CS208494B2 - Method of making the alcylesters of the 4-halogen-3-oxoandrosta-1,4-dien-17 beta-cyrboxyl acid - Google Patents

Method of making the alcylesters of the 4-halogen-3-oxoandrosta-1,4-dien-17 beta-cyrboxyl acid Download PDF

Info

Publication number
CS208494B2
CS208494B2 CS792304A CS230479A CS208494B2 CS 208494 B2 CS208494 B2 CS 208494B2 CS 792304 A CS792304 A CS 792304A CS 230479 A CS230479 A CS 230479A CS 208494 B2 CS208494 B2 CS 208494B2
Authority
CS
Czechoslovakia
Prior art keywords
alpha
beta
methyl
acid
formula
Prior art date
Application number
CS792304A
Other languages
Czech (cs)
English (en)
Inventor
Francisco S Alvarez
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of CS208494B2 publication Critical patent/CS208494B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS792304A 1978-04-05 1979-04-04 Method of making the alcylesters of the 4-halogen-3-oxoandrosta-1,4-dien-17 beta-cyrboxyl acid CS208494B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89364378A 1978-04-05 1978-04-05

Publications (1)

Publication Number Publication Date
CS208494B2 true CS208494B2 (en) 1981-09-15

Family

ID=25401852

Family Applications (2)

Application Number Title Priority Date Filing Date
CS792304A CS208494B2 (en) 1978-04-05 1979-04-04 Method of making the alcylesters of the 4-halogen-3-oxoandrosta-1,4-dien-17 beta-cyrboxyl acid
CS797019A CS208495B2 (en) 1978-04-05 1979-04-04 Method of making the alcyesters of the 4-halogen-3-oxo-androsta-1,4-dien beta-carboxyle acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS797019A CS208495B2 (en) 1978-04-05 1979-04-04 Method of making the alcyesters of the 4-halogen-3-oxo-androsta-1,4-dien beta-carboxyle acid

Country Status (14)

Country Link
EP (1) EP0004772A3 (es)
JP (1) JPS54141757A (es)
AU (1) AU4575479A (es)
CS (2) CS208494B2 (es)
DK (1) DK136779A (es)
ES (1) ES479270A1 (es)
FI (1) FI791087A (es)
GR (1) GR65613B (es)
IL (1) IL56990A0 (es)
IT (1) IT7967677A0 (es)
NO (1) NO791144L (es)
PL (1) PL214674A1 (es)
PT (1) PT69411A (es)
ZA (1) ZA791636B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04506066A (ja) * 1989-06-16 1992-10-22 ジ・アップジョン・カンパニー 脈管形成を抑制するためのスラミン・タイプの化合物および脈管形成抑止ステロイド類
US5646136A (en) * 1994-01-04 1997-07-08 Duke University Methods of inhibiting angiogenesis and tumor growth, and treating ophthalmologic conditions with angiostatic and therapeutic steroids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636010A (en) * 1968-12-23 1972-01-18 Ciba Geigy Corp Esters of steroid-17-carboxylic acids
CH628355A5 (de) * 1976-02-24 1982-02-26 Ciba Geigy Ag Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.

Also Published As

Publication number Publication date
JPS54141757A (en) 1979-11-05
EP0004772A2 (en) 1979-10-17
ES479270A1 (es) 1980-01-16
GR65613B (en) 1980-10-14
PT69411A (en) 1979-04-01
AU4575479A (en) 1979-10-11
FI791087A (fi) 1979-10-06
ZA791636B (en) 1980-11-26
IT7967677A0 (it) 1979-03-30
IL56990A0 (en) 1979-07-25
DK136779A (da) 1979-10-06
PL214674A1 (es) 1980-08-11
CS208495B2 (en) 1981-09-15
NO791144L (no) 1979-10-08
EP0004772A3 (en) 1979-10-31

Similar Documents

Publication Publication Date Title
CS203956B2 (en) Method of producing derivatives of 3-oxoandrostene /or androstadiene/ thiocarboxylic acid
EP0004773B1 (en) 17-beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes, their pharmaceutical use and processes for their preparation
US4187301A (en) 17 Beta-thiocarboxylic acid esters of 6 alpha, 6 beta-difluoro-3-oxoandrost-4-enes
US4076708A (en) Process for the preparation of 7α-halogeno-3-oxo-4-dehydro steroids and novel 7α-halogeno derivatives produced thereby
JPS6139959B2 (es)
FI80888C (fi) Foerfarande foer framstaellning av terapeutiskt verkande steroida karboxylsyraestrar.
US4261984A (en) 17β-thiocarboxylic acid esters of 3-oxo-4-halo-16β-methylandrost-4-enes
US4226862A (en) Steroids and process for preparing the same
CH533094A (de) Verfahren zur Herstellung neuer Steroide
EP0004765B1 (en) Corticosteroid anti-inflammatory agents, their use and methods for their preparation
CS266580B2 (en) Method of androstane-17 beta-carboxyl acid's new esters production
DE3102397A1 (de) 17(alpha)-acyloxy-5(beta)-corticoide und 17(alpha)-acyloxy-5(alpha)-corticoide
CS208494B2 (en) Method of making the alcylesters of the 4-halogen-3-oxoandrosta-1,4-dien-17 beta-cyrboxyl acid
GB1563638A (en) 21-halogenopregnane compounds
US4261986A (en) 4-Halo etianic acids and derivatives thereof
CA1073449A (en) 21-acetals and mixed acetals of steroidal 21-aldehydes, intermediates and methods of preparation
US4278669A (en) 3-Oxo-4-halo-16β-methylandrost-4-ene 17β-carboxylic acids and esters
US4273770A (en) 4-Halo steroids
US4272446A (en) Steroids and process for preparing the same
HU182775B (en) Process for preparing new 3-chloro-pregnane derivatives
CS209915B2 (en) Method of making the 4-halogenpregna-1,4-dien-3,20-dions
US3931167A (en) Process for the manufacture of 3-keto-6-azido-4,6-bis-dehydro-steroids and intermediates useful therein
NO864979L (no) Androstan-17 beta-karboksylsyreforbindelser.
JPS604198B2 (ja) ３，２０―ジオキソ―７α―ハロ―４―プレグネン類または―１．４―プレグナジエン類、およびその製造方法ならびに該化合物を含有する抗炎症剤
HU176255B (en) Process for producing new d-homo-steroides