CS191970B2 - Process for preparing unsaturated anhydrous gamma crystalline natrium salt of 7-/d-alpha-formyloxy-alpha phenylacetamido/-3-/1-methyl-1h-tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid - Google Patents

Process for preparing unsaturated anhydrous gamma crystalline natrium salt of 7-/d-alpha-formyloxy-alpha phenylacetamido/-3-/1-methyl-1h-tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid

Info

Publication number
CS191970B2
CS191970B2 CS762264A CS226476A CS191970B2 CS 191970 B2 CS191970 B2 CS 191970B2 CS 762264 A CS762264 A CS 762264A CS 226476 A CS226476 A CS 226476A CS 191970 B2 CS191970 B2 CS 191970B2
Authority
CS
Czechoslovakia
Prior art keywords
alpha
ylthiomethyl
phenylacetamido
cephem
formyloxy
Prior art date
Application number
CS762264A
Other languages
Czech (cs)
English (en)
Inventor
Kuo S Yang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS191970B2 publication Critical patent/CS191970B2/cs

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CS762264A 1975-04-11 1976-04-06 Process for preparing unsaturated anhydrous gamma crystalline natrium salt of 7-/d-alpha-formyloxy-alpha phenylacetamido/-3-/1-methyl-1h-tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid CS191970B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/567,324 US4006138A (en) 1975-04-11 1975-04-11 Crystalline form of sodium O-formylcefamandole

Publications (1)

Publication Number Publication Date
CS191970B2 true CS191970B2 (en) 1979-07-31

Family

ID=24266692

Family Applications (1)

Application Number Title Priority Date Filing Date
CS762264A CS191970B2 (en) 1975-04-11 1976-04-06 Process for preparing unsaturated anhydrous gamma crystalline natrium salt of 7-/d-alpha-formyloxy-alpha phenylacetamido/-3-/1-methyl-1h-tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid

Country Status (31)

Country Link
US (1) US4006138A (sv)
JP (1) JPS51123812A (sv)
AR (1) AR210880A1 (sv)
AT (1) AT343806B (sv)
AU (1) AU500013B2 (sv)
BE (1) BE840179A (sv)
CA (1) CA1045114A (sv)
CH (1) CH621554A5 (sv)
CS (1) CS191970B2 (sv)
DD (1) DD125950A5 (sv)
DE (1) DE2614669C2 (sv)
DK (1) DK148022C (sv)
ES (1) ES446907A1 (sv)
FI (1) FI65069C (sv)
FR (1) FR2306698A1 (sv)
GB (1) GB1546898A (sv)
GR (1) GR59912B (sv)
HU (1) HU175592B (sv)
IL (1) IL49100A (sv)
LU (1) LU74740A1 (sv)
MX (1) MX3687E (sv)
NL (1) NL184258C (sv)
NO (1) NO151748C (sv)
OA (1) OA05290A (sv)
PL (1) PL104803B1 (sv)
PT (1) PT64917B (sv)
RO (1) RO68501A (sv)
SE (1) SE435290B (sv)
SU (1) SU668608A3 (sv)
YU (1) YU40643B (sv)
ZA (1) ZA761103B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7503274L (sv) * 1974-04-11 1975-10-13 Ciba Geigy Ag Cefalosporin
US4085277A (en) * 1975-01-30 1978-04-18 Fujisawa Pharmaceutical Co., Ltd. 7(2-Phenyl or thienyl-2-isonicotinoyloxyacetamido)-3-(1-methyl-1-H tetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid
FR2400519A1 (fr) * 1977-08-17 1979-03-16 Roussel Uclaf Forme cristalline du sel de sodium d'un derive oximine de l'acide 7-amino-thiazolyl acetamido cephalosporanique, son procede de preparation et son application comme medicament
US4168376A (en) * 1978-06-05 1979-09-18 Eli Lilly And Company Process for crystalline sodium cefamandole
US4946838A (en) * 1981-07-13 1990-08-07 E. R. Squibb & Sons, Inc. Crystalline anhydrous aztreonam
EP0432297A1 (en) * 1989-12-13 1991-06-19 Technologitschen Kombinat Sa Promischlena Mikrobiologia A method for the preparation of the sodium salt of O-formyl cefamandole
US5492903A (en) * 1990-06-19 1996-02-20 Takeda Chemical Industries Ltd. Crystalline esters of (+)-(5R, 6S)-6-[(R)-1-hydroxyethyl]-3-(3-pyridyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]he
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
WO2013057196A1 (en) * 2011-10-20 2013-04-25 Dsm Sinochem Pharmaceuticals Netherlands B.V. Process for the preparation of cefamandole nafate
CN104530086B (zh) * 2014-12-16 2015-12-09 天津大学 头孢孟多酯钠化合物的新晶型及其结晶制备方法
CN105037392A (zh) * 2015-08-13 2015-11-11 青岛蓝盛洋医药生物科技有限责任公司 一种杀菌药物头孢孟多酯钠化合物及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887551A (en) * 1964-11-04 1975-06-03 Glaxo Lab Ltd Crystalline forms of cephaloridine
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds

Also Published As

Publication number Publication date
PT64917B (en) 1977-08-24
PL104803B1 (pl) 1979-09-29
ZA761103B (en) 1977-10-26
CA1045114A (en) 1978-12-26
FR2306698B1 (sv) 1979-10-05
NO151748C (no) 1985-06-05
JPS6110474B2 (sv) 1986-03-29
SU668608A3 (ru) 1979-06-15
AR210880A1 (es) 1977-09-30
DE2614669C2 (de) 1984-09-27
JPS51123812A (en) 1976-10-28
AU1143576A (en) 1977-09-01
NO761017L (sv) 1976-10-12
NL184258B (nl) 1989-01-02
YU79276A (en) 1982-10-31
IL49100A (en) 1979-03-12
YU40643B (en) 1986-04-30
FI65069B (fi) 1983-11-30
AT343806B (de) 1978-06-26
SE7602565L (sv) 1976-10-12
HU175592B (hu) 1980-09-28
IL49100A0 (en) 1976-04-30
DK148022B (da) 1985-02-04
GR59912B (en) 1978-03-20
ATA258476A (de) 1977-10-15
FI65069C (fi) 1984-03-12
PT64917A (en) 1976-04-01
FI760788A (sv) 1976-10-12
DD125950A5 (sv) 1977-06-01
NL7603660A (nl) 1976-10-13
FR2306698A1 (fr) 1976-11-05
DK148022C (da) 1985-07-22
BE840179A (fr) 1976-09-30
OA05290A (fr) 1981-02-28
US4006138A (en) 1977-02-01
GB1546898A (en) 1979-05-31
CH621554A5 (sv) 1981-02-13
SE435290B (sv) 1984-09-17
DK150676A (da) 1976-10-12
AU500013B2 (en) 1979-05-10
MX3687E (es) 1981-04-29
DE2614669A1 (de) 1976-10-21
NL184258C (nl) 1989-06-01
ES446907A1 (es) 1977-09-16
RO68501A (ro) 1981-04-30
NO151748B (no) 1985-02-18
LU74740A1 (sv) 1976-11-11

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