CU24686B1 - Composición de vacuna contra la hepatitis b, proceso de obtención de dicha composición y sistema de rinovacunación para prevenir y tratar la hepatitis b - Google Patents

Composición de vacuna contra la hepatitis b, proceso de obtención de dicha composición y sistema de rinovacunación para prevenir y tratar la hepatitis b

Info

Publication number
CU24686B1
CU24686B1 CU2020000097A CU20200097A CU24686B1 CU 24686 B1 CU24686 B1 CU 24686B1 CU 2020000097 A CU2020000097 A CU 2020000097A CU 20200097 A CU20200097 A CU 20200097A CU 24686 B1 CU24686 B1 CU 24686B1
Authority
CU
Cuba
Prior art keywords
hepatitis
prevent
composition
rinovacination
obtaining
Prior art date
Application number
CU2020000097A
Other languages
English (en)
Other versions
CU20200097A7 (es
Inventor
Rubido Julio Cesar Aguilar
Nieto Gerardo Enrique Guillen
Yoichi Hiasa
Taizou Kamishita
Takashi Miyazaki
Arias Eduardo Penton
Mohammad Fazle Akbar Sheikh
Osamu Yoshida
Original Assignee
Ct Ingenieria Genetica Biotecnologia
Univ Nat Corp Ehime Univ
Toko Yakuhin Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Ingenieria Genetica Biotecnologia, Univ Nat Corp Ehime Univ, Toko Yakuhin Kogyo Kk filed Critical Ct Ingenieria Genetica Biotecnologia
Publication of CU20200097A7 publication Critical patent/CU20200097A7/es
Publication of CU24686B1 publication Critical patent/CU24686B1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/34Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl
    • B05B1/3405Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02Membranes or pistons acting on the contents inside the container, e.g. follower pistons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

<p>La presente invención se refiere a una composición de vacuna contra la hepatitis B, caracterizada porque comprende un antígeno de superficie de la hepatitis B y/o un antígeno de nucleocápside de la hepatitis B, y un material a base de gel que comprende polímero de carboxivinilo. La invención se refiere además a un proceso para preparar dicha composición vacunal y a un sistema de rinovacunación para prevenir y tratar la hepatitis B como se muestra en la figura 1.</p>
CU2020000097A 2018-06-05 2019-06-04 Composición de vacuna contra la hepatitis b, proceso de obtención de dicha composición y sistema de rinovacunación para prevenir y tratar la hepatitis b CU24686B1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018107797 2018-06-05
PCT/JP2019/022136 WO2019235466A1 (ja) 2018-06-05 2019-06-04 B型肝炎ワクチン経鼻投与システム

Publications (2)

Publication Number Publication Date
CU20200097A7 CU20200097A7 (es) 2021-07-02
CU24686B1 true CU24686B1 (es) 2023-11-07

Family

ID=68769323

Family Applications (1)

Application Number Title Priority Date Filing Date
CU2020000097A CU24686B1 (es) 2018-06-05 2019-06-04 Composición de vacuna contra la hepatitis b, proceso de obtención de dicha composición y sistema de rinovacunación para prevenir y tratar la hepatitis b

Country Status (15)

Country Link
US (1) US12070497B2 (es)
EP (1) EP3804752A4 (es)
JP (1) JPWO2019235466A1 (es)
KR (1) KR20210022009A (es)
CN (1) CN112368018A (es)
AU (1) AU2019283122A1 (es)
BR (1) BR112020022784A2 (es)
CA (1) CA3099430A1 (es)
CU (1) CU24686B1 (es)
IL (1) IL278415B2 (es)
MX (1) MX2020013240A (es)
PH (1) PH12020552075A1 (es)
SG (1) SG11202011004RA (es)
TW (1) TW202002950A (es)
WO (1) WO2019235466A1 (es)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19851282A1 (de) * 1998-11-06 2000-05-11 Schweiz Serum & Impfinst Zusammensetzung einer pharmazeutisch wirksamen Substanz, appliziert in einem spezifischen Delivery-System zur Prävention und Behandlung von Infektions-Krankheiten
US20030180351A1 (en) 1998-11-06 2003-09-25 Reinhard Gluck Pharmaceutically active composition and dispensing device
CU22871A1 (es) 1998-12-02 2003-10-21 Ct Ingenieria Genetica Biotech Formulaciones conteniendo partículas semejantes a virus como inmunopotenciadores por vía mucosal
WO2002080648A2 (en) * 2001-04-05 2002-10-17 Chiron Corporation Mucosal boosting following parenteral priming
EP1913378A1 (de) 2005-07-29 2008-04-23 Sigma-Aldrich Production GmbH Ionisierungsadditive enthaltende lc/ms-blends
RU2434652C2 (ru) 2006-04-21 2011-11-27 Токо Якухин Когио Кабусики Кайся Емкость для текучей среды и система безвоздушного дозирования текучей среды с использованием упомянутой емкости
WO2010114169A1 (en) 2009-03-31 2010-10-07 Japan As Represented By The Director-General Of National Institute Of Infectious Diseases Method for prophylaxis of influenza using vaccine for intranasal administration
CN104470642B (zh) 2012-03-30 2017-04-26 株式会社吉野工业所 计量注射器型喷射器
JP6322844B2 (ja) * 2014-06-25 2018-05-16 東興薬品工業株式会社 医療用シリンジに用いられる点鼻用噴霧ノズル
CN106573045B (zh) * 2014-06-25 2020-10-27 东兴药品工业株式会社 流感疫苗经鼻接种系统
RU2603729C2 (ru) 2015-04-24 2016-11-27 Закрытое акционерное общество научно-производственная компания "Комбиотех" Рекомбинантная вакцина для профилактики вирусного гепатита в (варианты)
JP6558392B2 (ja) * 2017-04-04 2019-08-14 ニプロ株式会社 シリンジ型噴出装置

Also Published As

Publication number Publication date
JPWO2019235466A1 (ja) 2021-06-24
US12070497B2 (en) 2024-08-27
TW202002950A (zh) 2020-01-16
IL278415B1 (en) 2023-06-01
EP3804752A4 (en) 2022-03-09
SG11202011004RA (en) 2020-12-30
CU20200097A7 (es) 2021-07-02
AU2019283122A1 (en) 2020-11-26
KR20210022009A (ko) 2021-03-02
IL278415A (es) 2020-12-31
MX2020013240A (es) 2021-05-12
CA3099430A1 (en) 2019-12-12
BR112020022784A2 (pt) 2021-02-02
PH12020552075A1 (en) 2021-05-31
US20210187101A1 (en) 2021-06-24
EP3804752A1 (en) 2021-04-14
WO2019235466A1 (ja) 2019-12-12
CN112368018A (zh) 2021-02-12
IL278415B2 (en) 2023-10-01

Similar Documents

Publication Publication Date Title
BR112018013930A2 (pt) vírus oncolítico, vírus que expressa três genes heterólogos, composição farmacêutica, vírus para o uso, produto de fabricação, método de tratamento de câncer e uso do vírus
AR102657A1 (es) Composición para tratar telas
CL2018000827A1 (es) Tetrahidro-1h-pirido[3, 4-b] indol fármacos antiestrogénicos
MX2018010586A (es) Nanovacuna de activacion de &#34;sting&#34; para inmunoterapia.
BR112018004242A2 (pt) composições de vacina que possuem estabilidade e imunogenicidade aumentadas
MX2020004542A (es) Metodo para inactivar el virus del zika y para determinar la inactivacion total.
MX2021006681A (es) Anticuerpos anti-claudina y usos de los mismos.
PH12017501370A1 (en) Bivalent swine influenza virus vaccine
PH12019500624A1 (en) Swine comprising modified cd163 and associated methods
PH12018000197A1 (en) Hand, foot, and mouth vaccines and methods of manufacture and use thereof
EA201990010A1 (ru) Вакцина против вируса инфекционного бронхита
BR112017006511A2 (pt) método para produção de uma manta de espuma
MX2020004633A (es) Metodo para inactivar el virus de zika y metodos relacionados.
MX2019005102A (es) Poxvirus quimericos sinteticos.
PH12018501154A1 (en) Attenuated infectious bronchitis virus
AU2017261705A1 (en) Inorganic polyatomic oxyanions for protecting against antigenic damage during pathogen inactivation for vaccine production
CY1125031T1 (el) Μεθοδος για γενετικη θεραπεια χρησιμοποιωντας τον ιο aav-xbp1s/gfp και χρηση αυτης στην προληψη και τη θεραπεια της αμυοτροφικης πλευρικης σκληρυνσης
BR112016015078A2 (pt) método para prevenir ou tratar infecção por vírus influenza a h7n9, uso do anticorpo e composição farmacêutica
MX2018014955A (es) Vacunas atenuadas vivas del virus de la influenza equina.
AR104271A1 (es) Vacuna contra las paperas en base al virus jeryl lynn 2 recombinante
MX2017015004A (es) Estrategia de vacuna basada en nanoparticulas contra el virus de la influenza porcina.
CU24686B1 (es) Composición de vacuna contra la hepatitis b, proceso de obtención de dicha composición y sistema de rinovacunación para prevenir y tratar la hepatitis b
CL2020002876A1 (es) Vacuna contra la bronquitis infecciosa (divisional de la solicitud no. 201803420)
UY36208A (es) “bacterias modificadas para vacunas mejoradas contra la brucelosis”.
CO2018012295A2 (es) Antígenos y anticuerpos de chagas y composiciones, métodos y sus usos