CS251800B2 - Method of ergoline derivatives production - Google Patents

Method of ergoline derivatives production Download PDF

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Publication number
CS251800B2
CS251800B2 CS859255A CS925585A CS251800B2 CS 251800 B2 CS251800 B2 CS 251800B2 CS 859255 A CS859255 A CS 859255A CS 925585 A CS925585 A CS 925585A CS 251800 B2 CS251800 B2 CS 251800B2
Authority
CS
Czechoslovakia
Prior art keywords
alpha
beta
hydrogen
methyl
ergoline derivatives
Prior art date
Application number
CS859255A
Other languages
Czech (cs)
English (en)
Inventor
Gerhard Sauer
Helmut Biere
Gregor Haffer
Andreas Huth
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of CS251800B2 publication Critical patent/CS251800B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS859255A 1984-12-13 1985-12-13 Method of ergoline derivatives production CS251800B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843445784 DE3445784A1 (de) 1984-12-13 1984-12-13 Verfahren zur herstellung von ergolin-derivaten

Publications (1)

Publication Number Publication Date
CS251800B2 true CS251800B2 (en) 1987-08-13

Family

ID=6252855

Family Applications (1)

Application Number Title Priority Date Filing Date
CS859255A CS251800B2 (en) 1984-12-13 1985-12-13 Method of ergoline derivatives production

Country Status (9)

Country Link
US (1) US4968801A (fr)
EP (1) EP0190534B1 (fr)
JP (1) JPS61186381A (fr)
AT (1) ATE38990T1 (fr)
CA (1) CA1291120C (fr)
CS (1) CS251800B2 (fr)
DE (2) DE3445784A1 (fr)
DK (1) DK576585A (fr)
HU (1) HU193140B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3533675A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-brom-ergolinderivate
US4798834A (en) * 1987-08-31 1989-01-17 Eli Lilly And Company Optionally substituted (3β-9,10-didehydro-2,3-dihydro ergoline as serotonergic function enhancement
EP0628042B1 (fr) * 1992-12-24 2001-08-16 PHARMACIA & UPJOHN S.p.A. Derives d'ergolinie serotoninergiques
DE10066158B4 (de) * 2000-08-24 2007-08-09 Neurobiotec Gmbh Verwendung eines transdermalen therapeutischen Systems zur Behandlung des Restless-Legs-Syndroms
DE10053397A1 (de) * 2000-10-20 2002-05-02 Schering Ag Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen
US20070243240A9 (en) * 2000-08-24 2007-10-18 Fred Windt-Hanke Transdermal therapeutic system

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE204191C (fr) *
AT204191B (de) * 1954-09-27 1959-07-10 Lilly Co Eli Verfahren zur Herstellung von Lysergsäure und deren Homologen
US3954772A (en) * 1973-08-17 1976-05-04 Eli Lilly And Company Descarboxylysergic acid
EP0021206B1 (fr) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft Dérivés de l'(ergoline-yl)-N', N'-diéthylurée, leur préparation et médicaments les contenant
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
DE3205169A1 (de) * 1981-02-24 1982-10-14 Sandoz-Patent-GmbH, 7850 Lörrach Neue ergolinderivate, deren herstellung und deren pharmazeutische zusammensetzungen
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel

Also Published As

Publication number Publication date
HU193140B (en) 1987-08-28
ATE38990T1 (de) 1988-12-15
DK576585A (da) 1986-06-14
DE3445784A1 (de) 1986-06-26
EP0190534B1 (fr) 1988-11-30
DK576585D0 (da) 1985-12-12
JPS61186381A (ja) 1986-08-20
HUT39446A (en) 1986-09-29
CA1291120C (fr) 1991-10-22
EP0190534A1 (fr) 1986-08-13
US4968801A (en) 1990-11-06
DE3566544D1 (en) 1989-01-05

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