CS539788A2 - Method of n-substituted benzamides production - Google Patents

Method of n-substituted benzamides production

Info

Publication number
CS539788A2
CS539788A2 CS885397A CS539788A CS539788A2 CS 539788 A2 CS539788 A2 CS 539788A2 CS 885397 A CS885397 A CS 885397A CS 539788 A CS539788 A CS 539788A CS 539788 A2 CS539788 A2 CS 539788A2
Authority
CS
Czechoslovakia
Prior art keywords
production
substituted benzamides
benzamides
substituted
benzamides production
Prior art date
Application number
CS885397A
Other languages
English (en)
Other versions
CS272794B2 (en
Inventor
Armando V Noverola
Jose M P Soto
Fernando P Noguera
Jacinto M Mauri
Robert G W Spickett
Original Assignee
Fordonal Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fordonal Sa filed Critical Fordonal Sa
Publication of CS539788A2 publication Critical patent/CS539788A2/cs
Publication of CS272794B2 publication Critical patent/CS272794B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
CS539788A 1987-08-03 1988-08-01 Method of n-substituted benzamides production CS272794B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878718345A GB8718345D0 (en) 1987-08-03 1987-08-03 N-substituted benzamides

Publications (2)

Publication Number Publication Date
CS539788A2 true CS539788A2 (en) 1990-06-13
CS272794B2 CS272794B2 (en) 1991-02-12

Family

ID=10621740

Family Applications (1)

Application Number Title Priority Date Filing Date
CS539788A CS272794B2 (en) 1987-08-03 1988-08-01 Method of n-substituted benzamides production

Country Status (22)

Country Link
US (2) US4877780A (cs)
EP (1) EP0302699A3 (cs)
JP (1) JPS6450883A (cs)
KR (1) KR890003760A (cs)
CN (1) CN1031701A (cs)
AU (1) AU629175B2 (cs)
CS (1) CS272794B2 (cs)
DD (1) DD282010A5 (cs)
DK (1) DK429988A (cs)
FI (1) FI883592A7 (cs)
GB (1) GB8718345D0 (cs)
HU (1) HU200460B (cs)
IL (1) IL87080A (cs)
MX (1) MX12478A (cs)
NO (1) NO168422C (cs)
NZ (1) NZ225657A (cs)
PH (1) PH25048A (cs)
PL (1) PL154302B1 (cs)
PT (1) PT88175A (cs)
RO (1) RO101203B (cs)
SU (1) SU1739849A3 (cs)
ZA (1) ZA885418B (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820715A (en) * 1984-06-28 1989-04-11 Bristol-Myers Company Anti-emetic quinuclidinyl benzamides
EP0295350B1 (fr) * 1987-06-17 1992-11-11 Laboratoires DELAGRANGE Application du N-[2-(diethylamino)ethyl]2-methoxy 4-[(1-H 4,5-dihydro-2-imidazolyl) amino]5-chloro benzamide comme anxiolytique et anti-psychotique
FR2640139A1 (fr) * 1988-12-14 1990-06-15 Delagrange Laboratoires Application de benzamides substitues comme gastromoteurs
FR2640507A1 (fr) * 1988-12-20 1990-06-22 Delagrange Laboratoires Application de benzamides substitues comme anxiolytiques et anti-psychotiques
NZ241067A (en) * 1990-12-27 1993-03-26 Erba Carlo Spa Dihydrobenzofuran carboxamide derivatives, preparation and pharmaceutical compositions thereof
US5395832A (en) * 1991-02-15 1995-03-07 Hokuriku Seiyaku Co., Ltd. Benzamide derivatives
TW213460B (cs) * 1991-02-15 1993-09-21 Hokuriku Pharmaceutical
PH31171A (en) * 1992-02-04 1998-03-20 Esai Co Ltd Aminobenzonic acid derivatives useful for treatinggastrointestinal conditions.
US5236931A (en) * 1992-03-26 1993-08-17 A. H. Robins Company, Incorporated 2-substituted benzamide and benzoate derivatives of 3-aminoquinuclidine and 3-quinuclidinol
US5864039A (en) * 1994-03-30 1999-01-26 Yoshitomi Pharmaceutical Industries, Ltd. Benzoic acid compounds and use thereof as medicaments
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use
US6083991A (en) 1997-06-04 2000-07-04 University Of Florida Research Foundation, Inc. Anti-arrhythmic composition and methods of treatment
AR022338A1 (es) 1999-02-04 2002-09-04 Hokuriku Pharmaceutical Un compuesto de benzamida, medicamento que lo contiene, y uso para la manufactura de un medicamento para el tratamiento o prevencion de una enfermedad digestiva o para mejorar la movilidad del tracto gastrointestinal.
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US6486172B2 (en) 2000-08-18 2002-11-26 Pharmacia & Upjohn Company Quinuclidine-substituted aryl compounds for treatment of disease
EP1381603A2 (en) 2000-08-18 2004-01-21 PHARMACIA &amp; UPJOHN COMPANY Quinuclidine-substituedaryl moieties for treatment of disease ( nicotinic acetylcholine receptor ligands )
KR100381886B1 (ko) * 2001-03-21 2003-04-26 유니모씨엔티 주식회사 무선통신용 중계기의 씨디엠에이 신호 검출장치
PE20021019A1 (es) 2001-04-19 2002-11-13 Upjohn Co Grupos azabiciclicos sustituidos
CA2455773A1 (en) * 2001-08-24 2003-03-06 Pharmacia & Upjohn Company Substituted-aryl 7-aza¬2.2.1|bicycloheptanes for the treatment of disease
CA2457647A1 (en) * 2001-10-02 2003-04-10 Acadia Pharmaceuticals, Inc. Benzimidazolidinone derivatives as muscarinic agents
EP1480977A2 (en) 2002-02-15 2004-12-01 PHARMACIA &amp; UPJOHN COMPANY Substituted aryl compounds for treatment of disease
JP2005525357A (ja) * 2002-02-20 2005-08-25 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー α７ニコチン性アセチルコリン受容体活性を伴うアザ二環式化合物
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
SMT201800184T1 (it) 2009-05-20 2018-05-02 Inst Nat Sante Rech Med Antagonisti del recettore 5-ht3 della serotonina per uso nel trattamento di disordini da lesione vestibolare
ES2432618T3 (es) 2009-05-20 2013-12-04 Inserm (Institut National De La Santé Et De La Recherche Medicale) Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
US9692588B2 (en) 2015-07-07 2017-06-27 Samsung Electronics Co., Ltd. System and method for performing synchronization and interference rejection in super regenerative receiver (SRR)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068700A1 (en) * 1981-06-29 1983-01-05 Beecham Group Plc Azobicycloalkylbenzamides, process for their preparation and pharmaceutical compositions containing them
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
EP0099194A3 (en) * 1982-07-03 1984-04-11 Beecham Group Plc Novel benzamides
EP0102195A3 (en) * 1982-08-03 1984-04-11 Beecham Group Plc Substituted aza bicycloalkyl derivatives with dopamine antagonist activity
US4820715A (en) * 1984-06-28 1989-04-11 Bristol-Myers Company Anti-emetic quinuclidinyl benzamides
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides
US4870181A (en) * 1985-02-04 1989-09-26 A. H. Robins Company, Incorporated Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2])octan-3-yl)aminobenzamides
EP0220011A3 (en) * 1985-10-12 1990-01-03 Beecham Group Plc Use of azabicloalkylbenzamides in the treatment of gastrointestinal motility disorders, migraine, emesis, cluster headaches, trigeminal neuralgia and arrhythmia
US4717563A (en) * 1986-03-05 1988-01-05 A. H. Robins Company, Inc. 2-alkoxy-N-(1-azabicyclo(2.2.2)oct-3-yl) benzamides and thiobenzamides in a method for alleviating emesis caused by non-platinum anticancer drugs

Also Published As

Publication number Publication date
GB8718345D0 (en) 1987-09-09
CS272794B2 (en) 1991-02-12
PH25048A (en) 1991-01-28
NO168422B (no) 1991-11-11
SU1739849A3 (ru) 1992-06-07
DD282010A5 (de) 1990-08-29
AU629175B2 (en) 1992-10-01
IL87080A (en) 1992-09-06
JPS6450883A (en) 1989-02-27
NO168422C (no) 1992-02-19
HU200460B (en) 1990-06-28
NZ225657A (en) 1991-07-26
PL274010A1 (en) 1989-10-16
EP0302699A2 (en) 1989-02-08
FI883592A0 (fi) 1988-08-01
KR890003760A (ko) 1989-04-17
NO883428L (no) 1989-02-06
US4937236A (en) 1990-06-26
US4877780A (en) 1989-10-31
CN1031701A (zh) 1989-03-15
FI883592A7 (fi) 1989-02-04
EP0302699A3 (en) 1990-07-11
RO101203B (ro) 1992-01-10
AU2029388A (en) 1989-02-09
PT88175A (pt) 1989-06-30
HUT48246A (en) 1989-05-29
ZA885418B (en) 1989-04-26
PL154302B1 (en) 1991-07-31
MX12478A (es) 1993-12-01
NO883428D0 (no) 1988-08-02
DK429988D0 (da) 1988-08-02
IL87080A0 (en) 1988-12-30
DK429988A (da) 1989-04-05

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