CS215055B2 - Method of making the substituted 2-aminopyrazines - Google Patents

Method of making the substituted 2-aminopyrazines Download PDF

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Publication number
CS215055B2
CS215055B2 CS802293A CS229380A CS215055B2 CS 215055 B2 CS215055 B2 CS 215055B2 CS 802293 A CS802293 A CS 802293A CS 229380 A CS229380 A CS 229380A CS 215055 B2 CS215055 B2 CS 215055B2
Authority
CS
Czechoslovakia
Prior art keywords
substituted
reaction
mol
acid
mixture
Prior art date
Application number
CS802293A
Other languages
Czech (cs)
English (en)
Inventor
Charles J Barnett
Thomas L Emmick
Richard Ch Hoying
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS215055B2 publication Critical patent/CS215055B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/35—Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • C07C33/20—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part monocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12C—BEER; PREPARATION OF BEER BY FERMENTATION; PREPARATION OF MALT FOR MAKING BEER; PREPARATION OF HOPS FOR MAKING BEER
    • C12C11/00—Fermentation processes for beer
    • C12C11/02—Pitching yeast

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CS802293A 1979-04-06 1980-04-02 Method of making the substituted 2-aminopyrazines CS215055B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/027,630 US4211870A (en) 1979-04-06 1979-04-06 Preparation of substituted 2-aminopyrazines

Publications (1)

Publication Number Publication Date
CS215055B2 true CS215055B2 (en) 1982-07-30

Family

ID=21838837

Family Applications (1)

Application Number Title Priority Date Filing Date
CS802293A CS215055B2 (en) 1979-04-06 1980-04-02 Method of making the substituted 2-aminopyrazines

Country Status (25)

Country Link
US (1) US4211870A (fr)
EP (1) EP0018144A1 (fr)
JP (1) JPS55141473A (fr)
KR (1) KR830002731A (fr)
AU (1) AU5710280A (fr)
BE (1) BE882608A (fr)
BR (1) BR8002079A (fr)
CA (1) CA1157860A (fr)
CS (1) CS215055B2 (fr)
DD (1) DD150057A5 (fr)
DK (1) DK144280A (fr)
ES (1) ES8105303A1 (fr)
FI (1) FI801056A (fr)
FR (1) FR2453159A1 (fr)
GB (1) GB2046751A (fr)
GR (1) GR68096B (fr)
IL (1) IL59761A0 (fr)
IT (1) IT1147345B (fr)
LU (1) LU82342A1 (fr)
NZ (1) NZ193345A (fr)
PL (1) PL223264A1 (fr)
PT (1) PT71056A (fr)
RO (1) RO79384A (fr)
SU (1) SU932989A3 (fr)
ZA (1) ZA802005B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2209465C (fr) * 1996-07-11 2008-04-29 Lonza Ag Methode de preparation de 3-alcoxy-5-alkylpyrazin-2-amines
KR20030031886A (ko) * 2000-02-16 2003-04-23 뉴로젠 코포레이션 치환된 아릴피라진
CA2496197A1 (fr) * 2002-08-20 2004-03-04 Neurogen Corporation 2-arylpyrazines substituees en 5 comme modulateurs sur les recepteurs crf

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794329A (fr) * 1972-01-20 1973-07-19 Pechiney Ugine Kuhlmann Derives d'aza-2 butadienes-1,3 et procede pour leur preparation
EG11837A (en) * 1974-09-19 1977-12-31 Lilly Co Eli Novel 1-(substituted benzoyl)-3-(substituted pyrazinyl ureas used as insecticides
US4160834A (en) * 1977-03-09 1979-07-10 Eli Lilly And Company 1-(Substituted benzoyl)-3-(substituted pyrazinyl)ureas

Also Published As

Publication number Publication date
LU82342A1 (fr) 1980-07-02
IT8021231A0 (it) 1980-04-04
ES490287A0 (es) 1981-05-16
BR8002079A (pt) 1980-11-25
FR2453159A1 (fr) 1980-10-31
ES8105303A1 (es) 1981-05-16
ZA802005B (en) 1981-11-25
GB2046751A (en) 1980-11-19
SU932989A3 (ru) 1982-05-30
NZ193345A (en) 1982-11-23
IL59761A0 (en) 1980-06-30
PT71056A (en) 1980-05-01
GR68096B (fr) 1981-10-30
US4211870A (en) 1980-07-08
KR830002731A (ko) 1983-05-30
BE882608A (fr) 1980-10-03
DD150057A5 (de) 1981-08-12
CA1157860A (fr) 1983-11-29
AU5710280A (en) 1980-10-09
EP0018144A1 (fr) 1980-10-29
IT1147345B (it) 1986-11-19
RO79384A (fr) 1982-06-25
FI801056A (fi) 1980-10-07
DK144280A (da) 1980-10-07
PL223264A1 (fr) 1981-01-30
JPS55141473A (en) 1980-11-05

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