CS207387A2 - Method of phenoxyalkylcarboxyl acid's derivatives production - Google Patents
Method of phenoxyalkylcarboxyl acid's derivatives productionInfo
- Publication number
- CS207387A2 CS207387A2 CS872073A CS207387A CS207387A2 CS 207387 A2 CS207387 A2 CS 207387A2 CS 872073 A CS872073 A CS 872073A CS 207387 A CS207387 A CS 207387A CS 207387 A2 CS207387 A2 CS 207387A2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- group
- alkyl
- trifluoromethyl
- cyano
- alkoxy
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000000055 hyoplipidemic effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- -1 nitro, amino Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/02—Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Professional, Industrial, Or Sporting Protective Garments (AREA)
- Detergent Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863610643 DE3610643A1 (de) | 1986-03-29 | 1986-03-29 | Neue phenoxyalkylcarbonsaeure-derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS207387A2 true CS207387A2 (en) | 1990-02-12 |
| CS271469B2 CS271469B2 (en) | 1990-10-12 |
Family
ID=6297529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS872073A CS271469B2 (en) | 1986-03-29 | 1987-03-26 | Method of phenoxyalkylcarboxyl acid's derivatives production |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0239907B1 (cs) |
| JP (1) | JPS62238259A (cs) |
| AT (1) | ATE67483T1 (cs) |
| AU (1) | AU582043B2 (cs) |
| CS (1) | CS271469B2 (cs) |
| DD (1) | DD263287A5 (cs) |
| DE (2) | DE3610643A1 (cs) |
| DK (1) | DK155387A (cs) |
| ES (1) | ES2037676T3 (cs) |
| FI (1) | FI871360A7 (cs) |
| GR (1) | GR3003100T3 (cs) |
| HU (1) | HU197879B (cs) |
| IL (1) | IL82039A0 (cs) |
| PT (1) | PT84572B (cs) |
| ZA (1) | ZA872254B (cs) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8528398D0 (en) * | 1985-11-19 | 1985-12-24 | Glaxo Group Ltd | Chemical compounds |
| JPS62277347A (ja) * | 1986-02-25 | 1987-12-02 | Microbial Chem Res Found | 新規生理活性物質ア−ブスタチン類縁化合物 |
| IL83230A (en) * | 1986-08-06 | 1992-06-21 | Tanabe Seiyaku Co | Phenoxyacetic acid derivatives,their preparation and pharmaceutical compositions containing them |
| AT396235B (de) * | 1987-02-06 | 1993-07-26 | Tanabe Seiyaku Co | Phenoxyessigsaeurederivate und ihre herstellung |
| GB8708233D0 (en) * | 1987-04-07 | 1987-05-13 | Smith Kline French Lab | Pharmaceutically active compounds |
| JPH068274B2 (ja) * | 1988-01-19 | 1994-02-02 | 田辺製薬株式会社 | フェノキシ酢酸誘導体 |
| JPH068275B2 (ja) * | 1988-02-04 | 1994-02-02 | 田辺製薬株式会社 | フェノキシ酢酸誘導体 |
| EP0325245B1 (en) * | 1988-01-19 | 1993-10-20 | Tanabe Seiyaku Co., Ltd. | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use |
| US5173500A (en) * | 1988-08-31 | 1992-12-22 | Boehringer Mannheim Gmbh | Pharmaceutical compositions and methods of sulphonamides containing a tetrazolyl radical |
| DE3829431A1 (de) * | 1988-08-31 | 1990-03-01 | Boehringer Mannheim Gmbh | Sulfonamide mit tetrazolylrest, verfahren zur ihrer herstellung sowie arzneimittel |
| DE3829455A1 (de) * | 1988-08-31 | 1990-03-15 | Boehringer Mannheim Gmbh | Sulfonamidoalkyl-cyclohexan-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel |
| US5280043A (en) * | 1988-10-10 | 1994-01-18 | Smith Kline & French Laboratories Ltd. | Sulphonamido containing phenylalkanoic acids as thromboxane A2 antagonists |
| US5256812A (en) * | 1989-01-31 | 1993-10-26 | Hoffmann-La Roche Inc. | Carboxamides and sulfonamides |
| US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
| DE3942923A1 (de) * | 1989-12-23 | 1991-06-27 | Boehringer Mannheim Gmbh | Neue phenoxyalkylcarbonsaeure-amide, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
| JPH05125038A (ja) * | 1991-03-07 | 1993-05-21 | Tanabe Seiyaku Co Ltd | フエノキシアルカン酸誘導体及びその製法 |
| US5360909A (en) * | 1992-03-23 | 1994-11-01 | Terumo Kabushiki Kaisha | Phenoxyacetic acid compounds and medical preparations containing them |
| IL110172A (en) * | 1993-07-22 | 2001-10-31 | Lilly Co Eli | Bicyclic compounds and pharmaceutical compositions containing them |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2809377A1 (de) * | 1978-03-04 | 1979-09-13 | Boehringer Mannheim Gmbh | Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| GB8528398D0 (en) * | 1985-11-19 | 1985-12-24 | Glaxo Group Ltd | Chemical compounds |
-
1986
- 1986-03-29 DE DE19863610643 patent/DE3610643A1/de not_active Withdrawn
-
1987
- 1987-03-24 EP EP87104281A patent/EP0239907B1/de not_active Expired - Lifetime
- 1987-03-24 AT AT87104281T patent/ATE67483T1/de not_active IP Right Cessation
- 1987-03-24 DE DE8787104281T patent/DE3773026D1/de not_active Expired - Lifetime
- 1987-03-24 ES ES198787104281T patent/ES2037676T3/es not_active Expired - Lifetime
- 1987-03-25 DD DD87301115A patent/DD263287A5/de not_active IP Right Cessation
- 1987-03-26 PT PT84572A patent/PT84572B/pt not_active IP Right Cessation
- 1987-03-26 CS CS872073A patent/CS271469B2/cs unknown
- 1987-03-26 DK DK155387A patent/DK155387A/da not_active Application Discontinuation
- 1987-03-27 HU HU871347A patent/HU197879B/hu not_active IP Right Cessation
- 1987-03-27 JP JP62071957A patent/JPS62238259A/ja active Pending
- 1987-03-27 AU AU70723/87A patent/AU582043B2/en not_active Ceased
- 1987-03-27 FI FI871360A patent/FI871360A7/fi not_active Application Discontinuation
- 1987-03-27 ZA ZA872254A patent/ZA872254B/xx unknown
- 1987-03-29 IL IL82039A patent/IL82039A0/xx unknown
-
1991
- 1991-11-11 GR GR91401329T patent/GR3003100T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT43559A (en) | 1987-11-30 |
| PT84572B (pt) | 1989-11-30 |
| FI871360A0 (fi) | 1987-03-27 |
| FI871360A7 (fi) | 1987-09-30 |
| DE3610643A1 (de) | 1987-10-01 |
| EP0239907A1 (de) | 1987-10-07 |
| HU197879B (en) | 1989-06-28 |
| PT84572A (de) | 1987-04-01 |
| IL82039A0 (en) | 1987-10-20 |
| JPS62238259A (ja) | 1987-10-19 |
| GR3003100T3 (en) | 1993-02-17 |
| DE3773026D1 (de) | 1991-10-24 |
| DD263287A5 (de) | 1988-12-28 |
| CS271469B2 (en) | 1990-10-12 |
| ES2037676T3 (es) | 1993-07-01 |
| DK155387D0 (da) | 1987-03-26 |
| DK155387A (da) | 1987-09-30 |
| EP0239907B1 (de) | 1991-09-18 |
| ATE67483T1 (de) | 1991-10-15 |
| ZA872254B (en) | 1987-11-25 |
| AU7072387A (en) | 1987-10-15 |
| AU582043B2 (en) | 1989-03-09 |
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