CY1109579T1 - Μιμητοσωματα του πυρηνα αρθρωσης μιμητικα της ανθρωπινης ερο, συνθεσεις, μεθοδοι και χρησεις - Google Patents

Μιμητοσωματα του πυρηνα αρθρωσης μιμητικα της ανθρωπινης ερο, συνθεσεις, μεθοδοι και χρησεις

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Publication number
CY1109579T1
CY1109579T1 CY20091101155T CY091101155T CY1109579T1 CY 1109579 T1 CY1109579 T1 CY 1109579T1 CY 20091101155 T CY20091101155 T CY 20091101155T CY 091101155 T CY091101155 T CY 091101155T CY 1109579 T1 CY1109579 T1 CY 1109579T1
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Cyprus
Prior art keywords
knowledge
methods
compositions
mimetics
keywords
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CY20091101155T
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English (en)
Inventor
George Heavner
David M Knight
Bernard Scallon
John Ghrayeb
Thomas C Nesspor
Chichi Huang
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Centocor Ortho Biotech, Inc.
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Application filed by Centocor Ortho Biotech, Inc. filed Critical Centocor Ortho Biotech, Inc.
Publication of CY1109579T1 publication Critical patent/CY1109579T1/el

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/505Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/53Hinge
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71Decreased effector function due to an Fc-modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
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  • Peptides Or Proteins (AREA)

Abstract

Η παρούσα εφεύρεση αφορά τουλάχιστον ένα νέο μιμητικό ανθρώπινης ΕΡΟ πυρήνα άρθρωσης μιμητόσωμα ή ένα προδιαγραφέν τμήμα ή παραλλαγή που συμπεριλαμβάνει απομονωθέντα νουκλεϊνικά οξέα που κωδικοποιούν τουλάχιστον ένα μιμητικό ΕΡΟ πυρήνα άρθρωσης μιμητόσωμα ή προδιαγραφέν τμήμα ή παραλλαγή, ΕΡΟ μιμητικό πυρήνα άρθρωσης μιμητόσωμα ή προδιαγραφέν τμήμα ή παραλλαγές, φορείς, κύτταρα ξενιστές, διαγονιδιακά ζώα ή φυτά και μεθόδους κατασκευής και χρήσης αυτών που συμπεριλαμβάνουν θεραπευτικές συνθέσεις, μεθόδους και συσκευές.
CY20091101155T 2003-09-30 2009-11-06 Μιμητοσωματα του πυρηνα αρθρωσης μιμητικα της ανθρωπινης ερο, συνθεσεις, μεθοδοι και χρησεις CY1109579T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50734903P 2003-09-30 2003-09-30
EP04783275A EP1675579B1 (en) 2003-09-30 2004-09-03 Human epo mimetic hinge core mimetibodies, compositions, methods and uses

Publications (1)

Publication Number Publication Date
CY1109579T1 true CY1109579T1 (el) 2014-08-13

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CY20091101155T CY1109579T1 (el) 2003-09-30 2009-11-06 Μιμητοσωματα του πυρηνα αρθρωσης μιμητικα της ανθρωπινης ερο, συνθεσεις, μεθοδοι και χρησεις

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EP (2) EP1675579B1 (el)
JP (1) JP4810428B2 (el)
KR (1) KR101201339B1 (el)
CN (1) CN1894275B (el)
AR (1) AR046415A1 (el)
AT (1) ATE439370T1 (el)
AU (1) AU2004277884B2 (el)
BR (1) BRPI0414893A (el)
CA (1) CA2540665A1 (el)
CO (1) CO5690612A2 (el)
CR (1) CR8320A (el)
CY (1) CY1109579T1 (el)
DE (1) DE602004022571D1 (el)
DK (1) DK1675579T3 (el)
EA (1) EA009377B1 (el)
EC (1) ECSP066466A (el)
ES (1) ES2329799T3 (el)
HK (1) HK1091413A1 (el)
IL (2) IL174676A (el)
NO (1) NO20061931L (el)
NZ (1) NZ546287A (el)
PL (1) PL1675579T3 (el)
PT (1) PT1675579E (el)
SG (1) SG149074A1 (el)
SI (1) SI1675579T1 (el)
TW (1) TWI344987B (el)
UA (1) UA89481C2 (el)
WO (1) WO2005032460A2 (el)
ZA (1) ZA200603425B (el)

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