CS245766B2 - Preparation method of imidazoline derivatives - Google Patents

Preparation method of imidazoline derivatives Download PDF

Info

Publication number
CS245766B2
CS245766B2 CS82631A CS63182A CS245766B2 CS 245766 B2 CS245766 B2 CS 245766B2 CS 82631 A CS82631 A CS 82631A CS 63182 A CS63182 A CS 63182A CS 245766 B2 CS245766 B2 CS 245766B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
compound
alkyl
alkenyl
methyl
Prior art date
Application number
CS82631A
Other languages
Czech (cs)
English (en)
Inventor
Christopher B Chapleo
Peter L Myers
Original Assignee
Reckitt & Colmann Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt & Colmann Prod Ltd filed Critical Reckitt & Colmann Prod Ltd
Publication of CS245766B2 publication Critical patent/CS245766B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/201,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS82631A 1981-01-30 1982-01-29 Preparation method of imidazoline derivatives CS245766B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8102906 1981-01-30
GB8123277 1981-07-28

Publications (1)

Publication Number Publication Date
CS245766B2 true CS245766B2 (en) 1986-10-16

Family

ID=26278285

Family Applications (1)

Application Number Title Priority Date Filing Date
CS82631A CS245766B2 (en) 1981-01-30 1982-01-29 Preparation method of imidazoline derivatives

Country Status (22)

Country Link
US (1) US4397860A (el)
EP (1) EP0058006B1 (el)
AR (1) AR229957A1 (el)
AU (1) AU545344B2 (el)
CA (1) CA1176638A (el)
CS (1) CS245766B2 (el)
DE (1) DE3262919D1 (el)
DK (1) DK40482A (el)
ES (1) ES8302694A1 (el)
FI (1) FI67544C (el)
GB (1) GB2092139B (el)
GR (1) GR75168B (el)
HU (1) HU190983B (el)
IE (1) IE52310B1 (el)
IL (1) IL64880A (el)
NO (1) NO156865C (el)
NZ (1) NZ199469A (el)
PH (1) PH17747A (el)
PL (1) PL137716B1 (el)
PT (1) PT74354B (el)
SU (1) SU1197566A3 (el)
ZW (1) ZW1882A1 (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ203680A (en) * 1982-04-17 1985-08-16 Reckitt & Colmann Prod Ltd Imidazolines and pharmaceutical compositions
US4634714A (en) * 1983-12-01 1987-01-06 American Home Products Corporation Inhibition of prolactin release by a benzodioxinylimidazoline derivative
FR2698789B1 (fr) * 1992-12-07 1995-03-03 Pf Medicament Utilisation de l'idazoxan et ses dérivés pour la préparation d'un médicament destiné au traitement de la maladie de Parkinson et de son évolution.
FR2700113B1 (fr) * 1993-01-07 1995-03-24 Pf Medicament Utilisation de l'Idazoxan et ses dérivés pour la fabrication de médicaments destinés au traitement des maladies neurodégénératives et en particulier l'évolution de la maladie d'Alzheimer.
US6162455A (en) * 1997-01-22 2000-12-19 American Cyanamid Company Method for increasing lean meat, improving the lean meat to fat ratio and improving amino acid utilization in warm-blooded animals
FR2766824B1 (fr) * 1997-07-30 1999-09-10 Adir Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6650943B1 (en) 2000-04-07 2003-11-18 Advanced Bionics Corporation Fully implantable neurostimulator for cavernous nerve stimulation as a therapy for erectile dysfunction and other sexual dysfunction
US20050240229A1 (en) * 2001-04-26 2005-10-27 Whitehurst Tood K Methods and systems for stimulation as a therapy for erectile dysfunction
US6885895B1 (en) * 2001-04-26 2005-04-26 Advanced Bionics Corporation Methods and systems for electrical and/or drug stimulation as a therapy for erectile dysfunction
CN103030646B (zh) * 2011-09-29 2016-08-24 上海恒瑞医药有限公司 苯并二氧六环类衍生物、其制备方法及其在医药上的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2979511A (en) * 1959-03-25 1961-04-11 Olin Mathieson Certain 1, 4-benzodioxanyl imidazolines and corresponding pyrimidines and process
PH16249A (en) * 1980-02-04 1983-08-16 Reckitt & Colmann Prod Ltd Imidazoline derivatives,its pharmaceutical composition and method of use

Also Published As

Publication number Publication date
NZ199469A (en) 1984-03-16
PL235152A1 (en) 1983-07-18
EP0058006A1 (en) 1982-08-18
ES509131A0 (es) 1983-01-16
NO820258L (no) 1982-08-02
NO156865C (no) 1987-12-09
IE52310B1 (en) 1987-09-02
CA1176638A (en) 1984-10-23
AR229957A1 (es) 1984-01-31
ES8302694A1 (es) 1983-01-16
AU7992682A (en) 1982-08-05
ZW1882A1 (en) 1982-06-23
PT74354A (en) 1982-02-01
PL137716B1 (en) 1986-07-31
GB2092139A (en) 1982-08-11
PT74354B (en) 1983-07-04
US4397860A (en) 1983-08-09
FI820262L (fi) 1982-07-31
GR75168B (el) 1984-07-13
NO156865B (no) 1987-08-31
SU1197566A3 (ru) 1985-12-07
FI67544B (fi) 1984-12-31
DK40482A (da) 1982-07-31
IE820209L (en) 1982-07-30
IL64880A (en) 1985-04-30
DE3262919D1 (en) 1985-05-15
PH17747A (en) 1984-11-27
IL64880A0 (en) 1982-03-31
HU190983B (en) 1986-12-28
GB2092139B (en) 1984-10-31
FI67544C (fi) 1985-04-10
EP0058006B1 (en) 1985-04-10
AU545344B2 (en) 1985-07-11

Similar Documents

Publication Publication Date Title
RU2232154C2 (ru) Замещенные производные имидазола, способ введения фармацевтической композиции и способ лечения на основе этих соединений
US4818764A (en) Imidazoline derivative and method of treating depression therewith
HU222120B1 (hu) Helyettesített imidazolidin-2,4-dion-vegyületek, felhasználásuk gyógyászati hatóanyagokként és eljárás előállításukra
CS245766B2 (en) Preparation method of imidazoline derivatives
US5447943A (en) Novel benzopyran derivatives
CS229938B2 (en) Production method imidazoline derivative
CA1173044A (en) 2-(1,4-benzodioxan-2-ylalkyl)imidazoles useful as antidepressants
KR870001681B1 (ko) 히단토인 유도체의 제조방법
CA1185606A (en) Benzodioxane imidazoline compounds as antihypertensives
CA1245228A (en) Allylic amines
US5464859A (en) Benzospiroalkene derivatives
JPS59184162A (ja) キノリン誘導体、その製造法及び該化合物を含有する、5―ヒドロキシトリプタミン桔抗質として使用する医薬組成物
Bamgbose et al. SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL STUDIES OF 1–ETHYL–β–CARBOLINE
US4497818A (en) 2-(1,4-Benzodioxan-2-ylalkyl)imidazoles useful as antihypertensives and platelet aggregation inhibitors
KR840002005B1 (ko) 피페라진 유도체의 제조방법
JPS5858352B2 (ja) 置換2−フエニルアミノイミダゾリン−(2)誘導体及びその製造法並びにその薬学的組成物
IE52074B1 (en) 2-(1,4-benzodioxan-2-ylalkyl)imidazoles,their preparation and pharmaceutical compositions containing them