CY1105040T1 - Συνεχης μεθοδος δια την παρασκευην παραγωγων σουλφανικης φρουκτοπυραζονης - Google Patents

Συνεχης μεθοδος δια την παρασκευην παραγωγων σουλφανικης φρουκτοπυραζονης

Info

Publication number
CY1105040T1
CY1105040T1 CY20061100703T CY061100703T CY1105040T1 CY 1105040 T1 CY1105040 T1 CY 1105040T1 CY 20061100703 T CY20061100703 T CY 20061100703T CY 061100703 T CY061100703 T CY 061100703T CY 1105040 T1 CY1105040 T1 CY 1105040T1
Authority
CY
Cyprus
Prior art keywords
preparation
derivatives
fructopyrazone
sulphanic
continuous method
Prior art date
Application number
CY20061100703T
Other languages
English (en)
Inventor
Thomas W. Adkins
Charles F. Cicco
Penina Feibush
Donald A. Koch
Cynthia Maryanoff
Walter E. Stalzer
Original Assignee
Ortho-Mcneil Pharmaceutical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Mcneil Pharmaceutical, Inc. filed Critical Ortho-Mcneil Pharmaceutical, Inc.
Publication of CY1105040T1 publication Critical patent/CY1105040T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Η παρούσα εφεύρεσις αναφέρεται εις συνεχή μέθοδον δια την παρασκευήν παραγώγων σουλφανικής φρουκτοπυρανόζης του γενικού τύπου (I), εις τον οποίον τα R1, R3, R4, R5, R6 και X είναι ως καθορίζονται ενταύθα. Η παρούσα εφεύρεσις περαιτέρω αναφέρεται εις συνεχή μέθοδον δια την παρασκευήν Τοπιραμάτης (Topiramate).
CY20061100703T 2002-10-31 2006-06-01 Συνεχης μεθοδος δια την παρασκευην παραγωγων σουλφανικης φρουκτοπυραζονης CY1105040T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42255802P 2002-10-31 2002-10-31
US10/691,782 US7196209B2 (en) 2002-10-31 2003-10-23 Continuous process for the preparation of fructopyranose sulfamate derivatives
PCT/US2003/034107 WO2004041836A1 (en) 2002-10-31 2003-10-27 Continuous process for the preparation of fructopyranose sulfamate derivatives

Publications (1)

Publication Number Publication Date
CY1105040T1 true CY1105040T1 (el) 2010-03-03

Family

ID=32314459

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061100703T CY1105040T1 (el) 2002-10-31 2006-06-01 Συνεχης μεθοδος δια την παρασκευην παραγωγων σουλφανικης φρουκτοπυραζονης

Country Status (23)

Country Link
US (1) US7196209B2 (el)
EP (1) EP1558624B1 (el)
JP (1) JP4892191B2 (el)
KR (1) KR20050083838A (el)
AR (1) AR041742A1 (el)
AT (1) ATE320440T1 (el)
AU (1) AU2003285014A1 (el)
BR (1) BR0315892A (el)
CA (1) CA2504039A1 (el)
CY (1) CY1105040T1 (el)
DE (1) DE60304060T2 (el)
DK (1) DK1558624T3 (el)
ES (1) ES2260673T3 (el)
HR (1) HRP20050370A2 (el)
MX (1) MXPA05004647A (el)
MY (1) MY137066A (el)
NO (1) NO20052593D0 (el)
NZ (1) NZ539506A (el)
PL (1) PL376538A1 (el)
PT (1) PT1558624E (el)
RU (1) RU2317301C2 (el)
TW (1) TW200418867A (el)
WO (1) WO2004041836A1 (el)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5643844B2 (ja) * 2010-02-05 2014-12-17 サイノファーム タイワン リミテッド トピラマート（ｔｏｐｉｒａｍａｔｅ）の製造方法
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513006A (en) * 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
AU651244B2 (en) * 1991-09-19 1994-07-14 Mcneilab, Inc. Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3:4,5-bis-0-(1-methylethylidene)-beta-D- fructopyranose and (1-methylcyclohexyl)methanol
US5242942A (en) * 1992-04-28 1993-09-07 Mcneilab, Inc. Anticonvulsant fructopyranose cyclic sulfites and sulfates

Also Published As

Publication number Publication date
MY137066A (en) 2008-12-31
WO2004041836A1 (en) 2004-05-21
ATE320440T1 (de) 2006-04-15
HRP20050370A2 (en) 2006-07-31
MXPA05004647A (es) 2005-09-20
NO20052593L (no) 2005-05-30
US20040158081A1 (en) 2004-08-12
BR0315892A (pt) 2005-10-04
CA2504039A1 (en) 2004-05-21
KR20050083838A (ko) 2005-08-26
DE60304060D1 (de) 2006-05-11
AU2003285014A1 (en) 2004-06-07
TW200418867A (en) 2004-10-01
ES2260673T3 (es) 2006-11-01
US7196209B2 (en) 2007-03-27
DE60304060T2 (de) 2006-09-28
AR041742A1 (es) 2005-05-26
JP2006508949A (ja) 2006-03-16
PT1558624E (pt) 2006-05-31
RU2005113268A (ru) 2006-01-20
NO20052593D0 (no) 2005-05-30
JP4892191B2 (ja) 2012-03-07
EP1558624A1 (en) 2005-08-03
DK1558624T3 (da) 2006-05-15
RU2317301C2 (ru) 2008-02-20
NZ539506A (en) 2007-06-29
EP1558624B1 (en) 2006-03-15
PL376538A1 (pl) 2006-01-09

Similar Documents

Publication Publication Date Title
CY1108456T1 (el) Ενωσεις βενζιμιδαζολονης
TW200504089A (en) One step process for the preparation of anticonvulsant derivatives
CY1108454T1 (el) Ενωσεις σπειροπυραζολιου
BR9914814A (pt) Processo para a preparação de luteolina e derivados de luteolina
DE69817802D1 (de) Substituierte phenylderivate, ihre herstellung und verwendung
CY1108707T1 (el) Αναλογα νοσισεπτινης
CY1106003T1 (el) Παραγωγα του ν-βενζοϋλοουρεϊδο-κινναμωμικου οξεος, μεθοδος για την παρασκευη τους και η χρηση τους
UA86760C2 (ru) Замещенные n-арилгетероциклы, способ их получения и их применение в качестве лекарственных средств
RS115004A (en) Novel thiophenylglycoside derivatives,methods for production thereof, medicaments comprising said compounds and use thereof
CY1107851T1 (el) Παραγωγα πυρολλο-πυριδινης και η χρηση τους ως ανταγωνιστων crth2
CY1105617T1 (el) Νεα αρωματικα παραγωγα των φθορογλυκοσιδων, φαρμακα περιεχοντα αυτες τις ενωσεις και η χρηση τους
TNSN04199A1 (en) Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use
MXPA03008754A (es) Derivados de piridina fundidos para utilizarse como agonistas receptores vaniloide para tratar dolor.
EA200600621A1 (ru) Производные тетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств
PT923554E (pt) N-benzilpiperidina e derivados tetrahidropiridina
TR199800608A2 (en) Propanolamin t�revleri, bunlar�n �retim usul�.
DK1127886T3 (da) Syntese af 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2-on
CY1106376T1 (el) Δικυκλικα παραγωγα των αμινο-πυραζινονων, μεθοδος παρασκευης τους και οι φαρμακευτικες συνθεσεις που τα πepιεχουν
DE60239468D1 (de) Amphotere lipidverbindung und deren verwendung
CY1105040T1 (el) Συνεχης μεθοδος δια την παρασκευην παραγωγων σουλφανικης φρουκτοπυραζονης
TR200302288T2 (tr) Terapi için yeni bileşikler ve metotlar.
CY1112050T1 (el) Νεα 2-αλογονοποιημενα παραγωγα της 5-0- δεσοσαμινυλερυθρονολιδης α, η διαδικασια της παρασκευης τους και η εφαρμογη τους ως φαρμακευτικα προϊοντα
RS88704A (en) Acyl-3-carboxyphenylurea derivatives, method for production and use thereof
CY1106317T1 (el) Παραγωγα 1-ν-φαινυλαμινο-1η-ιμιδαζολης, ως αναστολεις αρωματασης
ES2185196T3 (es) Un procedimiento para la preparacion de tetraazamacrociclos.