，インコーポレイテッド 創傷充填デバイスおよび方法
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface
ES2566232B2 (es) * 2014-10-09 2016-11-07 Lvd Biotech S.L. Formulaciones de cementos óseos con acción antibiótica
DE102015102210A1 (de) * 2015-02-16 2016-08-18 Heraeus Medical Gmbh Antimykotischer polymerisierbarer Knochenzement und ein Verfahren zu seiner Herstellung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2430740A (en) * 1942-08-29 1947-11-11 Arthur E Sharples Therapeutic dressing
CA935092A (en) * 1968-09-03 1973-10-09 S. Banker Gilbert Molecular drug entrapment process and compositions
US3868447A (en) * 1972-02-02 1975-02-25 Nat Patent Dev Corp Hema paste
US3955566A (en) * 1973-01-08 1976-05-11 Stoffey Donald G System and method for rigid enclosures
GB1468172A (en) * 1973-03-28 1977-03-23 Benzon As Alfred Oral drug preparations
DE2511122B2 (de) * 1975-03-14 1977-06-08 Vorprodukt fuer die zubereitung von knochenzement
CH611150A5 (da) * 1975-04-18 1979-05-31 Sulzer Ag

Also Published As

Publication number Publication date
DK149301C (da) 1986-09-01
MY8300030A (en) 1983-12-31
NZ185650A (en) 1979-11-01
GB1560017A (en) 1980-01-30
IT1091778B (it) 1985-07-06
AR216922A1 (es) 1980-02-15
SE8405922D0 (sv) 1984-11-23
PT67214A (de) 1977-11-01
FR2370477B1 (da) 1980-04-04
PT67214B (de) 1979-03-26
DK149301B (da) 1986-04-28
DK499577A (da) 1978-05-12
AU3053477A (en) 1979-05-17
CH634228A5 (de) 1983-01-31
AU518593B2 (en) 1981-10-08
MX6156E (es) 1984-11-29
AT359198B (de) 1980-10-27
NL191080B (nl) 1994-08-16
SE7712724L (sv) 1978-05-12
ATA803877A (de) 1980-03-15
SE440448B (sv) 1985-08-05
NL191080C (nl) 1995-01-16
YU268577A (en) 1984-02-29
US4233287A (en) 1980-11-11
JPS615450B2 (da) 1986-02-18
YU42924B (en) 1989-02-28
NL7712448A (nl) 1978-05-16
FR2370477A1 (fr) 1978-06-09
ES464067A1 (es) 1979-01-01
SE459846B (sv) 1989-08-14
JPS5366414A (en) 1978-06-13
CA1087984A (en) 1980-10-21
IL53325A0 (en) 1978-01-31
HK20782A (en) 1982-05-21
US4191740A (en) 1980-03-04
SE8405922L (sv) 1984-11-23

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