CS218348B1 - Method of desalting the synthetic pepside - Google Patents
Method of desalting the synthetic pepside Download PDFInfo
- Publication number
- CS218348B1 CS218348B1 CS81862A CS86281A CS218348B1 CS 218348 B1 CS218348 B1 CS 218348B1 CS 81862 A CS81862 A CS 81862A CS 86281 A CS86281 A CS 86281A CS 218348 B1 CS218348 B1 CS 218348B1
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- ohp
- coal
- solvent
- thp
- water
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 11
- 238000011033 desalting Methods 0.000 title claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 22
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 21
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 9
- 150000003839 salts Chemical class 0.000 claims description 8
- 239000007864 aqueous solution Substances 0.000 claims description 6
- 239000003960 organic solvent Substances 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 3
- 125000001931 aliphatic group Chemical group 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 239000000741 silica gel Substances 0.000 claims description 3
- 229910002027 silica gel Inorganic materials 0.000 claims description 3
- 230000029936 alkylation Effects 0.000 claims description 2
- 238000005804 alkylation reaction Methods 0.000 claims description 2
- 125000004432 carbon atom Chemical group C* 0.000 claims description 2
- 239000003245 coal Substances 0.000 abstract 8
- 239000007788 liquid Substances 0.000 abstract 5
- 239000002904 solvent Substances 0.000 abstract 5
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 4
- 239000011707 mineral Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000000446 fuel Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000004064 recycling Methods 0.000 abstract 1
- 238000007614 solvation Methods 0.000 abstract 1
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 abstract 1
- 229910052721 tungsten Inorganic materials 0.000 abstract 1
- 239000010937 tungsten Substances 0.000 abstract 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 18
- 239000000243 solution Substances 0.000 description 8
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- -1 octadecyltrichlorosilane alkylated silica gel Chemical class 0.000 description 6
- 108010000437 Deamino Arginine Vasopressin Proteins 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 238000010612 desalination reaction Methods 0.000 description 3
- NFLWUMRGJYTJIN-PNIOQBSNSA-N desmopressin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(N)=O)=O)CCC(=O)N)C1=CC=CC=C1 NFLWUMRGJYTJIN-PNIOQBSNSA-N 0.000 description 3
- 238000010828 elution Methods 0.000 description 3
- 238000002211 ultraviolet spectrum Methods 0.000 description 3
- KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 239000000539 dimer Substances 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000004128 high performance liquid chromatography Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000008363 phosphate buffer Substances 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- JGLCYGDOFQBJND-AVGNSLFASA-N (2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-amino-4-sulfanylbutanoyl]pyrrolidine-2-carboxamide Chemical compound N[C@@H](CCS)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N JGLCYGDOFQBJND-AVGNSLFASA-N 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 102400000050 Oxytocin Human genes 0.000 description 1
- XNOPRXBHLZRZKH-UHFFFAOYSA-N Oxytocin Natural products N1C(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C(C)CC)NC(=O)C1CC1=CC=C(O)C=C1 XNOPRXBHLZRZKH-UHFFFAOYSA-N 0.000 description 1
- 101800000989 Oxytocin Proteins 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000002523 gelfiltration Methods 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000004811 liquid chromatography Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- XNOPRXBHLZRZKH-DSZYJQQASA-N oxytocin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 XNOPRXBHLZRZKH-DSZYJQQASA-N 0.000 description 1
- 229960001723 oxytocin Drugs 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000010647 peptide synthesis reaction Methods 0.000 description 1
- 239000000276 potassium ferrocyanide Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- XOGGUFAVLNCTRS-UHFFFAOYSA-N tetrapotassium;iron(2+);hexacyanide Chemical compound [K+].[K+].[K+].[K+].[Fe+2].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] XOGGUFAVLNCTRS-UHFFFAOYSA-N 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10G—CRACKING HYDROCARBON OILS; PRODUCTION OF LIQUID HYDROCARBON MIXTURES, e.g. BY DESTRUCTIVE HYDROGENATION, OLIGOMERISATION, POLYMERISATION; RECOVERY OF HYDROCARBON OILS FROM OIL-SHALE, OIL-SAND, OR GASES; REFINING MIXTURES MAINLY CONSISTING OF HYDROCARBONS; REFORMING OF NAPHTHA; MINERAL WAXES
- C10G45/00—Refining of hydrocarbon oils using hydrogen or hydrogen-generating compounds
- C10G45/44—Hydrogenation of the aromatic hydrocarbons
- C10G45/46—Hydrogenation of the aromatic hydrocarbons characterised by the catalyst used
- C10G45/48—Hydrogenation of the aromatic hydrocarbons characterised by the catalyst used containing nickel or cobalt metal, or compounds thereof
- C10G45/50—Hydrogenation of the aromatic hydrocarbons characterised by the catalyst used containing nickel or cobalt metal, or compounds thereof in combination with chromium, molybdenum or tungsten metal, or compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10G—CRACKING HYDROCARBON OILS; PRODUCTION OF LIQUID HYDROCARBON MIXTURES, e.g. BY DESTRUCTIVE HYDROGENATION, OLIGOMERISATION, POLYMERISATION; RECOVERY OF HYDROCARBON OILS FROM OIL-SHALE, OIL-SAND, OR GASES; REFINING MIXTURES MAINLY CONSISTING OF HYDROCARBONS; REFORMING OF NAPHTHA; MINERAL WAXES
- C10G1/00—Production of liquid hydrocarbon mixtures from oil-shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal
- C10G1/04—Production of liquid hydrocarbon mixtures from oil-shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal by extraction
- C10G1/042—Production of liquid hydrocarbon mixtures from oil-shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal by extraction by the use of hydrogen-donor solvents
-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10G—CRACKING HYDROCARBON OILS; PRODUCTION OF LIQUID HYDROCARBON MIXTURES, e.g. BY DESTRUCTIVE HYDROGENATION, OLIGOMERISATION, POLYMERISATION; RECOVERY OF HYDROCARBON OILS FROM OIL-SHALE, OIL-SAND, OR GASES; REFINING MIXTURES MAINLY CONSISTING OF HYDROCARBONS; REFORMING OF NAPHTHA; MINERAL WAXES
- C10G1/00—Production of liquid hydrocarbon mixtures from oil-shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal
- C10G1/06—Production of liquid hydrocarbon mixtures from oil-shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal by destructive hydrogenation
- C10G1/065—Production of liquid hydrocarbon mixtures from oil-shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal by destructive hydrogenation in the presence of a solvent
-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10G—CRACKING HYDROCARBON OILS; PRODUCTION OF LIQUID HYDROCARBON MIXTURES, e.g. BY DESTRUCTIVE HYDROGENATION, OLIGOMERISATION, POLYMERISATION; RECOVERY OF HYDROCARBON OILS FROM OIL-SHALE, OIL-SAND, OR GASES; REFINING MIXTURES MAINLY CONSISTING OF HYDROCARBONS; REFORMING OF NAPHTHA; MINERAL WAXES
- C10G45/00—Refining of hydrocarbon oils using hydrogen or hydrogen-generating compounds
- C10G45/44—Hydrogenation of the aromatic hydrocarbons
Landscapes
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
- Peptides Or Proteins (AREA)
- Solid Fuels And Fuel-Associated Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/118,860 US4322284A (en) | 1980-02-05 | 1980-02-05 | Solvent refining of coal using octahydrophenanthrene-enriched solvent and coal minerals recycle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS218348B1 true CS218348B1 (en) | 1983-02-25 |
Family
ID=22381184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS81862A CS218348B1 (en) | 1980-02-05 | 1981-02-04 | Method of desalting the synthetic pepside |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4322284A (es) |
| EP (1) | EP0033621A1 (es) |
| JP (1) | JPS57500073A (es) |
| BR (1) | BR8105664A (es) |
| CS (1) | CS218348B1 (es) |
| DD (1) | DD156920A5 (es) |
| ES (1) | ES8202580A1 (es) |
| PL (1) | PL229511A1 (es) |
| WO (1) | WO1981002305A1 (es) |
| ZA (1) | ZA81487B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4495055A (en) * | 1982-04-05 | 1985-01-22 | Hri, Inc. | Coal catalytic hydrogenation process using direct coal slurry feed to reactor with controlled mixing conditions |
| US4741806A (en) * | 1983-03-16 | 1988-05-03 | Phillips Petroleum Company | Solvent Extractor |
| JPH0730340B2 (ja) * | 1983-05-16 | 1995-04-05 | 三菱化学株式会社 | 石炭の油留分への転化方法 |
| US4511460A (en) * | 1984-03-21 | 1985-04-16 | International Coal Refining Company | Minimizing corrosion in coal liquid distillation |
| US5047300A (en) * | 1989-06-14 | 1991-09-10 | Bolder Battery, Inc. | Ultra-thin plate electrochemical cell |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3505203A (en) * | 1967-06-26 | 1970-04-07 | Universal Oil Prod Co | Solvent extraction method |
| US3503864A (en) * | 1967-12-29 | 1970-03-31 | Universal Oil Prod Co | Coal liquefaction method |
| US3488278A (en) * | 1968-01-25 | 1970-01-06 | Universal Oil Prod Co | Process for treating coal |
| US3726785A (en) * | 1971-03-03 | 1973-04-10 | Exxon Research Engineering Co | Coal liquefaction using high and low boiling solvents |
| US3867275A (en) * | 1973-04-09 | 1975-02-18 | Universal Oil Prod Co | Coal liquefaction process |
| US3884794A (en) * | 1974-03-04 | 1975-05-20 | Us Interior | Solvent refined coal process including recycle of coal minerals |
| US4048054A (en) * | 1976-07-23 | 1977-09-13 | Exxon Research And Engineering Company | Liquefaction of coal |
| US4022680A (en) * | 1975-12-17 | 1977-05-10 | Exxon Research And Engineering Company | Hydrogen donor solvent coal liquefaction process |
| US4018663A (en) * | 1976-01-05 | 1977-04-19 | The United States Of America As Represented By The United States Energy Research And Development Administration | Coal liquefaction process |
| US4051012A (en) * | 1976-05-17 | 1977-09-27 | Exxon Research & Engineering Co. | Coal liquefaction process |
| US4045328A (en) * | 1976-07-23 | 1977-08-30 | Exxon Research And Engineering Company | Production of hydrogenated coal liquids |
| US4123347A (en) * | 1976-12-22 | 1978-10-31 | Exxon Research & Engineering Co. | Coal liquefaction process |
| US4190518A (en) * | 1977-12-29 | 1980-02-26 | Gulf Research And Development Company | Solvent refined coal process |
| DE2808421A1 (de) * | 1978-02-27 | 1979-08-30 | Exxon Research Engineering Co | Verfahren zur verfluessigung von kohle und kohlehaltigen feststoffen |
| US4252633A (en) * | 1978-08-21 | 1981-02-24 | Exxon Research & Engineering Co. | Coal liquefaction process |
| US4222848A (en) * | 1978-12-15 | 1980-09-16 | Gulf Oil Corporation | Coal liquefaction process employing extraneous minerals |
| US4255248A (en) * | 1979-09-07 | 1981-03-10 | Chevron Research Company | Two-stage coal liquefaction process with process-derived solvent having a low heptane-insolubiles content |
-
1980
- 1980-02-05 US US06/118,860 patent/US4322284A/en not_active Expired - Lifetime
-
1981
- 1981-01-02 WO PCT/US1981/000004 patent/WO1981002305A1/en not_active Ceased
- 1981-01-02 JP JP56500935A patent/JPS57500073A/ja active Pending
- 1981-01-02 BR BR8105664A patent/BR8105664A/pt unknown
- 1981-01-23 ZA ZA00810487A patent/ZA81487B/xx unknown
- 1981-01-26 EP EP81300329A patent/EP0033621A1/en not_active Withdrawn
- 1981-02-04 PL PL22951181A patent/PL229511A1/xx unknown
- 1981-02-04 ES ES499095A patent/ES8202580A1/es not_active Expired
- 1981-02-04 CS CS81862A patent/CS218348B1/cs unknown
- 1981-02-05 DD DD81227455A patent/DD156920A5/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4322284A (en) | 1982-03-30 |
| BR8105664A (pt) | 1981-12-15 |
| WO1981002305A1 (en) | 1981-08-20 |
| JPS57500073A (es) | 1982-01-14 |
| ES499095A0 (es) | 1982-02-01 |
| DD156920A5 (de) | 1982-09-29 |
| EP0033621A1 (en) | 1981-08-12 |
| PL229511A1 (es) | 1981-10-16 |
| ES8202580A1 (es) | 1982-02-01 |
| ZA81487B (en) | 1982-02-24 |
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