CY1121414T1 - Παρασκευη ιικου φορεα - Google Patents
Παρασκευη ιικου φορεαInfo
- Publication number
- CY1121414T1 CY1121414T1 CY20181100533T CY181100533T CY1121414T1 CY 1121414 T1 CY1121414 T1 CY 1121414T1 CY 20181100533 T CY20181100533 T CY 20181100533T CY 181100533 T CY181100533 T CY 181100533T CY 1121414 T1 CY1121414 T1 CY 1121414T1
- Authority
- CY
- Cyprus
- Prior art keywords
- virus
- modified
- cell
- operator
- production
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 3
- 101150016130 CP77 gene Proteins 0.000 abstract 1
- 101100372716 Escherichia phage 186 fil gene Proteins 0.000 abstract 1
- 241000700647 Variola virus Species 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24151—Methods of production or purification of viral material
- C12N2710/24152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Η παρούσα εφεύρεση αναφέρεται σ' ένα τροποποιημένο θηλαστικό κύτταρο όπου το γονιδίωμα του κυττάρου τροποποιείται για να περιλαμβάνει μία αλληλουχία που κωδικοποιεί το CP77 υπό τον έλεγχο ενός υποκινητή, έτσι ώστε η τροποποιημένη κυτταρική σειρά να διατηρεί τον πολλαπλασιασμό ενός ιού ευλογιάς, που να είναι λιγότερο ικανός ή ανίκανος να πολλαπλασιάζεται στο μη τροποποιημένο κύτταρο.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013904242A AU2013904242A0 (en) | 2013-11-01 | Viral vector manufacture | |
| AU2014900370A AU2014900370A0 (en) | 2014-02-07 | Orthopox vectors and propagation | |
| PCT/AU2014/050330 WO2015061858A1 (en) | 2013-11-01 | 2014-11-03 | Viral vector manufacture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1121414T1 true CY1121414T1 (el) | 2020-05-29 |
Family
ID=53003022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20181100533T CY1121414T1 (el) | 2013-11-01 | 2018-05-22 | Παρασκευη ιικου φορεα |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US10544397B2 (el) |
| EP (2) | EP3375882B1 (el) |
| JP (2) | JP6682443B2 (el) |
| KR (1) | KR102047030B1 (el) |
| CN (1) | CN106255758B (el) |
| AU (1) | AU2014344738B2 (el) |
| CA (1) | CA2931518C (el) |
| CY (1) | CY1121414T1 (el) |
| DK (2) | DK3063278T3 (el) |
| ES (1) | ES2670034T3 (el) |
| HK (1) | HK1223395A1 (el) |
| HR (1) | HRP20180789T1 (el) |
| HU (1) | HUE037718T2 (el) |
| LT (1) | LT3063278T (el) |
| NO (1) | NO3063278T3 (el) |
| NZ (1) | NZ720241A (el) |
| PL (1) | PL3063278T3 (el) |
| PT (1) | PT3063278T (el) |
| RS (1) | RS57290B1 (el) |
| RU (1) | RU2658487C2 (el) |
| SG (1) | SG11201603919XA (el) |
| SI (1) | SI3063278T1 (el) |
| TR (1) | TR201807128T4 (el) |
| WO (1) | WO2015061858A1 (el) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109862909A (zh) * | 2016-08-19 | 2019-06-07 | 赛门蒂斯有限公司 | 病毒疫苗 |
| JP2018081568A (ja) * | 2016-11-17 | 2018-05-24 | グローリー株式会社 | 紙幣収納装置および紙幣処理機 |
| WO2024003346A1 (en) * | 2022-06-30 | 2024-01-04 | Bavarian Nordic A/S | Mammalian cell line for the production of modified vaccinia virus ankara (mva) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2604183B1 (fr) * | 1986-09-23 | 1988-12-30 | Transgene Sa | Sequence d'adn, vecteurs, virus recombinants et procede mettant en oeuvre des virus de la vaccine recombinants capables de se multiplier dans les cellules cho |
| AU694519B2 (en) | 1994-04-29 | 1998-07-23 | Immuno Aktiengesellschaft | Recombinant poxviruses with foreign polynucleotides in essential regions |
| CA2489301A1 (en) * | 2002-08-07 | 2004-02-19 | Bavarian Nordic A/S | Vaccinia virus host range genes to increase the titer of avipoxviruses |
| FR2884255B1 (fr) * | 2005-04-11 | 2010-11-05 | Vivalis | Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe |
| JP2009545309A (ja) * | 2006-08-04 | 2009-12-24 | ダブリン シティ ユニバーシティ | 組換え型生物学的製剤を製造する方法 |
-
2014
- 2014-11-03 SG SG11201603919XA patent/SG11201603919XA/en unknown
- 2014-11-03 CA CA2931518A patent/CA2931518C/en active Active
- 2014-11-03 PT PT148588023T patent/PT3063278T/pt unknown
- 2014-11-03 PL PL14858802T patent/PL3063278T3/pl unknown
- 2014-11-03 CN CN201480071836.9A patent/CN106255758B/zh active Active
- 2014-11-03 JP JP2016550897A patent/JP6682443B2/ja active Active
- 2014-11-03 RU RU2016121425A patent/RU2658487C2/ru active
- 2014-11-03 SI SI201430731T patent/SI3063278T1/sl unknown
- 2014-11-03 EP EP18154084.0A patent/EP3375882B1/en active Active
- 2014-11-03 NO NO14858802A patent/NO3063278T3/no unknown
- 2014-11-03 DK DK14858802.3T patent/DK3063278T3/en active
- 2014-11-03 US US15/033,541 patent/US10544397B2/en active Active
- 2014-11-03 LT LTEP14858802.3T patent/LT3063278T/lt unknown
- 2014-11-03 TR TR2018/07128T patent/TR201807128T4/tr unknown
- 2014-11-03 AU AU2014344738A patent/AU2014344738B2/en active Active
- 2014-11-03 DK DK18154084.0T patent/DK3375882T3/da active
- 2014-11-03 NZ NZ72024114A patent/NZ720241A/en unknown
- 2014-11-03 ES ES14858802.3T patent/ES2670034T3/es active Active
- 2014-11-03 KR KR1020167014693A patent/KR102047030B1/ko active IP Right Grant
- 2014-11-03 HU HUE14858802A patent/HUE037718T2/hu unknown
- 2014-11-03 EP EP14858802.3A patent/EP3063278B1/en active Active
- 2014-11-03 RS RS20180588A patent/RS57290B1/sr unknown
- 2014-11-03 WO PCT/AU2014/050330 patent/WO2015061858A1/en active Application Filing
-
2016
- 2016-10-04 HK HK16111526.2A patent/HK1223395A1/zh unknown
-
2018
- 2018-05-18 HR HRP20180789TT patent/HRP20180789T1/hr unknown
- 2018-05-22 CY CY20181100533T patent/CY1121414T1/el unknown
-
2019
- 2019-10-18 JP JP2019191435A patent/JP2020039340A/ja active Pending
- 2019-12-11 US US16/711,184 patent/US20200190482A1/en not_active Abandoned
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