CY1109450T1 - Μεθοδοι παρασκευης πεπτιδιων - Google Patents

Μεθοδοι παρασκευης πεπτιδιων

Info

Publication number
CY1109450T1
CY1109450T1 CY20091100495T CY091100495T CY1109450T1 CY 1109450 T1 CY1109450 T1 CY 1109450T1 CY 20091100495 T CY20091100495 T CY 20091100495T CY 091100495 T CY091100495 T CY 091100495T CY 1109450 T1 CY1109450 T1 CY 1109450T1
Authority
CY
Cyprus
Prior art keywords
peptide
cationic
amino acids
methods
sectors
Prior art date
Application number
CY20091100495T
Other languages
English (en)
Inventor
Oeystein Rekdal
John Sigurd Svendsen
Mari Wikman
Terese Solstad
Nannan Yang
Original Assignee
Lytix Biopharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lytix Biopharma As filed Critical Lytix Biopharma As
Publication of CY1109450T1 publication Critical patent/CY1109450T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Semiconductor Lasers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε μια μέθοδο παραγωγής ενός βιοενεργού πεπτιδίου, όπου το εν λόγω πεπτίδιο είναι 7 έως 25 αμινοξέα σε μήκος, έχει τουλάχιστον 3 κατιονικά αμινοξέα και είναι ικανό να σχηματίσει μία αμφιπαθή α-έλικα, η οποία μέθοδος περιλαμβάνει την ταυτοποίηση ενός κατιονικού τομέα και το διαχωρισμό του εναπομείναντος τμήματος του πεπτιδίου σε τρεις επιπλέον τομείς οι οποίοι είναι ουσιαστικά ίσοι σε μέγεθος, και την ενσωμάτωση τουλάχιστον του 60% του όγκου και του λιπόφιλου που παρέχεται από τις ομάδες R των αμινοξέων σε τομείς που πλαισιώνουν τον κατιονικό τομέα· και στις χρήσεις των πεπτιδίων που παράγονται κατ' αυτόν τον τρόπο στη θεραπεία, συγκεκριμένα στην αγωγή των καλοηθών ή κακοηθών όγκων.
CY20091100495T 2000-03-09 2009-05-08 Μεθοδοι παρασκευης πεπτιδιων CY1109450T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0005702.6A GB0005702D0 (en) 2000-03-09 2000-03-09 Method
EP00956720A EP1259536B1 (en) 1999-08-31 2000-08-31 Methods of peptide preparation

Publications (1)

Publication Number Publication Date
CY1109450T1 true CY1109450T1 (el) 2014-08-13

Family

ID=9887296

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100495T CY1109450T1 (el) 2000-03-09 2009-05-08 Μεθοδοι παρασκευης πεπτιδιων

Country Status (14)

Country Link
US (1) US7393824B1 (el)
EP (1) EP1259536B1 (el)
JP (1) JP4902919B2 (el)
AT (1) ATE422502T1 (el)
AU (1) AU781243B2 (el)
CA (1) CA2382544A1 (el)
CY (1) CY1109450T1 (el)
DE (1) DE60041556D1 (el)
DK (1) DK1259536T3 (el)
ES (1) ES2322228T3 (el)
GB (1) GB0005702D0 (el)
NO (1) NO330170B1 (el)
PT (1) PT1259536E (el)
WO (1) WO2001019852A2 (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8680059B2 (en) 1998-05-20 2014-03-25 Biotempt B.V. Oligopeptide acetate and formulations thereof
US20030220258A1 (en) 2001-12-21 2003-11-27 Robbert Benner Treatment of ischemic events
US8283315B2 (en) 1998-08-28 2012-10-09 Lytix Biopharma As Inhibition of tumour growth
GB0005703D0 (en) * 2000-03-09 2000-05-03 Alpharma As Compounds
NO20031818D0 (no) * 2003-04-23 2003-04-23 Uni I Tromsoe Fremgangsmåte av bioaktiv peptid forberedelse
WO2007004869A2 (en) * 2005-07-05 2007-01-11 Biotempt B.V. Treatment of tumors
EP1864692A1 (en) 2006-06-07 2007-12-12 Biotempt B.V. Use of peptides for the control of radiation injury
CN102089320B (zh) 2008-01-24 2015-11-25 埃斯佩兰斯医药公司 溶解结构域融合构建体及其制备和使用方法
GB0821616D0 (en) 2008-11-26 2008-12-31 Lytix Biopharma As Compounds
WO2013124436A1 (en) * 2012-02-23 2013-08-29 University Of East London Synthetic anti-microbial peptides with a minority of cationic and a majority hydrophobic side chains
KR20210090298A (ko) 2012-10-30 2021-07-19 에스퍼란스 파마슈티컬스, 인코포레이티드 항체/약물 컨쥬게이트 및 이의 사용 방법
GB201401877D0 (en) 2014-02-04 2014-03-19 Univ Tromsoe Peptides
CA2972397A1 (en) * 2014-10-08 2016-04-14 Nrl Pharma, Inc. Inhibitor of extracellular trap formation in leukocyte
GB201810635D0 (en) * 2018-06-28 2018-08-15 Norut Northern Res Institute As Peptides and cancer treatment
CN111704652B (zh) * 2020-06-02 2022-04-22 昆明医科大学 一种抗光损伤皮肤保护活性多肽om-gl15及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5547939A (en) * 1991-06-14 1996-08-20 The Regents Of The University Of California Broad spectrum antimicrobial compounds and methods of use
AU5386996A (en) 1995-04-05 1996-10-23 Picower Institute For Medical Research, The Agents for binding to advanced glycosylation endproducts, an d methods of their use
AU3872797A (en) * 1996-08-12 1998-03-06 A+ Science Invest Ab Treatment and prevention of infections, inflammations and/or tumours with lactoferrin and/or lactoferricin
US6333311B1 (en) * 1997-02-03 2001-12-25 Pharming Useful properties of human lactoferrin and variants thereof
GB9818938D0 (en) * 1998-08-28 1998-10-21 Alpharma As Bioactive peptides

Also Published As

Publication number Publication date
AU6858700A (en) 2001-04-17
JP4902919B2 (ja) 2012-03-21
WO2001019852A8 (en) 2004-04-15
EP1259536B1 (en) 2009-02-11
DK1259536T3 (da) 2009-06-08
NO20020950D0 (no) 2002-02-27
NO20020950L (no) 2002-04-25
EP1259536A2 (en) 2002-11-27
ATE422502T1 (de) 2009-02-15
WO2001019852A2 (en) 2001-03-22
DE60041556D1 (de) 2009-03-26
ES2322228T3 (es) 2009-06-18
NO330170B1 (no) 2011-02-28
AU781243B2 (en) 2005-05-12
GB0005702D0 (en) 2000-05-03
PT1259536E (pt) 2009-05-14
JP2003516931A (ja) 2003-05-20
CA2382544A1 (en) 2001-03-22
US7393824B1 (en) 2008-07-01
WO2001019852A3 (en) 2002-09-12

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