CY1109131T1 - Φαρμακοτεχνικη μορφη βραδειας αποδεσμευσης για pralnacasan - Google Patents

Φαρμακοτεχνικη μορφη βραδειας αποδεσμευσης για pralnacasan

Info

Publication number
CY1109131T1
CY1109131T1 CY20091100457T CY091100457T CY1109131T1 CY 1109131 T1 CY1109131 T1 CY 1109131T1 CY 20091100457 T CY20091100457 T CY 20091100457T CY 091100457 T CY091100457 T CY 091100457T CY 1109131 T1 CY1109131 T1 CY 1109131T1
Authority
CY
Cyprus
Prior art keywords
pralnacasan
pharmaceutical form
evening
release
type
Prior art date
Application number
CY20091100457T
Other languages
English (en)
Inventor
Caren Soennichsen
Roland Wesch
Heiko Meier
Original Assignee
Sanofi-Aventis Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis Deutschland Gmbh filed Critical Sanofi-Aventis Deutschland Gmbh
Publication of CY1109131T1 publication Critical patent/CY1109131T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Δισκίο βραδείας αποδέσμευσης αποτελούμενο από τουλάχιστον δύο στρώσεις, το οποίο χαρακτηρίζεται από το γεγονός ότι τουλάχιστον μία στρώση απελευθερώνει αμέσως το φάρμακο 1S, 9S (RS, 3S) Ν-(2-αιθοξυ -5-οξο -τετραφουρανο -3-υλο) -6,10-διοξο -9-(ισοκινολινο -1-οϋλ -αμινο) -1,2,3,4,7,8,9,10 -οκταϋδρο -6Η-πυριδαζινο [1,2-a] [1,2] διαζεπινο -1-καρβοξαμίδιο και /ή τα άλατα του ή τα παράγωγα του και /ή τα ελεύθερα οξέα εξ' αυτών και ότι τουλάχιστον μία στρώση απελευθερώνει με καθυστέρηση το φάρμακο IS, 9S (RS, 3S) Ν-(2-αιθοξυ -5-οξο -τετραφουρανο -3-υλο) -6,10-διοξο -9-(ισοκινολινο -1-οϋλ -αμινο) -1,2,3,4,7,8,9,10 -οκταϋδρο -6Η-πυριδαζινο [1,2-a] [1,2] διαζεπινο -1-καρβοξαμίδιο και /ή και τα άλατα του ή τα παράγωγα του και /ή τα ελεύθερα οξέα εξ' αυτών για την θεραπεία αυτοάνοσων παθήσεων, διαβήτη τύπου I και τύπου II, ρευματοειδούς αρθρίτιδος, οστεοαρθρίτιδος και /ή ψωριάσεως.
CY20091100457T 2005-10-08 2009-04-23 Φαρμακοτεχνικη μορφη βραδειας αποδεσμευσης για pralnacasan CY1109131T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005048293A DE102005048293A1 (de) 2005-10-08 2005-10-08 Retardformulierung für Pralnacasan
EP06805947A EP1937221B1 (de) 2005-10-08 2006-09-29 Retardformulierung für pralnacasan

Publications (1)

Publication Number Publication Date
CY1109131T1 true CY1109131T1 (el) 2014-07-02

Family

ID=37764039

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100457T CY1109131T1 (el) 2005-10-08 2009-04-23 Φαρμακοτεχνικη μορφη βραδειας αποδεσμευσης για pralnacasan

Country Status (28)

Country Link
US (1) US8231904B2 (el)
EP (1) EP1937221B1 (el)
JP (1) JP2009511441A (el)
KR (1) KR101362679B1 (el)
CN (1) CN101277683B (el)
AT (1) ATE422354T1 (el)
AU (1) AU2006301573B2 (el)
BR (1) BRPI0617184A2 (el)
CA (1) CA2624838C (el)
CY (1) CY1109131T1 (el)
DE (2) DE102005048293A1 (el)
DK (1) DK1937221T3 (el)
ES (1) ES2322202T3 (el)
HK (1) HK1124531A1 (el)
HR (1) HRP20090254T1 (el)
IL (1) IL190511A (el)
MA (1) MA29803B1 (el)
ME (1) ME01735B (el)
MY (1) MY146552A (el)
NO (1) NO339360B1 (el)
NZ (1) NZ567268A (el)
PL (1) PL1937221T3 (el)
PT (1) PT1937221E (el)
RS (1) RS50777B (el)
RU (1) RU2419419C2 (el)
SI (1) SI1937221T1 (el)
WO (1) WO2007042160A1 (el)
ZA (1) ZA200802031B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX342120B (es) * 2010-07-09 2016-09-14 William Owen Wilkison Combinación de sistema de liberación prolongada/inmediata para productos farmacéuticos de vida media corta como el remogliflozin.
WO2012020097A2 (en) * 2010-08-13 2012-02-16 Euro-Celtique S.A. Use of binders for manufacturing storage stable formulations

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204261B1 (en) * 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US5085865A (en) 1989-04-12 1992-02-04 Warner-Lambert Company Sustained release pharmaceutical preparations containing an analgesic and a decongestant
IT1264696B1 (it) * 1993-07-09 1996-10-04 Applied Pharma Res Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata
FR2772615B1 (fr) * 1997-12-23 2002-06-14 Lipha Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
UA81224C2 (uk) * 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
CN1524526A (zh) * 2003-03-02 2004-09-01 颖 王 尼群地平双层缓释制剂
US20050013863A1 (en) * 2003-07-18 2005-01-20 Depomed, Inc., A Corporation Of The State Of California Dual drug dosage forms with improved separation of drugs
CN1579401A (zh) * 2003-08-11 2005-02-16 李亦武 一种止咳平喘药物新剂型及制备方法
US7611728B2 (en) * 2003-09-05 2009-11-03 Supernus Pharmaceuticals, Inc. Osmotic delivery of therapeutic compounds by solubility enhancement
WO2005048979A2 (en) * 2003-10-06 2005-06-02 Torrent Pharmaceuticals Limited Pharmaceutical composition having casing with multiple micro tablets
WO2005051350A2 (en) * 2003-10-28 2005-06-09 Torrent Pharmaceuticals Limited Water dispersible tablet

Also Published As

Publication number Publication date
KR101362679B1 (ko) 2014-02-13
WO2007042160A1 (de) 2007-04-19
CN101277683B (zh) 2013-03-20
EP1937221B1 (de) 2009-02-11
US8231904B2 (en) 2012-07-31
HRP20090254T1 (en) 2009-06-30
NO339360B1 (no) 2016-12-05
RU2419419C2 (ru) 2011-05-27
AU2006301573B2 (en) 2013-01-10
PL1937221T3 (pl) 2009-06-30
CN101277683A (zh) 2008-10-01
ATE422354T1 (de) 2009-02-15
IL190511A (en) 2011-05-31
AU2006301573A1 (en) 2007-04-19
NZ567268A (en) 2010-08-27
KR20080054394A (ko) 2008-06-17
BRPI0617184A2 (pt) 2011-07-12
CA2624838A1 (en) 2007-04-19
RU2008113381A (ru) 2009-10-20
MY146552A (en) 2012-08-30
CA2624838C (en) 2013-11-19
ZA200802031B (en) 2009-08-26
MA29803B1 (fr) 2008-09-01
JP2009511441A (ja) 2009-03-19
NO20081896L (no) 2008-04-21
EP1937221A1 (de) 2008-07-02
ES2322202T3 (es) 2009-06-17
RS50777B (sr) 2010-08-31
US20080279934A1 (en) 2008-11-13
DE502006002851D1 (de) 2009-03-26
ME01735B (me) 2010-08-31
DE102005048293A1 (de) 2007-04-12
SI1937221T1 (sl) 2009-06-30
DK1937221T3 (da) 2009-06-15
HK1124531A1 (en) 2009-07-17
IL190511A0 (en) 2008-11-03
PT1937221E (pt) 2009-04-17

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