CY727A - New n-substituted lactams - Google Patents

New n-substituted lactams

Info

Publication number
CY727A
CY727A CY72774A CY72774A CY727A CY 727 A CY727 A CY 727A CY 72774 A CY72774 A CY 72774A CY 72774 A CY72774 A CY 72774A CY 727 A CY727 A CY 727A
Authority
CY
Cyprus
Prior art keywords
new
substituted lactams
lactams
substituted
Prior art date
Application number
CY72774A
Other languages
English (en)
Inventor
Joseph Honore Lucien M Strubbe
Raymond Armand Linz
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB697870A external-priority patent/GB1309692A/en
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of CY727A publication Critical patent/CY727A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
CY72774A 1964-08-06 1974-03-01 New n-substituted lactams CY727A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB32037/64A GB1039113A (en) 1964-08-06 1964-08-06 New n-substituted lactams
GB697870A GB1309692A (en) 1970-02-13 1970-02-13 N-substituted lactams

Publications (1)

Publication Number Publication Date
CY727A true CY727A (en) 1974-03-01

Family

ID=10332139

Family Applications (1)

Application Number Title Priority Date Filing Date
CY72774A CY727A (en) 1964-08-06 1974-03-01 New n-substituted lactams

Country Status (15)

Country Link
US (1) US3459738A (de)
AT (2) AT261599B (de)
BE (1) BE667906A (de)
CH (1) CH436304A (de)
CY (1) CY727A (de)
DE (1) DE1620608C3 (de)
DK (1) DK121174B (de)
ES (1) ES316156A1 (de)
FI (1) FI45446C (de)
FR (2) FR1478349A (de)
GB (1) GB1039113A (de)
IL (1) IL24082A (de)
IT (1) IT1052776B (de)
NL (1) NL148313B (de)
SE (1) SE308526B (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1309692A (en) * 1970-02-13 1973-03-14 Ucb Sa N-substituted lactams
FR2059985A1 (en) * 1969-08-29 1971-06-11 Synthelabo 4-benzyl piperidine 2,6-dione derivs
US4081456A (en) * 1973-02-28 1978-03-28 Mobil Oil Corporation Bis-lactam derivatives
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
AT360980B (de) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works Verfahren zur herstellung von n-alkylamiden des 2-oxo-1-pyrrolidins
US4069336A (en) * 1976-02-25 1978-01-17 Chemisches Laboratorium Fritz-Walter Lange Gmbh & Co Kg (2-oxo-pyrrolidines)-acetic hydrazides
GB1583871A (en) * 1976-10-19 1981-02-04 Ucb Sa Anti-aggregants
GB1539817A (en) * 1976-10-22 1979-02-07 Ucb Sa N-substituted lactams
GB1582351A (en) * 1977-02-10 1981-01-07 Ucb Sa Disubstituted ureas and thioureas
DE2757680A1 (de) * 1977-12-23 1979-06-28 Troponwerke Gmbh & Co Kg Neue 2-oxo-1-pyrrolidinessigsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CA1115212A (en) 1978-02-10 1981-12-29 Emilio Kyburz Pyrrolidine derivatives
DE2960194D1 (en) 1978-05-08 1981-04-16 Ucb Sa Lactam-n-acetic acids, their amides, process for their preparation and therapeutic compositions containing them
IT1141287B (it) * 1979-06-13 1986-10-01 Nattermann A & Cie Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
DE2924011C2 (de) 1979-06-13 1982-04-08 A. Nattermann & Cie GmbH, 5000 Köln Pyrrolidin-(2)-on-(1)-ylessigsäure-2,6,-dimethylanilid, Verfahren zur Herstellung und Arzneimittel, welche diese Verbindung enthalten
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
EP0089900B1 (de) * 1982-03-24 1985-12-27 Prodes S.A. N-((2-oxo-1-pyrrolidinyl)acetyl)Piperazine, Verfahren zu ihrer Herstellung sowie ihre Salze und ihre Verwendung in pharmazeutischen Zubereitungen
US4525476A (en) * 1983-05-26 1985-06-25 Warner-Lambert Company N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids and derivatives as cognition activators
DE3326724A1 (de) * 1983-07-25 1985-02-07 Boehringer Ingelheim KG, 6507 Ingelheim In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3420193A1 (de) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel
FI83510C (fi) * 1985-02-22 1991-07-25 Ciba Geigy Ag Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara bi-2h- pyrroli(di)ndioner.
PH23078A (en) * 1986-01-30 1989-04-10 Ciba Geigy Ag Substituted pyrrolidinones
IT1224168B (it) * 1986-08-01 1990-09-26 Finanziaria R F Spa Ora Finanz Derivati del pirrolidin-2-one ad attivita' nootropa
US4990513A (en) * 1987-02-06 1991-02-05 S O "Pharmachim" Antihypoxic drug and method of its application
JPH02500365A (ja) * 1987-05-20 1990-02-08 ザムボン　グループ　エス．ピー．エー． 認識補助作用を持つ化合物
JPS6422883A (en) * 1987-07-17 1989-01-25 Sanwa Kagaku Kenkyusho Co 1-pyrrolidine acetamide derivative, its salt, production thereof and prophylactic and remedial agent for cereral dysfunction containing said derivative and salt as active ingredient
JP2660201B2 (ja) * 1988-08-05 1997-10-08 塩野義製薬株式会社 新規ピロロ［１，４］ベンゾジアゼピン誘導体および老人性痴呆薬
CA2098663A1 (en) * 1992-06-19 1993-12-20 Shinji Kamihara Process for preparing pyrrolidinylacetamide derivative
CN1041630C (zh) * 1994-01-13 1999-01-13 北京大学 合成α-吡咯烷酮乙酰胺的方法
US5912189A (en) * 1998-05-12 1999-06-15 The Lubrizol Corporation Compositions containing reaction product of a cyclic compound containing both a nitrogen atom and a carbonyl group, an aldehyde or ketone, and an etheramine
GB0004297D0 (en) 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
DE60138733D1 (de) * 2000-12-28 2009-06-25 Hamilton Pharmaceuticals Inc Arzneimittel zur behandlung und vermeidung neurogener schmerzen
TR201820411T4 (tr) 2008-02-29 2019-01-21 Biolab Sanus Farmaceutica Ltda Rasetam ve karnitin içeren farmasötik bileşim ve bunun hazırlanış süreci.
JP5917148B2 (ja) 2008-10-16 2016-05-11 ザ ジョーンズ ホプキンズ ユニバーシティＴｈｅ Ｊｏｈｎｓ Ｈｏｐｋｉｎｓ Ｕｎｉｖｅｒｓｉｔｙ 認知機能を改善するための方法および組成物
PL389364A1 (pl) 2009-10-23 2011-04-26 Uniwersytet Jagielloński Nowe zastosowanie pochodnych 2-pirolidonu
EP2533645B1 (de) 2010-02-09 2016-07-27 The Johns Hopkins University Verfahren und zusammensetzungen zur verbesserung von kognitiven funktionen
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
EP2968220B1 (de) 2013-03-15 2021-05-05 Agenebio, Inc. Verfahren und zusammensetzungen zur verbesserung von kognitiven funktionen
US10806717B2 (en) 2013-03-15 2020-10-20 The Johns Hopkins University Methods and compositions for improving cognitive function
EA201891617A3 (ru) 2014-01-21 2019-04-30 Янссен Фармацевтика Нв Комбинации, содержащие положительные аллостерические модуляторы или ортостерические агонисты метаботропного глутаматергического рецептора 2 подтипа, и их применение
HUE053734T2 (hu) 2014-01-21 2021-07-28 Janssen Pharmaceutica Nv 2-es altípusú metabotróp glutamáterg receptor pozitív allosztérikus modulátorait tartalmazó kombinációk és alkalmazásuk
CN110072521B (zh) 2016-12-16 2022-11-29 爱杜西亚药品有限公司 包含t型钙通道阻断剂的药物组合
EA037205B1 (ru) * 2019-05-20 2021-02-19 Дмитрий Сергеевич Валуев Способ получения 2-(2-оксопирролидин-1-ил)-n-фенилацетамида
WO2024039886A1 (en) 2022-08-19 2024-02-22 Agenebio, Inc. Benzazepine derivatives, compositions, and methods for treating cognitive impairment

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE592979A (de) * 1959-07-14
US3185678A (en) * 1961-08-04 1965-05-25 Colgate Palmolive Co Polymethyleniminoalkylamides
US3250784A (en) * 1963-12-23 1966-05-10 Gen Aniline & Film Corp Pyrrolidonyl-gamma-butyramide and process of preparing

Also Published As

Publication number Publication date
AT258260B (de) 1967-11-10
AT261599B (de) 1968-05-10
IL24082A (en) 1969-02-27
SE308526B (de) 1969-02-17
IT1052776B (it) 1981-07-20
NL148313B (nl) 1976-01-15
DE1620608A1 (de) 1970-04-30
NL6509994A (de) 1966-02-07
FI45446B (de) 1972-02-29
FR1478349A (fr) 1967-04-28
DK121174B (da) 1971-09-20
ES316156A1 (es) 1965-11-16
BE667906A (de) 1966-02-07
DE1620608C3 (de) 1975-09-25
GB1039113A (en) 1966-08-17
FI45446C (fi) 1972-06-12
DE1620608B2 (de) 1975-01-30
CH436304A (fr) 1967-05-31
FR7119M (de) 1969-07-21
US3459738A (en) 1969-08-05

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