CS95185A2 - Zpusob vyroby novych karbacyklinu - Google Patents

Zpusob vyroby novych karbacyklinu

Info

Publication number
CS95185A2
CS95185A2 CS95185A CS95185A CS95185A2 CS 95185 A2 CS95185 A2 CS 95185A2 CS 95185 A CS95185 A CS 95185A CS 95185 A CS95185 A CS 95185A CS 95185 A2 CS95185 A2 CS 95185A2
Authority
CS
Czechoslovakia
Prior art keywords
group
alkyl
image
karbacyklinu
3bond
Prior art date
Application number
CS95185A
Other languages
English (en)
Other versions
CS252481B2 (en
Inventor
Werner Dr Skuballa
Bernd Dr Raduechel
Helmut Prof Vorbrueggen
Robert Dr Nickolson
Martin Dr Haberey
Olaf Dr Loge
Claus-Steffen Dr Stuerzebecher
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of CS95185A2 publication Critical patent/CS95185A2/cs
Publication of CS252481B2 publication Critical patent/CS252481B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Ink Jet Recording Methods And Recording Media Thereof (AREA)
  • Drawers Of Furniture (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CS85951A 1984-02-10 1985-02-11 Method of new carbacyclines production CS252481B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843405181 DE3405181A1 (de) 1984-02-10 1984-02-10 Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
CS95185A2 true CS95185A2 (en) 1987-01-15
CS252481B2 CS252481B2 (en) 1987-09-17

Family

ID=6227657

Family Applications (1)

Application Number Title Priority Date Filing Date
CS85951A CS252481B2 (en) 1984-02-10 1985-02-11 Method of new carbacyclines production

Country Status (19)

Country Link
US (1) US4721729A (cs)
EP (1) EP0153274B1 (cs)
JP (1) JPS60188336A (cs)
AT (1) ATE52770T1 (cs)
AU (1) AU567205B2 (cs)
CS (1) CS252481B2 (cs)
DD (1) DD233997A5 (cs)
DE (2) DE3405181A1 (cs)
DK (1) DK56285A (cs)
ES (1) ES540264A0 (cs)
FI (1) FI850519L (cs)
GR (1) GR850351B (cs)
HU (1) HU192316B (cs)
IE (1) IE850305L (cs)
IL (1) IL74280A0 (cs)
NO (1) NO160846C (cs)
NZ (1) NZ211048A (cs)
PH (1) PH23082A (cs)
ZA (1) ZA85985B (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
DE3638761A1 (de) * 1986-11-13 1988-05-26 Schering Ag Verbesserte ketoreduktion von carbacyclinzwischenprodukten
ATE386531T1 (de) * 1997-02-28 2008-03-15 Nycomed Gmbh Synergistische kombination von pde-hemmern und adenylatcyclase-agonisten bzw. guanylcyclyse- agonisten

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7605381A (nl) * 1975-05-26 1976-11-30 Schering Ag Werkwijze voor het bereiden van prostaanderi- vaten en werkwijze voor het bereiden van een geneesmiddel met prostaglandinewerking.
GB2013661B (en) * 1978-01-26 1982-11-10 Erba Farmitalia 9-deoxy-9 -methylene isosteres of pgi2
US4123463A (en) * 1978-03-21 1978-10-31 The Upjohn Company 2-Decarboxy-2-alkylketone prostaglandins
DE3121155A1 (de) * 1981-05-22 1982-12-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3225287A1 (de) * 1982-07-02 1984-01-05 Schering AG, 1000 Berlin und 4709 Bergkamen Neue carbacyclinamide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3226550A1 (de) * 1982-07-13 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
ES8601835A1 (es) 1985-12-01
DD233997A5 (de) 1986-03-19
CS252481B2 (en) 1987-09-17
HU192316B (en) 1987-05-28
DK56285D0 (da) 1985-02-07
ATE52770T1 (de) 1990-06-15
FI850519A0 (fi) 1985-02-07
NO160846B (no) 1989-02-27
JPS60188336A (ja) 1985-09-25
EP0153274A1 (de) 1985-08-28
US4721729A (en) 1988-01-26
NO160846C (no) 1989-06-07
DE3577702D1 (de) 1990-06-21
DE3405181A1 (de) 1985-08-22
EP0153274B1 (de) 1990-05-16
FI850519A7 (fi) 1985-08-11
IL74280A0 (en) 1985-05-31
IE850305L (en) 1985-08-10
HUT36814A (en) 1985-10-28
NO850486L (no) 1985-08-12
FI850519L (fi) 1985-08-11
PH23082A (en) 1989-04-10
ZA85985B (en) 1985-09-25
ES540264A0 (es) 1985-12-01
NZ211048A (en) 1988-09-29
AU3861485A (en) 1985-08-15
DK56285A (da) 1985-08-11
GR850351B (cs) 1985-06-05
AU567205B2 (en) 1987-11-12

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