CY1109773T1 - Φαρμακα για ασθενειες των αρθρωσεων - Google Patents
Φαρμακα για ασθενειες των αρθρωσεωνInfo
- Publication number
- CY1109773T1 CY1109773T1 CY20101100507T CY101100507T CY1109773T1 CY 1109773 T1 CY1109773 T1 CY 1109773T1 CY 20101100507 T CY20101100507 T CY 20101100507T CY 101100507 T CY101100507 T CY 101100507T CY 1109773 T1 CY1109773 T1 CY 1109773T1
- Authority
- CY
- Cyprus
- Prior art keywords
- diseases
- zinc
- medications
- joints
- hyaluronic acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Φάρμακα για ασθένειες των αρθρώσεων όπως η ρευματοειδής αρθρίτιδα τα οποία περιέχουν ως ενεργό συστατικό ένα σύμπλοκο (συνδυασμός) υαλουρονικού οξέος με ψευδάργυρο. Σε σύγκριση με το υαλουρονικό οξύ και τον ψευδάργυρο (δηλαδή τα συστατικά αυτού), το σύμπλοκο αυτό αναστέλλει συνεργιστικά τον πολλαπλασιασμό των αρθρικών κυττάρων και συνεπώς ρυθμίζει την παραγωγή του ιστοκλαστικού ενζύμου ΜΜΡ-9 που παράγεται από αρθρικά κύτταρα.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP06371899A JP2003089647A (ja) | 1999-03-10 | 1999-03-10 | 関節性疾患治療剤 |
EP00908017A EP1166788B8 (en) | 1999-03-10 | 2000-03-10 | Remedies for joint diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1109773T1 true CY1109773T1 (el) | 2014-09-10 |
Family
ID=13237463
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20101100507T CY1109773T1 (el) | 1999-03-10 | 2010-06-08 | Φαρμακα για ασθενειες των αρθρωσεων |
Country Status (21)
Country | Link |
---|---|
US (1) | US6608043B1 (el) |
EP (1) | EP1166788B8 (el) |
JP (1) | JP2003089647A (el) |
KR (1) | KR100728096B1 (el) |
CN (1) | CN1165315C (el) |
AT (1) | ATE466584T1 (el) |
AU (1) | AU2942500A (el) |
BG (1) | BG65681B1 (el) |
CA (1) | CA2364451C (el) |
CY (1) | CY1109773T1 (el) |
CZ (1) | CZ301736B6 (el) |
DE (1) | DE60044341D1 (el) |
DK (1) | DK1166788T3 (el) |
EA (1) | EA005010B1 (el) |
EE (1) | EE04660B1 (el) |
ES (1) | ES2344677T3 (el) |
PL (1) | PL200848B1 (el) |
PT (1) | PT1166788E (el) |
SK (1) | SK287223B6 (el) |
UA (1) | UA72913C2 (el) |
WO (1) | WO2000053194A1 (el) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0303779A2 (en) * | 2003-11-20 | 2006-02-28 | Richter Gedeon Vegyeszet | Pharmaceutical compositions containing hyaluronan complex for the treatment of sclerosis multiplex |
ITRM20030590A1 (it) * | 2003-12-22 | 2005-06-23 | Univ Siena | Formulazione a base di polimetafosfati per la cura di artropatie microcristalline. |
WO2005089800A1 (ja) * | 2004-03-17 | 2005-09-29 | Locomogene, Inc. | hsHRD3を含む医薬組成物 |
US20070099867A1 (en) * | 2005-05-24 | 2007-05-03 | Glycoscience Laboratories, Inc. | Pharmaceutical agent containing hyaluronan as an active ingredient |
CA2560844C (en) * | 2005-09-26 | 2011-05-17 | Glycoscience Laboratories, Inc. | Pharmaceutical agent containing hyaluronan as an active ingredient |
JP2009091248A (ja) * | 2006-01-17 | 2009-04-30 | Toshitsu Kagaku Kenkyusho:Kk | 外傷性神経障害および/または運動機能障害の治療薬 |
BRPI0621470A2 (pt) | 2006-12-05 | 2011-12-13 | Glycoscience Lab Inc | agente terapêutico para artrite degenerativa |
FR2927255B1 (fr) * | 2008-02-07 | 2011-08-12 | Keysan Consulting | Produits injectables biocompatibles a liberation de zinc et/ou de sel de saccharide sous forme de zinc et leurs utilisations. |
US8462765B2 (en) * | 2008-08-20 | 2013-06-11 | Qualcomm Incorporated | Method and apparatus to perform ranging operations for wireless stations |
JP5587637B2 (ja) * | 2009-04-10 | 2014-09-10 | 生化学工業株式会社 | マトリックスメタロプロテアーゼ阻害剤及びその用途 |
HUP0900717A3 (en) | 2009-11-18 | 2012-02-28 | Richter Gedeon Nyrt | Pharmaceutical composition for urological use containing zinc hyaluronate |
US8398611B2 (en) | 2010-12-28 | 2013-03-19 | Depuy Mitek, Inc. | Compositions and methods for treating joints |
US8524662B2 (en) | 2010-12-28 | 2013-09-03 | Depuy Mitek, Llc | Compositions and methods for treating joints |
US8455436B2 (en) | 2010-12-28 | 2013-06-04 | Depuy Mitek, Llc | Compositions and methods for treating joints |
US8623839B2 (en) | 2011-06-30 | 2014-01-07 | Depuy Mitek, Llc | Compositions and methods for stabilized polysaccharide formulations |
ES2665254T3 (es) * | 2011-07-12 | 2018-04-25 | Holy Stone Healthcare Co., Ltd. | Composiciones que comprenden ácido hialurónico para tratamiento y prevención de enfermedades relacionadas con las mucosas |
US9682099B2 (en) | 2015-01-20 | 2017-06-20 | DePuy Synthes Products, Inc. | Compositions and methods for treating joints |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4746504A (en) * | 1986-03-14 | 1988-05-24 | Bio-Technology General Corp. | Heavy metal salts of hyaluronic acid and their use as antimicrobial agents |
CA1291123C (en) | 1986-03-14 | 1991-10-22 | Abraham Nimrod | Heavy metal salts of hyaluronic acid useful as antimicrobial agents |
CA1327354C (en) * | 1987-03-19 | 1994-03-01 | David Cullis-Hill | Anti-inflamatory compounds and compositions |
AU616502B2 (en) * | 1988-04-22 | 1991-10-31 | Medvet Science Pty. Ltd. | Treatment of inflammatory disorders in humans |
HU203372B (en) | 1989-02-24 | 1991-07-29 | Richter Gedeon Vegyeszet | Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient |
CZ202591A3 (cs) * | 1991-07-02 | 1993-01-13 | Hypro Vyzkum | Prostředek pro prevenci dekubitft a topickou terapii kožních lézt |
US5744442A (en) * | 1992-08-26 | 1998-04-28 | Bristol Meyers Squibb Company | Regulation of cellular invasiveness |
IT1281877B1 (it) * | 1995-05-10 | 1998-03-03 | Fidia Advanced Biopolymers Srl | Sali di metalli pesanti di succinil derivati dell'acido ialuronico e loro impiego come potenziali agenti terapeutici |
IT1288290B1 (it) | 1996-06-21 | 1998-09-11 | Fidia Spa In Amministrazione S | Acido ialuronico autoreticolato e relative composizioni farmaceutiche per il trattamento delle artropatie |
EP0834319A1 (en) * | 1996-10-07 | 1998-04-08 | Kartar Dr. Lalvani | Mineral and vitamin combinations in arthritic pain |
-
1999
- 1999-03-10 JP JP06371899A patent/JP2003089647A/ja active Pending
-
2000
- 2000-03-10 EE EEP200100478A patent/EE04660B1/xx unknown
- 2000-03-10 DE DE60044341T patent/DE60044341D1/de not_active Expired - Lifetime
- 2000-03-10 WO PCT/JP2000/001487 patent/WO2000053194A1/ja not_active Application Discontinuation
- 2000-03-10 ES ES00908017T patent/ES2344677T3/es not_active Expired - Lifetime
- 2000-03-10 DK DK00908017.7T patent/DK1166788T3/da active
- 2000-03-10 CZ CZ20013110A patent/CZ301736B6/cs not_active IP Right Cessation
- 2000-03-10 AU AU29425/00A patent/AU2942500A/en not_active Abandoned
- 2000-03-10 CN CNB008047391A patent/CN1165315C/zh not_active Expired - Lifetime
- 2000-03-10 CA CA2364451A patent/CA2364451C/en not_active Expired - Lifetime
- 2000-03-10 PL PL350289A patent/PL200848B1/pl unknown
- 2000-03-10 AT AT00908017T patent/ATE466584T1/de active
- 2000-03-10 EA EA200100963A patent/EA005010B1/ru not_active IP Right Cessation
- 2000-03-10 EP EP00908017A patent/EP1166788B8/en not_active Expired - Lifetime
- 2000-03-10 PT PT00908017T patent/PT1166788E/pt unknown
- 2000-03-10 US US09/936,245 patent/US6608043B1/en not_active Expired - Lifetime
- 2000-03-10 KR KR1020017011505A patent/KR100728096B1/ko active IP Right Grant
- 2000-03-10 SK SK1250-2001A patent/SK287223B6/sk not_active IP Right Cessation
- 2000-10-03 UA UA2001096233A patent/UA72913C2/uk unknown
-
2001
- 2001-09-10 BG BG105885A patent/BG65681B1/bg unknown
-
2010
- 2010-06-08 CY CY20101100507T patent/CY1109773T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
PL200848B1 (pl) | 2009-02-27 |
SK12502001A3 (sk) | 2002-02-05 |
EP1166788B8 (en) | 2010-06-16 |
CA2364451A1 (en) | 2000-09-14 |
UA72913C2 (en) | 2005-05-16 |
DK1166788T3 (da) | 2010-08-23 |
SK287223B6 (sk) | 2010-03-08 |
WO2000053194A1 (fr) | 2000-09-14 |
DE60044341D1 (de) | 2010-06-17 |
PL350289A1 (en) | 2002-12-02 |
EE200100478A (et) | 2003-02-17 |
EP1166788A4 (en) | 2007-10-10 |
ES2344677T3 (es) | 2010-09-03 |
CN1343122A (zh) | 2002-04-03 |
BG105885A (en) | 2002-06-28 |
KR20010108343A (ko) | 2001-12-07 |
EA200100963A1 (ru) | 2002-02-28 |
BG65681B1 (bg) | 2009-06-30 |
EP1166788B1 (en) | 2010-05-05 |
PT1166788E (pt) | 2010-06-25 |
EP1166788A1 (en) | 2002-01-02 |
CA2364451C (en) | 2011-08-02 |
CZ20013110A3 (cs) | 2002-01-16 |
CN1165315C (zh) | 2004-09-08 |
CZ301736B6 (cs) | 2010-06-09 |
KR100728096B1 (ko) | 2007-06-14 |
ATE466584T1 (de) | 2010-05-15 |
EE04660B1 (et) | 2006-08-15 |
AU2942500A (en) | 2000-09-28 |
JP2003089647A (ja) | 2003-03-28 |
EA005010B1 (ru) | 2004-10-28 |
US6608043B1 (en) | 2003-08-19 |
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