CR9676A - Inmunofenotipo e inmunogenicidad de celulas derivadas de tejido adiposo humano - Google Patents

Inmunofenotipo e inmunogenicidad de celulas derivadas de tejido adiposo humano

Info

Publication number
CR9676A
CR9676A CR9676A CR9676A CR9676A CR 9676 A CR9676 A CR 9676A CR 9676 A CR9676 A CR 9676A CR 9676 A CR9676 A CR 9676A CR 9676 A CR9676 A CR 9676A
Authority
CR
Costa Rica
Prior art keywords
adipose tissue
immunogenicity
cells derived
immunofenotype
human adipose
Prior art date
Application number
CR9676A
Other languages
English (en)
Inventor
Kevin R Mcintosh
Ii James B Mitchell
Jeffrey M Gimble
Original Assignee
Cognate Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cognate Therapeutics Inc filed Critical Cognate Therapeutics Inc
Publication of CR9676A publication Critical patent/CR9676A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invencion abarca metodos y composiciones para generar una celula estromal derivada de tejido adiposo aislado que exhibe un bajo nivel de inmunogenicidad; la presente invencion abarca metodos y composiciones para reducir una respuesta inmune asociada con el transplante mediante la administracion al recipiente con una cantidad de celulas estromales derivadas de tejido adiposo efectivas para reducir o inhibir rechazo del hospedero y/o la enfermedad hospedero contra injerto.
CR9676A 2005-07-15 2008-01-21 Inmunofenotipo e inmunogenicidad de celulas derivadas de tejido adiposo humano CR9676A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69955305P 2005-07-15 2005-07-15

Publications (1)

Publication Number Publication Date
CR9676A true CR9676A (es) 2008-02-21

Family

ID=37669427

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9676A CR9676A (es) 2005-07-15 2008-01-21 Inmunofenotipo e inmunogenicidad de celulas derivadas de tejido adiposo humano

Country Status (13)

Country Link
US (2) US20070122393A1 (es)
EP (1) EP1910519A4 (es)
JP (1) JP2009501526A (es)
KR (1) KR20080039903A (es)
CN (1) CN101374945A (es)
AU (1) AU2006270133A1 (es)
BR (1) BRPI0613190A2 (es)
CA (1) CA2615391A1 (es)
CR (1) CR9676A (es)
IL (1) IL188596A0 (es)
RU (1) RU2008105675A (es)
TW (1) TW200726474A (es)
WO (1) WO2007011797A2 (es)

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US8147824B2 (en) 1999-08-05 2012-04-03 Athersys, Inc. Immunomodulatory properties of multipotent adult progenitor cells and uses thereof
US11000546B2 (en) 2005-11-09 2021-05-11 Athersys, Inc. Immunomodulatory properties of MAPCs and uses thereof
US10117900B2 (en) * 2005-11-09 2018-11-06 Athersys, Inc. MAPC treatment of brain injuries and diseases
CA3124132A1 (en) 2006-01-23 2007-08-02 Abt Holding Company Mapc therapeutics without adjunctive immunosuppressive treatment
US8241621B2 (en) * 2006-12-18 2012-08-14 Medistem Laboratories Stem cell mediated treg activation/expansion for therapeutic immune modulation
US20100278788A1 (en) * 2008-01-11 2010-11-04 Bone Therapeutics, S.A. Osteogenic Differentiation Of Bone Marrow Stem Cells And Mesenchymal Stem Cells Using A Combination Of Growth Factors
US20130164267A1 (en) * 2008-06-11 2013-06-27 Cell4Vet Corporation Adipose tissue-derived stem cells for veterinary use
US9096827B2 (en) * 2008-09-02 2015-08-04 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
US11090387B2 (en) * 2008-12-22 2021-08-17 The Trustees Of The University Of Pennsylvania Hydrolytically degradable polysaccharide hydrogels
WO2010126194A1 (ko) 2009-04-28 2010-11-04 (주) 안트로젠 누공 치료를 위한 자가 및 동종의 지방 유래 스트로마 줄기세포 조성물
JP5710885B2 (ja) * 2010-02-25 2015-04-30 オリンパス株式会社 脂肪由来細胞の賦活化方法および移植材の製造方法
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
WO2011156642A1 (en) * 2010-06-11 2011-12-15 Tengion, Inc. Erythropoietin-expressing adipose cell populations
JP5934783B2 (ja) * 2011-05-03 2016-06-15 イミュノバティブ セラピーズ，リミテッド 生細胞を含む生物学的薬剤の取り扱い方法
US9427450B2 (en) 2012-01-31 2016-08-30 Xon Cells, Inc. Therapeutic immune modulation by stem cell secreted exosomes
EP2818173B1 (en) * 2012-02-24 2021-09-22 Saeki, Masanori Cell preparation including fat cell
MX2016001247A (es) 2013-07-30 2016-08-17 Musculoskeletal Transplant Foundation Matrices derivadas de tejido suave acelular y metodos para preparar las mismas.
EP3297694A1 (en) 2015-05-21 2018-03-28 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
US20180325957A1 (en) * 2015-10-23 2018-11-15 Rigshospitalet Stem cell therapy based on adipose-derived stem cells

Family Cites Families (18)

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US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4353888A (en) * 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4678470A (en) * 1985-05-29 1987-07-07 American Hospital Supply Corporation Bone-grafting material
US5158881A (en) * 1987-11-17 1992-10-27 Brown University Research Foundation Method and system for encapsulating cells in a tubular extrudate in separate cell compartments
US5283187A (en) * 1987-11-17 1994-02-01 Brown University Research Foundation Cell culture-containing tubular capsule produced by co-extrusion
DE3829752A1 (de) * 1988-09-01 1990-03-22 Akzo Gmbh Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration
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US5082670A (en) * 1988-12-15 1992-01-21 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system
US5084350A (en) * 1990-02-16 1992-01-28 The Royal Institution For The Advance Of Learning (Mcgill University) Method for encapsulating biologically active material including cells
US5618531A (en) * 1990-10-19 1997-04-08 New York University Method for increasing the viability of cells which are administered to the brain or spinal cord
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DK1975243T3 (da) * 1998-12-07 2010-06-28 Univ Duke BODIPY-aminoacetaldehyddiethylacetal
KR100968164B1 (ko) * 1999-03-10 2010-07-06 더 리전츠 오브 더 유니버시티 오브 캘리포니아 지방 유래 간세포 및 격자
US6936281B2 (en) * 2001-03-21 2005-08-30 University Of South Florida Human mesenchymal progenitor cell
ES2560847T3 (es) * 2002-07-31 2016-02-23 Yves Saint-Laurent Parfums Células madre procedentes de tejido adiposo y células diferenciadas procedentes de estas células

Also Published As

Publication number Publication date
TW200726474A (en) 2007-07-16
WO2007011797A2 (en) 2007-01-25
CA2615391A1 (en) 2007-01-25
KR20080039903A (ko) 2008-05-07
EP1910519A2 (en) 2008-04-16
IL188596A0 (en) 2008-04-13
US20110158959A1 (en) 2011-06-30
RU2008105675A (ru) 2009-08-20
EP1910519A4 (en) 2009-02-11
WO2007011797A3 (en) 2007-10-04
BRPI0613190A2 (pt) 2010-12-21
US20070122393A1 (en) 2007-05-31
JP2009501526A (ja) 2009-01-22
AU2006270133A1 (en) 2007-01-25
CN101374945A (zh) 2009-02-25

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Legal Events

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