CY544A - 17beta -Monoesters of 11,17,21-trihydroxy steroid compounds - Google Patents

17beta -Monoesters of 11,17,21-trihydroxy steroid compounds

Info

Publication number
CY544A
CY544A CY54470A CY54470A CY544A CY 544 A CY544 A CY 544A CY 54470 A CY54470 A CY 54470A CY 54470 A CY54470 A CY 54470A CY 544 A CY544 A CY 544A
Authority
CY
Cyprus
Prior art keywords
17beta
monoesters
steroid compounds
trihydroxy steroid
trihydroxy
Prior art date
Application number
CY54470A
Other languages
English (en)
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of CY544A publication Critical patent/CY544A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Insulated Conductors (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Combinations Of Kitchen Furniture (AREA)
CY54470A 1963-06-11 1970-07-02 17beta -Monoesters of 11,17,21-trihydroxy steroid compounds CY544A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB23223/63A GB1047518A (en) 1963-06-11 1963-06-11 17ª‡-monoesters of 11,17,21-trihydroxy steroid compounds
GB362364 1964-01-28

Publications (1)

Publication Number Publication Date
CY544A true CY544A (en) 1970-07-02

Family

ID=26238483

Family Applications (1)

Application Number Title Priority Date Filing Date
CY54470A CY544A (en) 1963-06-11 1970-07-02 17beta -Monoesters of 11,17,21-trihydroxy steroid compounds

Country Status (14)

Country Link
US (1) US3312590A (forum.php)
BE (2) BE649170A (forum.php)
BR (2) BR6459936D0 (forum.php)
CH (2) CH450410A (forum.php)
CY (1) CY544A (forum.php)
DE (2) DE1443958B1 (forum.php)
DK (2) DK116205B (forum.php)
ES (2) ES300814A1 (forum.php)
FR (1) FR4548M (forum.php)
GB (1) GB1047518A (forum.php)
MY (1) MY7000131A (forum.php)
NL (2) NL142157B (forum.php)
NO (2) NO125533B (forum.php)
SE (2) SE313562B (forum.php)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3475466A (en) * 1965-08-30 1969-10-28 Schering Corp Novel 17,21-diesters of 16alpha-methyl-9alpha,11beta-dichloro-1,4- pregnadienes
US3422193A (en) * 1966-08-11 1969-01-14 Schering Corp 17-mono esters of corticoids
IT1061787B (it) * 1967-03-01 1983-04-30 Vismara Francesco Spa Miglioramenti relativi alla preparazione di 17 benzoato di betametazone
GB1281689A (en) * 1968-10-14 1972-07-12 Glaxo Lab Ltd Steroid 21-phosphates
US3694471A (en) * 1970-06-08 1972-09-26 Warner Lambert Pharmaceutical 17-valerate ester of 6{60 ,9{60 -difluorohydrocortisone, its compositions and use as an anti-inflammatory agent
DK135267A (forum.php) * 1971-02-25
US3789121A (en) * 1971-11-26 1974-01-29 Warner Lambert Co 17{60 ,21-orthobutyrates of 6{60 , 9{60 -difluoro-hydrocortisone and 6{60 , 9{60 -difluoroprednisolone, compositions containing same and the use thereof as anti-inflammatory agents
GB1429184A (en) * 1972-04-20 1976-03-24 Allen & Hanburys Ltd Physically anti-inflammatory steroids for use in aerosols
US4044126A (en) * 1972-04-20 1977-08-23 Allen & Hanburys Limited Steroidal aerosol compositions and process for the preparation thereof
SE418294B (sv) * 1974-03-27 1981-05-18 Plurichemie Anstalt Sett att framstella en 16alfa- eller 16beta-9alfa-klor eller -fluorsteroidester
US4018918A (en) * 1975-05-20 1977-04-19 The Upjohn Company Topical clindamycin preparations
DE2645104C2 (de) * 1976-10-04 1986-04-24 Schering AG, 1000 Berlin und 4709 Bergkamen 11β-Hydroxy-1,4,8-pregnatrien-3,20-dion-Derivate und Verfahren zu ihrer Herstellung
US4070462A (en) * 1976-10-26 1978-01-24 Schering Corporation Steroid ointment
JPS6040439B2 (ja) * 1978-03-29 1985-09-11 大正製薬株式会社 ヒドロコルチゾン誘導体
EP0029151B1 (en) * 1979-11-16 1985-09-25 STEROSYNT Ltd. 6-alpha-fluoro-9-alpha-chloro-prednisolone-17,21 diesters, pharmaceutical compositions containing them and intermediates
US4350690A (en) * 1980-10-27 1982-09-21 Cressington Investments Ltd. Steroid composition
US4346086A (en) * 1981-06-09 1982-08-24 Beiersdorf Aktiengesellschaft Corticosteroid-containing cream
IL66432A0 (en) * 1981-08-04 1982-12-31 Plurichemie Anstalt Process for the preparation of steroidal esters
DE3133081A1 (de) * 1981-08-18 1983-03-10 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue 6(alpha)-methylprednisolon-derivate, ihre herstellung und verwendung
FR2515041A1 (fr) * 1981-10-26 1983-04-29 Besins Jean Medicament a base de progesterone pour le traitement des affections mammaires
EP0095894A3 (en) * 1982-05-31 1985-01-02 Ohta Seiyaku Kabushiki Kaisha. 6 alpha-methylprednisolone derivatives
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
DE3243482A1 (de) * 1982-11-22 1984-05-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6(alpha)-methylkortikoide, ihre herstellung und verwendung
US4482539A (en) * 1983-05-13 1984-11-13 Schering Corporation Betamethasone dipropionate cream
US4489070A (en) * 1983-05-13 1984-12-18 Schering Corporation Betamethasone dipropionate cream
DE3400188A1 (de) * 1984-01-02 1985-07-11 Schering AG, Berlin und Bergkamen, 1000 Berlin Neue 6(alpha),16(alpha)-dimethylkortikoide
PT78973A (en) * 1984-07-25 1984-08-01 Joao Emerico Villax New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid
UA26230A (uk) * 1990-03-02 1999-07-19 Глексо Груп Лімітед Іhгалятор для спільhого використаhhя з лікувальhим блоком і лікувальhий блок
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
SK280968B6 (sk) 1990-03-02 2000-10-09 Glaxo Group Limited Balenie medikamentu na použite v inhalačnom prístroji
US6777399B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
CA2417825C (en) * 2000-08-05 2008-07-22 Glaxo Group Limited 6.alpha., 9.alpha.-difluoro-17.alpha.-`(2-furanylcarboxyl)oxy!-11.beta.-hydroxy-16.alpha.-methyl-3-oxo-androst-1,4,-diene-17-carbothioic acid s-fluoromethyl ester as an anti-inflammatory agent
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
MY137522A (en) * 2001-04-30 2009-02-27 Glaxo Group Ltd Novel anti-inflammatory androstane derivatives.
WO2002100879A1 (en) * 2001-06-12 2002-12-19 Glaxo Group Limited Novel anti-inflammatory 17.alpha.-heterocyclic-esters of 17.beta.carbothioate androstane derivatives
WO2003048181A1 (en) * 2001-12-01 2003-06-12 Glaxo Group Limited 17.alpha. -cyclic esters of 16-methylpregnan-3,20-dione as anti-inflammatory agents
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) * 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
CA2537185A1 (en) * 2003-08-29 2005-03-10 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-iv
EP1694655A2 (en) * 2003-11-26 2006-08-30 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
US20080009535A1 (en) * 2004-08-30 2008-01-10 Sarala Balachandran Inhibitors of phosphodiesterase type-IV
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
WO2007031838A1 (en) 2005-09-16 2007-03-22 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
JP2009512676A (ja) 2005-10-19 2009-03-26 ランバクシー ラボラトリーズ リミテッド ムスカリン性受容体アンタゴニストの医薬組成物
US20090054382A1 (en) * 2005-10-19 2009-02-26 Abhijit Ray Compositions of phosphodiesterase type iv inhibitors
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
US20100029728A1 (en) * 2006-09-22 2010-02-04 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
AU2007298549A1 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-IV
EP1958947A1 (en) 2007-02-15 2008-08-20 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type 4
CN103497185A (zh) * 2007-03-14 2014-01-08 兰贝克赛实验室有限公司 用作磷酸二酯酶抑制剂的吡唑并(3,4-b)吡啶衍生物
EP2124943A1 (en) * 2007-03-14 2009-12-02 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b]pyridine derivatives as phosphodiesterase inhibitors
US8796248B2 (en) 2007-10-05 2014-08-05 Nektar Therapeutics Oligomer-corticosteroid conjugates
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
CN112358522B (zh) * 2020-05-18 2021-11-16 河南利华制药有限公司 一种倍他米松二丙酸酯的精制方法及倍他米松二丙酸酯
CN111944002A (zh) * 2020-07-29 2020-11-17 河南利华制药有限公司 一种倍氯米松二丙酸酯中间体及制备方法
CN116023425B (zh) * 2023-03-28 2023-06-20 南京师范大学 曲安西龙衍生物及其医药用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3147249A (en) * 1961-06-13 1964-09-01 Vismara Francesco Spa 17alpha, 21-substituted methylenedioxy steroids and methods therefor
CH429716A (de) * 1961-06-24 1967-02-15 Vismara Francesco Spa Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden
DE1214677B (de) * 1961-06-24 1966-04-21 Vismara Francesco Spa Verfahren zur Herstellung von 17alpha-Acyloxy-21-hydroxysteroiden

Also Published As

Publication number Publication date
CH450410A (de) 1968-01-31
SE313562B (forum.php) 1969-08-18
NL6406614A (forum.php) 1964-12-14
MY7000131A (en) 1970-12-31
FR4548M (forum.php) 1966-11-02
BE649171A (forum.php) 1964-12-11
DK116128B (da) 1969-12-15
BR6459937D0 (pt) 1973-08-07
NL142157B (nl) 1974-05-15
DK116205B (da) 1969-12-22
NO125532B (forum.php) 1972-09-25
BR6459936D0 (pt) 1973-08-02
NO125533B (forum.php) 1972-09-25
DE1443958B1 (de) 1970-01-02
DE1443957B1 (de) 1970-01-02
NL6406615A (forum.php) 1964-12-14
US3312590A (en) 1967-04-04
ES300814A1 (es) 1964-12-01
ES300811A1 (es) 1962-12-16
BE649170A (forum.php) 1964-12-11
SE320066B (forum.php) 1970-02-02
NL141378B (nl) 1974-03-15
CH457422A (de) 1968-06-15
GB1047518A (en) 1966-11-02

Similar Documents

Publication Publication Date Title
CY544A (en) 17beta -Monoesters of 11,17,21-trihydroxy steroid compounds
CA668494A (en) Preparation of 3,3,3-trifluoropropene
CY545A (en) 17beta, 21-Diesters of 11,17,21-trihydroxy steroid compounds
CA659441A (en) Substituted hydrazide compounds
AU291165B2 (en) 17a-MONOESTERS OF 11, 17, 21-TRIHYDROXY STEROID COMPOUNDS
MY7000132A (en) 17 alpha 21- deisters of 11,17,21- trihydroxy steroid compounds
CA638759A (en) Process of preventing the formation of emulsions
AU4547464A (en) 17a-MONOESTERS OF 11, 17, 21-TRIHYDROXY STEROID COMPOUNDS
CA659752A (en) Plastisol composition
CA656755A (en) 9.alpha.-HYDROXYLATION OF STEROIDS
AU286800B2 (en) Steroid 2 acetamido -2 - deoxy - glucosides and - galactosides
CA981273A (en) Lead compounds of 4:6-dinitroresorcinol
IL21455A (en) Derivatives of 5,10-epoxy-dibenzocycloheptenes
AU295157B2 (en) 17, 21-diesters of 11, 17, 21-trihydroxy steroids
AU4102464A (en) Steroid 2 acetamido -2 - deoxy - glucosides and - galactosides
AU266804B2 (en) Preparation of 3, 4-dimethyl-8-nitroquinoline
AU287213B2 (en) Preparation of 1, 2-epoxyperfluoroalkanes
CA660626A (en) Preparation of 2,6-diethylpiperazine
AU266105B2 (en) PREPARATION OF l, 2, 3, 4-TETRAHYDRO-5-ACRIDONE
AU284865B2 (en) 10 or 11 - halo derivatives of dibenzocyclo heptene
CA663281A (en) Process for the manufacture of cyclodecanol-(1) one(6)
CA667483A (en) Process for the manufacture of cyclodecanol-(1)one(6)
AU283494B2 (en) 2 - oximino - 3 - keto - 17 - oxygenatedd steroids of the androstatne series
AU290200B2 (en) Preparation of steroidal 19 - nor - 3 - hydroxy - 1,3,5 (10) - trienes
IE27925L (en) Steroid compounds