CR9676A - Inmunofenotipo e inmunogenicidad de celulas derivadas de tejido adiposo humano - Google Patents

Inmunofenotipo e inmunogenicidad de celulas derivadas de tejido adiposo humano

Info

Publication number
CR9676A
CR9676A CR9676A CR9676A CR9676A CR 9676 A CR9676 A CR 9676A CR 9676 A CR9676 A CR 9676A CR 9676 A CR9676 A CR 9676A CR 9676 A CR9676 A CR 9676A
Authority
CR
Costa Rica
Prior art keywords
adipose tissue
immunogenicity
cells derived
immunofenotype
human adipose
Prior art date
Application number
CR9676A
Other languages
English (en)
Inventor
Kevin R Mcintosh
Ii James B Mitchell
Jeffrey M Gimble
Original Assignee
Cognate Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cognate Therapeutics Inc filed Critical Cognate Therapeutics Inc
Publication of CR9676A publication Critical patent/CR9676A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invencion abarca metodos y composiciones para generar una celula estromal derivada de tejido adiposo aislado que exhibe un bajo nivel de inmunogenicidad; la presente invencion abarca metodos y composiciones para reducir una respuesta inmune asociada con el transplante mediante la administracion al recipiente con una cantidad de celulas estromales derivadas de tejido adiposo efectivas para reducir o inhibir rechazo del hospedero y/o la enfermedad hospedero contra injerto.
CR9676A 2005-07-15 2008-01-21 Inmunofenotipo e inmunogenicidad de celulas derivadas de tejido adiposo humano CR9676A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69955305P 2005-07-15 2005-07-15

Publications (1)

Publication Number Publication Date
CR9676A true CR9676A (es) 2008-02-21

Family

ID=37669427

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9676A CR9676A (es) 2005-07-15 2008-01-21 Inmunofenotipo e inmunogenicidad de celulas derivadas de tejido adiposo humano

Country Status (13)

Country Link
US (2) US20070122393A1 (es)
EP (1) EP1910519A4 (es)
JP (1) JP2009501526A (es)
KR (1) KR20080039903A (es)
CN (1) CN101374945A (es)
AU (1) AU2006270133A1 (es)
BR (1) BRPI0613190A2 (es)
CA (1) CA2615391A1 (es)
CR (1) CR9676A (es)
IL (1) IL188596A0 (es)
RU (1) RU2008105675A (es)
TW (1) TW200726474A (es)
WO (1) WO2007011797A2 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8147824B2 (en) 1999-08-05 2012-04-03 Athersys, Inc. Immunomodulatory properties of multipotent adult progenitor cells and uses thereof
US11000546B2 (en) 2005-11-09 2021-05-11 Athersys, Inc. Immunomodulatory properties of MAPCs and uses thereof
US10117900B2 (en) * 2005-11-09 2018-11-06 Athersys, Inc. MAPC treatment of brain injuries and diseases
NZ727755A (en) 2006-01-23 2023-01-27 Abt Holding Co Mapc therapeutics without adjunctive immunosuppressive treatment
US8241621B2 (en) * 2006-12-18 2012-08-14 Medistem Laboratories Stem cell mediated treg activation/expansion for therapeutic immune modulation
US20100278788A1 (en) * 2008-01-11 2010-11-04 Bone Therapeutics, S.A. Osteogenic Differentiation Of Bone Marrow Stem Cells And Mesenchymal Stem Cells Using A Combination Of Growth Factors
US20130164267A1 (en) * 2008-06-11 2013-06-27 Cell4Vet Corporation Adipose tissue-derived stem cells for veterinary use
US9096827B2 (en) * 2008-09-02 2015-08-04 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
US11090387B2 (en) * 2008-12-22 2021-08-17 The Trustees Of The University Of Pennsylvania Hydrolytically degradable polysaccharide hydrogels
DK2425844T3 (da) 2009-04-28 2014-06-16 Anterogen Co Ltd Autolog og allogen stromastamcellesammensætning, der stammer fra fedtvæv, til behandling af fistler
JP5710885B2 (ja) * 2010-02-25 2015-04-30 オリンパス株式会社 脂肪由来細胞の賦活化方法および移植材の製造方法
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
WO2011156642A1 (en) * 2010-06-11 2011-12-15 Tengion, Inc. Erythropoietin-expressing adipose cell populations
PL2704741T3 (pl) 2011-05-03 2018-02-28 Immunovative Therapies, Ltd. Sposoby postępowania z lekami biologicznymi zawierającymi żywe komórki
US9427450B2 (en) 2012-01-31 2016-08-30 Xon Cells, Inc. Therapeutic immune modulation by stem cell secreted exosomes
RU2746915C2 (ru) * 2012-02-24 2021-04-22 Масанори САЕКИ Клеточный препарат, включающий жировые клетки
EP3027235A1 (en) 2013-07-30 2016-06-08 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
CA3177726A1 (en) 2015-05-21 2016-11-24 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
SI3365432T1 (sl) * 2015-10-23 2020-08-31 Rigshospitalet Terapija z matičnimi celicami, na osnovi matičnih celic iz adipoze
CN116056716A (zh) * 2020-05-15 2023-05-02 首尔大学校产学协力团 利用从脂肪组织分离出来的基质血管组分的树突状细胞的激活功能的免疫反应增强用组合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4353888A (en) * 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4678470A (en) * 1985-05-29 1987-07-07 American Hospital Supply Corporation Bone-grafting material
US5158881A (en) * 1987-11-17 1992-10-27 Brown University Research Foundation Method and system for encapsulating cells in a tubular extrudate in separate cell compartments
US5283187A (en) * 1987-11-17 1994-02-01 Brown University Research Foundation Cell culture-containing tubular capsule produced by co-extrusion
DE3829752A1 (de) * 1988-09-01 1990-03-22 Akzo Gmbh Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration
DE3829766A1 (de) * 1988-09-01 1990-03-22 Akzo Gmbh Verfahren zur herstellung von membranen
US5082670A (en) * 1988-12-15 1992-01-21 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system
US5084350A (en) * 1990-02-16 1992-01-28 The Royal Institution For The Advance Of Learning (Mcgill University) Method for encapsulating biologically active material including cells
US5618531A (en) * 1990-10-19 1997-04-08 New York University Method for increasing the viability of cells which are administered to the brain or spinal cord
US5571083A (en) * 1994-02-18 1996-11-05 Lemelson; Jerome H. Method and system for cell transplantation
US6342479B1 (en) * 1997-04-08 2002-01-29 Societe De Counseils De Recherches Et D'applications Scientifiques, Sas Prolonging survival of transplanted pancreatic cells
US5968829A (en) * 1997-09-05 1999-10-19 Cytotherapeutics, Inc. Human CNS neural stem cells
US7622557B2 (en) * 1998-05-28 2009-11-24 St. Jude Children's Research Hospital Antibodies having binding specificity for the extracellular domain of a breast cancer resistance protein (BCRP)
EP1975243B1 (en) * 1998-12-07 2010-03-24 Duke University BODIPY aminoacetaldehyde diethyl acetal
KR100979664B1 (ko) * 1999-03-10 2010-09-02 유니버시티 오브 피츠버그 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 지방 유래 간세포 및 격자
US6936281B2 (en) * 2001-03-21 2005-08-30 University Of South Florida Human mesenchymal progenitor cell
EP1527161B1 (fr) * 2002-07-31 2015-10-28 Yves Saint-Laurent Parfums Cellules souches issues de tissu adipeux et cellules differenciees issues de ces cellules

Also Published As

Publication number Publication date
EP1910519A2 (en) 2008-04-16
RU2008105675A (ru) 2009-08-20
CN101374945A (zh) 2009-02-25
KR20080039903A (ko) 2008-05-07
US20110158959A1 (en) 2011-06-30
TW200726474A (en) 2007-07-16
JP2009501526A (ja) 2009-01-22
EP1910519A4 (en) 2009-02-11
CA2615391A1 (en) 2007-01-25
WO2007011797A3 (en) 2007-10-04
IL188596A0 (en) 2008-04-13
BRPI0613190A2 (pt) 2010-12-21
US20070122393A1 (en) 2007-05-31
WO2007011797A2 (en) 2007-01-25
AU2006270133A1 (en) 2007-01-25

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