CR9268A - Nuevo derivado de diazabiciclononeno - Google Patents
Nuevo derivado de diazabiciclononenoInfo
- Publication number
- CR9268A CR9268A CR9268A CR9268A CR9268A CR 9268 A CR9268 A CR 9268A CR 9268 A CR9268 A CR 9268A CR 9268 A CR9268 A CR 9268A CR 9268 A CR9268 A CR 9268A
- Authority
- CR
- Costa Rica
- Prior art keywords
- derivative
- new
- diazabiciclononene
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/504—Pyridazines; Hydrogenated pyridazines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
La invencion se refiere a un nuevo derivado 3,9-diazabiciclo[3.3.1]nonero y sus enantiomeros y a su uso como ingrediente activo en la preparacion de composiciones farmaceuticas. La invencion tambien se refiere a aspectos relacionados que incluyen procesos para la preparacion de los compuestos, composiciones farmaceuticas que contienen al menos un compuesto de la formula (I) o (I) y especialmente a su uso como inhibidores de renina.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP2005000842 | 2005-01-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR9268A true CR9268A (es) | 2007-10-23 |
Family
ID=36263952
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR9268A CR9268A (es) | 2005-01-28 | 2007-07-20 | Nuevo derivado de diazabiciclononeno |
Country Status (20)
Country | Link |
---|---|
US (1) | US7915259B2 (es) |
EP (1) | EP1846407B1 (es) |
JP (1) | JP4111533B1 (es) |
KR (1) | KR100938364B1 (es) |
CN (1) | CN101107248A (es) |
AR (1) | AR052894A1 (es) |
AT (1) | ATE514697T1 (es) |
AU (1) | AU2006208992A1 (es) |
CA (1) | CA2595986A1 (es) |
CR (1) | CR9268A (es) |
ES (1) | ES2367267T3 (es) |
IL (1) | IL184885A0 (es) |
MA (1) | MA29267B1 (es) |
MX (1) | MX2007009004A (es) |
NI (1) | NI200700189A (es) |
NO (1) | NO20074303L (es) |
RU (1) | RU2007132438A (es) |
TW (1) | TW200637861A (es) |
WO (1) | WO2006079988A1 (es) |
ZA (1) | ZA200705752B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2577084A1 (en) * | 2004-08-25 | 2006-03-02 | Olivier Bezencon | Bicyclononene derivatives as renin inhibitors |
US7799805B2 (en) * | 2005-05-27 | 2010-09-21 | Actelion Pharmaceuticals Ltd. | Piperidine carboxylic acid amide derivatives |
WO2007088514A1 (en) * | 2006-02-02 | 2007-08-09 | Actelion Pharmaceuticals Ltd | Secondary amines as renin inhibitors |
JP2009529033A (ja) * | 2006-03-08 | 2009-08-13 | アクテリオン ファーマシューティカルズ リミテッド | 新規アミン |
CL2007002689A1 (es) * | 2006-09-18 | 2008-04-18 | Vitae Pharmaceuticals Inc | Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras. |
WO2008088690A2 (en) * | 2007-01-12 | 2008-07-24 | Merck & Co., Inc. | A process for preparing diazabicyclo[3.3.1] nonane compounds |
US8129538B1 (en) | 2007-03-28 | 2012-03-06 | Takeda Pharmaceutical Company Limited | Renin inhibitors |
CA2688057A1 (en) | 2007-05-24 | 2008-11-27 | Merck Frosst Canada Ltd. | Novel case of renin inhibitors |
JP2010536800A (ja) | 2007-08-20 | 2010-12-02 | メルク フロスト カナダ リミテツド | レニン阻害剤 |
NZ589019A (en) | 2008-05-05 | 2012-10-26 | Merck Frosst Canada Ltd | 3, 4 - substituted piperidine derivatives as renin inhibitors |
EP3060560A1 (en) | 2013-10-25 | 2016-08-31 | Blueprint Medicines Corporation | Inhibitors of the fibroblast growth factor receptor |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TR199800409T1 (xx) * | 1995-09-07 | 1998-05-21 | F.Hoffmann-La Roche Ag | Kalp ve b�brek yetersizli�inin tedavii�in yeni 4-(oksialkoksifenil)-3-oksi-piperidinler |
PL372141A1 (en) | 2002-04-29 | 2005-07-11 | Actelion Pharmaceuticals Ltd. | 7-aryl-3,9-diazabicyclo[3.3.1]non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases |
US20060217371A1 (en) * | 2003-04-28 | 2006-09-28 | Olivier Bezencon | Diazabicyclononene and tetrahydropyriddine derivatives as renin inhibitors |
CN1780838A (zh) * | 2003-05-02 | 2006-05-31 | 埃科特莱茵药品有限公司 | 新型二氮杂双环壬烯衍生物 |
US20060223795A1 (en) * | 2003-05-02 | 2006-10-05 | Oliver Bezencon | Novel diazabicyclononene derivatives |
WO2004105762A1 (en) * | 2003-05-30 | 2004-12-09 | Actelion Pharmaceuticals Ltd | Medical use of diazabicyclononene derivatives as inhibitors of parasite aspartic proteases |
-
2006
- 2006-01-26 CA CA002595986A patent/CA2595986A1/en not_active Abandoned
- 2006-01-26 AT AT06710758T patent/ATE514697T1/de not_active IP Right Cessation
- 2006-01-26 AU AU2006208992A patent/AU2006208992A1/en not_active Abandoned
- 2006-01-26 MX MX2007009004A patent/MX2007009004A/es not_active Application Discontinuation
- 2006-01-26 WO PCT/IB2006/050285 patent/WO2006079988A1/en active Application Filing
- 2006-01-26 KR KR1020077019567A patent/KR100938364B1/ko not_active IP Right Cessation
- 2006-01-26 EP EP06710758A patent/EP1846407B1/en active Active
- 2006-01-26 ES ES06710758T patent/ES2367267T3/es active Active
- 2006-01-26 CN CNA2006800027614A patent/CN101107248A/zh active Pending
- 2006-01-26 JP JP2007551803A patent/JP4111533B1/ja not_active Expired - Fee Related
- 2006-01-26 RU RU2007132438/04A patent/RU2007132438A/ru not_active Application Discontinuation
- 2006-01-26 US US11/795,850 patent/US7915259B2/en not_active Expired - Fee Related
- 2006-01-27 TW TW095103557A patent/TW200637861A/zh unknown
- 2006-01-27 AR ARP060100313A patent/AR052894A1/es not_active Application Discontinuation
-
2007
- 2007-07-12 ZA ZA200705752A patent/ZA200705752B/xx unknown
- 2007-07-20 CR CR9268A patent/CR9268A/es not_active Application Discontinuation
- 2007-07-26 IL IL184885A patent/IL184885A0/en unknown
- 2007-07-27 NI NI200700189A patent/NI200700189A/es unknown
- 2007-08-22 NO NO20074303A patent/NO20074303L/no not_active Application Discontinuation
- 2007-08-24 MA MA30163A patent/MA29267B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
AU2006208992A1 (en) | 2006-08-03 |
EP1846407B1 (en) | 2011-06-29 |
WO2006079988A1 (en) | 2006-08-03 |
US7915259B2 (en) | 2011-03-29 |
MA29267B1 (fr) | 2008-02-01 |
ES2367267T3 (es) | 2011-10-31 |
JP2008528478A (ja) | 2008-07-31 |
US20080161313A1 (en) | 2008-07-03 |
MX2007009004A (es) | 2007-09-14 |
KR20080001707A (ko) | 2008-01-03 |
RU2007132438A (ru) | 2009-03-10 |
ZA200705752B (en) | 2009-02-25 |
IL184885A0 (en) | 2007-12-03 |
EP1846407A1 (en) | 2007-10-24 |
AR052894A1 (es) | 2007-04-11 |
NO20074303L (no) | 2007-08-22 |
ATE514697T1 (de) | 2011-07-15 |
KR100938364B1 (ko) | 2010-01-22 |
TW200637861A (en) | 2006-11-01 |
JP4111533B1 (ja) | 2008-07-02 |
CN101107248A (zh) | 2008-01-16 |
CA2595986A1 (en) | 2006-08-03 |
NI200700189A (es) | 2008-04-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal (granting procedure) |