CS208164B2 - Method of making the d-2-halogene-6-methyl-8-kyan/carboxamido/methylergolines - Google Patents

Method of making the d-2-halogene-6-methyl-8-kyan/carboxamido/methylergolines Download PDF

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Publication number
CS208164B2
CS208164B2 CS735239A CS523973A CS208164B2 CS 208164 B2 CS208164 B2 CS 208164B2 CS 735239 A CS735239 A CS 735239A CS 523973 A CS523973 A CS 523973A CS 208164 B2 CS208164 B2 CS 208164B2
Authority
CS
Czechoslovakia
Prior art keywords
methyl
ergoline
formula
compounds
compound
Prior art date
Application number
CS735239A
Other languages
Czech (cs)
English (en)
Inventor
James A Clemens
Edmund C Kornfeld
Nicholas J Bach
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Priority to CS776672A priority Critical patent/CS208165B2/cs
Publication of CS208164B2 publication Critical patent/CS208164B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS735239A 1972-07-21 1973-07-20 Method of making the d-2-halogene-6-methyl-8-kyan/carboxamido/methylergolines CS208164B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS776672A CS208165B2 (cs) 1972-07-21 1977-10-13 Způsob výroby D-6-methyl-8-mesyIoxymethylergoIinu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27390272A 1972-07-21 1972-07-21

Publications (1)

Publication Number Publication Date
CS208164B2 true CS208164B2 (en) 1981-08-31

Family

ID=23045910

Family Applications (1)

Application Number Title Priority Date Filing Date
CS735239A CS208164B2 (en) 1972-07-21 1973-07-20 Method of making the d-2-halogene-6-methyl-8-kyan/carboxamido/methylergolines

Country Status (24)

Country Link
JP (2) JPS576431B2 (is)
AR (3) AR206772A1 (is)
AT (1) AT331425B (is)
BE (1) BE802531A (is)
BG (3) BG22400A3 (is)
CA (1) CA1006159A (is)
CH (5) CH580625A5 (is)
CS (1) CS208164B2 (is)
DD (1) DD107690A5 (is)
DE (2) DE2335750C3 (is)
DK (1) DK140986B (is)
ES (5) ES417078A1 (is)
FR (1) FR2193606B1 (is)
GB (1) GB1423065A (is)
HU (1) HU167274B (is)
IE (1) IE37936B1 (is)
IL (3) IL42730A (is)
NL (1) NL7309969A (is)
PH (1) PH11229A (is)
RO (2) RO71305A (is)
SE (3) SE393111B (is)
SU (3) SU645581A3 (is)
YU (1) YU36953B (is)
ZA (1) ZA734627B (is)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517971A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 8alpha-substituted ergoline i derivatives
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
DE3587860D1 (de) * 1984-04-09 1994-07-28 Schering Ag 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
HU196598B (en) * 1986-04-25 1988-12-28 Richter Gedeon Vegyeszet Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
JPH0596382U (ja) * 1992-05-28 1993-12-27 イビデン株式会社 ドアユニット

Also Published As

Publication number Publication date
SU645581A3 (ru) 1979-01-30
IL42730A (en) 1976-06-30
NL7309969A (is) 1974-01-23
IL42730A0 (en) 1973-10-25
SU584780A3 (ru) 1977-12-15
GB1423065A (en) 1976-01-28
ES442885A1 (es) 1977-04-16
JPS5813541B2 (ja) 1983-03-14
JPS5781487A (en) 1982-05-21
CH580625A5 (is) 1976-10-15
SE393111B (sv) 1977-05-02
DD107690A5 (is) 1974-08-12
DK140986C (is) 1980-07-21
BE802531A (fr) 1974-01-21
SE7611467L (sv) 1976-10-15
BG21410A3 (bg) 1976-05-20
FR2193606B1 (is) 1977-07-15
AR206887A1 (es) 1976-08-31
AT331425B (de) 1976-08-25
CH580626A5 (is) 1976-10-15
RO71305A (ro) 1982-03-24
SU575029A3 (ru) 1977-09-30
ATA643473A (de) 1975-11-15
IE37936L (en) 1974-01-21
ZA734627B (en) 1974-06-26
IL48288A0 (en) 1975-12-31
DE2365974A1 (de) 1977-03-24
YU194573A (en) 1982-06-18
HU167274B (is) 1975-09-27
ES417078A1 (es) 1976-05-01
ES446789A1 (es) 1977-06-01
CH578563A5 (is) 1976-08-13
CH581135A5 (is) 1976-10-29
BG22400A3 (bg) 1977-02-20
AR206772A1 (es) 1976-08-23
FR2193606A1 (is) 1974-02-22
AR210072A1 (es) 1977-06-30
IE37936B1 (en) 1977-11-23
BG21411A3 (is) 1976-05-20
IL48288A (en) 1976-06-30
JPS4985099A (is) 1974-08-15
CH578564A5 (is) 1976-08-13
PH11229A (en) 1977-10-28
ES442887A1 (es) 1977-05-16
SE410459B (sv) 1979-10-15
JPS576431B2 (is) 1982-02-04
ES442886A1 (es) 1977-04-16
AU5792673A (en) 1975-01-16
RO63792A (fr) 1978-12-15
YU36953B (en) 1984-08-31
DE2335750C3 (de) 1978-10-19
DE2335750B2 (de) 1978-02-23
DE2335750A1 (de) 1974-02-14
CA1006159A (en) 1977-03-01
DK140986B (da) 1979-12-17
SE410603B (sv) 1979-10-22
SE7611466L (sv) 1976-10-15

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