CS185245B2 - Process for preparing new substituted 3-(2-/4-phenyl-1-piperazinyl/ethyl)indolines - Google Patents

Process for preparing new substituted 3-(2-/4-phenyl-1-piperazinyl/ethyl)indolines

Info

Publication number
CS185245B2
CS185245B2 CS7600000251A CS25176A CS185245B2 CS 185245 B2 CS185245 B2 CS 185245B2 CS 7600000251 A CS7600000251 A CS 7600000251A CS 25176 A CS25176 A CS 25176A CS 185245 B2 CS185245 B2 CS 185245B2
Authority
CS
Czechoslovakia
Prior art keywords
indolines
piperazinyl
phenyl
ethyl
new substituted
Prior art date
Application number
CS7600000251A
Other languages
Czech (cs)
English (en)
Inventor
George R Allen
Francis J Evoy
Vries Vern G De
Daniel B Moran
Ruddy Littell
Original Assignee
George R Allen
Francis J Evoy
Vries Vern G De
Daniel B Moran
Ruddy Littell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by George R Allen, Francis J Evoy, Vries Vern G De, Daniel B Moran, Ruddy Littell filed Critical George R Allen
Publication of CS185245B2 publication Critical patent/CS185245B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS7600000251A 1971-05-27 1972-05-19 Process for preparing new substituted 3-(2-/4-phenyl-1-piperazinyl/ethyl)indolines CS185245B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14770071A 1971-05-27 1971-05-27

Publications (1)

Publication Number Publication Date
CS185245B2 true CS185245B2 (en) 1978-09-15

Family

ID=22522572

Family Applications (3)

Application Number Title Priority Date Filing Date
CS7600000248A CS185244B2 (en) 1971-05-27 1972-05-19 Process for preparing new substituted 3-(2-/phenyl-1-piperazinyl/ethyl)indolines
CS7200003454A CS185203B2 (en) 1971-05-27 1972-05-19 Process for preparing new substituted 3-(2-/4-phenyl-1-piperazinyl/ethyl)indolines
CS7600000251A CS185245B2 (en) 1971-05-27 1972-05-19 Process for preparing new substituted 3-(2-/4-phenyl-1-piperazinyl/ethyl)indolines

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CS7600000248A CS185244B2 (en) 1971-05-27 1972-05-19 Process for preparing new substituted 3-(2-/phenyl-1-piperazinyl/ethyl)indolines
CS7200003454A CS185203B2 (en) 1971-05-27 1972-05-19 Process for preparing new substituted 3-(2-/4-phenyl-1-piperazinyl/ethyl)indolines

Country Status (20)

Country Link
US (1) US3751416A (xx)
AR (4) AR194595A1 (xx)
BE (1) BE784012A (xx)
BG (5) BG18866A3 (xx)
CA (1) CA1014154A (xx)
CH (5) CH579563A5 (xx)
CS (3) CS185244B2 (xx)
DD (1) DD100471A5 (xx)
DE (1) DE2225765A1 (xx)
ES (4) ES403245A1 (xx)
FR (1) FR2139158B1 (xx)
GB (2) GB1382916A (xx)
HU (3) HU168720B (xx)
NL (1) NL7207129A (xx)
NO (1) NO136795C (xx)
PL (4) PL81987B1 (xx)
RO (4) RO60145A (xx)
SE (4) SE397524B (xx)
SU (4) SU489321A3 (xx)
ZA (1) ZA722916B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888860A (en) * 1974-01-07 1975-06-10 Colgate Palmolive Co 3-(2-(4-thienoylpiperazin-1-yl)ethyl)indoles
US4089853A (en) * 1977-02-09 1978-05-16 American Cyanamid Company Process for the preparation of cis-5,6-dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)-ethyl]indoline
FR2421900A1 (fr) * 1977-03-17 1979-11-02 Sauba Lab Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques
GR65270B (en) 1978-10-10 1980-07-31 Fujisawa Pharmaceutical Co Isatin derivatives and processes for the preparation thereof
US4224330A (en) * 1979-09-13 1980-09-23 Zoecon Corporation Esters and thiolesters of benzothienyl acids
US4411900A (en) * 1980-01-03 1983-10-25 Fujisawa Pharmaceutical Co., Ltd. Benzhydrylpiperozinyl thiazole derivatives and pharmaceutical composition comprising the same
US4302589A (en) * 1980-05-08 1981-11-24 American Cyanamid Company Cis-mono and disubstituted-2-methyl-3-[(piperazinyl) and (piperidino)ethyl]indolines, intermediates for their preparation and methods of preparation
CA1248531A (en) * 1984-04-17 1989-01-10 Jeffrey C. Watkins 4-substituted piperazine-2-carboxylic acids
JPH05255089A (ja) * 1991-12-18 1993-10-05 Sanwa Kagaku Kenkyusho Co Ltd 抗ウイルス剤

Also Published As

Publication number Publication date
CH583700A5 (xx) 1977-01-14
BG19593A3 (bg) 1975-06-25
RO63715A (fr) 1978-10-15
HU168720B (xx) 1976-07-28
US3751416A (en) 1973-08-07
PL92627B1 (xx) 1977-04-30
CH582142A5 (xx) 1976-11-30
ES403245A1 (es) 1975-04-16
AR210562A1 (es) 1977-08-31
RO64489A (fr) 1979-05-15
BG19151A3 (bg) 1975-04-30
SU488408A3 (ru) 1975-10-15
BG20791A3 (xx) 1975-12-20
GB1382916A (en) 1975-02-05
HU167203B (xx) 1975-09-27
SE395455B (sv) 1977-08-15
SE397524B (sv) 1977-11-07
CH582172A5 (xx) 1976-11-30
CS185244B2 (en) 1978-09-15
SE7600531L (sv) 1976-01-20
CH583701A5 (xx) 1977-01-14
CH579563A5 (xx) 1976-09-15
SE397525B (sv) 1977-11-07
NO136795B (no) 1977-08-01
AU4191872A (en) 1973-11-08
NL7207129A (xx) 1972-11-29
PL92634B1 (xx) 1977-04-30
FR2139158A1 (xx) 1973-01-05
ES409284A1 (es) 1976-03-16
PL92635B1 (xx) 1977-04-30
ZA722916B (en) 1973-02-28
BG19594A3 (bg) 1975-06-25
SU489321A3 (ru) 1975-10-25
DE2225765A1 (de) 1972-12-07
RO60145A (xx) 1976-09-15
CS185203B2 (en) 1978-09-15
NO136795C (no) 1977-11-09
AR208647A1 (es) 1977-02-28
AR194595A1 (es) 1973-07-31
BG18866A3 (bg) 1975-03-20
RO63730A (fr) 1978-11-15
CA1014154A (en) 1977-07-19
FR2139158B1 (xx) 1975-10-17
GB1382917A (en) 1975-02-05
AR208646A1 (es) 1977-02-28
DD100471A5 (xx) 1973-09-20
ES409281A1 (es) 1976-03-16
PL81987B1 (xx) 1975-10-31
SU575024A3 (ru) 1977-09-30
ES409282A1 (es) 1976-03-16
SU489322A3 (ru) 1975-10-25
HU166178B (xx) 1975-02-28
BE784012A (fr) 1972-11-27

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