CZ290464B6 - 3-Substituované 3,4-dihydrothieno[2,3-d]pyrimidinové deriváty, jejich příprava a pouľití - Google Patents

3-Substituované 3,4-dihydrothieno[2,3-d]pyrimidinové deriváty, jejich příprava a pouľití Download PDF

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Publication number
CZ290464B6
CZ290464B6 CZ19994431A CZ443199A CZ290464B6 CZ 290464 B6 CZ290464 B6 CZ 290464B6 CZ 19994431 A CZ19994431 A CZ 19994431A CZ 443199 A CZ443199 A CZ 443199A CZ 290464 B6 CZ290464 B6 CZ 290464B6
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CZ
Czechia
Prior art keywords
groups
atom
methyl
chi2
pyrimidin
Prior art date
Application number
CZ19994431A
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Czech (cs)
English (en)
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CZ443199A3 (cs
Inventor
Gerd Steiner
Uta Dullweber
Dorothea Starck
Alfred Bach
Karsten Wicke
Hans-Jürgen Teschendorf
Francisco-Javier Garcia-Ladona
Franz Emling
Original Assignee
Basf Aktiengesellschaft
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Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of CZ443199A3 publication Critical patent/CZ443199A3/cs
Publication of CZ290464B6 publication Critical patent/CZ290464B6/cs

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CZ19994431A 1997-06-13 1998-05-29 3-Substituované 3,4-dihydrothieno[2,3-d]pyrimidinové deriváty, jejich příprava a pouľití CZ290464B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19724980A DE19724980A1 (de) 1997-06-13 1997-06-13 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung

Publications (2)

Publication Number Publication Date
CZ443199A3 CZ443199A3 (cs) 2000-06-14
CZ290464B6 true CZ290464B6 (cs) 2002-07-17

Family

ID=7832352

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ19994431A CZ290464B6 (cs) 1997-06-13 1998-05-29 3-Substituované 3,4-dihydrothieno[2,3-d]pyrimidinové deriváty, jejich příprava a pouľití

Country Status (25)

Country Link
US (1) US6159962A (de)
EP (1) EP0988306B1 (de)
JP (1) JP2002504103A (de)
KR (1) KR20010013696A (de)
CN (1) CN1260797A (de)
AR (1) AR015712A1 (de)
AT (1) ATE244720T1 (de)
AU (1) AU749320B2 (de)
BG (1) BG103900A (de)
BR (1) BR9810017A (de)
CA (1) CA2293816A1 (de)
CO (1) CO4940507A1 (de)
CZ (1) CZ290464B6 (de)
DE (2) DE19724980A1 (de)
HR (1) HRP980319A2 (de)
HU (1) HUP0002902A3 (de)
ID (1) ID23421A (de)
IL (1) IL132967A0 (de)
NO (1) NO996043L (de)
NZ (1) NZ502238A (de)
PL (1) PL337453A1 (de)
SK (1) SK168499A3 (de)
TR (1) TR199903062T2 (de)
WO (1) WO1998056792A1 (de)
ZA (1) ZA985121B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE491689T1 (de) * 1997-10-27 2011-01-15 Neurosearch As Heteroaryl diazacycloalkane als cholinergische ligande für nikotin-acetylcholin-rezeptoren
DE19900545A1 (de) * 1999-01-11 2000-07-13 Basf Ag Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie
EP1266898A4 (de) * 2000-02-29 2003-05-21 Takeda Chemical Industries Ltd Verfahren zur produktion von thienopyrimidinderivaten
DE10031389A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
US20050222175A1 (en) * 2004-03-31 2005-10-06 Dhanoa Dale S New piperidinylamino-thieno[2,3-D] pyrimidine compounds
US7612078B2 (en) * 2003-03-31 2009-11-03 Epix Delaware, Inc. Piperidinylamino-thieno[2,3-D] pyrimidine compounds
BRPI0408988A (pt) * 2003-03-31 2006-03-28 Predix Pharmaceuticals Holding composto de piperidinilamino-tieno[2,3-d]pirimidina
US7488736B2 (en) * 2004-05-17 2009-02-10 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7598265B2 (en) * 2004-09-30 2009-10-06 Epix Delaware, Inc. Compositions and methods for treating CNS disorders
US7407966B2 (en) * 2004-10-07 2008-08-05 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7576211B2 (en) * 2004-09-30 2009-08-18 Epix Delaware, Inc. Synthesis of thienopyridinone compounds and related intermediates
US8349850B2 (en) 2006-03-28 2013-01-08 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
EP2896624B1 (de) * 2007-03-28 2016-07-13 Atir Holding S.A. Heterotricyclische Verbindungen als Serotonerge und/oder Dopaminerge Mittel und Anwendungen davon
WO2008138126A1 (en) * 2007-05-09 2008-11-20 Neuromed Pharmaceuticals Ltd. Bicyclic pyrimidine derivatives as calcium channel blockers
US8114894B2 (en) * 2008-12-03 2012-02-14 Nanotherapeutics, Inc. Bicyclic compounds and methods of making and using same
WO2011024873A1 (ja) * 2009-08-26 2011-03-03 武田薬品工業株式会社 縮合複素環誘導体およびその用途
CA2832822A1 (en) 2011-04-10 2012-10-18 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
US9671052B2 (en) 2015-10-27 2017-06-06 Whirlpool Corporation Collet securing device for joining two fluid lines and providing lateral support at the connection of the two fluid lines
US10557469B2 (en) 2016-03-22 2020-02-11 Whirlpool Corporation Multi-outlet fluid flow system for an appliance incorporating a bi-directional motor
US10655266B2 (en) 2016-11-30 2020-05-19 Whirlpool Corporation Lint processing fluid pump for a laundry appliance
US10619289B2 (en) 2017-02-27 2020-04-14 Whirlpool Corporation Self cleaning diverter valve
US10662574B2 (en) 2017-02-27 2020-05-26 Whirlpool Corporation Self cleaning heater exchanger plate
US10480117B2 (en) 2017-02-27 2019-11-19 Whirlpool Corporation Self cleaning sump cover
US10634412B2 (en) 2017-04-10 2020-04-28 Whirlpool Corporation Concealed upstream air tower guide vanes
WO2020183011A1 (en) 2019-03-14 2020-09-17 Institut Curie Htr1d inhibitors and uses thereof in the treatment of cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4835157A (en) * 1988-03-15 1989-05-30 Ortho Pharmaceutical Corporation Thieno- and furopyrimidine-2,4-dione piperidine derivatives as serotonin antagonists and alpha adrenergic blocking agents
DE19636769A1 (de) * 1996-09-10 1998-03-12 Basf Ag 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
HUP0002902A3 (en) 2002-09-30
EP0988306B1 (de) 2003-07-09
HUP0002902A2 (hu) 2001-02-28
BR9810017A (pt) 2000-09-19
CO4940507A1 (es) 2000-07-24
AR015712A1 (es) 2001-05-16
KR20010013696A (ko) 2001-02-26
BG103900A (en) 2000-06-30
NO996043D0 (no) 1999-12-08
AU7917698A (en) 1998-12-30
ID23421A (id) 2000-04-20
US6159962A (en) 2000-12-12
JP2002504103A (ja) 2002-02-05
HRP980319A2 (en) 1999-04-30
CZ443199A3 (cs) 2000-06-14
EP0988306A1 (de) 2000-03-29
CN1260797A (zh) 2000-07-19
DE59808992D1 (de) 2003-08-14
NZ502238A (en) 2001-02-23
PL337453A1 (en) 2000-08-14
IL132967A0 (en) 2001-03-19
ATE244720T1 (de) 2003-07-15
WO1998056792A1 (de) 1998-12-17
TR199903062T2 (xx) 2000-06-21
ZA985121B (en) 1999-12-13
SK168499A3 (en) 2000-05-16
AU749320B2 (en) 2002-06-20
CA2293816A1 (en) 1998-12-17
DE19724980A1 (de) 1998-12-17
NO996043L (no) 1999-12-08

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Legal Events

Date Code Title Description
PD00 Pending as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 19980529