CY1111115T1 - Μουσκαρινικοι αγωνιστες - Google Patents

Μουσκαρινικοι αγωνιστες

Info

Publication number
CY1111115T1
CY1111115T1 CY20111100057T CY111100057T CY1111115T1 CY 1111115 T1 CY1111115 T1 CY 1111115T1 CY 20111100057 T CY20111100057 T CY 20111100057T CY 111100057 T CY111100057 T CY 111100057T CY 1111115 T1 CY1111115 T1 CY 1111115T1
Authority
CY
Cyprus
Prior art keywords
muscarian
fighters
processes
construction
amide
Prior art date
Application number
CY20111100057T
Other languages
English (en)
Inventor
Julie Kay Bush
Perry Clark Heath
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of CY1111115T1 publication Critical patent/CY1111115T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Η παρούσα εφεύρεση παρέχει κρυσταλλικό ημιένυδρο (R)-(6-(1-((4-φθοροβενζυλο)μεθυλαμινο)αιθυλιδινοαμινο)-2(R)-υδροξυϊνδαν-1-υλο)αμίδιο διφαινυλο-4-καρβοξυλικού οξέος, συνθέσεις του, μεθόδους χρήσης τους, διεργασίες για κατασκευή τους, και διεργασίες για την κατασκευή ενδιάμεσων τους.
CY20111100057T 2002-08-22 2011-01-19 Μουσκαρινικοι αγωνιστες CY1111115T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40544302P 2002-08-22 2002-08-22
EP03792989A EP1534667B1 (en) 2002-08-22 2003-08-12 Muscarinic agonists

Publications (1)

Publication Number Publication Date
CY1111115T1 true CY1111115T1 (el) 2015-06-11

Family

ID=31946873

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100057T CY1111115T1 (el) 2002-08-22 2011-01-19 Μουσκαρινικοι αγωνιστες

Country Status (19)

Country Link
US (1) US7160922B2 (el)
EP (1) EP1534667B1 (el)
JP (1) JP4469280B2 (el)
CN (1) CN100554247C (el)
AR (1) AR040889A1 (el)
AT (1) ATE491683T1 (el)
AU (1) AU2003256791B2 (el)
BR (1) BR0313161A (el)
CA (1) CA2493958C (el)
CY (1) CY1111115T1 (el)
DE (1) DE60335380D1 (el)
DK (1) DK1534667T3 (el)
ES (1) ES2355213T3 (el)
MX (1) MXPA05002080A (el)
PE (1) PE20040894A1 (el)
PT (1) PT1534667E (el)
SI (1) SI1534667T1 (el)
TW (1) TW200410922A (el)
WO (1) WO2004018411A1 (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7678363B2 (en) * 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP2552889A1 (en) 2010-03-29 2013-02-06 Basf Se Fungicidal iminoderivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1556788A (zh) * 2001-09-21 2004-12-22 毒蕈碱受体激动剂

Also Published As

Publication number Publication date
SI1534667T1 (sl) 2011-02-28
CN1675173A (zh) 2005-09-28
WO2004018411A1 (en) 2004-03-04
ES2355213T3 (es) 2011-03-23
JP2005536549A (ja) 2005-12-02
TW200410922A (en) 2004-07-01
AU2003256791A1 (en) 2004-03-11
BR0313161A (pt) 2005-06-14
MXPA05002080A (es) 2005-08-18
AR040889A1 (es) 2005-04-20
JP4469280B2 (ja) 2010-05-26
ATE491683T1 (de) 2011-01-15
CA2493958A1 (en) 2004-03-04
PE20040894A1 (es) 2004-11-25
DK1534667T3 (da) 2011-02-14
US20060122280A1 (en) 2006-06-08
PT1534667E (pt) 2011-01-19
US7160922B2 (en) 2007-01-09
CA2493958C (en) 2010-11-09
AU2003256791B2 (en) 2008-12-11
DE60335380D1 (de) 2011-01-27
EP1534667A1 (en) 2005-06-01
CN100554247C (zh) 2009-10-28
EP1534667B1 (en) 2010-12-15

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