CO6190608A2 - Sal de potasio cristalina de analogos de lipoxina a4 - Google Patents
Sal de potasio cristalina de analogos de lipoxina a4Info
- Publication number
- CO6190608A2 CO6190608A2 CO09057912A CO09057912A CO6190608A2 CO 6190608 A2 CO6190608 A2 CO 6190608A2 CO 09057912 A CO09057912 A CO 09057912A CO 09057912 A CO09057912 A CO 09057912A CO 6190608 A2 CO6190608 A2 CO 6190608A2
- Authority
- CO
- Colombia
- Prior art keywords
- potassium salt
- lipoxine
- formula
- optionally substituted
- substituents selected
- Prior art date
Links
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 title abstract 4
- 239000013078 crystal Substances 0.000 title 1
- 125000001424 substituent group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A61P11/08—Bronchodilators
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87283006P | 2006-12-04 | 2006-12-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6190608A2 true CO6190608A2 (es) | 2010-08-19 |
Family
ID=39076610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO09057912A CO6190608A2 (es) | 2006-12-04 | 2009-06-04 | Sal de potasio cristalina de analogos de lipoxina a4 |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US7906678B2 (https=) |
| EP (2) | EP3489214A1 (https=) |
| JP (1) | JP5410984B2 (https=) |
| KR (3) | KR20090101169A (https=) |
| CN (1) | CN101553456B (https=) |
| AR (1) | AR064116A1 (https=) |
| AU (1) | AU2007327765B2 (https=) |
| BR (1) | BRPI0719679A2 (https=) |
| CA (1) | CA2670791C (https=) |
| CL (1) | CL2007003468A1 (https=) |
| CO (1) | CO6190608A2 (https=) |
| CR (1) | CR10837A (https=) |
| DO (1) | DOP2009000130A (https=) |
| EA (1) | EA018615B1 (https=) |
| EC (1) | ECSP099380A (https=) |
| IL (1) | IL198434A (https=) |
| MA (1) | MA31079B1 (https=) |
| MX (1) | MX2009005911A (https=) |
| MY (1) | MY147951A (https=) |
| NO (1) | NO20092528L (https=) |
| NZ (1) | NZ577338A (https=) |
| PE (2) | PE20120395A1 (https=) |
| SV (1) | SV2009003286A (https=) |
| TN (1) | TN2009000167A1 (https=) |
| TW (1) | TWI415833B (https=) |
| UY (1) | UY30755A1 (https=) |
| WO (1) | WO2008068041A1 (https=) |
| ZA (1) | ZA200904689B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20120395A1 (es) * | 2006-12-04 | 2012-05-23 | Bayer Ip Gmbh | Sal de potasio cristalina de analogos de lipoxina a4 |
| US20090036530A1 (en) * | 2006-12-04 | 2009-02-05 | Bayer Schering Pharma Aktiengesellschaft | Crystalline acid of lipoxin A4 analogs and method of making |
| EP2135610A1 (en) | 2008-06-20 | 2009-12-23 | Laboratorios Almirall, S.A. | Combination comprising DHODH inhibitors and methotrexate |
| EP2470189A4 (en) * | 2009-08-27 | 2013-01-23 | Merck Sharp & Dohme | METHOD FOR PRODUCING PROTEASE INHIBITORS OF HEPATITIS C VIRUS |
| EP2958560B1 (en) * | 2013-02-21 | 2019-05-08 | Forsyth Dental Infirmary for Children | Methods for increasing oral ostenogenesis using lipoxin a4 (lxa4) and its analogs |
| EP3270693B1 (en) * | 2015-03-18 | 2021-06-30 | Forsyth Dental Infirmary for Children | Methods for stabilizing atherosclerotic plaques using lipoxins, resolvins, and analogs thereof |
| ES2827796T3 (es) * | 2016-06-03 | 2021-05-24 | Thetis Pharmaceuticals Llc | Composiciones y procedimientos relativos a sales de mediadores pro-resolutivos especializados de inflamación |
| WO2018144316A1 (en) | 2017-01-31 | 2018-08-09 | The Brigham And Women's Hospital, Inc. | Alx receptor ligands define a biochemical endotype for inflammation-based diseases |
| CN111875530A (zh) * | 2020-08-17 | 2020-11-03 | 浙江朗华制药有限公司 | 一种普拉西坦水合物晶体及其制备方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5650435A (en) * | 1991-04-01 | 1997-07-22 | Madara; James L. | Modulation of inflammation related to columnar epithelia |
| JPH08512023A (ja) | 1993-06-15 | 1996-12-17 | ブリガム・アンド・ウイメンズ・ホスピタル | リポキシン化合物 |
| US5441951A (en) * | 1994-06-15 | 1995-08-15 | Brigham & Women's Hospital | Lipoxin compounds |
| US6048897A (en) | 1993-06-15 | 2000-04-11 | Brigham And Women's Hospital | Lipoxin compounds and their use in treating cell proliferative disorders |
| WO1995001179A1 (en) | 1993-06-29 | 1995-01-12 | Brigham & Women's Hospital | Modulation of inflammation related to columnar epithelia |
| US6008205A (en) | 1997-04-04 | 1999-12-28 | The Brigham & Women's Hospital, Inc. | Polyisoprenyl phosphate stable analogs for regulation of neutrophil responses |
| US6236978B1 (en) * | 1997-11-14 | 2001-05-22 | New York University | System and method for dynamic profiling of users in one-to-one applications |
| US6006466A (en) * | 1998-08-20 | 1999-12-28 | Washecka; John | Concealed linear payout holder for fishing leader |
| SE9900274D0 (sv) | 1999-01-28 | 1999-01-28 | Astra Ab | New compound |
| AU780114B2 (en) | 1999-03-18 | 2005-03-03 | Brigham And Women's Hospital | Regulation of phospholipase D activity |
| CA2675416A1 (en) | 1999-03-18 | 2000-09-21 | Brigham And Women's Hospital | Lipoxin compounds and their use |
| ES2249257T3 (es) | 1999-03-18 | 2006-04-01 | The Brigham And Women's Hospital, Inc. | Utilizacion de compuestos de lipoxina para la inhibicion de la respuesta de los neutrofilos inducida por tnf-alfa. |
| ES2215752T3 (es) | 1999-11-09 | 2004-10-16 | Alcon, Inc | Lipoxina a4 y analogos para el tratamiento del ojo seco. |
| AU2001249329A1 (en) | 2000-03-20 | 2001-10-03 | Brigham And Women's Hospital | Lipoxin analogs and methods for the treatment of periodontal disease |
| US6831186B2 (en) * | 2001-11-06 | 2004-12-14 | Schering Aktiengesellschft | Lipoxin A4 analogs |
| AU2002347539A1 (en) | 2001-12-13 | 2003-06-23 | Ranbaxy Laboratories Limited | Crystalline cefdinir potassium dihydrate |
| JP4634716B2 (ja) | 2002-03-15 | 2011-02-16 | ドクター・レディーズ・ラボラトリーズ・リミテッド | ５−［４−［［３−メチル−４−オキソ−３，４−ジヒドロキナゾリン−２−イル］メトキシ］ベンジル］チアゾリジン−２，４−ジオンカリウム塩の新規な結晶形 |
| SI1589966T1 (sl) | 2003-01-30 | 2011-06-30 | Lek Pharmaceuticals D.D. | Postopek čiščenja losartana |
| WO2006035291A1 (en) | 2004-09-27 | 2006-04-06 | Ranbaxy Laboratories Limited | Crystalline forms of cefdinir potassium |
| US7223718B2 (en) * | 2005-03-07 | 2007-05-29 | Falcon Lab Llc | Enhanced glyphosate herbicidal concentrates |
| WO2007053724A2 (en) | 2005-10-31 | 2007-05-10 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of cefdinir potassium salt |
| PE20120395A1 (es) * | 2006-12-04 | 2012-05-23 | Bayer Ip Gmbh | Sal de potasio cristalina de analogos de lipoxina a4 |
-
2007
- 2007-12-03 PE PE2012000006A patent/PE20120395A1/es not_active Application Discontinuation
- 2007-12-03 US US11/999,000 patent/US7906678B2/en active Active
- 2007-12-03 PE PE2007001704A patent/PE20081200A1/es not_active Application Discontinuation
- 2007-12-03 UY UY30755A patent/UY30755A1/es not_active Application Discontinuation
- 2007-12-03 CL CL200703468A patent/CL2007003468A1/es unknown
- 2007-12-04 JP JP2009539669A patent/JP5410984B2/ja not_active Expired - Fee Related
- 2007-12-04 EP EP18190069.7A patent/EP3489214A1/en not_active Withdrawn
- 2007-12-04 EP EP07847057.2A patent/EP2089350B1/en active Active
- 2007-12-04 MX MX2009005911A patent/MX2009005911A/es active IP Right Grant
- 2007-12-04 CN CN2007800448571A patent/CN101553456B/zh not_active Expired - Fee Related
- 2007-12-04 AR ARP070105403A patent/AR064116A1/es unknown
- 2007-12-04 TW TW096146154A patent/TWI415833B/zh not_active IP Right Cessation
- 2007-12-04 KR KR1020097011427A patent/KR20090101169A/ko not_active Ceased
- 2007-12-04 BR BRPI0719679-2A2A patent/BRPI0719679A2/pt not_active IP Right Cessation
- 2007-12-04 MY MYPI20092224A patent/MY147951A/en unknown
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