CY1115948T1 - Θερμικη αποστειρωση γλυκοκορτικοστεροειδων - Google Patents

Θερμικη αποστειρωση γλυκοκορτικοστεροειδων

Info

Publication number
CY1115948T1
CY1115948T1 CY20141101076T CY141101076T CY1115948T1 CY 1115948 T1 CY1115948 T1 CY 1115948T1 CY 20141101076 T CY20141101076 T CY 20141101076T CY 141101076 T CY141101076 T CY 141101076T CY 1115948 T1 CY1115948 T1 CY 1115948T1
Authority
CY
Cyprus
Prior art keywords
glucocorticosteroid
unstable
glucocorticoids
methods
thermal sterilization
Prior art date
Application number
CY20141101076T
Other languages
English (en)
Inventor
Adrian Ashley
Paul Lamb
Donald Mcdonald
John Miller
Martin J Oliver
Mathew Pollard
Original Assignee
Norton Healthcare Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32607464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1115948(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Norton Healthcare Limited filed Critical Norton Healthcare Limited
Publication of CY1115948T1 publication Critical patent/CY1115948T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Dairy Products (AREA)
  • Steroid Compounds (AREA)

Abstract

Η παρούσα εφεύρεση παρέχει μία μέθοδο για την αποστείρωση ενός ασταθούς γλυκοκορτικοστεροειδούς, η οποία μέθοδος περιλαμβάνει θερμική κατεργασία με υγρή θερμότητα του ασταθούς γλυκοκορτικοστεροειδούς στη μορφή ενός αιωρήματος για έναν αποτελεσματικό για αποστείρωση χρόνο. Οι μέθοδοι και οι συνθέσεις σύμφωνα με την εφεύρεση είναι χρήσιμες ως θεραπευτικά εργαλεία για πρόληψη, αντιστροφή, και/ή μείωση των συμπτωμάτων αλλεργικών και/ή φλεγμονωδών παθήσεων σε ένα ασθενές θηλαστικό. Η εφεύρεση παρέχει επίσης μεθόδους και συνθέσεις, οι οποίες μπορεί να χειραγωγηθούν και να υποστούν λεπτή ρύθμιση για να προσαρμοστούν στην(ις) προς αντιμετώπιση πάθηση(εις) προκαλώντας συγχρόνως λιγότερες παρενέργειες.
CY20141101076T 2004-05-17 2014-12-08 Θερμικη αποστειρωση γλυκοκορτικοστεροειδων CY1115948T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0410995.5A GB0410995D0 (en) 2004-05-17 2004-05-17 Heat sterilization of glucocorticosteroids
EP05752889.5A EP1755554B1 (en) 2004-05-17 2005-05-17 Heat sterilization of glucocorticosteroids

Publications (1)

Publication Number Publication Date
CY1115948T1 true CY1115948T1 (el) 2017-01-25

Family

ID=32607464

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20141101076T CY1115948T1 (el) 2004-05-17 2014-12-08 Θερμικη αποστειρωση γλυκοκορτικοστεροειδων

Country Status (21)

Country Link
US (2) US8791096B2 (el)
EP (3) EP1755554B1 (el)
JP (2) JP5116469B2 (el)
KR (1) KR101148446B1 (el)
CN (2) CN1988886B (el)
AU (1) AU2005247422B8 (el)
CA (1) CA2569549C (el)
CY (1) CY1115948T1 (el)
DK (2) DK1755554T3 (el)
ES (2) ES2525877T3 (el)
FI (1) FI2805712T4 (el)
GB (1) GB0410995D0 (el)
HK (2) HK1171971A1 (el)
HU (1) HUE037567T2 (el)
IL (1) IL179066A (el)
LT (1) LT2805712T (el)
MX (1) MXPA06012874A (el)
PL (2) PL2805712T5 (el)
PT (2) PT2805712T (el)
SI (2) SI2805712T1 (el)
WO (1) WO2005115332A2 (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20050941A1 (es) 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
GB0425266D0 (en) * 2004-11-16 2004-12-15 Norton Healthcare Ltd Pharmaceutical manufacturing process
ES2612257T3 (es) * 2011-05-03 2017-05-16 Chiesi Farmaceutici S.P.A. Formulación de suspensión mejorada de dipropionato de beclometasona para administración mediante inhalación
CN104052572B (zh) * 2013-03-11 2019-07-02 北京三星通信技术研究有限公司 一种下行传输方法和用户终端设备
US9867973B2 (en) 2013-06-17 2018-01-16 Medline Industries, Inc. Skin antiseptic applicator and methods of making and using the same
US9511156B2 (en) 2014-01-08 2016-12-06 Carefusion 2200, Inc. Systems, methods, and devices for sterilizing antiseptic solutions
US11027032B2 (en) 2014-01-08 2021-06-08 Carefusion 2200, Inc. Systems, methods, and devices for sterilizing antiseptic solutions
US9895455B2 (en) 2015-06-30 2018-02-20 Carefusion 2200, Inc Systems, methods, and devices for sterilizing antiseptic solutions
CN106310299A (zh) * 2015-06-30 2017-01-11 开尔弗森2200有限公司 用于使防腐剂溶液灭菌的系统、方法和装置
WO2022098321A1 (en) * 2020-11-09 2022-05-12 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Process for the preparation of sterilised suspensions for the administration by inhalation
CN112891328A (zh) * 2021-04-12 2021-06-04 上海方予健康医药科技有限公司 一种吸入用布地奈德混悬液的制备方法

Family Cites Families (18)

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US3692430A (en) 1971-06-18 1972-09-19 John W Timmons Liquid pumping system
US3962430A (en) 1974-08-07 1976-06-08 Merck & Co., Inc. Sterilization of solid non-electrolyte medicinal agents employing sodium chloride
GB9410222D0 (en) * 1994-05-21 1994-07-06 Glaxo Wellcome Australia Ltd Medicaments
US5933781A (en) 1997-01-31 1999-08-03 Qualcomm Incorporated Pilot based, reversed channel power control
SE9704186D0 (sv) * 1997-11-14 1997-11-14 Astra Ab New composition of matter
US6066292A (en) * 1997-12-19 2000-05-23 Bayer Corporation Sterilization process for pharmaceutical suspensions
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EP0938896A1 (en) 1998-01-15 1999-09-01 Novartis AG Autoclavable pharmaceutical compositions containing a chelating agent
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IL155935A0 (en) * 2000-11-24 2003-12-23 Breath Ltd A method of sterilizing a pharmaceutical composition
NL1016981C2 (nl) 2000-12-22 2002-06-25 Nutricia Nv Pasteuriseren of steriliseren.
DE10145361A1 (de) 2001-09-14 2003-04-03 Pari Gmbh Verfahren zur Herstellung von flüssigen, sterilen Zubereitungen zur Inhalation
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EP1574222B1 (en) 2004-03-12 2011-02-09 Cipla Ltd. Sterilization process for steroids

Also Published As

Publication number Publication date
HK1171971A1 (zh) 2013-04-12
SI2805712T1 (en) 2018-07-31
IL179066A (en) 2014-07-31
PT1755554E (pt) 2014-12-11
PT2805712T (pt) 2018-05-24
AU2005247422B8 (en) 2010-12-09
US20140370097A1 (en) 2014-12-18
KR101148446B1 (ko) 2012-05-23
US10314785B2 (en) 2019-06-11
HUE037567T2 (hu) 2018-09-28
US20080139519A1 (en) 2008-06-12
WO2005115332A3 (en) 2006-05-04
JP5116469B2 (ja) 2013-01-09
ES2670706T3 (es) 2018-05-31
FI2805712T4 (fi) 2023-02-09
DK2805712T4 (da) 2022-11-07
CN102600491A (zh) 2012-07-25
SI1755554T1 (sl) 2015-03-31
ES2525877T3 (es) 2014-12-30
AU2005247422A1 (en) 2005-12-08
EP2805712B2 (en) 2022-10-26
CN102600491B (zh) 2015-07-22
GB0410995D0 (en) 2004-06-23
EP1755554A2 (en) 2007-02-28
CN1988886B (zh) 2012-11-07
CA2569549C (en) 2010-09-21
EP3299013A1 (en) 2018-03-28
EP2805712B1 (en) 2018-02-28
IL179066A0 (en) 2007-03-08
EP2805712A1 (en) 2014-11-26
JP2007538089A (ja) 2007-12-27
PL2805712T5 (pl) 2023-02-27
AU2005247422B2 (en) 2010-12-02
EP1755554B1 (en) 2014-11-12
KR20070037436A (ko) 2007-04-04
HK1252557A1 (zh) 2019-05-31
CA2569549A1 (en) 2005-12-08
JP5473029B2 (ja) 2014-04-16
DK1755554T3 (en) 2014-12-15
US8791096B2 (en) 2014-07-29
CN1988886A (zh) 2007-06-27
LT2805712T (lt) 2018-07-10
PL2805712T3 (pl) 2018-08-31
WO2005115332A2 (en) 2005-12-08
JP2013014597A (ja) 2013-01-24
PL1755554T3 (pl) 2015-04-30
MXPA06012874A (es) 2007-02-15
DK2805712T3 (en) 2018-05-22
ES2670706T5 (es) 2023-03-09

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