CO5690555A2 - Preparacion farmaceutica solida - Google Patents
Preparacion farmaceutica solidaInfo
- Publication number
- CO5690555A2 CO5690555A2 CO06046683A CO06046683A CO5690555A2 CO 5690555 A2 CO5690555 A2 CO 5690555A2 CO 06046683 A CO06046683 A CO 06046683A CO 06046683 A CO06046683 A CO 06046683A CO 5690555 A2 CO5690555 A2 CO 5690555A2
- Authority
- CO
- Colombia
- Prior art keywords
- alkyl
- alkenyl
- group
- pharmaceutical preparation
- heteroaryl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1.- Preparación farmacéutica sólida que contiene uno o varios vehículos y/o coadyuvantes sólidos y un principio activo del grupo de los inhibidores de la reabsorción de neurotransmisores monoamínicos, que presentan una estructura de tropano 2,3-disustituida, que puede obtenerse mediante la aplicación por pulverización de una solución de este principio activo sobre al menos un vehículo.2.- Preparación farmacéutica sólida que contiene uno o varios vehículos y/o coadyuvantes sólidos y un principio activo del grupo de los inhibidores de la reabsorción de neurotransmisores monoamínicos, que presentan una estructura de tropano 2,3-disustituida, caracterizada porque contiene al menos un aglutinante en húmedo.3.- Preparación farmacéutica según las reivindicaciones 1 ó 2, caracterizada porque el principio activo es un compuesto de fórmula Io sus sales por adición de ácido farmacéuticamente aceptables, o sus N-óxidos, en los que R es hidrógeno, alquilo, alquenilo, alquinilo, cicloalquilo, cicloalquilalquilo o 2-hidroxietilo;R3 es CH2-X-RAND#39, en el que X significa O, S, o NR"; en el que R" es hidrógeno o alquilo; y RAND#39 alquilo, alquenilo, alquinilo, cicloalquilo, cicloalquilalquilo o -CO-alquilo; heteroarilo, que puede estar sustituido una o varias veces por alquilo, cicloalquilo o cicloalquilalquilo;fenilo, que puede estar sustituido una o varias veces por un sustituyente seleccionado entre el grupo compuesto por halógeno, CF3, CN, alcoxi, alquilo, alquenilo, alquinilo, amino, nitro y heteroarilo; fenilfenilo; piridilo, que puede estar sustituido una o varias veces por un sustituyente seleccionado entre el grupo compuesto por halógeno, CF3, CN, alcoxi, alquilo, alquenilo, alquinilo, amino, nitro y heteroarilo;tienilo, que puede estar sustituido una o varias veces por un sustituyen te seleccionado entre el grupo compuesto por halógeno, CF3, CN, alcoxi, alquilo, alquenilo, alquinilo, amino, nitro y heteroarilo; o ...
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10353832A DE10353832A1 (de) | 2003-11-18 | 2003-11-18 | Feste pharmazeutische Zubereitungsform |
| DE102004012045A DE102004012045A1 (de) | 2004-03-11 | 2004-03-11 | Feste pharmazeutische Zubereitungsform |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5690555A2 true CO5690555A2 (es) | 2006-10-31 |
Family
ID=34621295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO06046683A CO5690555A2 (es) | 2003-11-18 | 2006-05-16 | Preparacion farmaceutica solida |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20050124651A1 (es) |
| EP (1) | EP1686965A2 (es) |
| JP (2) | JP2007511559A (es) |
| KR (1) | KR20060125805A (es) |
| AR (1) | AR046709A1 (es) |
| AU (1) | AU2004290520A1 (es) |
| BR (1) | BRPI0416691A (es) |
| CA (1) | CA2545513C (es) |
| CO (1) | CO5690555A2 (es) |
| HK (1) | HK1094676A1 (es) |
| IL (1) | IL175246A0 (es) |
| MX (1) | MXPA06005545A (es) |
| NO (1) | NO20062810L (es) |
| NZ (1) | NZ547880A (es) |
| PE (1) | PE20050479A1 (es) |
| RU (1) | RU2377987C2 (es) |
| TW (1) | TW200529844A (es) |
| WO (1) | WO2005049024A2 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ547880A (en) * | 2003-11-18 | 2010-02-26 | Boehringer Ingelheim Int | Solid pharmaceutical preparation form |
| WO2007028769A1 (en) * | 2005-09-05 | 2007-03-15 | Neurosearch A/S | Monoamine neurotransmitter re-uptake inhibitor for neuroprotection |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61227524A (ja) * | 1985-03-30 | 1986-10-09 | Tooa Eiyoo Kk | プラゾシン製剤及びその製法 |
| WO1987004077A1 (en) * | 1986-01-03 | 1987-07-16 | The University Of Melbourne | Gastro-oesophageal reflux composition |
| JPS62221626A (ja) * | 1986-03-20 | 1987-09-29 | Tokyo Tanabe Co Ltd | １，４−ジヒドロピリジン化合物の製剤用組成物 |
| DE3612212A1 (de) * | 1986-04-11 | 1987-10-15 | Basf Ag | Verfahren zur herstellung von festen pharmazeutischen formen |
| DE3830353A1 (de) * | 1988-09-07 | 1990-03-15 | Basf Ag | Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen |
| GEP20001968B (en) * | 1992-01-21 | 2000-03-05 | Glaxo Spa | Arilthio Compounds as Antibacterial and Antiviral Agents |
| JPH07118154A (ja) * | 1993-10-22 | 1995-05-09 | Dainippon Pharmaceut Co Ltd | 固体分散体および粒状製剤 |
| KR100446571B1 (ko) * | 1996-02-22 | 2004-11-03 | 뉴로서치 에이/에스 | 트로판-유도체,이의제조방법및이를포함하는약제학적조성물 |
| FR2762316B1 (fr) * | 1997-04-18 | 1999-12-17 | Sanofi Synthelabo | Derives de 5-aryl-3-(8-azabicyclo[3.2.1] octan-3-yl)-1,3,4- oxadiazol-2(3h)-one, leur preparation et leur application en therapeutique |
| TW580397B (en) * | 1997-05-27 | 2004-03-21 | Takeda Chemical Industries Ltd | Solid preparation |
| EE05442B1 (et) * | 2000-02-29 | 2011-08-15 | Bristol-Myers Squibb Company | Vikeses annuses entekaviiri sisaldav ravimkoostis B-hepatiidi viirusinfektsiooni raviks ning meetod selle valmistamiseks |
| KR100381834B1 (ko) * | 2000-05-20 | 2003-04-26 | 이상득 | 용출성이 개선된 프란루카스트 고체분산체 조성물 및 그제조 방법 |
| US20040106643A1 (en) * | 2001-05-23 | 2004-06-03 | Gouliaev Alex Haarh | Tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| AU2002365288A1 (en) * | 2001-11-30 | 2003-06-10 | Neurosearch A/S | Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases |
| AU2003227520B9 (en) * | 2002-05-30 | 2008-06-26 | Neurosearch A/S | Triple monoamine reuptake inhibitors for the treatment of chronic pain |
| AU2004283425B2 (en) * | 2003-10-16 | 2010-07-08 | Neurosearch A/S | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an acetylcholinesterase inhibitor |
| NZ547880A (en) * | 2003-11-18 | 2010-02-26 | Boehringer Ingelheim Int | Solid pharmaceutical preparation form |
| AU2005205882A1 (en) * | 2004-01-22 | 2005-08-04 | Neurosearch A/S | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an N-methyl-D-aspartate (NMDA) receptors antagonist |
-
2004
- 2004-11-10 NZ NZ547880A patent/NZ547880A/en unknown
- 2004-11-10 CA CA2545513A patent/CA2545513C/en not_active Expired - Fee Related
- 2004-11-10 WO PCT/EP2004/012683 patent/WO2005049024A2/de active Application Filing
- 2004-11-10 RU RU2006121446/15A patent/RU2377987C2/ru not_active IP Right Cessation
- 2004-11-10 MX MXPA06005545A patent/MXPA06005545A/es not_active Application Discontinuation
- 2004-11-10 BR BRPI0416691-4A patent/BRPI0416691A/pt not_active IP Right Cessation
- 2004-11-10 JP JP2006540249A patent/JP2007511559A/ja not_active Withdrawn
- 2004-11-10 KR KR1020067011982A patent/KR20060125805A/ko not_active Application Discontinuation
- 2004-11-10 AU AU2004290520A patent/AU2004290520A1/en not_active Abandoned
- 2004-11-10 EP EP04818766A patent/EP1686965A2/de not_active Withdrawn
- 2004-11-12 US US10/987,831 patent/US20050124651A1/en not_active Abandoned
- 2004-11-16 PE PE2004001120A patent/PE20050479A1/es not_active Application Discontinuation
- 2004-11-17 AR ARP040104232A patent/AR046709A1/es unknown
- 2004-11-17 TW TW093135259A patent/TW200529844A/zh unknown
-
2006
- 2006-04-27 IL IL175246A patent/IL175246A0/en unknown
- 2006-05-16 CO CO06046683A patent/CO5690555A2/es not_active Application Discontinuation
- 2006-06-15 NO NO20062810A patent/NO20062810L/no not_active Application Discontinuation
-
2007
- 2007-01-22 HK HK07100770.9A patent/HK1094676A1/xx not_active IP Right Cessation
-
2010
- 2010-03-24 US US12/730,831 patent/US20100178342A1/en not_active Abandoned
-
2011
- 2011-01-04 JP JP2011000224A patent/JP2011068690A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AR046709A1 (es) | 2005-12-21 |
| NZ547880A (en) | 2010-02-26 |
| WO2005049024A2 (de) | 2005-06-02 |
| AU2004290520A1 (en) | 2005-06-02 |
| TW200529844A (en) | 2005-09-16 |
| NO20062810L (no) | 2006-08-10 |
| US20050124651A1 (en) | 2005-06-09 |
| US20100178342A1 (en) | 2010-07-15 |
| BRPI0416691A (pt) | 2007-01-30 |
| JP2007511559A (ja) | 2007-05-10 |
| WO2005049024A3 (de) | 2006-03-30 |
| HK1094676A1 (en) | 2007-04-04 |
| EP1686965A2 (de) | 2006-08-09 |
| CA2545513A1 (en) | 2005-06-02 |
| CA2545513C (en) | 2013-01-08 |
| RU2377987C2 (ru) | 2010-01-10 |
| IL175246A0 (en) | 2006-10-31 |
| PE20050479A1 (es) | 2005-10-06 |
| JP2011068690A (ja) | 2011-04-07 |
| KR20060125805A (ko) | 2006-12-06 |
| MXPA06005545A (es) | 2006-08-17 |
| RU2006121446A (ru) | 2008-01-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |