CY1119689T1 - Μεθοδοι και συνθεσεις για την ανιχνευση του επιπεδου της δραστικοτητας της λυσοσωμικης εξωκυτταρωσης και μεθοδοι χρησης - Google Patents

Μεθοδοι και συνθεσεις για την ανιχνευση του επιπεδου της δραστικοτητας της λυσοσωμικης εξωκυτταρωσης και μεθοδοι χρησης

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Publication number
CY1119689T1
CY1119689T1 CY20171101321T CY171101321T CY1119689T1 CY 1119689 T1 CY1119689 T1 CY 1119689T1 CY 20171101321 T CY20171101321 T CY 20171101321T CY 171101321 T CY171101321 T CY 171101321T CY 1119689 T1 CY1119689 T1 CY 1119689T1
Authority
CY
Cyprus
Prior art keywords
methods
lysosomal
activity
disease
level
Prior art date
Application number
CY20171101321T
Other languages
Greek (el)
English (en)
Inventor
Ida ANNUNZIATA
Alessandra D’AZZO
Shai WHITE-GILBERTSON
Original Assignee
St. Jude Children's Research Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St. Jude Children's Research Hospital filed Critical St. Jude Children's Research Hospital
Publication of CY1119689T1 publication Critical patent/CY1119689T1/el

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    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4813—Exopeptidases (3.4.11. to 3.4.19)
    • A—HUMAN NECESSITIES
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01018—Exo-alpha-sialidase (3.2.1.18), i.e. trans-sialidase
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    • C12Y304/16—Serine-type carboxypeptidases (3.4.16)
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CY20171101321T 2011-08-31 2017-12-18 Μεθοδοι και συνθεσεις για την ανιχνευση του επιπεδου της δραστικοτητας της λυσοσωμικης εξωκυτταρωσης και μεθοδοι χρησης CY1119689T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161529675P 2011-08-31 2011-08-31
US201161544855P 2011-10-07 2011-10-07
PCT/US2012/052629 WO2013033074A2 (en) 2011-08-31 2012-08-28 Methods and compositions to detect the level of lysosomal exocytosis activity and methods of use

Publications (1)

Publication Number Publication Date
CY1119689T1 true CY1119689T1 (el) 2018-04-04

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EP (1) EP2751279B1 (cg-RX-API-DMAC7.html)
JP (1) JP6228121B2 (cg-RX-API-DMAC7.html)
AU (1) AU2012300252B2 (cg-RX-API-DMAC7.html)
CA (1) CA2847057C (cg-RX-API-DMAC7.html)
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TW201516020A (zh) 2013-09-06 2015-05-01 Xenoport Inc （ｎ，ｎ－二乙基胺甲醯基）甲基（２ｅ）丁－２－烯－１，４－二酸甲酯之晶形、合成方法及用途
US9999672B2 (en) 2014-03-24 2018-06-19 Xenoport, Inc. Pharmaceutical compositions of fumaric acid esters
WO2016179481A1 (en) * 2015-05-07 2016-11-10 Cardelli James Allen Cancer treatment via repositioned tricyclic anti-depressant-like drugs as anti-cancer agents and new combinations of such drugs
WO2017075540A1 (en) * 2015-10-30 2017-05-04 Ultragenyx Pharmaceutical Inc. Methods and compositions for the treatment of amyloidosis
WO2017161360A2 (en) * 2016-03-18 2017-09-21 Nant Holdings Ip, Llc Multimodal vector for dendritic cell infection
EP3366063B1 (en) * 2017-01-04 2020-03-04 Telefonaktiebolaget LM Ericsson (publ) Method, base station and user equipment for transceiving system information
JP7537762B2 (ja) 2019-07-05 2024-08-21 国立大学法人徳島大学 改変ノイラミニダーゼ
JP2025504704A (ja) * 2022-01-31 2025-02-14 センス リサーチ ファウンデーション 老化細胞表面マーカー

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