CR10474A - Derivados de benzozazol y benzotiazol como ligandos de 5-hidroxitriptamina-6 - Google Patents
Derivados de benzozazol y benzotiazol como ligandos de 5-hidroxitriptamina-6Info
- Publication number
- CR10474A CR10474A CR10474A CR10474A CR10474A CR 10474 A CR10474 A CR 10474A CR 10474 A CR10474 A CR 10474A CR 10474 A CR10474 A CR 10474A CR 10474 A CR10474 A CR 10474A
- Authority
- CR
- Costa Rica
- Prior art keywords
- hydroxythyriptamine
- benzozazol
- benzotiazol
- ligands
- derivatives
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title 1
- 108091005435 5-HT6 receptors Proteins 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La presente invencion suministra un compuesto de formula I y el uso de este para el tratamiento de un trastorno del sistema nervioso central relacionado con o afectado por el receptor 5-HT6.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80999606P | 2006-06-01 | 2006-06-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR10474A true CR10474A (es) | 2009-01-07 |
Family
ID=38668755
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR10474A CR10474A (es) | 2006-06-01 | 2008-12-01 | Derivados de benzozazol y benzotiazol como ligandos de 5-hidroxitriptamina-6 |
Country Status (17)
Country | Link |
---|---|
US (1) | US7501421B2 (es) |
EP (1) | EP2024348A2 (es) |
JP (1) | JP2009538909A (es) |
KR (1) | KR20090023641A (es) |
CN (1) | CN101490022A (es) |
AR (1) | AR061147A1 (es) |
AU (1) | AU2007255041A1 (es) |
BR (1) | BRPI0712444A2 (es) |
CA (1) | CA2659701A1 (es) |
CR (1) | CR10474A (es) |
EC (1) | ECSP088930A (es) |
IL (1) | IL195590A0 (es) |
MX (1) | MX2008015328A (es) |
NO (1) | NO20085045L (es) |
PE (1) | PE20080707A1 (es) |
TW (1) | TW200804310A (es) |
WO (1) | WO2007142904A2 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2882797T3 (es) * | 2009-04-02 | 2021-12-02 | Merck Serono Sa | Inhibidores de dihidroorotato deshidrogenasa |
KR101250606B1 (ko) * | 2011-01-24 | 2013-04-03 | 이화여자대학교 산학협력단 | 5-ht6 수용체 억제 작용을 갖는 신규한 벤조티아졸 및 벤즈이소티아졸유도체, 이의 제조 방법 및 이를 포함하는 약학적 조성물 |
US9890142B2 (en) | 2013-07-10 | 2018-02-13 | Meiji Seika Pharma Co., Ltd. | PDE4 inhibitor |
AU2015286049B2 (en) | 2014-07-08 | 2018-03-01 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic derivatives and pharmaceutical applications thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7582635B2 (en) | 2002-12-24 | 2009-09-01 | Purdue Pharma, L.P. | Therapeutic agents useful for treating pain |
GB0422263D0 (en) * | 2004-10-07 | 2004-11-10 | Glaxo Group Ltd | Novel compounds |
-
2007
- 2007-05-23 PE PE2007000635A patent/PE20080707A1/es not_active Application Discontinuation
- 2007-05-25 TW TW096118646A patent/TW200804310A/zh unknown
- 2007-05-25 CA CA002659701A patent/CA2659701A1/en not_active Abandoned
- 2007-05-25 CN CNA2007800261442A patent/CN101490022A/zh active Pending
- 2007-05-25 AU AU2007255041A patent/AU2007255041A1/en not_active Abandoned
- 2007-05-25 WO PCT/US2007/012569 patent/WO2007142904A2/en active Application Filing
- 2007-05-25 BR BRPI0712444-9A patent/BRPI0712444A2/pt not_active Application Discontinuation
- 2007-05-25 KR KR1020087031621A patent/KR20090023641A/ko not_active Application Discontinuation
- 2007-05-25 JP JP2009513221A patent/JP2009538909A/ja not_active Withdrawn
- 2007-05-25 EP EP07777299A patent/EP2024348A2/en not_active Withdrawn
- 2007-05-25 MX MX2008015328A patent/MX2008015328A/es not_active Application Discontinuation
- 2007-05-31 US US11/809,424 patent/US7501421B2/en not_active Expired - Fee Related
- 2007-05-31 AR ARP070102364A patent/AR061147A1/es unknown
-
2008
- 2008-11-27 IL IL195590A patent/IL195590A0/en unknown
- 2008-12-01 CR CR10474A patent/CR10474A/es not_active Application Discontinuation
- 2008-12-01 EC EC2008008930A patent/ECSP088930A/es unknown
- 2008-12-03 NO NO20085045A patent/NO20085045L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BRPI0712444A2 (pt) | 2012-06-05 |
AR061147A1 (es) | 2008-08-06 |
CA2659701A1 (en) | 2007-12-13 |
US20070281945A1 (en) | 2007-12-06 |
IL195590A0 (en) | 2009-09-01 |
WO2007142904A2 (en) | 2007-12-13 |
PE20080707A1 (es) | 2008-05-22 |
TW200804310A (en) | 2008-01-16 |
ECSP088930A (es) | 2009-01-30 |
NO20085045L (no) | 2008-12-12 |
KR20090023641A (ko) | 2009-03-05 |
AU2007255041A1 (en) | 2007-12-13 |
JP2009538909A (ja) | 2009-11-12 |
US7501421B2 (en) | 2009-03-10 |
CN101490022A (zh) | 2009-07-22 |
EP2024348A2 (en) | 2009-02-18 |
WO2007142904A3 (en) | 2008-02-07 |
MX2008015328A (es) | 2008-12-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal (granting procedure) |