CY1115374T1 - Αναστολεiς μετ για ενiσχυση αποτελεσματικoτητας ραδιοθεραπειας - Google Patents

Αναστολεiς μετ για ενiσχυση αποτελεσματικoτητας ραδιοθεραπειας

Info

Publication number
CY1115374T1
CY1115374T1 CY20141100561T CY141100561T CY1115374T1 CY 1115374 T1 CY1115374 T1 CY 1115374T1 CY 20141100561 T CY20141100561 T CY 20141100561T CY 141100561 T CY141100561 T CY 141100561T CY 1115374 T1 CY1115374 T1 CY 1115374T1
Authority
CY
Cyprus
Prior art keywords
met
suspension
enhance radiotherapy
cdrs
radiotherapy efficacy
Prior art date
Application number
CY20141100561T
Other languages
Greek (el)
English (en)
Inventor
Paolo Maria Comoglio
Carla Boccaccio
Fiorella Petronzelli
Santis Rita De
Original Assignee
Metheresis Translational Research Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metheresis Translational Research Sa filed Critical Metheresis Translational Research Sa
Publication of CY1115374T1 publication Critical patent/CY1115374T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CY20141100561T 2011-03-18 2014-07-24 Αναστολεiς μετ για ενiσχυση αποτελεσματικoτητας ραδιοθεραπειας CY1115374T1 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11158861.2A EP2500036B1 (en) 2011-03-18 2011-03-18 MET inhibitors for enhancing radiotherapy efficacy

Publications (1)

Publication Number Publication Date
CY1115374T1 true CY1115374T1 (el) 2017-01-04

Family

ID=44260211

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20141100561T CY1115374T1 (el) 2011-03-18 2014-07-24 Αναστολεiς μετ για ενiσχυση αποτελεσματικoτητας ραδιοθεραπειας

Country Status (22)

Country Link
US (1) US20120237524A1 (enExample)
EP (1) EP2500036B1 (enExample)
JP (1) JP5671487B2 (enExample)
KR (1) KR101540838B1 (enExample)
CN (1) CN102688491A (enExample)
AU (1) AU2012201303B2 (enExample)
BR (1) BR102012006063B1 (enExample)
CA (1) CA2769991C (enExample)
CY (1) CY1115374T1 (enExample)
DK (1) DK2500036T3 (enExample)
EA (1) EA028590B1 (enExample)
ES (1) ES2489475T3 (enExample)
HR (1) HRP20140729T1 (enExample)
IL (1) IL218293A (enExample)
MX (1) MX2012003084A (enExample)
PL (1) PL2500036T3 (enExample)
PT (1) PT2500036E (enExample)
RS (1) RS53468B (enExample)
SG (1) SG184637A1 (enExample)
SI (1) SI2500036T1 (enExample)
SM (1) SMT201400106B (enExample)
ZA (1) ZA201201992B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
TWI782930B (zh) 2016-11-16 2022-11-11 美商再生元醫藥公司 抗met抗體,結合met之雙特異性抗原結合分子及其使用方法
IT201800009282A1 (it) * 2018-10-09 2020-04-09 Metis Prec Medicine Sb Srl Nuovo agente terapeutico per il trattamento di un tumore e/o metastasi
CN110320365B (zh) * 2019-07-06 2022-07-22 湖南莱拓福生物科技有限公司 NF-κB RelA/p65蛋白位点特异性磷酸化诊断试剂盒
US11896682B2 (en) 2019-09-16 2024-02-13 Regeneron Pharmaceuticals, Inc. Radiolabeled MET binding proteins for immuno-PET imaging and methods of use thereof
WO2024206858A1 (en) 2023-03-30 2024-10-03 Revolution Medicines, Inc. Compositions for inducing ras gtp hydrolysis and uses thereof
WO2024229406A1 (en) 2023-05-04 2024-11-07 Revolution Medicines, Inc. Combination therapy for a ras related disease or disorder
US20250049810A1 (en) 2023-08-07 2025-02-13 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
TW202530228A (zh) 2023-10-12 2025-08-01 美商銳新醫藥公司 Ras抑制劑
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
WO2025255438A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI310684B (en) * 2000-03-27 2009-06-11 Bristol Myers Squibb Co Synergistic pharmaceutical kits for treating cancer
BRPI0407446A (pt) * 2003-02-13 2006-01-31 Pharmacia Corp Anticorpos para c-met para o tratamento de cânceres
EP1648998B1 (en) * 2003-07-18 2014-10-01 Amgen Inc. Specific binding agents to hepatocyte growth factor
HN2004000285A (es) * 2003-08-04 2006-04-27 Pfizer Prod Inc ANTICUERPOS DIRIGIDOS A c-MET
EP1981981B1 (en) * 2006-02-06 2011-06-29 Metheresis Translational Research SA Anti-met monoclonal antibody, fragments and vectors thereof, for the treatment of tumors and corresponding products
EP2019116A1 (en) * 2007-07-26 2009-01-28 Helmholtz-Zentrum für Infektionsforschung GmbH Inhibitor of the met-receptor and its use

Also Published As

Publication number Publication date
CA2769991C (en) 2018-05-15
RS53468B (sr) 2014-12-31
CA2769991A1 (en) 2012-09-18
AU2012201303B2 (en) 2013-11-07
AU2012201303A1 (en) 2012-10-04
KR20120106582A (ko) 2012-09-26
SG184637A1 (en) 2012-10-30
EA201200329A3 (ru) 2013-01-30
ES2489475T3 (es) 2014-09-02
PT2500036E (pt) 2014-08-25
IL218293A (en) 2016-06-30
HRP20140729T1 (hr) 2014-08-29
JP2012196206A (ja) 2012-10-18
PL2500036T3 (pl) 2014-10-31
EA201200329A2 (ru) 2012-09-28
IL218293A0 (en) 2012-07-31
BR102012006063A2 (pt) 2021-11-16
SMT201400106B (it) 2014-11-10
KR101540838B1 (ko) 2015-08-06
US20120237524A1 (en) 2012-09-20
HK1174539A1 (en) 2013-06-14
JP5671487B2 (ja) 2015-02-18
CN102688491A (zh) 2012-09-26
EP2500036B1 (en) 2014-05-07
MX2012003084A (es) 2012-09-17
DK2500036T3 (da) 2014-08-04
BR102012006063A8 (pt) 2022-11-08
SI2500036T1 (sl) 2014-09-30
EP2500036A1 (en) 2012-09-19
EA028590B1 (ru) 2017-12-29
BR102012006063B1 (pt) 2023-03-07
ZA201201992B (en) 2015-05-27

Similar Documents

Publication Publication Date Title
CY1115374T1 (el) Αναστολεiς μετ για ενiσχυση αποτελεσματικoτητας ραδιοθεραπειας
CY1121148T1 (el) Παραγοντες συνδεσης vegf/dll4 και χρησεις αυτων
CY1122707T1 (el) Ετεροκυκλικοι αναστολεις γλουταμινασης
EA201492137A1 (ru) Антитела к cd33 и их применение в лечении рака
MX2020010639A (es) Anticuerpos humanizados a liv-1 y uso de los mismos para tratar cancer.
HRP20182202T1 (hr) Upotreba t stanica modificiranih himernim receptorom za antigen za liječenje raka
CY1120359T1 (el) Σταθερες φαρμακοτεχνικες μορφες αντισωματων εναντι ανθρωπινου υποδοχεα pd-1 προγραμματισμενου θανατου και σχετικες θεραπειες
PH12016501384A1 (en) Human antibodies to pd-l1
TR201905909T4 (tr) Kanser tedavisi için anti-4-1bb antikorlarının ve adcc indükleyici antikorların kombinasyonları.
CY1119445T1 (el) Αντισωματα εναντι του ανθρωπινου gdf8
MX370818B (es) Anticuerpos anti-b7-h1 para tratar tumores.
EA201690167A1 (ru) Гуманизованные или химерные антитела к cd3
MX2016012094A (es) Composiciones de anticuerpos para tratamiento tumoral.
DK2766040T3 (da) Pertuzumab, trastuzumab, docetaxel og carboplatin til behandling af brystkræft i et tidligt stadie
EA201890162A1 (ru) Антитела к cd40 с повышенной агонистической активностью
MX360141B (es) Anticuerpos contra integrina alfavhbeta6 y uso de los mismos para tratar cancer.
NZ626610A (en) Antibodies that bind csf1r
EA201290727A1 (ru) Пирролбензодиазепины и их конъюгаты
NZ611785A (en) Anti-notch1 antibodies
EA201201474A1 (ru) Способы лечения рака молочной железы
BR112014024017A8 (pt) Métodos de tratamento de um tipo de câncer, de tratamento do carcinoma, para selecionar uma terapia e para quantificação e inibidor de her3
EA201490944A1 (ru) Двойной ингибитор met и vegf для лечения рака
EA201690599A1 (ru) Конъюгированные антитела против ly75 для лечения рака
EA201300610A1 (ru) Хиназолинкарбоксамидазетидины
EA201400339A1 (ru) Новые имидазоламины в качестве модуляторов киназной активности