CY1105450T1 - Ανυδρο τοπικο δepματικο παρασκευασμα πepιεχον κετοκοναζολη - Google Patents

Ανυδρο τοπικο δepματικο παρασκευασμα πepιεχον κετοκοναζολη

Info

Publication number
CY1105450T1
CY1105450T1 CY20061100516T CY061100516T CY1105450T1 CY 1105450 T1 CY1105450 T1 CY 1105450T1 CY 20061100516 T CY20061100516 T CY 20061100516T CY 061100516 T CY061100516 T CY 061100516T CY 1105450 T1 CY1105450 T1 CY 1105450T1
Authority
CY
Cyprus
Prior art keywords
combination
group
solvent selected
depmatic
ketoconazole
Prior art date
Application number
CY20061100516T
Other languages
English (en)
Inventor
Katharine M. Burnett
Ellen S. Kurtz
Original Assignee
Johnson & Johnson Consumer Companies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson Consumer Companies, Inc. filed Critical Johnson & Johnson Consumer Companies, Inc.
Publication of CY1105450T1 publication Critical patent/CY1105450T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Abstract

Η παρούσα εφεύρεση παρέχει άνυδρες συνθέσεις για την τοπική απόδοση ενός φαρμάκου που περιέχει (Α) ένα ενισχυτικό της διείσδυσης / διαλύτη επιλεγμένο από την ομάδα που περιλαμβάνει αλκοόλη, προπυλενογλυκόλη, ή ένα συνδυασμό αυτών· (Β) μια υγραντική ουσία / διαλύτη επιλεγμένη από την ομάδα που περιλαμβάνει πολυαιθυλενογλυκόλη, γλυκερίνη, σορβιτόλη, ξυλιτόλη, ή οποιονδήποτε συνδυασμό από οποιαδήποτε από τα προηγούμενα· και (C) έναν άνυδρο φορέα. Σε μια εναλλακτική ενσωμάτωση, η παρούσα εφεύρεση παρέχει άνυδρες συνθέσεις για την τοπική απόδοση ενός φαρμάκου το οποίο περιέχει (Α) ένα ενισχυτικό της διείσδυσης / διαλύτη επιλεγμένο από την ομάδα που περιλαμβάνει αλκοόλη, προπυλενογλυκόλη, ή ένα συνδυασμό αυτών· (Β) μια υγραντική ουσία / διαλύτη επιλεγμένη από την ομάδα που περιλαμβάνει πολυαιθυλενογλυκόλη, γλυκερίνη, σορβιτόλη, ξυλιτόλη ή οποιονδήποτε συνδυασμό από οποιαδήποτε από τα προηγούμενα· (C) έναν άνυδρο φορέα· και (D) ένα φάρμακο. Επίσης παρέχονται μέθοδοι για την τοπική απόδοση ενός φαρμάκου σε ένα ζώο, όπως ένα θηλαστικό ή ένας ασθενής άνθρωπος, που χρήζει του φαρμάκου διά της τοπικής χορήγησης στο ζώο των συνθέσεων της παρούσας εφεύρεσης.
CY20061100516T 1998-12-04 2006-04-13 Ανυδρο τοπικο δepματικο παρασκευασμα πepιεχον κετοκοναζολη CY1105450T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/205,474 US6238683B1 (en) 1998-12-04 1998-12-04 Anhydrous topical skin preparations
PCT/US1999/028661 WO2000033877A1 (en) 1998-12-04 1999-12-03 Anhydrous topical skin preparations

Publications (1)

Publication Number Publication Date
CY1105450T1 true CY1105450T1 (el) 2010-04-28

Family

ID=22762331

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061100516T CY1105450T1 (el) 1998-12-04 2006-04-13 Ανυδρο τοπικο δepματικο παρασκευασμα πepιεχον κετοκοναζολη

Country Status (18)

Country Link
US (1) US6238683B1 (el)
EP (2) EP1051193B1 (el)
JP (1) JP4610741B2 (el)
KR (1) KR100619228B1 (el)
CN (2) CN1204923C (el)
AR (1) AR021539A1 (el)
AT (1) ATE318148T1 (el)
AU (2) AU778524B2 (el)
BR (1) BR9907666A (el)
CA (1) CA2319515C (el)
CY (1) CY1105450T1 (el)
DE (1) DE69930004T2 (el)
DK (1) DK1051193T3 (el)
ES (1) ES2258347T3 (el)
HK (1) HK1031342A1 (el)
PT (1) PT1051193E (el)
TW (1) TW590777B (el)
WO (1) WO2000033877A1 (el)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179475B1 (en) 1998-12-04 2007-02-20 Johnson & Johnson Consumer Companies, Inc. Anhydrous topical skin preparations
US6579570B1 (en) * 2000-05-04 2003-06-17 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6423804B1 (en) 1998-12-31 2002-07-23 Kimberly-Clark Worldwide, Inc. Ion-sensitive hard water dispersible polymers and applications therefor
US6713414B1 (en) 2000-05-04 2004-03-30 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
AU2001247264B2 (en) * 2000-03-03 2005-08-18 Australian Importers, Ltd. Micronized vitamin C formulation
US7101563B1 (en) 2000-03-03 2006-09-05 Australian Importers, Ltd. Micronized vitamin C formulation
US6537663B1 (en) 2000-05-04 2003-03-25 Kimberly-Clark Worldwide, Inc. Ion-sensitive hard water dispersible polymers and applications therefor
US6653406B1 (en) 2000-05-04 2003-11-25 Kimberly Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6599848B1 (en) 2000-05-04 2003-07-29 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6835678B2 (en) 2000-05-04 2004-12-28 Kimberly-Clark Worldwide, Inc. Ion sensitive, water-dispersible fabrics, a method of making same and items using same
US6429261B1 (en) 2000-05-04 2002-08-06 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6548592B1 (en) 2000-05-04 2003-04-15 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6444214B1 (en) 2000-05-04 2002-09-03 Kimberly-Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6410036B1 (en) * 2000-05-04 2002-06-25 E-L Management Corp. Eutectic mixtures in cosmetic compositions
US6683143B1 (en) 2000-05-04 2004-01-27 Kimberly Clark Worldwide, Inc. Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US7897559B2 (en) * 2000-06-29 2011-03-01 Parks L Dean Dermatological composition and kit containing avermectin compound for treating dermatological conditions
AU2001274420A1 (en) * 2000-07-11 2002-01-21 Micio Pharma Chemical Ag Anhydrous pharmaceutical composition of vancomycin for topical use
US6475526B1 (en) * 2001-06-05 2002-11-05 Jeffrey B. Smith Zinc containing compositions for anti-viral use
US20030199488A1 (en) * 2002-04-23 2003-10-23 Trotta Gina M. Treatment of hyperproliferative disorders/inflammatory dermatoses
US7005408B2 (en) * 2002-05-01 2006-02-28 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
ATE396705T1 (de) * 2002-05-01 2008-06-15 Mcneil Ppc Inc Erwärmende und nicht irritierende antifungale schmiermittelzubereitung in gelform
US7772138B2 (en) 2002-05-21 2010-08-10 Kimberly-Clark Worldwide, Inc. Ion sensitive, water-dispersible polymers, a method of making same and items using same
US7101456B2 (en) * 2002-09-20 2006-09-05 Kimberly-Clark Worldwide, Inc. Ion triggerable, cationic polymers, a method of making same and items using same
US7141519B2 (en) * 2002-09-20 2006-11-28 Kimberly-Clark Worldwide, Inc. Ion triggerable, cationic polymers, a method of making same and items using same
US20040058600A1 (en) * 2002-09-20 2004-03-25 Bunyard W. Clayton Water-dispersible, cationic polymers, a method of making same and items using same
US6960371B2 (en) * 2002-09-20 2005-11-01 Kimberly-Clark Worldwide, Inc. Water-dispersible, cationic polymers, a method of making same and items using same
US6994865B2 (en) * 2002-09-20 2006-02-07 Kimberly-Clark Worldwide, Inc. Ion triggerable, cationic polymers, a method of making same and items using same
US7157389B2 (en) * 2002-09-20 2007-01-02 Kimberly-Clark Worldwide, Inc. Ion triggerable, cationic polymers, a method of making same and items using same
US8232304B2 (en) * 2002-10-24 2012-07-31 G & R Pharmaceuticals, Llc Antifungal formulations
US7241456B2 (en) * 2002-10-25 2007-07-10 Australian Importers Ltd. Formulations for topical delivery of bioactive substances and methods for their use
US20080274209A1 (en) * 2002-11-04 2008-11-06 Integritas Pharma, Inc. Methods of treating inflammation
US20060229258A1 (en) * 2003-07-30 2006-10-12 Daniela Serikaku Steroidal compositions containing hydroxycarboxylic acids and methods of using the same
JP4660378B2 (ja) * 2003-12-26 2011-03-30 久光製薬株式会社 外用非水系ゲル製剤
JP5324091B2 (ja) * 2004-06-24 2013-10-23 アイデックス ラボラトリーズ,インコーポレイティド 薬物送達のための医薬組成物及びそれを使用する症状の治療又は予防法
US7618651B2 (en) * 2004-06-24 2009-11-17 Idexx Laboratories Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
US7854943B2 (en) * 2004-06-24 2010-12-21 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
US7858115B2 (en) * 2004-06-24 2010-12-28 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
EP3556401A1 (en) 2005-05-27 2019-10-23 The University of North Carolina at Chapel Hill Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications
CA2623725A1 (en) * 2005-09-30 2007-04-12 Omp, Inc. Stable ascorbic acid compositions
US20070269534A1 (en) * 2006-02-02 2007-11-22 Ramirez Jose E Methods of treating skin to enhance therapeutic treatment thereof
US20070178058A1 (en) * 2006-02-02 2007-08-02 Ramirez Jose E Methods of using stable ascorbic acid compositions
US20080146672A1 (en) * 2006-12-08 2008-06-19 Denton Marcia Marye Topical Eutectic Anesthetic Composition for Oral or Dermal Tissue
FR2931661B1 (fr) * 2008-05-30 2010-07-30 Galderma Res & Dev Nouvelles compositions depigmentantes sous forme d'une composition anhydre sans vaseline et sans elastomere comprenant un derive phenolique solubilise et un retinoide.
JP5978130B2 (ja) 2009-08-14 2016-08-24 バーグ エルエルシー 脱毛症を治療するためのビタミンd3およびその類似体
WO2011022652A1 (en) 2009-08-21 2011-02-24 Novan, Inc. Topical gels
BR112012003804B1 (pt) 2009-08-21 2019-02-19 Novan, Inc. Curativo para ferimentos, método para formar um curativo para ferimentos, e, kit de curativo para ferimento
MX2012006661A (es) 2009-12-08 2012-11-12 Healthpoint Ltd Composiciones enzimaticas de desbridamiento de heridas con actividad enzimatica mejorada.
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
WO2012118829A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Tertiary s-nitrosothiol-modified nitricoxide-releasing xerogels and methods of using the same
WO2012158405A2 (en) * 2011-05-16 2012-11-22 Pearlman Dale L Compositions and methods for the treatment of skin diseases
ES2804263T3 (es) * 2011-07-05 2021-02-05 Novan Inc Composiciones tópicas
WO2013006613A1 (en) 2011-07-05 2013-01-10 Novan, Inc. Methods of manufacturing topical compositions and apparatus for same
US9439940B2 (en) * 2011-07-19 2016-09-13 Neville Pharmaceutical, Inc. Topical transdermal method for delivering nutrients through the skin for expeditied wound healing and skin rejuvenation
US9855211B2 (en) 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
EP3166593B1 (en) 2014-07-11 2020-05-20 Novan, Inc. Topical antiviral compositions and methods of using the same
US10322082B2 (en) 2014-07-11 2019-06-18 Novan, Inc. Topical antiviral compositions and methods of using the same
BR112018070578A2 (pt) 2016-04-13 2019-02-12 Novan, Inc. composições, sistemas, kits, e métodos para tratar uma infecção
WO2018129364A1 (en) * 2017-01-06 2018-07-12 Palvella Therapeutics Llc Anhydrous compositions of mtor inhibitors and methods of use
JP2020533155A (ja) * 2017-09-21 2020-11-19 ザ プロクター アンド ギャンブル カンパニーThe Procter & Gamble Company 吸収性物品
WO2020010073A1 (en) 2018-07-02 2020-01-09 Palvella Therapeutics, Inc. ANHYDROUS COMPOSITIONS OF mTOR INHIBITORS AND METHODS OF USE
KR20200028242A (ko) 2018-09-06 2020-03-16 경동산업(주) 분배기와, 분배기를 가공하는 장치
KR102219279B1 (ko) 2018-09-06 2021-02-24 경동산업(주) 분배기를 가공하는 방법
KR102165478B1 (ko) 2018-10-24 2020-10-14 경동산업(주) 냉풍 건조장치
WO2020242715A1 (en) 2019-05-31 2020-12-03 The Procter & Gamble Company Absorbent article having a waist gasketing element
KR102240394B1 (ko) 2019-07-09 2021-04-14 경동산업(주) 저온 냉동 창고의 냉장과 제상 동시 운전 시스템
CA3155267A1 (en) * 2019-11-06 2021-05-14 Thomas Hnat Topical formulations of cyclooxygenase inhibitors and their use
CN115484909A (zh) 2020-05-05 2022-12-16 宝洁公司 包括改进的弹性片的吸收制品
AT524069A1 (de) 2020-07-30 2022-02-15 Hans L Malzl System und verfahren zur erfassung der schlafqualität

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3729568A (en) 1969-09-23 1973-04-24 Johnson & Johnson Acne treatment
US3943013A (en) * 1973-10-11 1976-03-09 General Electric Company Triac with gold diffused boundary
US3934028A (en) 1974-04-22 1976-01-20 The Regents Of The University Of California Acne and psoriasis treatment with retinoic acid analogs
SE7612936L (sv) 1976-11-19 1978-05-20 Pharmacia Ab Hygienisk-kosmetiska kompositioner
US4247547A (en) 1979-03-19 1981-01-27 Johnson & Johnson Tretinoin in a gel vehicle for acne treatment
US4942162A (en) 1982-03-31 1990-07-17 University Of Tennessee Research Corporation Topical treatment of seborrheic dermatitis with ketoconazole
US4491588A (en) 1982-03-31 1985-01-01 University Of Tennessee Research Corporation Treatment of psoriasis and seborrheic dermatitis with imidazole antibiotics
US4569935A (en) 1983-03-17 1986-02-11 University Of Tennessee Research Corp. Topical treatment of psoriasis with imidazole antibiotics
JPS62292716A (ja) * 1986-06-11 1987-12-19 Kao Corp 消炎軟膏剤
US4782059A (en) 1986-09-29 1988-11-01 Merck & Co., Inc. Method of controlling mycotic infections and compositions therefor
EP0303713B2 (en) * 1987-02-23 1997-07-30 Shiseido Company Limited Percutaneous absorption promoter and dermatologic preparation for external use
US5110809A (en) 1988-03-21 1992-05-05 Bristol-Myers Squibb Company Antifungal gel formulations
US5002938A (en) * 1988-03-21 1991-03-26 Bristol-Myers Squibb Company Antifungal gel formulations
US4855294A (en) 1988-09-06 1989-08-08 Theratech, Inc. Method for reducing skin irritation associated with drug/penetration enhancer compositions
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
US4988697A (en) 1989-07-28 1991-01-29 Merck & Co., Inc. Fungicidal compositions and method
US5061700A (en) * 1989-11-16 1991-10-29 Gordon Jay Dow Glyceryl acetate ointment vehicles
US5583136A (en) 1990-01-29 1996-12-10 Johnson & Johnson Consumer Products, Inc. Retinoid containing skin care compositions containing imidazoles
US5087620A (en) 1990-05-17 1992-02-11 Bristol-Myers Squibb Co. Controlled dermal penetration enhancement using imidazoles
US5310545A (en) 1991-04-11 1994-05-10 Drore Eisen Method of treatment using mouthwashes containing steroids and antifungal agents and compositions of matter
US5407663A (en) 1991-04-11 1995-04-18 Eisen; Drore Method of treating inflammatory conditions of the mouth using steroid containing mouthwash which may contain antifungal agents
FR2676052B1 (fr) * 1991-05-02 1994-04-29 Cird Galderma Nouveaux composes polycycliques aromatiques et leur utilisation en medecine humaine ou veterinaire et en cosmetique.
US5208015A (en) 1991-07-23 1993-05-04 Bristol-Myers Squibb Company Topical anti-fungal agents having anti-inflammatory activity
ES2098921T3 (es) 1993-01-21 1997-05-01 Janssen Pharmaceutica Nv Composiciones de cetoconazol de uso topico.
TW297813B (el) 1993-09-24 1997-02-11 Takeda Pharm Industry Co Ltd
US5456851A (en) 1994-04-07 1995-10-10 Johnson & Johnson Consumer Products, Inc. Ketoconazole shampoo containing butylated hydroxytoluene or butylated hydroxyanisole
TW460296B (en) * 1994-09-01 2001-10-21 Janssen Pharmaceutica Nv Topical ketoconazole emulsion compositions without sodium sulfite
EP0729745A1 (en) * 1995-02-28 1996-09-04 Unilever Plc Vitamin C delivery system
US5993787A (en) 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations

Also Published As

Publication number Publication date
DE69930004T2 (de) 2006-10-12
EP1645287A3 (en) 2006-06-07
PT1051193E (pt) 2006-06-30
CN100341578C (zh) 2007-10-10
AU1841200A (en) 2000-06-26
EP1051193B1 (en) 2006-02-22
TW590777B (en) 2004-06-11
DK1051193T3 (da) 2006-06-12
ES2258347T3 (es) 2006-08-16
JP2002531526A (ja) 2002-09-24
HK1031342A1 (en) 2001-06-15
CN1714869A (zh) 2006-01-04
CA2319515A1 (en) 2000-06-15
CA2319515C (en) 2009-10-13
DE69930004D1 (de) 2006-04-27
US6238683B1 (en) 2001-05-29
BR9907666A (pt) 2000-12-19
KR100619228B1 (ko) 2006-09-04
CN1292707A (zh) 2001-04-25
WO2000033877A1 (en) 2000-06-15
ATE318148T1 (de) 2006-03-15
AR021539A1 (es) 2002-07-24
AU778524B2 (en) 2004-12-09
JP4610741B2 (ja) 2011-01-12
CN1204923C (zh) 2005-06-08
AU2005201042A1 (en) 2005-04-07
EP1051193A1 (en) 2000-11-15
EP1645287A2 (en) 2006-04-12
KR20010040573A (ko) 2001-05-15

Similar Documents

Publication Publication Date Title
CY1105450T1 (el) Ανυδρο τοπικο δepματικο παρασκευασμα πepιεχον κετοκοναζολη
ES2620413T3 (es) Formulaciones veterinarias antihelmínticas tópicas
ES2323137T3 (es) Composicion antiparasitaria que contiene una sal de amina organica de closantel.
CY1109843T1 (el) Αναλογα της βιταμινης d
BR9912694A (pt) Composto para preparar medicamento de administração pulmonar
ES2185999T3 (es) Derivados de quinazolina y composiciones farmaceuticas que los contienen.
FI914391A0 (fi) Sammansaettningar vilka foerstaerker hudens permeabilitet.
CY1108070T1 (el) Παραγωγα κινολινονης, ως αναστολεις κινασης τυροσινης
ATE235895T1 (de) Arzneistoff-abgabesystem enthaltend eine festgepackte, feste arzneistoffbasis
CY1111698T1 (el) Συνδυασμος που περιλαμβανει εναν ανταγωνιστη υποδοχεα ατ1 και εναν ενισχυτη εκκρισης ινσουλινης ή εναν ευαισθητοποιητη ινσουλινης
AR098745A2 (es) Composición, kit y uso de compuestos quimioterapéuticos
PT1272199E (pt) Terapias de combinacao com actividade de lesao vascular
TR200401603T4 (tr) D vitamini benzerleri
KR960704543A (ko) 악성 질환의 치료를 위한 비경구투여용 부설판(Parenteral Busulfan for treatment of malignant disease)
TR199900336T2 (xx) EAA antagonistleri olarak tetrahidrokinolin t�revleri.
RU2009123536A (ru) Стабильные парентеральные составы, включающие ингибиторы pcb на основе бензодиазепина
AR043071A1 (es) Uso de macrolidos para el tratamiento del cancer y degeneracion macular y una composicion farmaceutica
EA200101241A1 (ru) Производные индола
HK1039567A1 (en) Anhydrous topical skin preparations
EA200500082A1 (ru) Фармацевтическая композиция для чрескожной доставки физиологически активных агентов
AR031846A1 (es) Combinacion de sustancias activas, medicamentos y formulaciones que la contienen, y uso de la misma para la preparacion de un medicamento para el tratamiento del dolor
TH48062B (th) ส่วนเตรียมแอนไฮดรัสใช้เฉพาะผิวหนัง
IT1204778B (it) Formulazioni farmaceutiche iniettabili di principi attivi ad attivita' anestetica generale
TH48062A3 (th) ส่วนเตรียมแอนไฮดรัสใช้เฉพาะผิวหนัง
ATE306941T1 (de) Gesteigerte abgabe von auf nukleinsäuren basierenden arzneimitteln