CY1117176T1 - Στερεο παρασκευασμα το οποιο περιλαμβανει πιογλιταζονη, γλιμεπιριδη και εναν εστερα λιπαρου οξεος πολυοξυαιθυλενο σορβιτανης - Google Patents

Στερεο παρασκευασμα το οποιο περιλαμβανει πιογλιταζονη, γλιμεπιριδη και εναν εστερα λιπαρου οξεος πολυοξυαιθυλενο σορβιτανης

Info

Publication number
CY1117176T1
CY1117176T1 CY20161100077T CY161100077T CY1117176T1 CY 1117176 T1 CY1117176 T1 CY 1117176T1 CY 20161100077 T CY20161100077 T CY 20161100077T CY 161100077 T CY161100077 T CY 161100077T CY 1117176 T1 CY1117176 T1 CY 1117176T1
Authority
CY
Cyprus
Prior art keywords
glimepiride
pioglitazone
fatty acid
solid preparation
acid polysaccharide
Prior art date
Application number
CY20161100077T
Other languages
English (en)
Inventor
Kazuhiro Doken
Tetsuya Kawano
Hiroyoshi Koyama
Naoru Hamaguchi
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34543966&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1117176(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of CY1117176T1 publication Critical patent/CY1117176T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Παρέχεται ένα στερεό παρασκεύασμα χρήσιμο ως παράγοντας θεραπείας του διαβήτη ή των παρόμοιων και εξαιρετικό ως προς τις ιδιότητες διάλυσης ενός ευαισθητοποιητή ινσουλίνης και ενός εκκριταγωγού ινσουλίνης, το οποίο περιλαμβάνει έναν ευαισθητοποιητή ινσουλίνης, ένα εκκριταγωγό ινσουλίνης και έναν εστέρα λιπαρού οξέος πολυοξυαιθυλενο σορβιτάνης.
CY20161100077T 2003-10-31 2016-01-28 Στερεο παρασκευασμα το οποιο περιλαμβανει πιογλιταζονη, γλιμεπιριδη και εναν εστερα λιπαρου οξεος πολυοξυαιθυλενο σορβιτανης CY1117176T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003371679 2003-10-31
EP04793070.6A EP1677792B1 (en) 2003-10-31 2004-10-21 Solid preparation comprising pioglitazone, glimepiride and a polyoxyethylene sorbitan fatty acid ester

Publications (1)

Publication Number Publication Date
CY1117176T1 true CY1117176T1 (el) 2017-04-05

Family

ID=34543966

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161100077T CY1117176T1 (el) 2003-10-31 2016-01-28 Στερεο παρασκευασμα το οποιο περιλαμβανει πιογλιταζονη, γλιμεπιριδη και εναν εστερα λιπαρου οξεος πολυοξυαιθυλενο σορβιτανης

Country Status (28)

Country Link
US (1) US7700128B2 (el)
EP (1) EP1677792B1 (el)
KR (2) KR100952090B1 (el)
CN (1) CN1874774B (el)
AR (1) AR046210A1 (el)
AU (1) AU2004285354B2 (el)
BR (1) BRPI0414979A (el)
CA (1) CA2540225C (el)
CY (1) CY1117176T1 (el)
DK (1) DK1677792T3 (el)
ES (1) ES2556244T3 (el)
GE (1) GEP20084570B (el)
HR (1) HRP20151447T1 (el)
HU (1) HUE028576T2 (el)
IL (1) IL174201A (el)
JO (1) JO3106B1 (el)
MA (1) MA28116A1 (el)
MX (1) MXPA06004639A (el)
NO (1) NO340294B1 (el)
NZ (1) NZ546337A (el)
PE (1) PE20050923A1 (el)
PL (1) PL1677792T3 (el)
PT (1) PT1677792E (el)
RU (1) RU2359661C2 (el)
SI (1) SI1677792T1 (el)
TW (1) TWI339586B (el)
WO (1) WO2005041962A1 (el)
ZA (1) ZA200602056B (el)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050220881A1 (en) * 2003-10-10 2005-10-06 Bvm Holding Co. Pharmaceutical composition
MXPA05013220A (es) * 2005-12-06 2007-06-05 Leopoldo De Jesus Espinosa Abdala Composiciones farmaceuticas que comprenden sustancias antidiabeticas combinadas para su uso en diabetes mellitus tipo 2.
RU2426530C2 (ru) * 2005-12-22 2011-08-20 Такеда Фармасьютикал Компани Лимитед Твердый препарат
KR101628028B1 (ko) * 2006-06-27 2016-06-08 다이이찌 산쿄 가부시키가이샤 압축 제제
JP5284968B2 (ja) * 2007-02-01 2013-09-11 武田薬品工業株式会社 アログリプチンおよびピオグリタゾンを含有する固形製剤
IS8660A (is) * 2007-07-02 2009-01-03 Actavis Group Ptc Ehf. Gliklasíð lyfjasamsetning
EP2190417A2 (en) * 2008-03-26 2010-06-02 Teva Pharmaceutical Industries Ltd. Pharmaceutical compositions comprising insulin sensitizer and insulin secretagogue
EP2374007A2 (en) 2008-12-04 2011-10-12 IKFE GmbH Biomarkers for atherosclerosis
EP2376926A1 (en) 2008-12-11 2011-10-19 IKFE GmbH Biomarkers for insulin sensitizer drug response
EP2382467A1 (en) 2008-12-30 2011-11-02 IKFE GmbH Biomarkers for adipose tissue activity
WO2010079428A2 (en) 2009-01-07 2010-07-15 Ikfe Gmbh Biomarkers for appetite regulation
WO2010107519A1 (en) * 2009-03-20 2010-09-23 Smartcells, Inc. Terminally-functionalized conjugates and uses thereof
EP2618827B1 (en) * 2010-09-21 2021-06-02 Intekrin Therapeutics, Inc. Antidiabetic solid pharmaceutical compositions
EP2438911A1 (en) * 2010-10-08 2012-04-11 LEK Pharmaceuticals d.d. Pharmaceuticals compositions comprising sulphonylurea-class insulin secretagogue and polyethylene glycol castor oil
WO2013034174A1 (en) * 2011-09-06 2013-03-14 ZENTIVA Saglik Ürünleri Sanayi ve Ticaret A.S. Solid preparations of pioglitazone and glimepiride
CN104288161A (zh) * 2014-09-19 2015-01-21 四川海思科制药有限公司 一种含吡格列酮格列美脲的药物组合物
KR20220070057A (ko) 2015-03-09 2022-05-27 인테크린 테라퓨틱스, 아이엔씨. 비알코올성 지방간 질환 및/또는 지방이영양증의 치료 방법
JP2020515639A (ja) 2017-04-03 2020-05-28 コヒラス・バイオサイエンシズ・インコーポレイテッド 進行性核上性麻痺の処置のためのＰＰＡＲγアゴニスト
US11992477B2 (en) 2018-05-31 2024-05-28 Hua Medicine (Shanghai) Ltd. Pharmaceutical combination, composition, and combination preparation comprising glucokinase activator and SGLT-2 inhibitor and preparation methods and uses thereof

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5865213A (ja) * 1981-10-13 1983-04-18 Tokai Kapuseru Kk ｄｌ−２−（４，８，１２−トリメチルトリデシル）−２，５，７，８−テトラメチル−６−クロマニルニコチネ−ト軟カプセル剤
US4620974A (en) * 1983-07-07 1986-11-04 American Home Products Corporation Pharmaceutical composition containing a liquid lubricant
JP2764274B2 (ja) * 1988-03-28 1998-06-11 株式会社ミドリ十字 医薬組成物
ATE198547T1 (de) * 1993-11-03 2001-01-15 Isomed Inc Mizelleförmige feinteilige pharmazeutische zusammensetzungen
HU212428B (en) * 1994-05-13 1996-06-28 Egyt Gyogyszervegyeszeti Gyar Process to prepare pharmaceutical compositions containing gemfibrozyl
TWI238064B (en) 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
CN1072649C (zh) 1995-09-13 2001-10-10 武田药品工业株式会社 苯并氧杂吖庚因化合物,其生产方法和用途
GB9619757D0 (en) * 1996-09-21 1996-11-06 Knoll Ag Chemical process
FR2758461A1 (fr) * 1997-01-17 1998-07-24 Pharma Pass Composition pharmaceutique presentant une biodisponibilite elevee et son procede de preparation
US5859037A (en) 1997-02-19 1999-01-12 Warner-Lambert Company Sulfonylurea-glitazone combinations for diabetes
US6011049A (en) 1997-02-19 2000-01-04 Warner-Lambert Company Combinations for diabetes
US6291495B1 (en) 1997-02-24 2001-09-18 Robert B. Rieveley Method and composition for the treatment of diabetes
US6025372A (en) 1997-04-04 2000-02-15 Merck & Co., Inc. Somatostatin agonists
US6057338A (en) 1997-04-04 2000-05-02 Merck & Co., Inc. Somatostatin agonists
CN1168451C (zh) 1997-06-18 2004-09-29 史密丝克莱恩比彻姆有限公司 噻唑烷二酮和磺酰脲组合物在制备治疗糖尿病的药物中的用途
GB9715306D0 (en) 1997-07-18 1997-09-24 Smithkline Beecham Plc Novel method of treatment
GB9715298D0 (en) 1997-07-18 1997-09-24 Smithkline Beecham Plc Novel method of treatment
GB9715295D0 (en) 1997-07-18 1997-09-24 Smithkline Beecham Plc Novel method of treatment
CN1277550A (zh) * 1997-09-11 2000-12-20 尼科梅德丹麦有限公司 非甾体抗炎药物(NSAIDs)的改进释放的复合型组合物
WO1999022735A1 (en) 1997-10-30 1999-05-14 Merck & Co., Inc. Somatostatin agonists
WO2000028989A1 (en) 1998-11-12 2000-05-25 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
AR035016A1 (es) 1999-08-25 2004-04-14 Takeda Chemical Industries Ltd Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima.
CA2386517A1 (en) 1999-10-07 2001-04-12 Takeda Chemical Industries, Ltd. Amine derivatives
US20030180352A1 (en) 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6793934B1 (en) 1999-12-08 2004-09-21 Shire Laboratories, Inc. Solid oral dosage form
US20010036479A1 (en) 2000-01-14 2001-11-01 Gillian Cave Glyburide composition
CA2407149C (en) 2000-04-28 2010-10-12 Takeda Chemical Industries, Ltd. Melanin-concentrating hormone antagonist
US6524621B2 (en) 2000-05-01 2003-02-25 Aeropharm Technology Inc. Core formulation
US7229986B2 (en) 2000-05-16 2007-06-12 Takeda Pharmaceutical Company Ltd. Melanin-concentrating hormone antagonist
EP1738751B1 (en) 2001-01-12 2011-05-11 Sun Pharma Advanced Research Company Ltd Spaced drug delivery system
WO2003042204A1 (fr) 2001-10-19 2003-05-22 Takeda Chemical Industries, Ltd. Derive d'amine
US6682759B2 (en) * 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
AU2003281181A1 (en) 2002-07-11 2004-02-02 Takeda Pharmaceutical Company Limited Process for producing coated preparation
UA80991C2 (en) 2002-10-07 2007-11-26 Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes
US20040147564A1 (en) 2003-01-29 2004-07-29 Rao Vinay U. Combinations of glimepiride and the thiazolidinedione for treatment of diabetes
EP1588708A4 (en) 2003-01-29 2006-03-01 Takeda Pharmaceutical METHOD FOR PRODUCING COATED PREPARATION
FR2853831A1 (fr) * 2003-03-05 2004-10-22 Usv Ltd Forme posologique solide a usage oral de metformine et de glyburide et son procede de preparation

Also Published As

Publication number Publication date
NZ546337A (en) 2009-03-31
JO3106B1 (ar) 2017-09-20
CN1874774A (zh) 2006-12-06
GEP20084570B (en) 2008-12-25
AU2004285354B2 (en) 2009-09-17
KR100952090B1 (ko) 2010-04-13
PT1677792E (pt) 2016-02-09
CA2540225C (en) 2012-03-06
NO340294B1 (no) 2017-03-27
PL1677792T3 (pl) 2016-05-31
DK1677792T3 (en) 2015-12-14
CA2540225A1 (en) 2005-05-12
RU2359661C2 (ru) 2009-06-27
AU2004285354A1 (en) 2005-05-12
PE20050923A1 (es) 2005-12-26
EP1677792A1 (en) 2006-07-12
NO20062515L (no) 2006-07-31
WO2005041962A1 (en) 2005-05-12
KR20060061383A (ko) 2006-06-07
CN1874774B (zh) 2011-04-13
HUE028576T2 (en) 2016-12-28
AR046210A1 (es) 2005-11-30
SI1677792T1 (sl) 2016-02-29
TW200524641A (en) 2005-08-01
US20060223870A1 (en) 2006-10-05
BRPI0414979A (pt) 2006-11-21
EP1677792B1 (en) 2015-11-18
IL174201A0 (en) 2006-08-01
HRP20151447T1 (hr) 2016-02-12
IL174201A (en) 2011-04-28
ES2556244T3 (es) 2016-01-14
RU2006118786A (ru) 2007-12-10
ZA200602056B (en) 2007-05-30
MXPA06004639A (es) 2006-06-27
TWI339586B (en) 2011-04-01
KR20100012105A (ko) 2010-02-05
MA28116A1 (fr) 2006-08-01
US7700128B2 (en) 2010-04-20

Similar Documents

Publication Publication Date Title
CY1117176T1 (el) Στερεο παρασκευασμα το οποιο περιλαμβανει πιογλιταζονη, γλιμεπιριδη και εναν εστερα λιπαρου οξεος πολυοξυαιθυλενο σορβιτανης
CY1111264T1 (el) Στερεο παρασκευασμα που περιλαμβανει αλογλιπτινη και πιογλιταζονη
CY1108700T1 (el) Συνθεσεις απελευθερωσης φαρμακου εστερα αλφα-υδροξυ οξεος και μεθοδοι χρησης
CY1124650T1 (el) Φαρμακευτικο παρασκευασμα που περιεχει ινσουλινη σε κρυσταλλικη μορφη καθως και σε διαλυτοποιημενη μορφη
SV2004001556A (es) Preparaciones acidas de insulina con establidad mejorada
EA200301250A1 (ru) Фармацевтические композиции, содержащие слаборастворимые и/или чувствительные к кислотам лекарственные средства и нейтрализованные кислотные полимеры
CY1106386T1 (el) Υποκατεστημενα παραγωγα 3-πυρρολιδιν-ινδολης
WO2006012527A8 (en) Bivalent linkers and conjugates thereof
BRPI0606112B8 (pt) 3-hetero-aril-3-hidróxi-2-amino-propil aminas e compostos relacionados com atividade analgésica, uso dos mesmos e composição farmacêutica compreendendo os mesmos
CL2009000967A1 (es) Compuesto 4-ciclobutil-n-((2s,5r)-5-hidroxi-2-adamantil)-2-morfolin-4-ilpiridin-5-carboxamida, inhibidor de la enzima 11betahsd1; composicion farmaceutica que lo comprende; y su uso en un procedimiento de tratamiento profilactico o terapeutico de un animal de sangre caliente.
BRPI0413927B8 (pt) composição farmacêutica compreendendo tacrolimus, forma de dosagem, uso da composição, e, método para a preparação da composição
UY29234A1 (es) Derivados de adamantano, composiciones farmacéuticas que los contienen, procedimientos de preparación de ambos y aplicaciones.
CY1111161T1 (el) Χρηση βενζο-συγχωνευμενων ετεροκυκλικων παραγωγων σουλφαμιδιου για τη μειωση των λιπιδιων και τη μειωση των επιπεδων της γλυκοζης στο αιμα
CY1109996T1 (el) Ανοσογονικη συνθεση
EA200400878A1 (ru) Новые эфиры флуоренкарбоновых кислот, способ их получения, а также их применение в качестве лекарственных средств
WO2003061593A3 (en) Novel targeted compositions for diagnostic and therapeutic use
CY1112738T1 (el) Μια συνδυασμενη συνθεση που περιεχει ιβουπροφαινη και παρακεταμολη
GT200400146A (es) Derivados sustituidos del dioxido de tiazol-benzoisotiazol, procedimiento para su preparacion y su uso
CY1108797T1 (el) Α-κρυσταλλικη μορφη του ρανελικου στροντιου, μεθοδος παρασκευης της και φαρμακευτικες συνθεσεις που την περιεχουν
CY1113116T1 (el) Υποκατεστημενες 4-αμινοκυκλοεξανολες
SE0302546D0 (sv) New compounds
ATE493127T1 (de) Verwendung von levo-ornidazol zur herstellung eines antiparasitären infektionswirkstoffs
CY1107230T1 (el) Υποκατεστημενες ενωσεις 1-φαιναιθυλοπιπεριδινης, οι οποιες μεταξυ αλλων χρησιμοποιουνται σαν αναλγητικα
ATE434431T1 (de) Pharmazeutische formulierungen mit kurzketten- sphingolipiden und ihre verwendung
CY1115815T1 (el) Υγρη μορφοποιηση toy g-csf